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B. Subtilis Competence Info

Competence library

Library Builder D/L & instructions
The B. subtilis reference library

Competence modelling

Pathway or subsystemPathway Builder modelsMathematical modelXPPaut fileNotes
Entire pathwayXML
ComK/Rok/AbrB subsystemXMLWordODE
ComK/Rok/AbrB subsystem rev 3XMLWordODE
ComK/Rok/AbrB subsystem rev 5XMLWordODEModel now has non-competetive binding for AbrB and Rok on comK

Modelling results

Pathway or subsystemDescription of experimentxppaut set fileSystem constantsData, graphs, etc.
ComK/Rok/AbrB subsystemSimulation showing transient spike in ComK with decreasing AbrB concentration (concentration and time values are meaningless - qualitative results only)SETSee SET fileGIF of system response to decreasing AbrB concentration
ComK/Rok/AbrB subsystem rev 5Simulation showing transient spike in ComK with decreasing AbrB concentration with more realistic parameters and time scale (althogh ComK concentration is off by a factor of 10)SETXLSGIF of system response to decreasing AbrB concentration
ComK/Rok/AbrB subsystem rev 5Simulation showing transient spike in ComK with decreasing AbrB concentration with more realistic parameters and time scale (althogh ComK concentration is off by a factor of 10) - added ComK binding to RokSETXLSGIF of system response to decreasing AbrB concentration
ComK/Rok/AbrB subsystem rev 5Simulation showing near-steady state ComK concentrations after 15000 s post T0 as a function of AbrB concentration, which is held constant.SETXLSGIF of ComK concentration as a function of constant AbrB concentration
ComK/Rok/AbrB subsystem rev 51 parameter system sensitivity experiments.SETXLSResults
ComK/Rok/AbrB subsystem rev 52 parameter system sensitivity experiments.SETXLSResults
ComK/Rok/AbrB subsystem rev 5Sensitivity equation results.SETXLSResults