CP 55,940とは 意味・読み方・使い方

CP 55,940 is a cannabinoid which mimics the effects of naturally occurring THC (one of the psychoactive compounds found in marijuana). CP 55,940 was created by Pfizer in 1974 but was never marketed. It is currently used to study the endocannabinoid system. Some effects that have been noted are a greatly decreased rates of lever pressing in exposed mice, and a greater reaction to opiates in exposed mice. CP 55,940 is 45 times more potent than Δ⁹-THC, and fully antagonized by rimonabant (SR141716A). CP 55,940 is considered a full agonist at both CB₁ and CB₂ receptors and has Ki values of 0.58nM and 0.68nM respectively, but interestingly is an antagonist at GPR55, the putative "CB₃" receptor.