sirtinolとは 意味・読み方・使い方

名詞

sirtinol ‎(uncountable)

1. (有機化学) The substituted benzamide 2-[(2-hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide, that is biochemically active
   • 2015 August 6, “Cilostazol Upregulates Autophagy via SIRT1 Activation: Reducing Amyloid-β Peptide and APP-CTFβ Levels in Neuronal Cells”^[1], PLOS ONE, DOI:10.1371/journal.pone.0134486: 

     The present results also showed elevated intracellular Aβ1–42 levels were markedly inhibited by cilostazol and that this inhibition was blocked by KT5720 and sirtinol, indicating that cAMP-dependent protein kinase and SIRT1 underlie the action mechanism of cilostazol, as has been previously reported by Lee et al.