codepletionとは 意味・読み方・使い方

名詞

codepletion ‎(uncountable)

1. (biology) The depletion of one substance in conjunction with the depletion of another.
   • 2016 March 4, “Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells”^[1], PLOS ONE, DOI:10.1371/journal.pone.0150450:

     We found that codepletion of ERG/FLI-1 resulted in inhibition of NR4A1 dependent H3K27ac at distal enhancers of all three induced genes (Fig 6D) and also strongly prevented NR4A1 dependent recruitment of p300 (Fig 6E).