hypercondensationとは 意味・読み方・使い方

名詞

hypercondensation (countable かつ uncountable, 複数形 hypercondensations)

1. (organic chemistry) A class of condensation reaction involving reaction of a carbonyl group with a methylene group to form an alkene with the loss of the elements of water (>C=O + CH₂< -> >C=C<)
2. (genetics) The severe compaction of chromosomes
   • 2015 October 23, “Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells”, in PLOS ONE^[1], DOI:10.1371/journal.pone.0141184:

     In addition, PNAP - 6h decreased CDK1 and cyclin B1 expression, most likely leading to G 2 /M arrest, and induced morphological changes, such as nuclear shrinkage, nuclear fragmentation, and nuclear hypercondensation, as observed by Hoechst 33342 staining.