Bioinformatics Research Group at SRI International

Director: Peter D. Karp, Ph.D.

SRI's Bioinformatics Research Group performs research into new computational methods for bioinformatics. Our interdisciplinary group of scientists also develops bioinformatics software, databases, and ontologies.

Selected Projects

• The BioCyc Collection of Pathway/Genome Databases contains 20,040 databases, including:
  • EcoCyc -- A Model Organism Database for Escherischia coli K-12. The EcoCyc project has integrated information on the E. coli genome, and on the E. coli metabolic and genetic networks from more than 42,000 publications.

  • MetaCyc -- An encyclopedia of 3,105 experimentally elucidated metabolic pathways derived from 3,430 different organisms.

• The Pathway Tools software -- Can be used to query, visualize, and analyze existing Pathway/Genome Databases from the BioCyc collection, and to create new Pathway/Genome Databases for an annotated genome.

• BioWarehouse -- A database interoperation environment that supports data mining and integration of multiple databases including the UniProt, BioCyc, NCBI Taxonomy, Genbank, CMR, ENZYME, Gene Ontology, and KEGG databases.

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