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NZ755880B2 - A diagnostic test reader system - Google Patents
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NZ755880B2 - A diagnostic test reader system - Google Patents

A diagnostic test reader system

Info

Publication number
NZ755880B2
NZ755880B2 NZ755880A NZ75588018A NZ755880B2 NZ 755880 B2 NZ755880 B2 NZ 755880B2 NZ 755880 A NZ755880 A NZ 755880A NZ 75588018 A NZ75588018 A NZ 75588018A NZ 755880 B2 NZ755880 B2 NZ 755880B2
Authority
NZ
New Zealand
Prior art keywords
reader
module
modules
sensor
cartridge
Prior art date
Application number
NZ755880A
Other versions
NZ755880A (en
Inventor
Madsen Niels Kristian Physical Bau
Ole Physical Kring
Original Assignee
Zoetis Services Llc
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Priority claimed from PCT/US2018/018097 external-priority patent/WO2018156395A1/en
Publication of NZ755880A publication Critical patent/NZ755880A/en
Publication of NZ755880B2 publication Critical patent/NZ755880B2/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00306Housings, cabinets, control panels (details)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00326Analysers with modular structure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00792Type of components bearing the codes, other than sample carriers
    • G01N2035/00811Type of components bearing the codes, other than sample carriers consumable or exchangeable components other than sample carriers, e.g. detectors, flow cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N2035/00891Displaying information to the operator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N2035/00891Displaying information to the operator
    • G01N2035/009Displaying information to the operator alarms, e.g. audible
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48785Electrical and electronic details of measuring devices for physical analysis of liquid biological material not specific to a particular test method, e.g. user interface or power supply
    • G01N33/48792Data management, e.g. communication with processing unit
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00594Quality control, including calibration or testing of components of the analyser
    • G01N35/00613Quality control
    • G01N35/00623Quality control of instruments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00871Communications between instruments or with remote terminals
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D3/00Control of position or direction
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06QINFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q10/00Administration; Management
    • G06Q10/08Logistics, e.g. warehousing, loading or distribution; Inventory or stock management

Abstract

diagnostic test reader system including two or more reader modules and at least one mother module is provided. Each of the reader modules includes a unique code and is configured for reading a specific test cartridge type. Each of the reader modules is configured to be in data communication with the mother module for receiving instructions from the mother module and for transmitting read and/or derived data to the mother module. The mother module is configured for communicating individually with each of the reader modules. Each of the reader modules are physically separate boxes each having separate electronic circuits and drivers for performing respective diagnostic tests, each reader module having a slot for receiving respective test cartridges. At least one of the reader modules comprises a sensor for detecting position data representing its spatial position relative to at least one other of the reader modules, said sensor of said at least one reader module being configured for transmitting said position data comprising said respective spatial position relative to at least one other of the reader modules to said mother module. At least one other of the reader modules has one or more fiducial marks detectable by said sensor.

Claims (31)

1. A diagnostic test reader system comprising a plurality of modules, including a plurality of reader modules and at least one mother module, each of the reader modules having a unique code and being configured to read a specific test cartridge type, each of the 5 reader modules being in data communication with the mother module for receiving instructions from the mother module and for transmitting at least one of read and derived data to the mother module, the mother module being configured to communicate individually with each of the reader modules, wherein the reader modules are physically separate boxes each having separate 10 electronic circuits and drivers for performing respective diagnostic tests, each reader module having a slot for receiving respective test cartridges, and further wherein at least one of the reader modules comprises a sensor for detecting position data representing its spatial position relative to at least one other of the reader modules, said sensor of said at least one reader module being configured for transmitting said 15 position data comprising said respective spatial position relative to at least one other of the reader modules to said mother module, wherein at least one other of the reader modules has one or more fiducial marks detectable by said sensor.
2. The reader system of claim 1, wherein said sensor of said reader module is configured for detecting position data representing its spatial position relative to at least one other of the 20 reader modules when it is arranged within a distance of up to about 10 cm.
3. The reader system of claim 1 or 2, wherein said sensor of the reader module is configured for detecting said unique code of at least one other of the reader modules, and said sensor being configured for transmitting said detected unique code of at least one other of the reader modules to the mother module. 25
4. The reader system of claim 3, wherein said sensor is configured for detecting position data representing its spatial position relative to at least one other of the reader modules, sensing said unique code of said same of the at least one other of the reader modules and transmitting at least one set of neighbour data, wherein each set of neighbour data comprises said position data and said unique code of said same reader module.
5. The reader system of claim 3 or 4, wherein the sensor or each sensor of the one or more reader modules is configured for detecting orientation data representing the relative 5 orientation between the respective modules and for transmitting the orientation data to the mother module, and the mother module is configured for determining the relative orientation between two or more reader modules based on said orientation data.
6. The reader system of claim 4 or claim 5, wherein each set of neighbour data comprises position data representing the spatial position of the sensor relative to one other 10 reader module associated with said unique code of said same other reader module, preferably each set of neighbour data comprises position data representing the spatial position of the sensor relative to one other reader module associated with said unique code of said same other reader module and orientation data representing the relative orientation between the module comprising said sensor and the reader module associated with said unique code. 15
7. The reader system of any one of the preceding claims, wherein at least two of the reader modules each comprise a sensor for detecting position data representing its spatial position relative to at least one other of the reader modules, said respective sensors of said respective reader modules being configured for transmitting said position data comprising position data representing said respective spatial position relative to at least one other of the 20 reader modules to said mother module.
8. The reader system of claim 7, wherein each sensor is configured for detecting position data representing its spatial position relative to at least one other of the reader modules together with the unique code of said at least one other of the reader modules and for generating and transmitting at least one set of neighbour data, each set of neighbour data 25 comprises said position data representing said spatial position of the sensor relative to one other reader module associated with said unique code of said same other reader module.
9. The reader system of any one of claims 2-8, wherein said sensor is a tactile sensor, an optical sensor, a magnetic sensor or a radio-frequency sensor, a Bluetooth sensor or any combinations thereof.
10. The reader system of any one of claims 2 -9, wherein said sensor comprises a 5 transceiver, and comprises said respective unique code, wherein one or more of said reader modules comprise one or more passive chips comprising said respective unique code.
11. The reader system of any one of the preceding claims, wherein said system comprises at least three reader modules.
12. The reader system of any one of the preceding claims, wherein said reader modules 10 are adapted to be stacked.
13. The reader system of any one of the preceding claims, wherein said mother module is configured for determining the relative spatial positions of said reader modules, said mother module is configured for determining if the relative spatial positions of said reader modules fulfil at least one predefined requirement, and said at least one predefined requirement is 15 fulfilled when the reader modules are stacked in a predefined configuration, said at least one predefined requirement comprises at least one pre-programmed requirement or at least one user selectable requirement.
14. The reader system of claim 13, wherein said mother module is configured for determining the relative spatial positions of said reader modules at least partly via said 20 sensors of said respective reader modules.
15. The reader system of claim 13 or claim 14, wherein said mother module is configured for receiving one or more sets of neighbour data and based on said received sets of neighbour determining the relative spatial positions of said reader modules and determining if the relative spatial positions of said reader modules fulfil the predefined requirement. 25
16. The reader system of any one of claims 13-15, wherein said mother module is configured for triggering an alarm if said at least one predefined requirement is not fulfilled, said alarm being a visual alarm or an audible alarm.
17. The reader system of any one of the preceding claims, wherein said reader modules comprise two or more of the reader module types selected from a microfluidic test cartridge reader module, a lateral flow test cartridge reader module, a vertical flow test cartridge reader, a fluorescent test cartridge reader module, a flow through test cartridge reader module, a flow 5 cytometry cartridge reader module, an electrical read out test cartridge reader module, an imaging read out cartridge reader module, an electrochemical read out cartridge reader module, a light absorption cartridge reader module, magnetically assisted cartridge reader module, a snap type cartridge test or a combination thereof.
18. The reader system of any one of the preceding claims, wherein said reader system 10 comprises two or more of the same reader module type.
19. The reader system of any one of the preceding claims, wherein said reader system comprises two or more different reader module types, and each reader module of the same type comprises an identical visual tag coding for the reader module type, and each reader module of the same type comprises an identical colour coding for the reader module type. 15
20. The reader system of any one of the preceding claims, wherein said mother module is associated with a user interface, and comprises at least one of a screen, a keyboard, an audible user interface, a video interface and a printer.
21. The reader system of any one of the preceding claims, wherein said mother module is associated with a screen with a graphical user interface comprising an icon for each of the 20 reader modules including an indication showing if the respective reader module is operating and including a time indicator indicating when the respective operating reader is expected to terminate its present operation.
22. The reader system of any one of the preceding claims, wherein said mother module is in data communication with a user database, said user database comprises user identification 25 and associated user authorization for each user, the user authorization comprising an indication of at least one reader module which a user with the associated user identification is qualified for using.
23. The reader system of claim 22, wherein at least one of the reader modules requires that a user has a user authorization registered in said user database and that said user is approved by said mother module by presenting a user code in the form of a pin code, a chip or a bar code. 5
24. The reader system of any one of the preceding claims, wherein said mother module comprises a bar code reader.
25. The reader system of any one of the preceding claims, wherein said mother module is in data communication with a cartridge database, said cartridge database comprises cartridge identification and associated reader module data providing that when identifying a cartridge 10 to said mother module, the mother module is configured for assigning a reader module for operating a given test using said cartridge, and said identification of said cartridge comprises reading a barcode associated with said cartridge by said bar code reader.
26. The reader system of any one of the preceding claims, wherein said mother module is in data communication with a patient database, said patient database comprises patient 15 identification associated with patient data for a plurality of patients, said mother module is configured for storing a test result of a specific patient in said patient database and ensuring that the test result is associated with said specific patient.
27. The reader system of claim 26, wherein the mother module is configured for extracting data from the patient database and transmitting the data to a reader module for 20 running a test.
28. The reader system of any one of the preceding claims, wherein the mother module is configured for extracting data from a general statistics patient database and transmitting the data to a reader module for running a test.
29. The reader system of any one of the preceding claims, wherein the mother module is 25 in connection with the internet, and in contact with one or more web databases.
30. The reader system of any one of the preceding claims, wherein at least one of the reader modules is configured for transmitting a test initiating signal upon sensing that a cartridge has been inserted into its slot, and said reader module is configured for transmitting test status to said mother module comprising progress of a test running on said cartridge.
31. The reader system of claim 1, substantially as herein described with reference to any one of the
NZ755880A 2018-02-14 A diagnostic test reader system NZ755880B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762461316P 2017-02-21 2017-02-21
PCT/US2018/018097 WO2018156395A1 (en) 2017-02-21 2018-02-14 A diagnostic test reader system

Publications (2)

Publication Number Publication Date
NZ755880A NZ755880A (en) 2025-08-29
NZ755880B2 true NZ755880B2 (en) 2025-12-02

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