NZ770696B2 - Dual-stage syringes for independent delivery of two or more fluids - Google Patents
Dual-stage syringes for independent delivery of two or more fluids Download PDFInfo
- Publication number
- NZ770696B2 NZ770696B2 NZ770696A NZ77069619A NZ770696B2 NZ 770696 B2 NZ770696 B2 NZ 770696B2 NZ 770696 A NZ770696 A NZ 770696A NZ 77069619 A NZ77069619 A NZ 77069619A NZ 770696 B2 NZ770696 B2 NZ 770696B2
- Authority
- NZ
- New Zealand
- Prior art keywords
- stage
- dual
- primary piston
- boundary
- syringe
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title abstract 2
- 239000012528 membrane Substances 0.000 claims 1
- 230000009977 dual effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00529—Liver
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
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Abstract
the present disclosure, embodiments of dual-stage syringes are disclosed along with delivery systems incorporating a sleeved dual-stage syringe, turn key dual stage syringe and delivery system, including an external barrel having a primary chamber, a primary piston having a secondary chamber, the primary piston adapted to receive a secondary piston and a locking sleeve having a locking features defining first and second boundaries and at least three stages including an initial stage, an intermediate stage and a final stage. Other embodiments of the dual-stage syringes described herein include ratcheting safety tabs, methods of determining flow parameters of administered fluid from a syringe, and an integrated one-way valve dual staged syringe.
Claims (16)
1. A sleeved dual-stage syringe comprising: an external barrel having a primary chamber defined through the external barrel from a proximal opening of the external barrel to a distal opening of the external barrel; a primary piston having a secondary chamber defined through the primary piston from a proximal opening of the primary piston to a sealed distal end of the primary piston, the primary piston configured to receive a secondary piston through the proximal opening of the primary piston; and a locking sleeve disposed within the primary chamber, wherein: the primary piston and the locking sleeve comprise a locking mechanism configured to define a first boundary, a second boundary distal to the first boundary, and at least three stages, the at least three stages comprising: an initial stage wherein the primary piston is inserted proximal to the first boundary and is freely movable distally or proximally; an intermediate stage wherein the primary piston is inserted distal to the first boundary and is prevented from moving proximally beyond the first boundary; and a final stage wherein the primary piston is inserted distal to the second boundary and is prevented from moving proximally beyond the second boundary.
2. The sleeved dual-stage syringe of claim 1, wherein the locking mechanism comprises a body portion having a shape conforming to contours of the external barrel.
3. The sleeved dual-stage syringe of claim 1, wherein the locking mechanism comprises one or more features for integrational assembly. 20666438_1 (GHMatters) P114940.NZ
4. The sleeved dual-stage syringe of claim 3, wherein the locking mechanism comprises a proximal ridge configured to seat the locking mechanism in the proximal opening of the external barrel.
5. The sleeved dual-stage syringe of claim 2, wherein the locking mechanism comprises distal catch members.
6. The sleeved dual-stage syringe of claim 5, wherein the distal catch members comprise catches of varying lengths around the circumference of the body portion at the distal end of the body portion.
7. The sleeved dual-stage syringe of claim 5, wherein the distal catch members comprise long catches and short catches alternating around the circumference of the body portion at the distal end of the body portion.
8. The sleeved dual-stage syringe of claim 7, wherein long-catch ends of the long catches, short-catch ends of the short catches, or both are angled inwardly of the sleeved dual-stage syringe.
9. The sleeved dual-stage syringe of claim 7, wherein long-catch ends of the long catches, short-catch ends of the short catches, or both are angled outwardly of the sleeved dual-stage syringe.
10. The sleeved dual-stage syringe of claim 1, further comprising one or more sensors.
11. The sleeved dual-stage syringe of claim 1, wherein the external barrel further comprises shielding.
12. A delivery system comprising: a system housing; and a dual-stage syringe housed within the system housing, the dual-stage syringe comprising 20666438_1 (GHMatters) P114940.NZ an external barrel having a primary chamber defined through the external barrel from a proximal opening of the external barrel to a distal opening of the external barrel; a primary piston having a secondary chamber defined through the primary piston from a proximal opening of the primary piston to a sealed distal end of the primary piston, the primary piston configured to receive a secondary piston through the proximal opening of the primary piston; and a locking sleeve disposed within the primary chamber, wherein: the primary piston and the locking sleeve comprise locking features configured to define a first boundary, a second boundary distal to the first boundary, and at least three stages, the at least three stages comprising: an initial stage wherein the primary piston is inserted proximal to the first boundary and is freely movable distally or proximally; an intermediate stage wherein the primary piston is inserted distal to the first boundary and is prevented from moving proximally beyond the first boundary; and a final stage wherein the primary piston is inserted distal to the second boundary and is prevented from moving proximally beyond the second boundary.
13. The delivery system of claim 12, further comprising orientation features configured to orient the dual-stage syringe within the system housing.
14. The delivery system of claim 12, further comprising locking features configured lock the dual-stage syringe in place within the system housing.
15. The delivery system of claim 12, further comprising membrane technology.
16. The delivery system of claim 12, further comprising one or more sensors. 20666438_1 (GHMatters) P114940.NZ
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862673632P | 2018-05-18 | 2018-05-18 | |
| US201862673628P | 2018-05-18 | 2018-05-18 | |
| PCT/US2019/032983 WO2019222699A1 (en) | 2018-05-18 | 2019-05-17 | Dual-stage syringes for independent delivery of two or more fluids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NZ770696A NZ770696A (en) | 2024-05-31 |
| NZ770696B2 true NZ770696B2 (en) | 2024-09-03 |
Family
ID=
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