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NZ794050B2 - Charge-bearing cyclodextrin polymeric materials and methods of making and using same - Google Patents
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NZ794050B2 - Charge-bearing cyclodextrin polymeric materials and methods of making and using same - Google Patents

Charge-bearing cyclodextrin polymeric materials and methods of making and using same

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Publication number
NZ794050B2
NZ794050B2 NZ794050A NZ79405020A NZ794050B2 NZ 794050 B2 NZ794050 B2 NZ 794050B2 NZ 794050 A NZ794050 A NZ 794050A NZ 79405020 A NZ79405020 A NZ 79405020A NZ 794050 B2 NZ794050 B2 NZ 794050B2
Authority
NZ
New Zealand
Prior art keywords
polymeric material
porous polymeric
cyclodextrin
moiety
fluid sample
Prior art date
Application number
NZ794050A
Other versions
NZ794050A (en
Inventor
Gokhan BARIN
Moira Brown
Shan Li
Jason M Spruell
Original Assignee
Cyclopure Inc
Filing date
Publication date
Application filed by Cyclopure Inc filed Critical Cyclopure Inc
Priority to NZ817580A priority Critical patent/NZ817580B2/en
Publication of NZ794050A publication Critical patent/NZ794050A/en
Publication of NZ794050B2 publication Critical patent/NZ794050B2/en

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Abstract

The present disclosure relates to charge-bearing polymeric materials and methods of their use for purifying fluid samples from micropollulants, such as anionic micropollutants.

Claims (30)

CLAIMS :
1. A porous polymeric material comprising a plurality of cyclodextrins crosslinked with a plurality of polyisocyanate crosslinkers, wherein one or more of the plurality of cyclodextrins are bound to a linker of formula (I): wherein A is an aryl or heteroaryl moiety; each R1 is independently selected from the group consisting of H, C1-C6 alkyl, C1-C3 haloalkyl, aryl, heteroaryl, -CF3, -SO3H, –CN, -NO2, -NH2, -NCO, -C(O)2R3, -C(O)N(R3)2, and – halogen; each R2 is independently H, -OH, -O-metal cation, alkyl, aryl, heteroaryl, -SH, al cation, –S-alkyl, -C(O)2H, or -C(O)NH2; each R3 is independently –H, –C1-C6 alkyl, –C1-C3 haloalkyl, –aryl, -C(O)N(Ra)(Rb), or Ra)(Rb), wherein each Ra and Rb is independently H, or C1-C6 alkyl; each W is independently a bond, an alkylene group, an arylene group, a heteroarylene group, -O-arylene-, a-arylene-, -SO2-arylene-, -NH-arylene-, lene-, -O- heteroarylene-, -(CH2)a-heteroarylene-, -SO2-heteroarylene-, -NH-heteroarylene-, -S- heteroarylene-, –(–O–(CH2)a–)x–, (CH2)a–)x–, –(–S–(CH2)a–)x–, , or , wherein a is 0-100 and x is 1-100, and each arylene or heteroarylene moiety can be substituted or unsubstituted; each Z is an anionic moiety; each L is ; A’ is a covalent bond to A; Z’ is a covalent bond to Z; * is a nt bond to ; is a point of attachment to the plurality of cyclodextrin carbon atoms; x is 0-8; y1 is 1-4; y2 is 1-4; and y3 is 0-4.
2. The porous polymeric material of claim 1, wherein each Z is , , , , , , or .
3. The porous polymeric material of claim 1, wherein each cyclodextrin is selected from the group consisting of a-cyclodextrin, ß-cyclodextrin, ?-cyclodextrin, and ations thereof.
4. The porous polymeric al of claim 1, wherein x and y3 are each 0.
5. The porous polymeric material of claim 1, wherein the aryl moiety is , , , , , , , , , , , , , , , , , , , or , wherein represents any of the substituents attached to A in formula (I).
6. The porous ric material of claim 5, wherein the polyisocyanate crosslinker is 4,4’- methylene diphenyl diisocyanate, the aryl moiety is and x and y3 are each 0.
7. The porous polymeric material of claim 6, wherein each cyclodextrin is a ß-cyclodextrin.
8. The porous ric material of claim 5, wherein the polyisocyanate crosslinker is toluene 2,4-diisocyanate, the aryl moiety is and x and y3 are each 0.
9. The porous polymeric material of claim 8, wherein each cyclodextrin is a ß-cyclodextrin.
10. The porous polymeric material of claim 1, wherein the polymer has a surface area from about 10 m2/g to about 2,000 m2/g.
11. A porous ric material comprising a plurality of cyclodextrins crosslinked with a ity of acid chloride-containing crosslinkers or ester-containing crosslinkers, wherein one or more of the plurality of cyclodextrins are bound to a linker of formula (I): A is an aryl or heteroaryl moiety; each R1 is independently selected from the group consisting of H, C1-C6 alkyl, C1-C3 haloalkyl, aryl, heteroaryl, -CF3, -SO3H, –CN, -NO2, -NH2, -NCO, -C(O)2R3, -C(O)N(R3)2, and – halogen; each R2 is independently H, -OH, -O-metal cation, alkyl, aryl, heteroaryl, -SH, –S-metal cation, –S-alkyl, -C(O)2H, or -C(O)NH2; each R3 is independently –H, –C1-C6 alkyl, –C1-C3 haloalkyl, –aryl, (Ra)(Rb), or Ra)(Rb), wherein each Ra and Rb is independently H, or C1-C6 alkyl; each W is independently a bond, an alkylene group, an arylene group, a arylene group, -O-arylene-, -(CH2)a-arylene-, -SO2-arylene-, -NH-arylene-, -S-arylene-, -O- heteroarylene-, -(CH2)a-heteroarylene-, -SO2-heteroarylene-, -NH-heteroarylene-, -S- heteroarylene-, –(–O–(CH2)a–)x–, –(–NH–(CH2)a–)x–, –(–S–(CH2)a–)x–, , or , wherein a is 0-100 and x is 1-100, and each arylene or heteroarylene moiety can be substituted or unsubstituted; each Z is a cationic or anionic moiety; each L is or ; A’ is a covalent bond to A; Z’ is a covalent bond to Z; * is a covalent bond to ; is a point of attachment to the plurality of cyclodextrin carbon atoms; x is 0-8; y1 is 1-4; y2 is 1-4; and y3 is 0-4.
12. The porous ric al of claim 11, wherein each Z is an anionic moiety and the c moiety is , , , , , , or .
13. The porous polymeric material of claim 11, wherein each Z is a ic moiety and the cationic moiety is –N(R3)3+, –P(R3)3+, –S(R3)2+, or -Heteroaryl+.
14. The porous polymeric material of claim 13, wherein each cationic moiety is –N(R3)3+.
15. The porous polymeric material of claim 13, wherein each cationic moiety is –N(Me)3+.
16. The porous ric material of claim 11, wherein each cyclodextrin is selected from the group consisting of a-cyclodextrin, ß-cyclodextrin, ?-cyclodextrin, and combinations thereof.
17. The porous polymeric al of claim 11, wherein x and y3 are each 0.
18. The porous polymeric material of claim 11, wherein the aryl moiety is , , , , , or , wherein represents any of the substituents attached to A in a (I).
19. The porous polymeric material of claim 18, wherein the aryl moiety is or , and x and y3 are each 0.
20. The porous polymeric material of claim 19, wherein each cyclodextrin is a ß- cyclodextrin.
21. The porous polymeric material of claim 18, wherein the aryl moiety is and x and y3 are each 0.
22. The porous polymeric material of claim 21, wherein each cyclodextrin is a ßcyclodextrin.
23. The porous polymeric material of claim 18, wherein the aryl moiety is and x and y3 are each 0.
24. The porous ric al of claim 23, wherein each cyclodextrin is a ß- cyclodextrin.
25. The porous polymeric material of claim 11, wherein the polymer has a surface area from about 10 m2/g to about 2,000 m2/g.
26. A method of purifying a fluid sample comprising one or more pollutants, the method comprising contacting the fluid sample with the porous polymeric material of claim 1, whereby at least 50 wt. % of the total amount of the one or more pollutants in the fluid sample is ed by the porous polymeric material.
27. A method of purifying a fluid sample comprising one or more pollutants, the method comprising ting the fluid sample with the porous ric material of claim 7, whereby at least 50 wt. % of the total amount of the one or more pollutants in the fluid sample is adsorbed by the porous polymeric material.
28. A method of purifying a fluid sample comprising one or more pollutants, the method comprising contacting the fluid sample with the porous polymeric material of claim 11, whereby at least 50 wt. % of the total amount of the one or more pollutants in the fluid sample is adsorbed by the porous polymeric material.
29. A method of purifying a fluid sample sing one or more pollutants, the method comprising contacting the fluid sample with the porous polymeric material of claim 22, whereby at least 50 wt. % of the total amount of the one or more pollutants in the fluid sample is adsorbed by the porous polymeric material.
30. A method of purifying a fluid sample comprising one or more pollutants, the method comprising contacting the fluid sample with the porous polymeric material of claim 24, y at least 50 wt. % of the total amount of the one or more pollutants in the fluid sample is adsorbed by the porous polymeric material. ?x;a? ?x? '1‘ - ‘~ :3}:
NZ794050A 2020-02-13 Charge-bearing cyclodextrin polymeric materials and methods of making and using same NZ794050B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ817580A NZ817580B2 (en) 2020-02-13 Charge-bearing cyclodextrin polymeric materials and methods of making and using same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962805505P 2019-02-14 2019-02-14
NZ778750A NZ778750B2 (en) 2020-02-13 Charge-bearing cyclodextrin polymeric materials and methods of making and using same

Publications (2)

Publication Number Publication Date
NZ794050A NZ794050A (en) 2025-08-29
NZ794050B2 true NZ794050B2 (en) 2025-12-02

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