SG11201400092VA - Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them - Google Patents
Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising themInfo
- Publication number
- SG11201400092VA SG11201400092VA SG11201400092VA SG11201400092VA SG11201400092VA SG 11201400092V A SG11201400092V A SG 11201400092VA SG 11201400092V A SG11201400092V A SG 11201400092VA SG 11201400092V A SG11201400092V A SG 11201400092VA SG 11201400092V A SG11201400092V A SG 11201400092VA
- Authority
- SG
- Singapore
- Prior art keywords
- pyrazolo
- pyridines
- tetrahydro
- medicament
- substituted
- Prior art date
Links
- VGMJQHONPAXABH-UHFFFAOYSA-N 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridine Chemical class C1NCCC2=C1C=NN2 VGMJQHONPAXABH-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2011/066061 WO2013037415A1 (en) | 2011-09-16 | 2011-09-16 | Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201400092VA true SG11201400092VA (en) | 2014-07-30 |
Family
ID=44653324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201400092VA SG11201400092VA (en) | 2011-09-16 | 2011-09-16 | Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9127001B2 (en) |
| EP (1) | EP2755973B1 (en) |
| JP (1) | JP5957525B2 (en) |
| KR (1) | KR20140077912A (en) |
| CN (1) | CN103930421B (en) |
| AU (1) | AU2011376721B2 (en) |
| CA (1) | CA2846366A1 (en) |
| CY (1) | CY1117396T1 (en) |
| DK (1) | DK2755973T3 (en) |
| ES (1) | ES2559450T3 (en) |
| HR (1) | HRP20160049T1 (en) |
| HU (1) | HUE028378T2 (en) |
| IL (1) | IL231050A (en) |
| PL (1) | PL2755973T3 (en) |
| PT (1) | PT2755973E (en) |
| SG (1) | SG11201400092VA (en) |
| SI (1) | SI2755973T1 (en) |
| WO (1) | WO2013037415A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011376721B2 (en) | 2011-09-16 | 2017-06-08 | Sanofi | Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them |
| US9016191B2 (en) | 2012-04-20 | 2015-04-28 | Robert S. Krolick | Portable baking oven |
| EP3134406A1 (en) * | 2014-04-24 | 2017-03-01 | Dart Neuroscience (Cayman) Ltd | Substituted 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole and 4,5,6,7-tetrahydro-2h-pyrazolo [4,3-c]pyridine compounds as glyt1 inhibitors |
| EP3215500A1 (en) | 2014-11-05 | 2017-09-13 | Dart NeuroScience (Cayman) Ltd. | Substituted azetidinyl compounds as glyt1 inhibitors |
| WO2016109684A2 (en) | 2014-12-30 | 2016-07-07 | Novira Therapeutics, Inc. | Derivatives and methods of treating hepatitis b infections |
| WO2017097671A1 (en) * | 2015-12-10 | 2017-06-15 | Bayer Pharma Aktiengesellschaft | Substituted perhydropyrrolo[3,4-c]pyrrole derivatives and the use of same |
| JP2018536693A (en) | 2015-12-10 | 2018-12-13 | バイエル・ファルマ・アクティエンゲゼルシャフト | 2-Phenyl-3- (piperazinomethyl) imidazo [1,2-a] pyridine derivatives as blockers of TASK-1 and TASK-2 channels for treating sleep-related breathing disorders |
| JOP20190005A1 (en) * | 2016-07-20 | 2019-01-20 | Bayer Ag | Substituted diazahetero-bicyclic compounds and their use |
| WO2018227427A1 (en) * | 2017-06-14 | 2018-12-20 | Bayer Aktiengesellschaft | Substituted bridged diazepane derivatives and use thereof |
| JOP20190284A1 (en) | 2017-06-14 | 2019-12-11 | Bayer Pharma AG | Diazabicyclic substituted imidazopyrimidines and their use for the treatment of breathing disorders |
| WO2019073058A1 (en) * | 2017-10-12 | 2019-04-18 | Universität Heidelberg | Kcnk3-based gene therapy of cardiac arrhythmia |
| IL312642A (en) | 2021-11-12 | 2024-07-01 | Insilico Medicine Ip Ltd | Small molecule inhibitors of ubiquitin-specific protease 1 (USP1) and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK27383A (en) | 1982-02-17 | 1983-08-18 | Lepetit Spa | PROCEDURE FOR PREPARING PYRAZOLE (4,3-C) PYRIDINES |
| DE10332685A1 (en) | 2003-07-18 | 2005-02-17 | Bayer Healthcare Ag | Use of a modulator of specific potassium channels, expressed preferentially in the atrium, for treatment and prevention of arrhythmia, coronary disease and hypertension |
| US7772232B2 (en) * | 2004-04-15 | 2010-08-10 | Bristol-Myers Squibb Company | Quinazolinyl compounds as inhibitors of potassium channel function |
| DE102005028862A1 (en) * | 2005-06-22 | 2007-01-11 | Sanofi-Aventis Deutschland Gmbh | Substituted heterocycles, their use as medicament and pharmaceutical compositions containing them |
| DE102005028845A1 (en) | 2005-06-22 | 2006-12-28 | Sanofi-Aventis Deutschland Gmbh | New substituted pyrrolidin-2-ones, piperidin-2-ones and isothiazolidine-1,1-dioxides useful for treating e.g. dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, breast cancer and heart failure |
| BRPI0710946A2 (en) | 2006-04-27 | 2012-03-06 | Sanofi-Aventis Deutschland Gmbh | Ion channel inhibitors task-1 and task-3 |
| WO2011115804A1 (en) | 2010-03-17 | 2011-09-22 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| AU2011376721B2 (en) | 2011-09-16 | 2017-06-08 | Sanofi | Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them |
-
2011
- 2011-09-16 AU AU2011376721A patent/AU2011376721B2/en not_active Ceased
- 2011-09-16 ES ES11757858.3T patent/ES2559450T3/en active Active
- 2011-09-16 DK DK11757858.3T patent/DK2755973T3/en active
- 2011-09-16 HU HUE11757858A patent/HUE028378T2/en unknown
- 2011-09-16 KR KR20147009651A patent/KR20140077912A/en not_active Withdrawn
- 2011-09-16 CN CN201180074839.4A patent/CN103930421B/en not_active Expired - Fee Related
- 2011-09-16 SI SI201130717T patent/SI2755973T1/en unknown
- 2011-09-16 EP EP11757858.3A patent/EP2755973B1/en active Active
- 2011-09-16 PT PT117578583T patent/PT2755973E/en unknown
- 2011-09-16 PL PL11757858T patent/PL2755973T3/en unknown
- 2011-09-16 CA CA 2846366 patent/CA2846366A1/en not_active Abandoned
- 2011-09-16 JP JP2014530104A patent/JP5957525B2/en not_active Expired - Fee Related
- 2011-09-16 HR HRP20160049TT patent/HRP20160049T1/en unknown
- 2011-09-16 WO PCT/EP2011/066061 patent/WO2013037415A1/en not_active Ceased
- 2011-09-16 US US14/342,744 patent/US9127001B2/en active Active
- 2011-09-16 SG SG11201400092VA patent/SG11201400092VA/en unknown
-
2014
- 2014-02-19 IL IL231050A patent/IL231050A/en not_active IP Right Cessation
-
2015
- 2015-08-10 US US14/822,361 patent/US9598410B2/en active Active
-
2016
- 2016-02-03 CY CY20161100094T patent/CY1117396T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9127001B2 (en) | 2015-09-08 |
| CN103930421A (en) | 2014-07-16 |
| JP5957525B2 (en) | 2016-07-27 |
| PL2755973T3 (en) | 2016-04-29 |
| HRP20160049T1 (en) | 2016-02-12 |
| HUE028378T2 (en) | 2016-12-28 |
| AU2011376721A1 (en) | 2014-04-03 |
| IL231050A0 (en) | 2014-03-31 |
| US20140330009A1 (en) | 2014-11-06 |
| CN103930421B (en) | 2016-06-29 |
| EP2755973A1 (en) | 2014-07-23 |
| AU2011376721B2 (en) | 2017-06-08 |
| PT2755973E (en) | 2016-02-16 |
| CY1117396T1 (en) | 2017-04-26 |
| HK1194740A1 (en) | 2014-10-24 |
| CA2846366A1 (en) | 2013-03-21 |
| IL231050A (en) | 2016-06-30 |
| EP2755973B1 (en) | 2015-11-04 |
| SI2755973T1 (en) | 2016-02-29 |
| WO2013037415A1 (en) | 2013-03-21 |
| DK2755973T3 (en) | 2016-01-25 |
| JP2014526479A (en) | 2014-10-06 |
| ES2559450T3 (en) | 2016-02-12 |
| US20160060259A1 (en) | 2016-03-03 |
| US9598410B2 (en) | 2017-03-21 |
| KR20140077912A (en) | 2014-06-24 |
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