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AU2014243418B2 - Modified binding proteins inhibiting the VEGF-A receptor interaction - Google Patents
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AU2014243418B2 - Modified binding proteins inhibiting the VEGF-A receptor interaction - Google Patents

Modified binding proteins inhibiting the VEGF-A receptor interaction

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Publication number
AU2014243418B2
AU2014243418B2 AU2014243418A AU2014243418A AU2014243418B2 AU 2014243418 B2 AU2014243418 B2 AU 2014243418B2 AU 2014243418 A AU2014243418 A AU 2014243418A AU 2014243418 A AU2014243418 A AU 2014243418A AU 2014243418 B2 AU2014243418 B2 AU 2014243418B2
Authority
AU
Australia
Prior art keywords
binding proteins
vegf
binding
receptor interaction
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014243418A
Other versions
AU2014243418A1 (en
Inventor
Hans Kaspar Binz
Patrik Forrer
Michael Tobias Stumpp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Partners AG
Original Assignee
Molecular Partners AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2011247563A external-priority patent/AU2011247563B2/en
Application filed by Molecular Partners AG filed Critical Molecular Partners AG
Priority to AU2014243418A priority Critical patent/AU2014243418B2/en
Publication of AU2014243418A1 publication Critical patent/AU2014243418A1/en
Application granted granted Critical
Publication of AU2014243418B2 publication Critical patent/AU2014243418B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

MODIFIED BINDING PROTEINS INHIBITING THE VEGF-A RECEPTOR INTERACTION The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a polyethylene glycol moiety and a binding domain, which inhibits VEGF-Axxx binding to VEGFR-2. Examples of such recombinant binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity, and a polyethylene glycol moiety. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.
AU2014243418A 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction Active AU2014243418B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014243418A AU2014243418B2 (en) 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10161685.2 2010-04-30
AU2011247563A AU2011247563B2 (en) 2010-04-30 2011-04-29 Modified binding proteins inhibiting the VEGF-A receptor interaction
AU2014243418A AU2014243418B2 (en) 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2011247563A Division AU2011247563B2 (en) 2010-04-30 2011-04-29 Modified binding proteins inhibiting the VEGF-A receptor interaction

Publications (2)

Publication Number Publication Date
AU2014243418A1 AU2014243418A1 (en) 2014-10-30
AU2014243418B2 true AU2014243418B2 (en) 2016-09-22

Family

ID=51797615

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014243418A Active AU2014243418B2 (en) 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction

Country Status (1)

Country Link
AU (1) AU2014243418B2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010060748A1 (en) * 2008-11-03 2010-06-03 Molecular Partners Ag Binding proteins inhibiting the vegf-a receptor interaction

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010060748A1 (en) * 2008-11-03 2010-06-03 Molecular Partners Ag Binding proteins inhibiting the vegf-a receptor interaction

Also Published As

Publication number Publication date
AU2014243418A1 (en) 2014-10-30

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