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AU2014250643B2 - Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate - Google Patents
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AU2014250643B2 - Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate - Google Patents

Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate

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Publication number
AU2014250643B2
AU2014250643B2 AU2014250643A AU2014250643A AU2014250643B2 AU 2014250643 B2 AU2014250643 B2 AU 2014250643B2 AU 2014250643 A AU2014250643 A AU 2014250643A AU 2014250643 A AU2014250643 A AU 2014250643A AU 2014250643 B2 AU2014250643 B2 AU 2014250643B2
Authority
AU
Australia
Prior art keywords
liver function
restoration
treatment
portal hypertension
ornithine phenylacetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014250643A
Other versions
AU2014250643A1 (en
Inventor
Keith Anderson
Rajiv Jalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCL Business Ltd
Ocera Therapeutics Inc
Original Assignee
UCL Business Ltd
Ocera Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2010258888A external-priority patent/AU2010258888B2/en
Application filed by UCL Business Ltd, Ocera Therapeutics Inc filed Critical UCL Business Ltd
Priority to AU2014250643A priority Critical patent/AU2014250643B2/en
Publication of AU2014250643A1 publication Critical patent/AU2014250643A1/en
Application granted granted Critical
Publication of AU2014250643B2 publication Critical patent/AU2014250643B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

TREATMENT OF PORTAL HYPERTENSION AND RESTORATION OF LIVER FUNCTION USING L-ORNITHINE PHENYLACETATE Disclosed herein are methods of treating and/or preventing portal hypertension and/or restoring liver function using L-ornithine phenylacetate.
AU2014250643A 2009-06-08 2014-10-15 Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate Active AU2014250643B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014250643A AU2014250643B2 (en) 2009-06-08 2014-10-15 Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61/185,158 2009-06-08
US61/240,748 2009-09-09
US61/296,377 2010-01-19
AU2010258888A AU2010258888B2 (en) 2009-06-08 2010-06-08 Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate
AU2014250643A AU2014250643B2 (en) 2009-06-08 2014-10-15 Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2010258888A Division AU2010258888B2 (en) 2009-06-08 2010-06-08 Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate

Publications (2)

Publication Number Publication Date
AU2014250643A1 AU2014250643A1 (en) 2014-11-06
AU2014250643B2 true AU2014250643B2 (en) 2016-07-14

Family

ID=51845146

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014250643A Active AU2014250643B2 (en) 2009-06-08 2014-10-15 Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate

Country Status (1)

Country Link
AU (1) AU2014250643B2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2153870T1 (en) 2004-11-26 2014-05-30 Ucl Business Plc Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
HUE035921T2 (en) 2009-04-03 2018-05-28 Ocera Therapeutics Inc L-Ornithine Phenylacetate and Methods of Preparation
CN104434894A (en) 2009-06-08 2015-03-25 Ucl商业有限公司 Reatment of portal hypertension using l-ornithine phenylacetate
ES2769000T3 (en) 2014-11-24 2020-06-24 Ucl Business Ltd Treatment of diseases associated with the activation of liver stellate cells using ammonia-reducing therapies
CN107708684A (en) * 2015-04-20 2018-02-16 欧塞拉治疗有限公司 L-ornithine phenylacetate preparation
WO2017031131A1 (en) 2015-08-18 2017-02-23 Ocera Therapeutics, Inc. Treatment and prevention of muscle loss using l-ornithine in combination with at least one of phenylacetate and phenylbutyrate
CN108366983A (en) 2015-11-13 2018-08-03 欧塞拉治疗有限公司 L-ornithine phenylacetate preparation
US11219611B2 (en) 2015-11-13 2022-01-11 Ocera Therapeutics, Inc. Formulations of L-ornithine phenylacetate
MX389665B (en) 2017-05-11 2025-03-20 Ocera Therapeutics Inc PROCESSES FOR PRODUCING L-ORNITHINE PHENYLACETATE

Also Published As

Publication number Publication date
AU2014250643A1 (en) 2014-11-06

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Legal Events

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FGA Letters patent sealed or granted (standard patent)