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AU2015200990B2 - Optimized Fc variants - Google Patents
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AU2015200990B2 - Optimized Fc variants - Google Patents

Optimized Fc variants

Info

Publication number
AU2015200990B2
AU2015200990B2 AU2015200990A AU2015200990A AU2015200990B2 AU 2015200990 B2 AU2015200990 B2 AU 2015200990B2 AU 2015200990 A AU2015200990 A AU 2015200990A AU 2015200990 A AU2015200990 A AU 2015200990A AU 2015200990 B2 AU2015200990 B2 AU 2015200990B2
Authority
AU
Australia
Prior art keywords
variants
optimized
region
parent polypeptide
variant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2015200990A
Other versions
AU2015200990A1 (en
Inventor
Christian Behrens
Khalil Bouayadi
Sylvie Jorieux
Abdelhakim Kharrat
Philippe Mondon
Celine Monnet-Mars
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LFB SA
Original Assignee
LFB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2010224800A external-priority patent/AU2010224800B2/en
Application filed by LFB SA filed Critical LFB SA
Priority to AU2015200990A priority Critical patent/AU2015200990B2/en
Publication of AU2015200990A1 publication Critical patent/AU2015200990A1/en
Application granted granted Critical
Publication of AU2015200990B2 publication Critical patent/AU2015200990B2/en
Priority to AU2016213792A priority patent/AU2016213792B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to a variant of a parent polypeptide comprising an Fc region. The said variant exhibits increased binding to FcRn as compared to the parent polypeptide and comprises at least one amino acid modification in its Fc region.
AU2015200990A 2009-03-20 2015-02-26 Optimized Fc variants Active AU2015200990B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2015200990A AU2015200990B2 (en) 2009-03-20 2015-02-26 Optimized Fc variants
AU2016213792A AU2016213792B2 (en) 2009-03-20 2016-08-11 Optimized Fc variants

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09305250.4 2009-03-20
AU2010224800A AU2010224800B2 (en) 2009-03-20 2010-03-19 Optimized Fc variants
AU2015200990A AU2015200990B2 (en) 2009-03-20 2015-02-26 Optimized Fc variants

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2010224800A Division AU2010224800B2 (en) 2009-03-20 2010-03-19 Optimized Fc variants

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016213792A Division AU2016213792B2 (en) 2009-03-20 2016-08-11 Optimized Fc variants

Publications (2)

Publication Number Publication Date
AU2015200990A1 AU2015200990A1 (en) 2015-03-19
AU2015200990B2 true AU2015200990B2 (en) 2016-07-21

Family

ID=52672553

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015200990A Active AU2015200990B2 (en) 2009-03-20 2015-02-26 Optimized Fc variants

Country Status (1)

Country Link
AU (1) AU2015200990B2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20260151T1 (en) 2016-08-02 2026-03-27 Visterra, Inc. MODIFIED POLYPEPTIDES AND THEIR USE
EP3576793A4 (en) * 2017-02-06 2021-03-31 Dana Farber Cancer Institute, Inc. COMPOSITIONS AND METHODS FOR INCREASING RECEPTOR SIGNALING MEDIA BY ANTIBODIES
CN112236448B (en) * 2018-04-17 2025-02-11 海德堡生物技术有限公司 Means and methods for treating angiogenesis, fibrosis and cancer-related diseases using protein oligomers containing NC-1-Fc
CN114096559B (en) * 2019-03-27 2026-03-20 蒂嘉特克斯公司 Engineered IGA antibodies and their usage

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090041770A1 (en) * 2004-11-12 2009-02-12 Chamberlain Aaron Keith Fc VARIANTS WITH ALTERED BINDING TO FcRn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090041770A1 (en) * 2004-11-12 2009-02-12 Chamberlain Aaron Keith Fc VARIANTS WITH ALTERED BINDING TO FcRn

Also Published As

Publication number Publication date
AU2015200990A1 (en) 2015-03-19

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FGA Letters patent sealed or granted (standard patent)