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AU468637B2 - Multisensor particle sorter - Google Patents
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AU468637B2 - Multisensor particle sorter - Google Patents

Multisensor particle sorter

Info

Publication number
AU468637B2
AU468637B2 AU50202/72A AU5020272A AU468637B2 AU 468637 B2 AU468637 B2 AU 468637B2 AU 50202/72 A AU50202/72 A AU 50202/72A AU 5020272 A AU5020272 A AU 5020272A AU 468637 B2 AU468637 B2 AU 468637B2
Authority
AU
Australia
Prior art keywords
multisensor
particle sorter
sorter
particle
multisensor particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU50202/72A
Other versions
AU5020272A (en
Inventor
JOHN A. STEINKAMP and JAMES R. COULTER MACK. J. FULWILER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Energy
Original Assignee
US Department of Energy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Energy filed Critical US Department of Energy
Application granted granted Critical
Publication of AU468637B2 publication Critical patent/AU468637B2/en
Publication of AU5020272A publication Critical patent/AU5020272A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1024—Counting particles by non-optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1028—Sorting particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/103—Particle shape
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1406—Control of droplet point
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AU50202/72A 1971-12-23 1972-12-18 Multisensor particle sorter Expired AU468637B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21147371A 1971-12-23 1971-12-23
USUS211,473 1971-12-23

Publications (2)

Publication Number Publication Date
AU468637B2 true AU468637B2 (en) 1974-06-20
AU5020272A AU5020272A (en) 1974-06-20

Family

ID=22787055

Family Applications (1)

Application Number Title Priority Date Filing Date
AU50202/72A Expired AU468637B2 (en) 1971-12-23 1972-12-18 Multisensor particle sorter

Country Status (11)

Country Link
US (1) US3710933A (en)
JP (1) JPS5613266B2 (en)
AU (1) AU468637B2 (en)
BE (1) BE793185A (en)
CA (1) CA971913A (en)
DE (1) DE2261695C2 (en)
FR (1) FR2164898B1 (en)
GB (1) GB1380756A (en)
NL (1) NL7216901A (en)
NO (1) NO138305C (en)
SE (1) SE388278B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU578622B2 (en) * 1983-10-31 1988-11-03 Technicon Instruments Corportion Method and apparatus for determining the volume and index of refraction of particles

Families Citing this family (231)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3819270A (en) * 1972-10-02 1974-06-25 Block Engineering Blood cell analyzer
US3791517A (en) * 1973-03-05 1974-02-12 Bio Physics Systems Inc Digital fluidic amplifier particle sorter
US3984307A (en) * 1973-03-05 1976-10-05 Bio/Physics Systems, Inc. Combined particle sorter and segregation indicator
US3827555A (en) * 1973-03-05 1974-08-06 Bio Physics Systems Inc Particle sorter with segregation indicator
US3907437A (en) * 1973-04-26 1975-09-23 Block Engineering Cell classification system
US3824402A (en) * 1973-06-04 1974-07-16 Energy Commission Dual parameter flow photometric apparatus and method
US4009435A (en) * 1973-10-19 1977-02-22 Coulter Electronics, Inc. Apparatus for preservation and identification of particles analyzed by flow-through apparatus
US3924947A (en) * 1973-10-19 1975-12-09 Coulter Electronics Apparatus for preservation and identification of particles analyzed by flow-through apparatus
US4074939A (en) * 1973-12-19 1978-02-21 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Apparatus for investigating fast chemical reactions by optical detection
US3910702A (en) * 1974-02-12 1975-10-07 Particle Technology Inc Apparatus for detecting particles employing apertured light emitting device
US3963606A (en) * 1974-06-03 1976-06-15 Coulter Electronics, Inc. Semi-automatic adjusting delay for an electronic particle separator
US4071298A (en) * 1974-06-27 1978-01-31 Stanford Research Institute Laser Raman/fluorescent device for analyzing airborne particles
DE2543310C2 (en) * 1975-09-27 1982-04-29 Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München Device for counting and classifying particles suspended in a liquid
FR2328960A1 (en) * 1975-10-08 1977-05-20 Coulter Electronics DEVICE FOR PRESERVATION AND IDENTIFICATION OF PARTICLES ANALYZED BY A THROUGH-FLOW DEVICE
US4053229A (en) * 1976-01-13 1977-10-11 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration 2°/90° Laboratory scattering photometer
SE400841B (en) * 1976-02-05 1978-04-10 Hertz Carl H WAY TO CREATE A LIQUID RAY AND DEVICE FOR IMPLEMENTING THE SET
US4162282A (en) * 1976-04-22 1979-07-24 Coulter Electronics, Inc. Method for producing uniform particles
US4101276A (en) * 1976-06-02 1978-07-18 Beckman Instruments, Inc. Method and apparatus for signalling the introduction of chemical reaction components into a chemical analyzing system
GB1563856A (en) * 1976-06-10 1980-04-02 Coulter Electronics Methods and apparatus for delectively separating small particles suspended in a liquid
US4095898A (en) * 1976-06-10 1978-06-20 Coulter Electronics, Inc. Particle analysis system with photochromic filter
NL180704C (en) * 1976-06-14 Coulter Electronics DEVICE FOR SIMULTANEOUS OPTICAL MEASUREMENT OF CHARACTERISTICS OF PARTICLES CONTAINING IN SUSPENSION.
DE2632962C3 (en) * 1976-07-22 1980-08-21 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Particle separator
DE2742838A1 (en) * 1977-09-23 1979-04-05 Zoeld Tibor Dr Phys Counting and size determination of particles in electrolyte - using electrodes designed to absorb electrolytically produced gas molecules on electrode surfaces
DE2712360A1 (en) * 1977-03-22 1978-09-28 Zoeld Tibor Dr Phys Counter and sizing appts. for suspended particles - has narrow aperture outlet and electrodes positioned outside flow path
US4097373A (en) * 1977-03-23 1978-06-27 John Caldwell Allred High speed particle sorter using a field emission electrode
US4203670A (en) * 1977-04-21 1980-05-20 Bromberg Nathan S System and method of fluorescence polarimetry
US4191739A (en) * 1977-10-17 1980-03-04 General Electric Company Antigen-antibody reaction assay employing particle aggregation and resistive pulse analysis
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
US4230031A (en) * 1978-04-26 1980-10-28 Coulter Electronics, Inc. Biohazard containment apparatus and method
FR2431694A1 (en) * 1978-07-18 1980-02-15 Berber Viktor Granulometric analysis of particles in fluids - by detecting reflected light following passage through nozzle
US4577964A (en) * 1978-09-06 1986-03-25 Ortho Diagnostics, Inc. Apparatus and method for detecting platelets in whole blood
US4293221A (en) * 1979-04-17 1981-10-06 Research Corporation Multidimensional slit-scan flow system
US4263508A (en) * 1979-04-20 1981-04-21 Research Corporation Pulse edge measurement for determining particle dimensional characteristics
US4347935A (en) * 1979-05-16 1982-09-07 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for electrostatically sorting biological cells
US4279345A (en) * 1979-08-03 1981-07-21 Allred John C High speed particle sorter using a field emission electrode
US4318480A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device
US4318483A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Automatic relative droplet charging time delay system for an electrostatic particle sorting system using a relatively moveable stream surface sensing system
US4318482A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method for measuring the velocity of a perturbed jetting fluid in an electrostatic particle sorting system
US4325483A (en) * 1979-08-20 1982-04-20 Ortho Diagnostics, Inc. Method for detecting and controlling flow rates of the droplet forming stream of an electrostatic particle sorting apparatus
US4317520A (en) * 1979-08-20 1982-03-02 Ortho Diagnostics, Inc. Servo system to control the spatial position of droplet formation of a fluid jet in a cell sorting apparatus
US4318481A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method for automatically setting the correct phase of the charge pulses in an electrostatic flow sorter
US4298836A (en) * 1979-11-23 1981-11-03 Coulter Electronics, Inc. Particle shape determination
NO145176C (en) 1979-11-23 1982-01-27 Norsk Hydros Inst For Kreftfor DEVICE OF FLUID FLOW PHOTOMETER.
US4284496A (en) * 1979-12-10 1981-08-18 Newton William A Particle guiding apparatus and method
US4284495A (en) * 1979-12-10 1981-08-18 Newton William A Coating apparatus and method
US4329787A (en) * 1980-01-04 1982-05-18 Newton William A Droplet exploding and freezing apparatus and method
US4350892A (en) * 1980-07-31 1982-09-21 Research Corporation X'-, Y'-, Z'- axis multidimensional slit-scan flow system
US4487320A (en) * 1980-11-03 1984-12-11 Coulter Corporation Method of and apparatus for detecting change in the breakoff point in a droplet generation system
US4352731A (en) * 1980-11-03 1982-10-05 Occidental Research Corporation Apparatus for selective wetting of particles
US4691829A (en) * 1980-11-03 1987-09-08 Coulter Corporation Method of and apparatus for detecting change in the breakoff point in a droplet generation system
US4395676A (en) * 1980-11-24 1983-07-26 Coulter Electronics, Inc. Focused aperture module
US4401755A (en) * 1981-01-29 1983-08-30 Massachusetts Institute Of Technology Process for measuring microbiologically active material
US4399219A (en) * 1981-01-29 1983-08-16 Massachusetts Institute Of Technology Process for isolating microbiologically active material
US4818103A (en) * 1981-05-15 1989-04-04 Ratcom Flow cytometry
US4673288A (en) * 1981-05-15 1987-06-16 Ratcom, Inc. Flow cytometry
US4667830A (en) * 1981-06-15 1987-05-26 The Board Of Trustees Of The Leland Stanford Junior University Method and means for sorting individual particles into containers for culturing, cloning, analysis, or the like
EP0068404B1 (en) * 1981-06-24 1985-10-02 Becton Dickinson and Company Analyzer for simultaneously determining volume and light emission characteristics of particles
US4476231A (en) * 1981-07-22 1984-10-09 International Remote Imaging Systems, Inc. Method of analyzing the distribution of a reagent between particles and liquid in a suspension
JPS5821166A (en) * 1981-07-30 1983-02-07 Fujitsu Ltd Separation of material to be measured
US4444317A (en) * 1981-08-26 1984-04-24 Georg Wick Observation of immunofluorescene for distinguishing between specific and nonspecific binding of conjugates
JPS5847239A (en) * 1981-09-14 1983-03-18 Nisshin Denki Seisakusho:Kk Liquid chromatograph apparatus
US4515274A (en) * 1981-12-02 1985-05-07 Coulter Corporation Particle analyzing and sorting apparatus
US4510438A (en) * 1982-02-16 1985-04-09 Coulter Electronics, Inc. Coincidence correction in particle analysis system
US4498766A (en) * 1982-03-25 1985-02-12 Becton, Dickinson And Company Light beam focal spot elongation in flow cytometry devices
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
DE3233055C2 (en) * 1982-09-06 1994-07-28 Coulter Electronics Flow device for examining individual particles suspended in a liquid
DE3238353A1 (en) * 1982-10-15 1984-04-19 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen METHOD FOR SIMULTANEOUSLY QUANTITATIVE DETERMINATION OF BLOOD CELLS AND REAGENT THEREFOR
JPS5995440A (en) * 1982-11-25 1984-06-01 Eisai Co Ltd Method and device for optical measurement
CA1206559A (en) * 1983-03-04 1986-06-24 Robert E. Auer Method of and apparatus for detecting change in the breakoff point of a droplet generation system
US4521521A (en) * 1983-03-11 1985-06-04 E. I. Du Pont De Nemours And Company Particle reagent size distribution measurements for immunoassay
CH651930A5 (en) * 1983-03-24 1985-10-15 Coulter Corp Apparatus for analysis and sorting of particles
JPS59174742A (en) * 1983-03-25 1984-10-03 Agency Of Ind Science & Technol Method and apparatus for dividing and sorting fine particle
JPS59184841A (en) * 1983-04-05 1984-10-20 ベクトン・デイツキンソン・アンド・カンパニ− Method and device for discriminating sub-class of leukocyte in sample
JPS59167065U (en) * 1983-04-25 1984-11-08 日産ディーゼル工業株式会社 Fully hydraulic power steering system
US4564803A (en) * 1983-08-29 1986-01-14 Coulter Corporation Method and apparatus for removing foreign matter from a flow cell of a particle study device
JPS6080764A (en) * 1983-10-12 1985-05-08 Agency Of Ind Science & Technol Method and device for identifying microparticle
US4538733A (en) * 1983-10-14 1985-09-03 Becton, Dickinson And Company Particle sorter with neutralized collection wells and method of using same
JPS6078013U (en) * 1983-11-02 1985-05-31 三洋電機株式会社 LCD display substrate
JPS60100785U (en) * 1983-12-15 1985-07-09 シャープ株式会社 display device
US5188935A (en) * 1984-05-31 1993-02-23 Coulter Electronics, Inc. Reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
EP0177718B1 (en) * 1984-09-11 1989-12-06 Partec AG Method and device for sorting microscopic particles
US4661913A (en) * 1984-09-11 1987-04-28 Becton, Dickinson And Company Apparatus and method for the detection and classification of articles using flow cytometry techniques
US4916060A (en) * 1985-09-17 1990-04-10 Massachusetts Institute Of Technology Process for chemical measurement in small volume samples by fluorescent indicators
US4760328A (en) * 1986-05-05 1988-07-26 Integrated Ionics, Inc. Particle counter having electrodes and circuitry mounted on the pane of the orifice
ATE91789T1 (en) * 1987-02-17 1993-08-15 Ratcom Inc FLOW CYTOMETRY.
US4987539A (en) * 1987-08-05 1991-01-22 Stanford University Apparatus and method for multidimensional characterization of objects in real time
US4988619A (en) * 1987-11-30 1991-01-29 United States Department Of Energy Flow cytometry apparatus
US4837446A (en) * 1988-03-31 1989-06-06 International Paper Company Apparatus and process for testing uniformity of pulp
US4844610A (en) * 1988-04-29 1989-07-04 Becton, Dickinson And Company Backflow isolator and capture system
US5089384A (en) * 1988-11-04 1992-02-18 Amoco Corporation Method and apparatus for selective cell destruction using amplified immunofluorescence
CA1324894C (en) * 1989-03-31 1993-12-07 Maritime Scientific Services Ltd. Method and apparatus for the identification of particles
JPH02289808A (en) * 1989-04-28 1990-11-29 Olympus Optical Co Ltd Lighting optical system
GB2233759B (en) * 1989-06-12 1993-08-25 De Beers Ind Diamond Particulate ore sorting
US5030002A (en) * 1989-08-11 1991-07-09 Becton, Dickinson And Company Method and apparatus for sorting particles with a moving catcher tube
US5275787A (en) * 1989-10-04 1994-01-04 Canon Kabushiki Kaisha Apparatus for separating or measuring particles to be examined in a sample fluid
DE69025256T2 (en) * 1989-10-11 1996-06-27 Canon Kk Apparatus and method for separating particles from liquid suspended particles in connection with their properties
FR2653885B1 (en) * 1989-10-27 1994-01-14 Abx APPARATUS FOR COUNTING AND DETERMINING AT LEAST ONE LEUKOCYTAIC SUB-POPULATION.
US5194909A (en) * 1990-12-04 1993-03-16 Tycko Daniel H Apparatus and method for measuring volume and hemoglobin concentration of red blood cells
US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
JP2537764Y2 (en) * 1991-05-07 1997-06-04 日工株式会社 Pipe cutting device
US5558998A (en) * 1992-02-25 1996-09-24 The Regents Of The Univ. Of California DNA fragment sizing and sorting by laser-induced fluorescence
US5232828A (en) * 1992-03-09 1993-08-03 Becton, Dickinson And Company Coating agents for cell recovery
US5859705A (en) * 1993-05-26 1999-01-12 The Dow Chemical Company Apparatus and method for using light scattering to determine the size of particles virtually independent of refractive index
US5464581A (en) * 1993-08-02 1995-11-07 The Regents Of The University Of California Flow cytometer
US5540494A (en) * 1994-06-03 1996-07-30 Purvis, Jr.; Norman B. Method and apparatus for determining absolute particle size, surface area and volume normalized fluorescence using forward angle light scatter intensity in flow cytometry
DE69527585T2 (en) * 1994-06-08 2003-04-03 Affymetrix, Inc. Method and device for packaging chips
US6287850B1 (en) 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
US6121048A (en) * 1994-10-18 2000-09-19 Zaffaroni; Alejandro C. Method of conducting a plurality of reactions
US5641457A (en) * 1995-04-25 1997-06-24 Systemix Sterile flow cytometer and sorter with mechanical isolation between flow chamber and sterile enclosure
US6720149B1 (en) * 1995-06-07 2004-04-13 Affymetrix, Inc. Methods for concurrently processing multiple biological chip assays
US5649576A (en) * 1996-02-26 1997-07-22 Pharmacopeia, Inc. Partitioning device
US6145247A (en) 1996-06-27 2000-11-14 Weyerhaeuser Company Fluid switch
WO1998017383A1 (en) * 1996-10-21 1998-04-30 Smithkline Beecham Plc Apparatus and method for distributing beads
DE19700648A1 (en) * 1997-01-10 1998-07-23 Basf Ag Method and device for determining the size distribution of different types of particles in a sample
EP2264427B1 (en) 1997-01-31 2017-05-03 Xy, Llc Optical apparatus with focussing reflector for converging radiation onto a flow of particles, and related method of analysis
US6149867A (en) * 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6071689A (en) * 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6265163B1 (en) 1998-01-09 2001-07-24 Lynx Therapeutics, Inc. Solid phase selection of differentially expressed genes
US6211477B1 (en) * 1998-02-26 2001-04-03 Becton Dickinson And Company Electrostatic deceleration system for flow cytometer
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
US6079836A (en) * 1998-07-20 2000-06-27 Coulter International Corp. Flow cytometer droplet break-off location adjustment mechanism
PT1917974E (en) 1998-07-30 2011-02-22 Xy Llc Equine system for non-surgical artificial insemination
US7510841B2 (en) * 1998-12-28 2009-03-31 Illumina, Inc. Methods of making and using composite arrays for the detection of a plurality of target analytes
US8148110B2 (en) * 1999-03-15 2012-04-03 The Board Of Trustees Of The Leland Stanford Junior University Detection of molecular interactions by β-lactamase reporter fragment complementation
US7097973B1 (en) * 1999-06-14 2006-08-29 Alpha Mos Method for monitoring molecular species within a medium
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
IL152714A (en) 2000-05-09 2014-03-31 Xy Llc High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
CN1633259A (en) * 2000-06-12 2005-06-29 Xy公司 Integrated herd management system utilizing isolated populations of X-chromosome bearing and Y-chromosome bearing spermatozoa
US6455007B1 (en) * 2000-06-13 2002-09-24 Symyx Technologies, Inc. Apparatus and method for testing compositions in contact with a porous medium
US20040031071A1 (en) * 2000-10-05 2004-02-12 Xy, Inc. System of hysteroscopic insemination of mares
US6849423B2 (en) * 2000-11-29 2005-02-01 Picoliter Inc Focused acoustics for detection and sorting of fluid volumes
US20020064809A1 (en) 2000-11-29 2002-05-30 Mutz Mitchell W. Focused acoustic ejection cell sorting system and method
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002043486A1 (en) 2000-11-29 2002-06-06 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US20040171163A1 (en) * 2000-12-15 2004-09-02 Lopez Peter A. Electrical conductive containment system
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
CA2442282A1 (en) * 2001-03-29 2002-10-10 Cellect Technologies Corp. Methods devices and systems for sorting and separating particles
EP1395374B1 (en) 2001-05-17 2013-04-17 Beckman Coulter, Inc. Flow cytometer with active automated optical alignment system
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
AUPR846501A0 (en) * 2001-10-26 2001-11-15 Btf Pty Ltd A cytometer
ATE443252T1 (en) * 2001-11-30 2009-10-15 Sysmex Corp PARTICLE ANALYZER
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
JP4595067B2 (en) 2002-08-01 2010-12-08 エックスワイ，エルエルシー Low-pressure sperm cell separation system
CA2534394C (en) * 2002-08-15 2013-01-08 Xy, Inc. High resolution flow cytometer
US7169548B2 (en) * 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
JP4050748B2 (en) * 2002-09-27 2008-02-20 リオン株式会社 Particle measuring device
US7201875B2 (en) * 2002-09-27 2007-04-10 Becton Dickinson And Company Fixed mounted sorting cuvette with user replaceable nozzle
US6941005B2 (en) * 2002-11-01 2005-09-06 Coulter International Corp. Monitoring and control of droplet sorting
US20040110241A1 (en) * 2002-12-06 2004-06-10 Segal Mark S. Materials and methods for monitoring vascular endothelial function
BRPI0408857B1 (en) 2003-03-28 2018-09-11 Inguran Llc apparatus, methods and processes for separating particles and for providing sex-separated animal sperm
ES2541121T3 (en) 2003-05-15 2015-07-16 Xy, Llc Efficient classification of haploid cells by flow cytometry systems
US20040241659A1 (en) * 2003-05-30 2004-12-02 Applera Corporation Apparatus and method for hybridization and SPR detection
US8049888B2 (en) * 2004-03-01 2011-11-01 Firma Cytecs Gmbh Device for measuring light emitted by microscopically small particles or biological cells
DK2801363T3 (en) 2004-03-29 2018-05-28 Inguran Llc PROCEDURE FOR STORING SORTED SPERMATOZOES
CA2574499C (en) 2004-07-22 2016-11-29 Monsanto Technology Llc Process for enriching a population of sperm cells
DK1771729T3 (en) * 2004-07-27 2015-11-23 Beckman Coulter Inc Improving flowcytometridiskrimination using geometric transformation
CN100595564C (en) 2004-07-30 2010-03-24 百维吉伦特系统有限公司 Pathogen and particle detector systems and methods
US7392908B2 (en) * 2005-01-12 2008-07-01 Beckman Coulter, Inc. Methods and apparatus for sorting particles hydraulically
US20060246576A1 (en) * 2005-04-06 2006-11-02 Affymetrix, Inc. Fluidic system and method for processing biological microarrays in personal instrumentation
US20060284930A1 (en) * 2005-06-21 2006-12-21 George Mejalli Methods and arrangements for adjusting and aligning fluid dispensing devices and the like such as continuous ink jet printheads
EP1907818A4 (en) * 2005-07-15 2012-03-14 Biovigilant Systems Inc Pathogen and particle detector system and method
US7618770B2 (en) * 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US20070059370A1 (en) * 2005-09-15 2007-03-15 Industrial Technology Research Institute Method and apparatus for fabricating nanoparticles
US8297959B2 (en) * 2006-05-03 2012-10-30 Terapia Celular, Ln, Inc. Systems for producing multilayered particles, fibers and sprays and methods for administering the same
US20080003667A1 (en) * 2006-05-19 2008-01-03 Affymetrix, Inc. Consumable elements for use with fluid processing and detection systems
BRPI0719719A2 (en) * 2006-12-04 2014-02-18 Univ Queensland PARTICULAR CLASSIFICATION APPARATUS AND METHOD
GB0720202D0 (en) 2007-10-16 2007-11-28 Cambridge Entpr Ltd Microfluidic systems
US9267918B2 (en) 2007-10-16 2016-02-23 Cambridge Enterprise Limited Microfluidic systems
US8628976B2 (en) * 2007-12-03 2014-01-14 Azbil BioVigilant, Inc. Method for the detection of biologic particle contamination
FR2933192B1 (en) * 2008-06-25 2010-09-17 Horiba Abx Sas DEVICE AND METHOD FOR ELECTRO OPTICAL MEASUREMENT FOR CLASSIFYING AND COUNTING MICROSCOPIC ELEMENTS.
UA102854C2 (en) 2008-06-30 2013-08-27 Микробикс Байосистемз Инк. Method and device for sorting of cells
JP5382852B2 (en) 2009-02-06 2014-01-08 株式会社オンチップ・バイオテクノロジーズ Disposable chip type flow cell and flow cytometer using the same
JP5487638B2 (en) * 2009-02-17 2014-05-07 ソニー株式会社 Apparatus for microparticle sorting and microchip
US8665439B2 (en) * 2009-06-30 2014-03-04 Microbix Biosystems, Inc. Method and apparatus for limiting effects of refraction in cytometry
AT508806B1 (en) * 2009-10-07 2013-06-15 Onkotec Gmbh ANALYZER AND METHOD
US8589851B2 (en) * 2009-12-15 2013-11-19 Memoir Systems, Inc. Intelligent memory system compiler
WO2011077765A1 (en) * 2009-12-25 2011-06-30 古河電気工業株式会社 Sample identification and separation device, and sample identification and separation method
US10101261B2 (en) 2010-01-15 2018-10-16 On-Chip Biotechnologies Co., Ltd. Disposable chip-type flow cell and cell sorter using the same
WO2012055048A1 (en) * 2010-10-29 2012-05-03 The University Of British Columbia Methods and apparatus for detecting particles entrained in fluids
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
WO2012092259A1 (en) 2010-12-27 2012-07-05 Ibis Biosciences, Inc. Quantitating high titer samples by digital pcr
FR2970334A1 (en) * 2011-01-07 2012-07-13 Horiba Abx Sas DEVICE FOR INSPECTING A BIOLOGICAL FLUID
FR2971337B1 (en) * 2011-02-04 2013-03-01 Horiba Abx Sas DEVICE AND METHOD FOR MULTIPARAMETRIC MEASUREMENTS OF MICROPARTICLES IN A FLUID
MX338778B (en) 2011-02-15 2016-05-02 Microbix Biosystems Inc Methods, systems, and apparatus for performing flow cytometry.
US10723497B2 (en) * 2014-11-03 2020-07-28 Vanrx Pharmasystems Inc. Apparatus and method for monitoring and controlling the filling of a container with a pharmaceutical fluid in an aseptic environment
US9242248B2 (en) * 2011-09-16 2016-01-26 The University Of North Carolina At Charlotte Methods and devices for optical sorting of microspheres based on their resonant optical properties
US9841367B2 (en) 2011-09-16 2017-12-12 The University Of North Carolina At Charlotte Methods and devices for optical sorting of microspheres based on their resonant optical properties
WO2013096137A1 (en) 2011-12-20 2013-06-27 Becton, Dickinson And Company System and method to improve yield of sorted particles
WO2013101741A1 (en) 2011-12-30 2013-07-04 Abbott Molecular, Inc. Channels with cross-sectional thermal gradients
JP5924077B2 (en) 2012-03-30 2016-05-25 ソニー株式会社 Fine particle sorting device and method for determining orbit direction in fine particle sorting device
WO2013145905A1 (en) 2012-03-30 2013-10-03 ソニー株式会社 Microparticle fractionation apparatus, and method for optimizing fluid stream in said apparatus
JP6065527B2 (en) * 2012-11-08 2017-01-25 ソニー株式会社 Fine particle sorting device and fine particle sorting method
WO2014115409A1 (en) 2013-01-28 2014-07-31 ソニー株式会社 Fine particle fractionation device, fine particle fractionation method and program
JP2014174139A (en) * 2013-03-13 2014-09-22 Sony Corp Flow channel device, particle sorter, particle outflow method, and particle sorting method
US10983040B2 (en) 2013-03-15 2021-04-20 Particles Plus, Inc. Particle counter with integrated bootloader
US10352844B2 (en) 2013-03-15 2019-07-16 Particles Plus, Inc. Multiple particle sensors in a particle counter
US11579072B2 (en) 2013-03-15 2023-02-14 Particles Plus, Inc. Personal air quality monitoring system
US12044611B2 (en) 2013-03-15 2024-07-23 Particles Plus, Inc. Particle counter with integrated bootloader
US9677990B2 (en) 2014-04-30 2017-06-13 Particles Plus, Inc. Particle counter with advanced features
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
CN104297213B (en) * 2013-07-16 2017-10-03 成都深迈瑞医疗电子技术研究院有限公司 Blood cell analyzer and method and system for identifying abnormal cells
EP3035030B1 (en) 2013-10-16 2019-07-10 Sony Corporation Particle fractionation device, particle fractionation method, and program
JP6136843B2 (en) 2013-10-17 2017-05-31 ソニー株式会社 Particle sorting apparatus, particle sorting method and program
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
JP6733909B2 (en) 2013-10-30 2020-08-05 エービーエス グローバル インコーポレイテッド Device for identifying multiple substances, computer system for identifying multiple substances, program for causing a computer to execute multiple instructions for identifying multiple substances, and method for identifying multiple substances flowing in a sample fluid mixture
JP6465036B2 (en) 2014-02-13 2019-02-06 ソニー株式会社 Particle sorting device, particle sorting method, program, and particle sorting system
US8820538B1 (en) 2014-03-17 2014-09-02 Namocell LLC Method and apparatus for particle sorting
FR3022998B1 (en) * 2014-06-30 2016-07-15 Alain Rousseau Techniques & Innovations Arteion SYSTEM AND ASSEMBLY FOR FLOW CYTOMETRY, ANALYSIS DEVICE COMPRISING SUCH A CYTOMETRY ASSEMBLY AND ASSEMBLY COMPRISING SUCH A CYTOMETRY SYSTEM
JP6657625B2 (en) 2014-09-05 2020-03-04 ソニー株式会社 Droplet sorting apparatus, drop sorting method and program
EP3943912B1 (en) * 2015-02-12 2025-08-20 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Cell analyzer and particle sorting method and device
US10180388B2 (en) 2015-02-19 2019-01-15 1087 Systems, Inc. Scanning infrared measurement system
CN107532990B (en) * 2015-05-12 2021-11-12 芯片生物技术株式会社 Single particle analysis method and system for the same
WO2017068822A1 (en) 2015-10-19 2017-04-27 ソニー株式会社 Image processing device, microparticle separation device, and image processing method
DE102016115891A1 (en) * 2016-08-26 2018-03-01 Krones Aktiengesellschaft Filling plant for filling a container with a filling product
JP7020689B2 (en) 2016-09-16 2022-02-16 株式会社オンチップ・バイオテクノロジーズ Particle dispensing device, particle analysis device, reaction detection device, and method using them
US10466158B2 (en) * 2017-04-11 2019-11-05 Sony Corporation Microparticle sorting apparatus and delay time determination method
US11331670B2 (en) 2018-05-23 2022-05-17 Abs Global, Inc. Systems and methods for particle focusing in microchannels
EP3899489B1 (en) 2018-12-21 2025-04-09 ABS Global, Inc. System and methods for sub-population identification
EP3955735B1 (en) 2019-04-18 2024-05-22 ABS Global, Inc. System and process for continuous addition of cryoprotectant
US11307132B2 (en) * 2019-06-26 2022-04-19 Life Technologies Corporation Integrated biocontainment cell sorter
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip
US20230256440A1 (en) * 2020-06-26 2023-08-17 Hewlett-Packard Development Company, L.P. Target particle ejection from recirculating fluid ejection channels
US11988591B2 (en) 2020-07-01 2024-05-21 Particles Plus, Inc. Modular optical particle counter sensor and apparatus
WO2022087299A1 (en) 2020-10-21 2022-04-28 Abs Global, Inc. Methods and systems for processing genetic samples to determine identity or detect contamination
US12135270B2 (en) 2020-11-23 2024-11-05 Abs Global, Inc. Modular flow cytometry systems and methods of processing samples
USD1118965S1 (en) 2021-11-12 2026-03-17 Abs Global, Inc. Flow cytometry device
CN119915706B (en) * 2025-04-07 2025-06-27 四川大学华西医院 Data processing method and system applied to flow cytometer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3380584A (en) * 1965-06-04 1968-04-30 Atomic Energy Commission Usa Particle separator
US3560754A (en) * 1965-11-17 1971-02-02 Ibm Photoelectric particle separator using time delay
US3497690A (en) * 1967-09-21 1970-02-24 Bausch & Lomb Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof
US3675768A (en) * 1969-03-17 1972-07-11 Gildardo Legorreta Sanchez Method and apparatus for classifying and segregating particles with electrical and optical means

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU578622B2 (en) * 1983-10-31 1988-11-03 Technicon Instruments Corportion Method and apparatus for determining the volume and index of refraction of particles

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JPS4874292A (en) 1973-10-06
SE388278B (en) 1976-09-27
AU5020272A (en) 1974-06-20
FR2164898A1 (en) 1973-08-03
US3710933A (en) 1973-01-16
BE793185A (en) 1973-04-16
DE2261695C2 (en) 1987-04-09
JPS5613266B2 (en) 1981-03-27
NL7216901A (en) 1973-06-26
DE2261695A1 (en) 1973-06-28
CA971913A (en) 1975-07-29
GB1380756A (en) 1975-01-15
NO138305C (en) 1978-08-09
FR2164898B1 (en) 1974-08-02

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