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AU512150B2 - Penicillin manufacture - Google Patents
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AU512150B2 - Penicillin manufacture - Google Patents

Penicillin manufacture

Info

Publication number
AU512150B2
AU512150B2 AU21340/77A AU2134077A AU512150B2 AU 512150 B2 AU512150 B2 AU 512150B2 AU 21340/77 A AU21340/77 A AU 21340/77A AU 2134077 A AU2134077 A AU 2134077A AU 512150 B2 AU512150 B2 AU 512150B2
Authority
AU
Australia
Prior art keywords
penicillin
manufacture
penicillin manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU21340/77A
Other versions
AU2134077A (en
Inventor
M. and Cotti G Groot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of AU2134077A publication Critical patent/AU2134077A/en
Application granted granted Critical
Publication of AU512150B2 publication Critical patent/AU512150B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04Preparation
    • C07D499/10Modification of an amino radical directly attached in position 6
    • C07D499/12Acylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
AU21340/77A 1976-01-15 1977-01-14 Penicillin manufacture Expired AU512150B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITIT47643A/7 1976-01-15
IT47643/76A IT1053313B (en) 1976-01-15 1976-01-15 PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS

Publications (2)

Publication Number Publication Date
AU2134077A AU2134077A (en) 1978-07-20
AU512150B2 true AU512150B2 (en) 1980-09-25

Family

ID=11261624

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21340/77A Expired AU512150B2 (en) 1976-01-15 1977-01-14 Penicillin manufacture

Country Status (14)

Country Link
JP (1) JPS5287191A (en)
AU (1) AU512150B2 (en)
BE (1) BE850382A (en)
CH (1) CH627182A5 (en)
DE (1) DE2701406A1 (en)
DK (1) DK13977A (en)
ES (1) ES455026A1 (en)
FR (1) FR2338279A1 (en)
GB (1) GB1569427A (en)
IT (1) IT1053313B (en)
NL (1) NL7700396A (en)
SE (1) SE437989B (en)
YU (1) YU9277A (en)
ZA (1) ZA77195B (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB958478A (en) * 1962-03-13 1964-05-21 Beecham Res Lab Production of penicillins
BE638819A (en) * 1962-10-17
US3351597A (en) * 1966-11-23 1967-11-07 Lilly Co Eli Process for acylating 7-amino cephalosporanic acid
ZA695612B (en) * 1968-08-23 1971-03-31 Lilly Co Eli Preparation of cephalosporin compounds
US3595855A (en) * 1968-12-05 1971-07-27 American Home Prod Process for producing aminopenicillins
IT1043957B (en) * 1970-12-31 1980-02-29 Lorenzini Sas Inst Biochim PROCESS FOR THE PREPARATION OF THE ANHYDROUS FORM OF ACID 6, D, LESS ALPINE AMINOPHENYLACETAMIDE PENICILLANIC
GB1494902A (en) * 1974-05-09 1977-12-14 Glaxo Lab Ltd Penicillins
IT1039495B (en) * 1975-06-26 1979-12-10 Dobfar Spa PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC SUBSTANCES

Also Published As

Publication number Publication date
ES455026A1 (en) 1977-12-16
CH627182A5 (en) 1981-12-31
FR2338279A1 (en) 1977-08-12
JPS5287191A (en) 1977-07-20
DK13977A (en) 1977-07-16
AU2134077A (en) 1978-07-20
DE2701406A1 (en) 1977-07-21
FR2338279B1 (en) 1980-09-05
BE850382A (en) 1977-07-14
NL7700396A (en) 1977-07-19
IT1053313B (en) 1981-08-31
SE437989B (en) 1985-03-25
YU9277A (en) 1982-06-30
GB1569427A (en) 1980-06-18
SE7700393L (en) 1977-07-16
ZA77195B (en) 1977-11-30

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