AU555093B2 - Calcium-antagonist composition - Google Patents
Calcium-antagonist compositionInfo
- Publication number
- AU555093B2 AU555093B2 AU82384/82A AU8238482A AU555093B2 AU 555093 B2 AU555093 B2 AU 555093B2 AU 82384/82 A AU82384/82 A AU 82384/82A AU 8238482 A AU8238482 A AU 8238482A AU 555093 B2 AU555093 B2 AU 555093B2
- Authority
- AU
- Australia
- Prior art keywords
- active compound
- calcium
- antagonistic
- antagonist composition
- sustaining dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
1. A pharmaceutical composition which contains a calcium-antagonistic active compound, with or without additional active compounds, is intended for oral administration to produce a sustained action for continuous therapy and contains only the sustaining dose of active compound, bound to pharmaceutical auxiliaries, wherein the calcium-antagonistic active compound is Gallopamil or Verapamil and wherein, at the sustaining dose, the ratio of the constituents with rapid release of active compound to those with sustained release of active compound is from 1 : 0.6 to 1 : 6.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813113901 DE3113901A1 (en) | 1981-04-07 | 1981-04-07 | ACTIVE SUBSTANCE PREPARATION FOR ORAL APPLICATION |
| DE31139019 | 1981-04-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU8238482A AU8238482A (en) | 1982-10-14 |
| AU555093B2 true AU555093B2 (en) | 1986-09-11 |
Family
ID=6129505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU82384/82A Ceased AU555093B2 (en) | 1981-04-07 | 1982-04-06 | Calcium-antagonist composition |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0063266B1 (en) |
| JP (1) | JPS57175113A (en) |
| AT (1) | ATE14076T1 (en) |
| AU (1) | AU555093B2 (en) |
| CA (1) | CA1184497A (en) |
| DE (2) | DE3113901A1 (en) |
| DK (1) | DK157482A (en) |
| ES (1) | ES8307496A1 (en) |
| FI (1) | FI821253L (en) |
| GR (1) | GR74770B (en) |
| HU (1) | HU186855B (en) |
| IE (1) | IE52985B1 (en) |
| IL (1) | IL65328A (en) |
| NO (1) | NO157204C (en) |
| NZ (1) | NZ200244A (en) |
| PT (1) | PT74705B (en) |
| ZA (1) | ZA822327B (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4461759A (en) * | 1983-01-03 | 1984-07-24 | Verex Laboratories, Inc. | Constant release rate solid oral dosage formulations of veropamil |
| US4874614A (en) * | 1985-03-25 | 1989-10-17 | Abbott Laboratories | Pharmaceutical tableting method |
| US4863741A (en) * | 1985-03-25 | 1989-09-05 | Abbott Laboratories | Tablet composition for drug combinations |
| LU86077A1 (en) * | 1985-09-18 | 1987-04-02 | Pharlyse Sa | NEW GALENIC FORMS OF VERAPAMIL, THEIR MANUFACTURE AND THE MEDICINAL PRODUCTS CONTAINING THESE NEW GALENIC FORMS |
| LU86099A1 (en) * | 1985-09-30 | 1987-04-02 | Pharlyse | EXTENDED RELEASE GALENIC FORMS OF VERAPAMIL, THEIR MANUFACTURE AND THE MEDICINAL PRODUCTS CONTAINING THEM |
| IE58401B1 (en) * | 1986-06-20 | 1993-09-08 | Elan Corp Plc | Controlled absorption pharmaceutical composition |
| US4981871A (en) * | 1987-05-15 | 1991-01-01 | Abelson Mark B | Treatment of ocular hypertension with class I calcium channel blocking agents |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| US5230901A (en) * | 1988-03-23 | 1993-07-27 | Knoll Ag | Sustained release tablet of a mixture of alginates and polyacrylates |
| DE3809764A1 (en) * | 1988-03-23 | 1989-10-05 | Knoll Ag | MIXTURE OF ALGINATES AND POLYACRYLATES AND THEIR USE |
| ES2045281T3 (en) * | 1988-07-13 | 1994-01-16 | Knoll Ag | MEDICATION FORM OF DELAYED ACTION ON THE BASIS OF ALGINATES. |
| US5032406A (en) * | 1989-02-21 | 1991-07-16 | Norwich Eaton Pharmaceuticals, Inc. | Dual-action tablet |
| DE3932378A1 (en) * | 1989-09-28 | 1991-04-11 | Knoll Ag | SOLID MEDICAL FORM WITH A HIGH VERAPAMIL CONTENT |
| IT1264696B1 (en) * | 1993-07-09 | 1996-10-04 | Applied Pharma Res | PHARMACEUTICAL FORMS INTENDED FOR ORAL ADMINISTRATION ABLE TO RELEASE ACTIVE SUBSTANCES AT A CONTROLLED AND DIFFERENTIATED SPEED |
| US5695781A (en) * | 1995-03-01 | 1997-12-09 | Hallmark Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers |
| US6083532A (en) | 1995-03-01 | 2000-07-04 | Duramed Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers and tablet formed therefrom |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1154810B (en) * | 1961-04-01 | 1963-09-26 | Knoll Ag | Process for the preparation of basic substituted phenylacetonitriles |
| DE1467781A1 (en) * | 1963-07-15 | 1968-12-05 | Boehringer Sohn Ingelheim | Process for the production of coated tablets with extended release of active ingredients |
-
1981
- 1981-04-07 DE DE19813113901 patent/DE3113901A1/en not_active Withdrawn
-
1982
- 1982-02-22 GR GR67376A patent/GR74770B/el unknown
- 1982-03-23 IL IL65328A patent/IL65328A/en unknown
- 1982-03-23 CA CA000399116A patent/CA1184497A/en not_active Expired
- 1982-03-31 DE DE8282102695T patent/DE3264519D1/en not_active Expired
- 1982-03-31 NO NO821084A patent/NO157204C/en unknown
- 1982-03-31 AT AT82102695T patent/ATE14076T1/en active
- 1982-03-31 EP EP82102695A patent/EP0063266B1/en not_active Expired
- 1982-04-01 JP JP57052378A patent/JPS57175113A/en active Pending
- 1982-04-05 PT PT74705A patent/PT74705B/en unknown
- 1982-04-05 ZA ZA822327A patent/ZA822327B/en unknown
- 1982-04-06 IE IE812/82A patent/IE52985B1/en unknown
- 1982-04-06 ES ES511208A patent/ES8307496A1/en not_active Expired
- 1982-04-06 NZ NZ200244A patent/NZ200244A/en unknown
- 1982-04-06 DK DK157482A patent/DK157482A/en not_active Application Discontinuation
- 1982-04-06 HU HU821058A patent/HU186855B/en not_active IP Right Cessation
- 1982-04-06 AU AU82384/82A patent/AU555093B2/en not_active Ceased
- 1982-04-07 FI FI821253A patent/FI821253L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU8238482A (en) | 1982-10-14 |
| JPS57175113A (en) | 1982-10-28 |
| IE52985B1 (en) | 1988-04-27 |
| PT74705B (en) | 1983-11-14 |
| ES511208A0 (en) | 1983-08-16 |
| IL65328A (en) | 1985-06-30 |
| ES8307496A1 (en) | 1983-08-16 |
| GR74770B (en) | 1984-07-12 |
| EP0063266A3 (en) | 1983-05-04 |
| HU186855B (en) | 1985-10-28 |
| DE3113901A1 (en) | 1982-10-28 |
| EP0063266B1 (en) | 1985-07-03 |
| NO821084L (en) | 1982-10-08 |
| NO157204C (en) | 1988-02-10 |
| ATE14076T1 (en) | 1985-07-15 |
| CA1184497A (en) | 1985-03-26 |
| FI821253A7 (en) | 1982-10-08 |
| NZ200244A (en) | 1984-08-24 |
| DE3264519D1 (en) | 1985-08-08 |
| PT74705A (en) | 1982-05-01 |
| EP0063266A2 (en) | 1982-10-27 |
| ZA822327B (en) | 1983-03-30 |
| FI821253A0 (en) | 1982-04-07 |
| IE820812L (en) | 1982-10-07 |
| DK157482A (en) | 1982-10-08 |
| FI821253L (en) | 1982-10-08 |
| IL65328A0 (en) | 1982-05-31 |
| NO157204B (en) | 1987-11-02 |
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