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AU555952B2 - Collagen implant containing active ingredient for implantation in bones - Google Patents
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AU555952B2 - Collagen implant containing active ingredient for implantation in bones - Google Patents

Collagen implant containing active ingredient for implantation in bones

Info

Publication number
AU555952B2
AU555952B2 AU85177/82A AU8517782A AU555952B2 AU 555952 B2 AU555952 B2 AU 555952B2 AU 85177/82 A AU85177/82 A AU 85177/82A AU 8517782 A AU8517782 A AU 8517782A AU 555952 B2 AU555952 B2 AU 555952B2
Authority
AU
Australia
Prior art keywords
active ingredient
bones
implantation
collagen
containing active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU85177/82A
Other versions
AU8517782A (en
Inventor
Karl Heinz Sorg
Wolfgang Steffan
Axel Stemberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU8517782A publication Critical patent/AU8517782A/en
Application granted granted Critical
Publication of AU555952B2 publication Critical patent/AU555952B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Collagen insert containing an active ingredient for introduction into bones or soft parts, characterized in that it is prepared by adding to a solution of high-purity native collagen, wherein the collagen has a factor of nitrogen to hydroxyproline =< 3 to 5, a solution or suspension of said active ingredient and then by drying with hot air or by freeze-drying a sheet is produced in the form of a fascia and finally it is optionally wound to form a rod.
AU85177/82A 1981-06-25 1982-06-24 Collagen implant containing active ingredient for implantation in bones Expired AU555952B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE31249817 1981-06-25
DE19813124981 DE3124981A1 (en) 1981-06-25 1981-06-25 ACTIVE INGREDIENT COLLAGEN INSERT FOR INSERTION INTO BONES OR SOFT PARTS AND METHOD FOR THEIR PRODUCTION

Publications (2)

Publication Number Publication Date
AU8517782A AU8517782A (en) 1983-01-06
AU555952B2 true AU555952B2 (en) 1986-10-16

Family

ID=6135358

Family Applications (1)

Application Number Title Priority Date Filing Date
AU85177/82A Expired AU555952B2 (en) 1981-06-25 1982-06-24 Collagen implant containing active ingredient for implantation in bones

Country Status (10)

Country Link
EP (1) EP0069260B1 (en)
JP (1) JPS584551A (en)
AT (1) ATE15763T1 (en)
AU (1) AU555952B2 (en)
CA (1) CA1183776A (en)
DE (2) DE3124981A1 (en)
IE (1) IE53579B1 (en)
MX (1) MX9203310A (en)
NZ (1) NZ201067A (en)
ZA (1) ZA824517B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409372A1 (en) * 1984-03-14 1985-09-19 Dr. Ruhland Nachf. GmbH, 8425 Neustadt Material for the vitalisation of implant surfaces
DE3500268A1 (en) * 1985-01-05 1986-07-10 Hoechst Ag, 6230 Frankfurt PREPARATIONS WITH DELAYED EFFECT, METHOD FOR THE PRODUCTION THEREOF AND CORRESPONDING AGENTS FOR THE HUMAN OR. VETERINE MEDICAL APPLICATION
DE3533369A1 (en) * 1985-09-19 1987-03-19 Alois Prof Dr Med Bloemer ANTIBIOTIC CONTAINER AND ITS USE AS SURGICAL PLASTIC MATERIAL
US4865602A (en) * 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
NL8701370A (en) * 1987-06-12 1987-08-03 Stichting Surgical Research Fo Chamois leather as an adhesive for living tissues.
AP105A (en) * 1987-12-11 1990-11-07 Geo Schwulst Laboratories Ltd Treatment of animals.
US5266683A (en) 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US4975526A (en) * 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US5162114A (en) * 1989-02-23 1992-11-10 Stryker Corporation Bone collagen matrix for xenogenic implants
US5354557A (en) * 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US6919308B2 (en) 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US5447966A (en) * 1988-07-19 1995-09-05 United States Surgical Corporation Treating bioabsorbable surgical articles by coating with glycerine, polalkyleneoxide block copolymer and gelatin
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
EP0475077B1 (en) * 1990-09-10 1996-06-12 Synthes AG, Chur Bone regeneration membrane
DE9203684U1 (en) * 1992-03-19 1992-07-02 Pohl, Yango, 61231 Bad Nauheim Device for root resection
IL105529A0 (en) * 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
US5733884A (en) 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
DE19739031A1 (en) * 1997-09-05 1999-03-11 Suwelack Nachf Dr Otto Oral administration agent, its preparation and use
DE19962248A1 (en) 1999-12-22 2001-06-28 Tutogen Medical Gmbh Producing bone material containing bone morphogenic protein, useful as transplant for accelerating bone growth, includes resorbable material for sustained release of protein
USRE47826E1 (en) 2007-03-28 2020-01-28 Innocoll Pharmaceuticals Limited Drug delivery device for providing local analgesia, local anesthesia or nerve blockage
US8034368B2 (en) 2007-03-28 2011-10-11 Innocoll Technologies Limited Drug delivery device for providing local analgesia, local anesthesia or nerve blockage
JP5945380B2 (en) * 2008-12-09 2016-07-05 Hoya株式会社 Absorption-replacement type artificial bone and manufacturing method thereof
FR2940620B1 (en) * 2008-12-26 2012-03-30 Hoya Corp ARTIFICIAL BONE THAT CAN BE REPLACED AND REPLACED BY AN AUTOGENOUS BONE AND METHOD FOR ITS PRODUCTION
EP2510929A1 (en) * 2011-04-11 2012-10-17 Innocoll Technologies Limited Methods for treating bacterial infection
EP2574349A1 (en) 2011-09-29 2013-04-03 Biorigen S.r.l Therapeutic use of gelatin hydrogels with a gel-sol transition at body temperature
WO2013045689A1 (en) 2011-09-29 2013-04-04 BIORIGEN Srl Therapeutic use of gelatin hydrogels with a gel-sol transition at body temperature

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3625214A (en) * 1970-05-18 1971-12-07 Alza Corp Drug-delivery device
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
CH627078A5 (en) * 1975-06-05 1981-12-31 Pentapharm Ag Process for the preparation of a sterile collagen product with felt-like or web-like fibre structure
JPS5842473B2 (en) * 1975-09-02 1983-09-20 シャープ株式会社 Hakumaku EL Soshino Kudohouhou
SU736374A1 (en) * 1977-06-06 1980-05-25 Предприятие П/Я Р-6517 Method and device for dc cutout
DE2815934A1 (en) * 1978-04-13 1979-10-25 Merck Patent Gmbh Surgical pegs for insertion into bone - consisting of a plastic and an antibacterial e.g. gentamycin
GB1565340A (en) * 1978-04-25 1980-04-16 Grant R A Fibrous tussue preparations
DE2854490C2 (en) * 1978-12-16 1981-04-09 B. Braun Melsungen Ag, 3508 Melsungen Bone substitute material with improved biological stability based on collagen
US4279812A (en) * 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen

Also Published As

Publication number Publication date
NZ201067A (en) 1985-05-31
IE821514L (en) 1982-12-25
JPS584551A (en) 1983-01-11
EP0069260A3 (en) 1983-06-22
EP0069260B1 (en) 1985-09-25
DE3266525D1 (en) 1985-10-31
AU8517782A (en) 1983-01-06
IE53579B1 (en) 1988-12-21
CA1183776A (en) 1985-03-12
DE3124981A1 (en) 1983-01-13
EP0069260A2 (en) 1983-01-12
ATE15763T1 (en) 1985-10-15
JPH0118744B2 (en) 1989-04-07
MX9203310A (en) 1992-07-01
ZA824517B (en) 1983-04-27

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired