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AU562964B2 - Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medical composition using a such platinum-diamine complex for the treatment of cancer, as well as the thus shaped composition - Google Patents
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AU562964B2 - Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medical composition using a such platinum-diamine complex for the treatment of cancer, as well as the thus shaped composition - Google Patents

Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medical composition using a such platinum-diamine complex for the treatment of cancer, as well as the thus shaped composition

Info

Publication number
AU562964B2
AU562964B2 AU20275/83A AU2027583A AU562964B2 AU 562964 B2 AU562964 B2 AU 562964B2 AU 20275/83 A AU20275/83 A AU 20275/83A AU 2027583 A AU2027583 A AU 2027583A AU 562964 B2 AU562964 B2 AU 562964B2
Authority
AU
Australia
Prior art keywords
platinum
preparation
diamine
composition
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU20275/83A
Other versions
AU2027583A (en
Inventor
Jan Berg
Eric Jan Bulten
Francois Verbeek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Original Assignee
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Publication of AU2027583A publication Critical patent/AU2027583A/en
Application granted granted Critical
Publication of AU562964B2 publication Critical patent/AU562964B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU20275/83A 1982-10-21 1983-10-18 Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medical composition using a such platinum-diamine complex for the treatment of cancer, as well as the thus shaped composition Ceased AU562964B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8204067 1982-10-21
NL8204067A NL8204067A (en) 1982-10-21 1982-10-21 PLATINUM DIAMINE COMPLEXES, METHOD FOR PREPARING THE SAME, METHOD FOR PREPARING A MEDICINAL PRODUCT USING SUCH PLATINADIAMINE COMPLEX FOR THE TREATMENT OF CANCER, PREVENTLY PREVENTED.

Publications (2)

Publication Number Publication Date
AU2027583A AU2027583A (en) 1984-05-03
AU562964B2 true AU562964B2 (en) 1987-06-25

Family

ID=19840444

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20275/83A Ceased AU562964B2 (en) 1982-10-21 1983-10-18 Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medical composition using a such platinum-diamine complex for the treatment of cancer, as well as the thus shaped composition

Country Status (28)

Country Link
JP (1) JPS5993091A (en)
KR (1) KR910002536B1 (en)
AT (1) AT390610B (en)
AU (1) AU562964B2 (en)
BE (1) BE898058A (en)
CA (1) CA1229618A (en)
CH (1) CH658244A5 (en)
CS (1) CS242888B2 (en)
DD (1) DD217522A5 (en)
DE (1) DE3337333A1 (en)
DK (2) DK483083A (en)
ES (1) ES526670A0 (en)
FI (1) FI76351C (en)
FR (1) FR2534907B1 (en)
GB (1) GB2128615B (en)
GR (1) GR79652B (en)
HU (1) HU188035B (en)
IE (1) IE56124B1 (en)
IT (1) IT1169858B (en)
LU (1) LU85054A1 (en)
NL (1) NL8204067A (en)
NO (1) NO171276C (en)
NZ (1) NZ206018A (en)
PH (1) PH24077A (en)
PT (1) PT77542B (en)
SE (1) SE8305783L (en)
YU (1) YU43554B (en)
ZA (1) ZA837857B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU580072B2 (en) * 1984-06-27 1988-12-22 Johnson Matthey Public Limited Company Platinum co-ordination compounds
AU595827B2 (en) * 1985-08-27 1990-04-12 Nippon Kayaku Kabushiki Kaisha Novel platinum complexes

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
DE3432320A1 (en) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg CIS-PLATINUM COMPLEXES WITH A PENTAERYTHRITE DERIVATIVE AS A LIGAND, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENT CONTAINING THESE COMPOUNDS
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
DE3630497A1 (en) * 1986-09-08 1988-03-10 Behringwerke Ag CIS-PLATINUM COMPLEXES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS
DE3762972D1 (en) * 1986-10-03 1990-07-05 Asta Pharma Ag DIAMINE-PLATIN (II) COMPLEX COMPOUNDS WITH A HYDROXYLATED 2-PHENYL INDOLRING.
JPS63203692A (en) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd Novel platinum complex
AT390065B (en) * 1987-10-08 1990-03-12 Behringwerke Ag cis-Platinum complexes, process for their preparation and pharmaceutical compositions containing these compounds
NL8802150A (en) * 1988-08-31 1990-03-16 Tno PLATINUM (II) DIAMINE COMPLEX, PROCESS FOR PREPARING THIS COMPOUND, PREPARATION WITH ANTI-TUMOR EFFECT, CONTAINING THIS COMPOUND AND FORMED PREPARATIONS WITH ANTI-TUMOR EFFECT.
NL8802149A (en) * 1988-08-31 1990-03-16 Tno PLATINUM (IV) DIAMINE COMPLEX, METHOD FOR PREPARING THIS COMPOUND, PREPARATION WITH ANTI-TUMOR EFFECT, CONTAINING AT LEAST A PLATINUM COMPOUND, AND FORMED PREPARATIONS WITH ANTI-TUMOR EFFECT.
CN102924528B (en) * 2012-10-29 2015-04-15 东南大学 Anti-tumor bivalent platinum complex and preparation method for complex and ligand of complex

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
NL7807334A (en) * 1978-07-06 1980-01-08 Tno PLATINUM DIAMINE COMPLEXES, METHOD FOR PREPARING THE SAME, METHOD FOR PREPARING A MEDICINAL PRODUCT USING SUCH A PLATINUM DIAMOND COMPLEX FOR THE TREATMENT OF CANCER, SO PREVENTLY DRIVED.
NL189358C (en) * 1978-07-06 1993-03-16 Tno PROCESS FOR PREPARING A MEDICINE FOR THE TREATMENT OF CANCER, AND AN PLATINUM-DIAMMINE COMPLEX DERIVED FROM A 1,3-ALKANE DIAMINE.
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes
AU538863B2 (en) * 1980-05-27 1984-08-30 Bristol-Myers Company Platinum complex salts have anti-tumor property

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU580072B2 (en) * 1984-06-27 1988-12-22 Johnson Matthey Public Limited Company Platinum co-ordination compounds
AU595827B2 (en) * 1985-08-27 1990-04-12 Nippon Kayaku Kabushiki Kaisha Novel platinum complexes

Also Published As

Publication number Publication date
CH658244A5 (en) 1986-10-31
NO171276C (en) 1993-02-17
SE8305783L (en) 1984-04-22
DK483083A (en) 1984-04-22
BE898058A (en) 1984-04-24
JPS5993091A (en) 1984-05-29
IT8323359A0 (en) 1983-10-19
DK75592A (en) 1992-06-09
GR79652B (en) 1984-10-31
GB8328084D0 (en) 1983-11-23
LU85054A1 (en) 1984-03-22
ES8406498A1 (en) 1984-07-01
PT77542A (en) 1983-11-01
FI833842A0 (en) 1983-10-20
NO833825L (en) 1984-04-24
HU188035B (en) 1986-03-28
YU210783A (en) 1986-08-31
JPH0244479B2 (en) 1990-10-04
YU43554B (en) 1989-08-31
PT77542B (en) 1986-02-12
ZA837857B (en) 1984-06-27
FI76351B (en) 1988-06-30
CS242888B2 (en) 1986-05-15
CS775283A2 (en) 1985-08-15
CA1229618A (en) 1987-11-24
IE832459L (en) 1984-04-21
FI76351C (en) 1988-10-10
ATA373083A (en) 1989-11-15
FR2534907A1 (en) 1984-04-27
NO171276B (en) 1992-11-09
GB2128615B (en) 1986-07-16
DK483083D0 (en) 1983-10-20
NL8204067A (en) 1984-05-16
SE8305783D0 (en) 1983-10-20
IE56124B1 (en) 1991-04-24
PH24077A (en) 1990-03-05
FI833842L (en) 1984-04-22
FR2534907B1 (en) 1988-08-19
GB2128615A (en) 1984-05-02
DD217522A5 (en) 1985-01-16
AU2027583A (en) 1984-05-03
AT390610B (en) 1990-06-11
DK75592D0 (en) 1992-06-09
IT1169858B (en) 1987-06-03
KR910002536B1 (en) 1991-04-23
KR840006492A (en) 1984-11-30
NZ206018A (en) 1986-02-21
DE3337333A1 (en) 1984-04-26
ES526670A0 (en) 1984-07-01

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