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AU582362B2 - Novel oligosaccharides,their preparation synthesis and their biological applications - Google Patents
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AU582362B2 - Novel oligosaccharides,their preparation synthesis and their biological applications - Google Patents

Novel oligosaccharides,their preparation synthesis and their biological applications

Info

Publication number
AU582362B2
AU582362B2 AU42637/85A AU4263785A AU582362B2 AU 582362 B2 AU582362 B2 AU 582362B2 AU 42637/85 A AU42637/85 A AU 42637/85A AU 4263785 A AU4263785 A AU 4263785A AU 582362 B2 AU582362 B2 AU 582362B2
Authority
AU
Australia
Prior art keywords
biological applications
preparation synthesis
novel oligosaccharides
oligosaccharides
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU42637/85A
Other versions
AU4263785A (en
Inventor
Jean Choay
Jean-Claude Jacquinet
Jean-Claude Lormeau
Maurice Petitou
Pierre Sinay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Choay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choay SA filed Critical Choay SA
Publication of AU4263785A publication Critical patent/AU4263785A/en
Application granted granted Critical
Publication of AU582362B2 publication Critical patent/AU582362B2/en
Assigned to SANOFI-SYNTHELABO reassignment SANOFI-SYNTHELABO Request to Amend Deed and Register Assignors: CHOAY S.A.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The oligosaccharides of the invention contain or consist of a tetrasaccharide chain sequence of formula: <IMAGE> in which R1 denotes an inorganic anion, R2 is identical with R1 or denotes a hydrogen atom, N1 and N2 denote an amine functional group.
AU42637/85A 1984-05-16 1985-05-16 Novel oligosaccharides,their preparation synthesis and their biological applications Expired AU582362B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8407589 1984-05-16
FR8407589A FR2564468B1 (en) 1984-05-16 1984-05-16 NOVEL OLIGOSACCHARIDES, THEIR SYNTHESIS PREPARATION AND THEIR BIOLOGICAL APPLICATIONS

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU10397/83A Addition AU563351C (en) 1982-01-15 1983-01-14 Synthesis of oligosaccharides

Publications (2)

Publication Number Publication Date
AU4263785A AU4263785A (en) 1985-11-21
AU582362B2 true AU582362B2 (en) 1989-03-23

Family

ID=9304040

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42637/85A Expired AU582362B2 (en) 1984-05-16 1985-05-16 Novel oligosaccharides,their preparation synthesis and their biological applications

Country Status (11)

Country Link
EP (1) EP0165134B1 (en)
JP (1) JPH07108911B2 (en)
AT (1) ATE85341T1 (en)
AU (1) AU582362B2 (en)
CA (1) CA1265792A (en)
DE (1) DE3587051T2 (en)
DK (1) DK174284B1 (en)
FR (1) FR2564468B1 (en)
IE (1) IE59101B1 (en)
NZ (1) NZ212094A (en)
ZA (1) ZA853694B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8519416D0 (en) * 1985-08-01 1985-09-04 Unilever Plc Oligosaccharides
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
FR2718849B1 (en) * 1994-04-14 1996-06-14 Pasteur Sanofi Diagnostics Method of immunoassay of antithrombin III activated by a glycosaminoglycan, corresponding monoclonal antibodies and their method of obtaining.
CA2199642C (en) * 1997-03-10 2001-05-08 Roger Cariou Compositions containing an association of aspirin and an anti-xa oligosaccharide and use of an anti-xa oligosaccharide optionally in combination with aspirin
AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
AUPO976897A0 (en) 1997-10-14 1997-11-06 Australian National University, The Use of sulfated oligosaccharides in lowering blood triglyceride levels
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
EP1440077B1 (en) * 2001-09-07 2013-05-01 Alchemia Limited Synthetic heparin pentasaccharides
WO2009155108A1 (en) 2008-05-30 2009-12-23 Momenta Pharmaceuticals, Inc. Saccharide structures and methods of making and using such structures
EP2255817A1 (en) * 2009-05-05 2010-12-01 Sanofi-Aventis Use of an acylated octasaccharide as antithrombotic agent
EP2256137A1 (en) * 2009-05-05 2010-12-01 Sanofi-Aventis Novel sulfated octasaccharide and its use as antithrombotic agent
EP2256139A1 (en) * 2009-05-05 2010-12-01 Sanofi-Aventis Novel sulfated heptasaccharide and its use as antithrombotic agent
EP2256138A1 (en) * 2009-05-05 2010-12-01 Sanofi-Aventis Novel acylated 1,6-anhhydro decasaccharide and its use as antithrombotic agent
EP2256136A1 (en) * 2009-05-05 2010-12-01 Sanofi-Aventis Novel acylated decasaccharides and their use as antithrombotic agents
CN103145774A (en) * 2013-03-21 2013-06-12 苏州鸿洋医药科技有限公司 Anticoagulation pentose and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2613477A (en) * 1976-07-12 1978-12-21 American Cyanamid Co Polygalactosido-sucrose poly (h-)sulfate salts
AU2587184A (en) * 1983-03-23 1984-09-27 Carbohydrates International A.B. Compound and composition for therapy or diaenosis
AU563351B2 (en) * 1982-01-15 1987-07-09 Glaxo Group Limited Synthesis of oligosaccharides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
CA1171375A (en) * 1980-09-15 1984-07-24 Ulf P.F. Lindahl Oligosaccharides having selective anticoagulation activity
FR2519987A1 (en) * 1982-01-15 1983-07-22 Choay Sa Uronic acid derivs. - useful as glycoside intermediates or hapten(s)

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2613477A (en) * 1976-07-12 1978-12-21 American Cyanamid Co Polygalactosido-sucrose poly (h-)sulfate salts
AU563351B2 (en) * 1982-01-15 1987-07-09 Glaxo Group Limited Synthesis of oligosaccharides
AU2587184A (en) * 1983-03-23 1984-09-27 Carbohydrates International A.B. Compound and composition for therapy or diaenosis

Also Published As

Publication number Publication date
EP0165134A2 (en) 1985-12-18
JPH07108911B2 (en) 1995-11-22
DE3587051D1 (en) 1993-03-18
JPS60260590A (en) 1985-12-23
DE3587051T2 (en) 1993-08-19
FR2564468B1 (en) 1994-12-23
FR2564468A2 (en) 1985-11-22
DK215985D0 (en) 1985-05-15
ZA853694B (en) 1986-01-29
AU4263785A (en) 1985-11-21
NZ212094A (en) 1988-11-29
DK174284B1 (en) 2002-11-11
DK215985A (en) 1985-11-17
IE851214L (en) 1985-11-16
IE59101B1 (en) 1994-01-12
EP0165134A3 (en) 1988-02-24
CA1265792A (en) 1990-02-13
ATE85341T1 (en) 1993-02-15
EP0165134B1 (en) 1993-02-03

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Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: SANOFI-SYNTHELABO

Free format text: FORMER NAME WAS: CHOAY S.A.