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AU609433B2 - Enzymatic dishwashing composition - Google Patents
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AU609433B2 - Enzymatic dishwashing composition - Google Patents

Enzymatic dishwashing composition Download PDF

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Publication number
AU609433B2
AU609433B2 AU82225/87A AU8222587A AU609433B2 AU 609433 B2 AU609433 B2 AU 609433B2 AU 82225/87 A AU82225/87 A AU 82225/87A AU 8222587 A AU8222587 A AU 8222587A AU 609433 B2 AU609433 B2 AU 609433B2
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AU
Australia
Prior art keywords
lipase
pseudomonas
lipases
composition
proteases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU82225/87A
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AU8222587A (en
Inventor
Willem Robert Van Dijk
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Unilever PLC
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Unilever PLC
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Filing date
Publication date
Application filed by Unilever PLC filed Critical Unilever PLC
Publication of AU8222587A publication Critical patent/AU8222587A/en
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Publication of AU609433B2 publication Critical patent/AU609433B2/en
Anticipated expiration legal-status Critical
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Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627Preparations containing enzymes, e.g. protease or amylase containing lipase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)

Description

1 111 1 .4111~
AUSTRALIA
PATENTS ACT 1952 Form COMPLETE SPECIFICATION
(ORIGINAL)
FOR OFFICE USE 609433 Short Title: Int. Cl: Application Number: Lodged: t Complete Specification-Lodged: Accepted: Lapsed: SPublished: S Priority: Related Art: t C TO BE COMPLETED BY APPLICANT Name of Applicant: Address of Applicant: UNILEVER PLC UNILEVER HOUSE
BLACKFRIARS
LONDON EC4
ENGLAND
C C
'C
Actual Inventor: Address for Service: CLEMENT HACK CO., 601 St. Kilda Road, Melbourne, Victoria 3004, Australia.
Complete Specification for the invention entitled: ENZYMATIC DISHWASHING COMPOSITION The following statement is a full description of this invention including the best method of performing it known to me:- MAIL OFFICE ONEff HUNDRED DOLLARS TWENTY DOLLARS TEN DOLLARS c 7096(R) 1A ENZYMATIC DISHWASHING COMPOSITION The present invention relates to an enzymatic dishwashing composition comprising proteases and a special class of lipases.
The use of enzymes in dishwashing compositio s, both for manual as well as mechanical dishwashing is generally well-known in the art. For that purpose, in particular amylases and/or proteases have been proposed.
Sc Although lipases as a general class of enzymes have also been suggested, no specific proposals relating to the use of specific lipases in dishwashing compositions Sc have been made as far as we know.
v In dishwashing, the removal of egg-yolk, particularly dried-up or baked-on egg-yolk from the surface of the S" dishware is often a problem, and the satisfactory removal of this type of soil often requires special measures -or special dishwashing compositions.
We have now surprisingly found that the inclusion of proteases and a special class of lipases in dishwashing compositions provide for a satisfactory removal of eggyolk from the dishware. This removal is significantly superior to the removal, obtained with either the proteases or the lipases, and the combination of these two types of enzymes in fact produces a synergistic cleaning effect in this respect.
The proteases which can be used in the present inventioni can be any type of protease known for inclusion in detergent compositions. Most commercially available proteases are of the subtilisin type, and suitable examples of such proteases are Alcalase, .r
L
SC 7096(R) 2 Esperase and Savinase, sold by NOVO Industri; Maxatase and Maxacal, sold by Gist Brocades; Optimase sold by Kali Chemie; Kazusase, sold by Showa Denka. Preferred are the so-called high alkaline proteases such as Savinase. Mixtures of various proteases can also be used. In general, the dishwashing compositions of the invention contain the proteases in such an amount, that the final composition has a proteolytic activity of 0.1 50, usually 1 40 and preferably 5 -30 GU/mg. A GU is a glycin unit, which is the amount of enzyme cc which under standard incubation conditions produces an cc amount of terminal NH 2 -groups equivalent to 1 m' icrogramme/ml glycin.
The class of lipases to be used according to the c present invention embraces those lipases which show a positive immunological cross-reaction with the antibody of the lipase, produced by the microorganism Scc* Chromobacter viscosum var. lipolyticum NRRL-B 3673.
20 This lipase has been described in Dutch Patent Specification 154,269 of Toyo Jozo KK, and the 2 5 microorganism is available to the public at the United States Department of Agriculture, Agricultural Research Service, Northern Utilization and Development Division c 25 at Peoria, Illinois, under the number NRRL-B 3673. This lipase will hereinafter be referred to as "Toyo Jozo" lipase. Th- lipases of the present invention should show a positive immunological cross reaction with the Toyo Jozo lipase antibody, using the standard and well- 30 known immunodiffusion procedure according to Ouchterlony (Acta. Med. Scan., 133, pages 76-79 (1950)).
The preparation of the antiserum is carried out as follows: Equal volume of 0.1 mg/ml antigen and of Freund's adjuvant (complete or incomplete) are mixed until an i C 7096(R) 3 emulsion is obtained. Two female rabbits are injected with 2 ml samples of the emulsion according to the following scheme: day 0 antigen in complete Freund's adjuvant day 4 antigen in complete Freund's adjuvant day 32 antigen in incomplete Freund's adjuvant day 60 booster of antigen in incomplete Freund's adjuvant r t The serum containing the required antibody is prepared by centrifugation of clotted blood, taken on day 67.
a 1t C The titre of the anti-Toyo Jozo-lipase antiserum is Cr 15 determined by the inspection of precipitation of serial cc dilutions of antigen and antiserum according to the Ouchterlony procedure. A 25 dilution of antiserum was the dilution that still gave a visible precipitation S0oo with an antigen concentration of 0.1 mg/ml.
0I o 0 All lipases showing a positive immunological cross reaction with Toyo Jozo lipase antibody as hereabove described are lipases according to the present invention. Typical examples thereof are the lipase ex o 25 Pseudomonas fluorescens IAM 1057 (available under the trade name Amano-P), the lipase ex Pseudomonas fragi FERM P 1339 (available under the trade name Amano-B), lipase ex Pseudomonas nitroreducens v r. lipolyticum i FERM P 1338, the lipase ex Pseudomonas sp., available under the trade name Amano-CES, the lipase ex Pseudomonas cepacia, lipases ex Chromobacter viscosum, e.g. Chromobacter viscosum var. lipolyticum NRRL B- 3673, commercially available from Toyo Jozo Co., Tagata, Japan; and further Chromobacter viscosum lipases from US Biochemical Corp., U.S.A. and Diosynth Co., The Netherlands, and lipases ex Pseudomonas gladioli.
C 7096(R) 4 The lipases of the present invention are included in the dishwashing composition in such an amount that the final dishwashing composition has a lipolytic enzyme activity of from 100 to 0.005 LU/mg preferably 25 to 0.05 LU/mg of the composition.
A Lipase Unit (LU) is that amount of lipase which produces 1umol of titratable fatty acid per minute in a pH stat. under the following conditions: temperature 30OC; pH 9.0; substrate is an emulsion of e, 3.3 wt of olive oil and 3.3 gum arabic, in the ,C presence of 13 mmol/l Ca 2 and 20 mmol/l NaCl in mmol/l Tris-buffer.
Naturally, mixtures of the above lipases can be used.
The lipases can be used in their non-purified form, or in a purified form, e.g. purified with the aid of wellknown adsorption methods, such as phenylsepharose as adsorption techniques.
4 The dishwashing compositions of the present invention may furthermore comprise the usual ingredients of CC0 dishwashing compositions. Thus, they may comprise a small amount, in the order of 0.5 5 by weight of a detergent surfactant, e.g. anionic or nonionic surfactants, such as a low or non-foaming nonionic surfactant. Such low or non--foaming nonionic surfactants are well-known in the art, and suitable examples can be found in M. Schick "Nonionic Surfactants" Vol. 1, (1967).
Furthermore, they may comprise organic and/or inorganic builder materials, usually in amounts of from 10 80 for most practical purposes from 20 60 by weight.
Such builder materials include alkali metal polyphosphates, -pyrophosphates, -hexametaphosphates, -orthophosphates, -carbonates, -bicarbonates, -borates, -i I i i 1 i C 7096(R) -silicates; furthermore, alkali metal polycarboxylates and -polyhydroxysulphonates. Additional examples include alkali metal citrates, -nitrilotriacetates, -carboxymethyloxysuccinates, zeolites etc.
Polyelectrolytes such as polymaleates and polyacrylates are also suitable examples.
Furthermore, peroxy-type bleaching agents may be included such as alkalimetal perborates, -percarbonates, -persulphates as well as organic Srperacids and salts thereof. Bleach precursors such as c tetraacetylethylenediamine may also be included e c t c c together with a peroxy type bleaching agents such as sodium perborate.
Sc Buffers, perfumes, dyes, germicides, solvents, foam Cc depressors, clays such as hectorites, corrosion inhibitors anti-tarnishing agents etc. may also be r included if required.
Other enzymes such as amylases, cellulases, pectinases, pectin-esterases or oxidases may also be included. The compositions may be formulated in any desired form, such as powders, bars, cakes, blocks, pastes and cc 25 liquids. The invention will further be illustrated by way of Example.
Example 1 Tests were carried out with an aqueous solution containing the following base formulation: 9/1 pentasodium triphosphate 1.16 sodium carbonate 0 aq. 0.27 sodium disilicate 0.33 sodium sulphate 0 aq. 0.561 C 7096(R) 6 Comparisons were carried out with this formulation without enzymes, with Toyo Jozo lipase (0.25 with Savinase 6.0 CM (0.023 g/l) or with a mixture of these enzymes.
A set of 8 glass plates (4 x 4 cm) were soiled with 51.5 1.8 mg baked-on egg yolk per glass plate. These were soaked in 1 liter water of 27 0 GH containing the above amounts of the dishwashing composition for a period of one hour at pH 10.0. After soaking the residual egg-yolk present on the plates was determined ti by weighing and measuring the weight difference of the soiled plates before and after soaking.
The difference (DW) is expressed as a percentage of the C4e original amount of soil. The tests were repeated three times independently. The following results were obtained: a DW (in 20 no enzymes 96.4 95.5 95.2 c 0 only lipase 97.1 96.0 I 95.3 only Savinase 56.7 47.2 I 51.7 lipase Savinase: 22.3 20.5 I 22.9 At 35 and 45°C similar results were obtained. Replacing Savinase by Alcalase also produced similar results.
Example 2 Repeating Example 1, but using the Amano-P lipase, gave the following results: DW (in no enzymes 97 only lipase only Savinase 52 lipase Savinase: a.~P -I C 7096(R) Example 3 Glasses were cleaned in a Kenmore Sears dishwashing machine, using the normal wash programme at followed by a hot dry. The water hardness was 14.4 0
FH.
The dishwashing composition was dosed in an amount of g, and had the following formulation: by weight 24 sodium tripolyphosphate soda ash sodium disilicate *4 4 4~ Cs S I L Or.
4 54, *c 4 .5 45 C C' linear C 10 alcohol, condensed with 6 moles of ethylene oxide and 24 moles of propylene oxide sodium sulphate 27.8 Amylase (4.8 MU/mg) protease (SavinaseG) (1544 GU/mg) Toyo Jozo lipase 15 LU/ml.
20 The soiling was 6 g egg-yolk.
The glasses were washed consecutively several times, and the film formation was thereafter assessed using a scale of 0 5, 0 being no film at all and 5 being very severe film formation. These experiments were also carried out with the same formulation, but without lipase or without Savinase or without lipase and Savinase.
The following results were obtained: Number of Film consecutive washes score Base powder 3 0.5 Base powder lipase 15 1.7 Base powder Savinase 15 2.3 Base powder lipase Savinase 15 0.3 severe spot formation occurred.

Claims (2)

1. An enzymatic dishwashing composition comprising from 0.5-5% by weight of a detergent surfactant, from 10-80% by weight of a builder, and proteases in an amount such that the composition has a prcteolytic activity of 0.1-50 Glycine Units per milligram, characterised in that it further comprises from 0.005-100 LU/mg of a bacterial lipase which shows a positive immunological cross-reaction with the antibody of the lipase, produced by Chromobacter S' 10 viscosum var. lipolyticum NRRL B 3673.
2. A composition according to claim 1, characterised in that the lipase is producible by Pseudomonas fluorescens, Pseudomonas fragi, Pseudomonas nitroreducens var. lipolyticum, Pseudomonas cepacia, Pseudomonas gladioli and Chromobacter viscosum. tt t DATED THIS 8TH DAY OF DECEMBER 1987 SUNILEVER PLC By its Patent Attorneys: CLEMENT HACK CO. Fellows Institute of Patent Attorneys of Australia. i
AU82225/87A 1986-12-10 1987-12-08 Enzymatic dishwashing composition Ceased AU609433B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868629537A GB8629537D0 (en) 1986-12-10 1986-12-10 Enzymatic dishwashing composition
GB8629537 1986-12-10

Publications (2)

Publication Number Publication Date
AU8222587A AU8222587A (en) 1988-06-16
AU609433B2 true AU609433B2 (en) 1991-05-02

Family

ID=10608787

Family Applications (1)

Application Number Title Priority Date Filing Date
AU82225/87A Ceased AU609433B2 (en) 1986-12-10 1987-12-08 Enzymatic dishwashing composition

Country Status (9)

Country Link
EP (1) EP0271156B1 (en)
JP (1) JPH0647679B2 (en)
AU (1) AU609433B2 (en)
BR (1) BR8706684A (en)
CA (1) CA1288369C (en)
DE (1) DE3763814D1 (en)
ES (1) ES2017711B3 (en)
GB (1) GB8629537D0 (en)
ZA (1) ZA879299B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0697997B2 (en) * 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ New enzymatic detergent additive
BE1001436A3 (en) * 1988-02-22 1989-10-31 Synfina Sa New lipase and detergent compositions containing.
GB8813687D0 (en) * 1988-06-09 1988-07-13 Unilever Plc Enzymatic dishwashing & rinsing composition
JPH0277499A (en) * 1988-09-14 1990-03-16 Lion Corp Cleaning composition for automatic dishwashers
US4959179A (en) * 1989-01-30 1990-09-25 Lever Brothers Company Stabilized enzymes liquid detergent composition containing lipase and protease
US5089163A (en) * 1989-01-30 1992-02-18 Lever Brothers Company, Division Of Conopco, Inc. Enzymatic liquid detergent composition
JPH0699714B2 (en) * 1990-07-11 1994-12-07 花王株式会社 Detergent composition for automatic dishwasher
JP2986595B2 (en) * 1991-11-08 1999-12-06 ダイセル化学工業株式会社 New lipase
CA2088230A1 (en) * 1992-02-03 1993-08-04 James Gordon Detergent composition
AU694268B2 (en) * 1994-09-06 1998-07-16 S.C. Johnson & Son, Inc. A cleaning composition comprising lipase and amylase enzymes
BRPI0808513A2 (en) 2007-03-09 2014-08-19 Danisco Us Inc Genencor Div ALPHA-AMILASE VARIANTS OF ALKALIFYL BACILLUS SPECIES, COMPOSITIONS UNDERSTANDING ALPHA-AMYLASE VARIANTS AND METHODS OF USE
BRPI0913378A2 (en) 2008-06-06 2015-09-01 Danisco Us Inc Glucose production from starch using bacillus subtilis alpha-amylase
MX364987B (en) 2008-06-06 2019-05-17 Danisco Us Inc Variant alpha-amylases from bacillus subtilis and methods of use, thereof.
CA2726631A1 (en) 2008-06-06 2009-12-10 Danisco Us Inc. Saccharification enzyme composition and method of saccharification thereof
WO2010036515A1 (en) 2008-09-25 2010-04-01 Danisco Us Inc. Alpha-amylase blends and methods for using said blends
CA2778471A1 (en) 2009-10-23 2011-04-28 Danisco Us Inc. Methods for reducing blue saccharide

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0205208A2 (en) * 1985-06-11 1986-12-17 Unilever N.V. Enzymatic detergent composition
US4707291A (en) * 1985-06-11 1987-11-17 Lever Brothers Company Enzymatic detergent composition

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
DE1619087A1 (en) * 1967-08-14 1969-10-02 Henkel & Cie Gmbh Surfactant combinations which can be used as laundry detergents and detergents or auxiliary washing agents containing them
GB1273545A (en) * 1968-06-24 1972-05-10 Albright & Wilson Multi-enzyme cleaning compositions
DK289083A (en) * 1983-06-23 1984-12-24 Novo Industri As LIPASE, PROCEDURE FOR PREPARING THEREOF AND ITS APPLICATION
DK154572C (en) * 1985-08-07 1989-04-24 Novo Industri As ENZYMATIC DETERGENT ADDITIVE, DETERGENT AND METHOD FOR WASHING TEXTILES
JPS6434560A (en) * 1987-07-30 1989-02-06 Seiko Epson Corp Die structure
JPS6434559A (en) * 1987-07-30 1989-02-06 Seiko Epson Corp Structure for taking out cavity

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0205208A2 (en) * 1985-06-11 1986-12-17 Unilever N.V. Enzymatic detergent composition
US4707291A (en) * 1985-06-11 1987-11-17 Lever Brothers Company Enzymatic detergent composition

Also Published As

Publication number Publication date
DE3763814D1 (en) 1990-08-23
EP0271156A2 (en) 1988-06-15
GB8629537D0 (en) 1987-01-21
AU8222587A (en) 1988-06-16
ES2017711B3 (en) 1991-03-01
JPH0647679B2 (en) 1994-06-22
JPS63159498A (en) 1988-07-02
BR8706684A (en) 1988-07-19
EP0271156B1 (en) 1990-07-18
ZA879299B (en) 1989-08-30
EP0271156A3 (en) 1988-08-03
CA1288369C (en) 1991-09-03

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