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AU630516B2 - Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells - Google Patents
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AU630516B2 - Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells - Google Patents

Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells

Info

Publication number
AU630516B2
AU630516B2 AU65781/90A AU6578190A AU630516B2 AU 630516 B2 AU630516 B2 AU 630516B2 AU 65781/90 A AU65781/90 A AU 65781/90A AU 6578190 A AU6578190 A AU 6578190A AU 630516 B2 AU630516 B2 AU 630516B2
Authority
AU
Australia
Prior art keywords
polypeptides
processes
producing
stimulating factor
colony stimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU65781/90A
Other versions
AU6578190A (en
Inventor
John F. DeLamarter
Johachim F. Ernst
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of AU6578190A publication Critical patent/AU6578190A/en
Application granted granted Critical
Publication of AU630516B2 publication Critical patent/AU630516B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU65781/90A 1985-10-03 1990-11-05 Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells Expired - Fee Related AU630516B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78341485A 1985-10-03 1985-10-03
US783414 1985-10-03

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU65493/86A Division AU606585B2 (en) 1985-10-03 1986-10-03 Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells

Publications (2)

Publication Number Publication Date
AU6578190A AU6578190A (en) 1991-01-10
AU630516B2 true AU630516B2 (en) 1992-10-29

Family

ID=25129176

Family Applications (2)

Application Number Title Priority Date Filing Date
AU65493/86A Ceased AU606585B2 (en) 1985-10-03 1986-10-03 Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells
AU65781/90A Expired - Fee Related AU630516B2 (en) 1985-10-03 1990-11-05 Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU65493/86A Ceased AU606585B2 (en) 1985-10-03 1986-10-03 Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells

Country Status (5)

Country Link
EP (1) EP0238655A4 (en)
JP (1) JPS63502795A (en)
AU (2) AU606585B2 (en)
DK (1) DK282887A (en)
WO (1) WO1987002060A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US5242811A (en) * 1985-03-26 1993-09-07 Biogen, Inc. Production of human somatomedin C
DE3712985A1 (en) * 1987-04-16 1988-11-03 Hoechst Ag BIFUNCTIONAL PROTEINS
DE3545568A1 (en) * 1985-12-21 1987-07-16 Hoechst Ag GM-CSF-PROTEIN, ITS DERIVATIVES, PRODUCTION OF SUCH PROTEINS AND THEIR USE
EP0276846A3 (en) * 1987-01-29 1989-07-26 Zymogenetics, Inc. Colony-stimulating factor derivatives
JPS6420097A (en) * 1987-03-02 1989-01-24 Sumitomo Chemical Co Human granulocyte-macrophage colony stimulating factor
DE3853590T2 (en) * 1987-06-25 1996-01-04 Immunex Corp CATTLE GRANULOCYT MACROPHAGE COLONY STIMULATING FACTOR.
ZA885101B (en) * 1987-07-17 1989-03-29 Schering Biotech Corp Human granulocyte macrophage colony stimulating factor and muteins thereof
JPH03502322A (en) * 1987-10-30 1991-05-30 イミュネックス・コーポレーション Non-glycosylated analogs of human colony-stimulating factor
GB2212159B (en) * 1987-11-13 1992-01-22 British Bio Technology Synthetic gene for human granulocyte/macrophage colony stimulating factor.
EP0413721A4 (en) * 1988-04-21 1991-11-13 Medvet Science Pty. Ltd. Human gm-csf variants
WO1989010158A1 (en) * 1988-04-27 1989-11-02 Immunomedics, Inc. Improved radiotherapy
DE69001686T2 (en) * 1989-01-30 1993-09-02 Schering Corp TREATING LEUCOCYTIC DISORDERS WITH GM-CSF.
EP0791061A4 (en) * 1994-03-04 1998-07-15 Ludwig Inst Cancer Res ANIMALS WITH TARGETED INTERRUPTION
RU2144083C1 (en) * 1998-03-13 2000-01-10 Государственный научный центр вирусологии и биотехнологии "Вектор" Method of industrial producing human recombinant granulocyte-macrophage colony-stimulating factor
US6979442B1 (en) 1998-08-17 2005-12-27 Pfizer Inc. Stabilized protein compositions
ES2411007T3 (en) 2001-10-10 2013-07-04 Novo Nordisk A/S Remodeling and glycoconjugation of peptides
CN102159230A (en) 2008-07-23 2011-08-17 Ambrx公司 Modified bovine G-CSF polypeptides and uses thereof
TWI480288B (en) 2010-09-23 2015-04-11 Lilly Co Eli Formulations for bovine granulocyte colony stimulating factor and variants thereof
JP6698854B2 (en) * 2016-09-16 2020-05-27 キッセイ薬品工業株式会社 Genetically modified cell and method for producing the same
CN119842769A (en) * 2025-01-21 2025-04-18 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) Prokaryotic expression plasmid of recombinant feline macrophage colony stimulating factor and construction method and application thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030654B2 (en) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 Method for producing human colony stimulating factor
UA39161C2 (en) * 1984-07-06 2001-06-15 Новартіс Аг Recombinant protein of GM-CSF for increase in productION of granylocytes and macrophages by patients, vector and cdna coding it
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene
JP3038348B2 (en) * 1984-11-20 2000-05-08 シェーリング コーポレイション CDNA clones encoding polypeptides exhibiting cell growth factor activity of human granular, macrophages and eosinophils
US5391485A (en) * 1985-08-06 1995-02-21 Immunex Corporation DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues
DE3545568A1 (en) * 1985-12-21 1987-07-16 Hoechst Ag GM-CSF-PROTEIN, ITS DERIVATIVES, PRODUCTION OF SUCH PROTEINS AND THEIR USE

Also Published As

Publication number Publication date
WO1987002060A1 (en) 1987-04-09
AU6578190A (en) 1991-01-10
EP0238655A4 (en) 1989-09-11
DK282887A (en) 1987-07-30
AU6549386A (en) 1987-04-24
EP0238655A1 (en) 1987-09-30
DK282887D0 (en) 1987-06-02
AU606585B2 (en) 1991-02-14
JPS63502795A (en) 1988-10-20

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