AU633041B2 - Method for the determination of immunologically detectable substances - Google Patents
Method for the determination of immunologically detectable substancesInfo
- Publication number
- AU633041B2 AU633041B2 AU48582/90A AU4858290A AU633041B2 AU 633041 B2 AU633041 B2 AU 633041B2 AU 48582/90 A AU48582/90 A AU 48582/90A AU 4858290 A AU4858290 A AU 4858290A AU 633041 B2 AU633041 B2 AU 633041B2
- Authority
- AU
- Australia
- Prior art keywords
- determination
- solid phase
- bound
- binding
- specific binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
For the determination of immunologically detectable substances by the principle of the heterogeneous immunoassay by incubation with at least two receptors R1 and R2, of which R1 mediates the binding to the solid phase and R2 is a conjugate of a ligand which is able to bind to a substance to be determined and of a label, using a solid phase to which a reaction component capable of specific binding is bound, separation of the solids from the liquid phase and determination of the label in one of the two phases, the solid phase is a material to whose surface are bound partners capable of specific binding, and the sample solution is incubated with a plurality of different receptors R1, where each receptor R1 has both binding sites for the partner which is capable of specific binding and is bound to the solid phase and binding sites for one of the substances to be determined. <IMAGE>
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3901638A DE3901638C2 (en) | 1988-05-25 | 1989-01-20 | Method for determining an immunologically detectable substance and suitable reaction vessel |
| DE3901638 | 1989-01-20 | ||
| DE19893924239 DE3924239A1 (en) | 1989-07-21 | 1989-07-21 | METHOD FOR DETERMINING IMMUNOLOGICALLY DETECTABLE SUBSTANCES |
| DE3924239 | 1989-07-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4858290A AU4858290A (en) | 1990-07-26 |
| AU633041B2 true AU633041B2 (en) | 1993-01-21 |
Family
ID=25876968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU48582/90A Ceased AU633041B2 (en) | 1989-01-20 | 1990-01-19 | Method for the determination of immunologically detectable substances |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0379216B1 (en) |
| JP (1) | JPH0827284B2 (en) |
| AT (1) | ATE107030T1 (en) |
| AU (1) | AU633041B2 (en) |
| CA (1) | CA2008100A1 (en) |
| DE (1) | DE59005973D1 (en) |
| DK (1) | DK0379216T3 (en) |
| ES (1) | ES2055172T3 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7410802B2 (en) | 1999-07-30 | 2008-08-12 | Bioe, Inc. | Methods for simultaneously detecting both members of a binding pair |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4211108A1 (en) * | 1992-04-03 | 1993-10-07 | Boehringer Mannheim Gmbh | Virus solution for use in immunoassays |
| DE4218257A1 (en) * | 1992-06-03 | 1993-12-09 | Behringwerke Ag | Method for immunochemical determination of an analyte |
| WO1994003807A1 (en) * | 1992-08-03 | 1994-02-17 | Gec-Marconi Limited | Separation method |
| GB2271634B (en) * | 1992-09-18 | 1997-04-09 | Marconi Gec Ltd | Separation method |
| DE4236189A1 (en) * | 1992-10-27 | 1994-04-28 | Boehringer Mannheim Gmbh | Method for the simultaneous determination of antigens and antibodies |
| GB2273157A (en) * | 1992-11-27 | 1994-06-08 | Marconi Gec Ltd | Immunological detection/separation using a plurality of immobilised binding agents |
| GB2282884A (en) * | 1993-04-14 | 1995-04-19 | Int Murex Tech Corp | Immunoassay |
| AU6508694A (en) * | 1993-04-14 | 1994-11-08 | International Murex Technologies Corporation | Immunoassay |
| JP5500423B2 (en) * | 2009-12-24 | 2014-05-21 | 東洋紡株式会社 | Allergy test method |
| CN116879550A (en) * | 2019-12-31 | 2023-10-13 | 科美博阳诊断技术(上海)有限公司 | Human immunodeficiency virus antibody detection kit and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2181840A (en) * | 1985-10-16 | 1987-04-29 | Farmos Group Ltd | Method for the immunoassay of a macromolecular analyte |
| FR2601455A1 (en) * | 1986-07-11 | 1988-01-15 | Stallergenes Lab | New biological reactants in solid phase and process for obtaining them |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5510590A (en) * | 1978-05-04 | 1980-01-25 | Wellcome Found | Enzyme immunity quantity analysis |
| IL55816A (en) * | 1978-10-30 | 1982-04-30 | Ames Yissum Ltd | Method for simultaneous immunoassay of several different antibodies and a kit therefor |
| US4378344A (en) * | 1979-09-28 | 1983-03-29 | Ventrex Laboratories, Inc. | Method and apparatus for performing multiple, simultaneous in vitro diagnostic tests using a solid phase system |
| ZA855031B (en) * | 1984-08-31 | 1986-02-26 | New York Blood Center Inc | Assay for simultaneous detection of antigen and antibody in given serum |
| US4772550A (en) * | 1986-02-10 | 1988-09-20 | Miles Inc. | Heterogeneous specific binding assay employing an aggregatable binding reagent |
| US4778751A (en) * | 1986-05-12 | 1988-10-18 | Diagnostic Products Corporation | Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies |
| DE3705686C2 (en) * | 1987-02-23 | 1995-11-30 | Boehringer Mannheim Gmbh | Methods for the determination of antibodies |
-
1990
- 1990-01-18 CA CA002008100A patent/CA2008100A1/en not_active Abandoned
- 1990-01-19 EP EP90101095A patent/EP0379216B1/en not_active Expired - Lifetime
- 1990-01-19 AU AU48582/90A patent/AU633041B2/en not_active Ceased
- 1990-01-19 DK DK90101095.9T patent/DK0379216T3/en active
- 1990-01-19 ES ES90101095T patent/ES2055172T3/en not_active Expired - Lifetime
- 1990-01-19 JP JP2008556A patent/JPH0827284B2/en not_active Expired - Lifetime
- 1990-01-19 AT AT90101095T patent/ATE107030T1/en not_active IP Right Cessation
- 1990-01-19 DE DE59005973T patent/DE59005973D1/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2181840A (en) * | 1985-10-16 | 1987-04-29 | Farmos Group Ltd | Method for the immunoassay of a macromolecular analyte |
| FR2601455A1 (en) * | 1986-07-11 | 1988-01-15 | Stallergenes Lab | New biological reactants in solid phase and process for obtaining them |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7410802B2 (en) | 1999-07-30 | 2008-08-12 | Bioe, Inc. | Methods for simultaneously detecting both members of a binding pair |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2055172T3 (en) | 1994-08-16 |
| ATE107030T1 (en) | 1994-06-15 |
| DK0379216T3 (en) | 1994-10-31 |
| JPH02228561A (en) | 1990-09-11 |
| EP0379216B1 (en) | 1994-06-08 |
| JPH0827284B2 (en) | 1996-03-21 |
| DE59005973D1 (en) | 1994-07-14 |
| EP0379216A1 (en) | 1990-07-25 |
| CA2008100A1 (en) | 1990-07-20 |
| AU4858290A (en) | 1990-07-26 |
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