AU646596B2 - Substituted imidazolyl-propenoic acid derivatives - Google Patents

Substituted imidazolyl-propenoic acid derivatives

Info

Publication number: AU646596B2
Authority: AU; Australia
Prior art keywords: acid derivatives; propenoic acid; substituted imidazolyl; imidazolyl; substituted
Prior art date: 1991-10-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

AU26024/92A

Other versions

AU2602492A (en

Inventor

Martin Dr. Beuck

Jurgen Dressel

Rudolf Dr. Hanko

Walter Dr. Hubsch

Stanislav Prof. Dr. Kazda

Andreas Dr. Knorr

Thomas Dr. Kramer

Ulrich Dr. Muller

Matthias dr. Muller-Gliemann

Johannes-Peter Dr. Stasch

Stefan Dr. Wohlfeil

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer AG

Original Assignee

Bayer AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-01

Filing date

1992-09-29

Publication date

1994-02-24

1992-09-29 Application filed by Bayer AG filed Critical Bayer AG

1993-04-08 Publication of AU2602492A publication Critical patent/AU2602492A/en

1994-02-24 Application granted granted Critical

1994-02-24 Publication of AU646596B2 publication Critical patent/AU646596B2/en

2012-09-29 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

ZLSNPZVGNMESDB-UHFFFAOYSA-N 2-(1h-imidazol-2-yl)prop-2-enoic acid Chemical class OC(=O)C(=C)C1=NC=CN1 ZLSNPZVGNMESDB-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AU26024/92A 1991-10-01 1992-09-29 Substituted imidazolyl-propenoic acid derivatives Expired - Fee Related AU646596B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4132632		1991-10-01
DE4132632A DE4132632A1 (en)	1991-10-01	1991-10-01	SUBSTITUTED IMIDAZOLYL-PROPENSAEUREDERIVATE

Publications (2)

Publication Number	Publication Date
AU2602492A AU2602492A (en)	1993-04-08
AU646596B2 true AU646596B2 (en)	1994-02-24

Family

ID=6441874

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU26024/92A Expired - Fee Related AU646596B2 (en)	1991-10-01	1992-09-29	Substituted imidazolyl-propenoic acid derivatives

Country Status (15)

Country	Link
EP (1)	EP0539713A1 (en)
JP (1)	JPH05213939A (en)
KR (1)	KR930007937A (en)
AU (1)	AU646596B2 (en)
CA (1)	CA2079268A1 (en)
CZ (1)	CZ297692A3 (en)
DE (1)	DE4132632A1 (en)
FI (1)	FI924355A7 (en)
HU (1)	HUT62576A (en)
IL (1)	IL103293A0 (en)
MX (1)	MX9205435A (en)
NO (1)	NO923580L (en)
SK (1)	SK297692A3 (en)
TW (1)	TW206223B (en)
ZA (1)	ZA927500B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4132633A1 (en) *	1991-10-01	1993-04-08	Bayer Ag	CYCLICALLY SUBSTITUTED IMIDAZOLYL-PROPENEASE DERIVATIVES
DE4132631A1 (en) *	1991-10-01	1993-04-08	Bayer Ag	IMIDAZOLYL-propenoic acid derivatives
AT398202B (en) *	1991-10-04	1994-10-25	Chem Pharm Forsch Gmbh	NEW IMIDAZOLE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
GB9218449D0 (en)	1992-08-29	1992-10-14	Boots Co Plc	Therapeutic agents
EP0668272B1 (en) *	1994-01-28	2000-07-12	Takeda Chemical Industries, Ltd.	A process for the production of tetrazolyl compounds
CA2186606A1 (en) *	1994-03-29	1995-10-05	Edward B. Nelson	Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles
US6465502B1 (en) *	1998-12-23	2002-10-15	Novartis Ag	Additional therapeutic use
CN1304000C (en) *	1998-12-23	2007-03-14	诺瓦提斯公司	Use of valsartan in the preparation of medicines for the treatment of lung cancer
EP1013273A1 (en) *	1998-12-23	2000-06-28	Novartis AG	Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX354786B (en)	2007-06-04	2018-03-21	Synergy Pharmaceuticals Inc	AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER and OTHER DISORDERS.
ES2522968T3 (en)	2008-06-04	2014-11-19	Synergy Pharmaceuticals Inc.	Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AU2009270833B2 (en)	2008-07-16	2015-02-19	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
AU2014235215A1 (en)	2013-03-15	2015-10-01	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
AU2014235209B2 (en)	2013-03-15	2018-06-14	Bausch Health Ireland Limited	Guanylate cyclase receptor agonists combined with other drugs
BR112015030326A2 (en)	2013-06-05	2017-08-29	Synergy Pharmaceuticals Inc	ULTRAPURE GUANYLATE CYCLASE C AGONISTS, METHOD OF MANUFACTURING AND USING THEM

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8043691A (en) *	1990-08-09	1992-02-13	Zeneca Limited	Process for the manufacture of biphenylcarbonitriles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0403159T3 (en) *	1989-06-14	2000-08-14	Smithkline Beecham Corp	imidazolyl
EP0403158A3 (en) *	1989-06-14	1991-12-18	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids

1991
- 1991-10-01 DE DE4132632A patent/DE4132632A1/en not_active Withdrawn
1992
- 1992-09-14 TW TW081107194A patent/TW206223B/zh active
- 1992-09-15 NO NO92923580A patent/NO923580L/en unknown
- 1992-09-18 EP EP92115969A patent/EP0539713A1/en not_active Withdrawn
- 1992-09-24 MX MX9205435A patent/MX9205435A/en unknown
- 1992-09-25 IL IL103293A patent/IL103293A0/en unknown
- 1992-09-25 JP JP4279241A patent/JPH05213939A/en active Pending
- 1992-09-28 CA CA002079268A patent/CA2079268A1/en not_active Abandoned
- 1992-09-29 AU AU26024/92A patent/AU646596B2/en not_active Expired - Fee Related
- 1992-09-29 CZ CS922976A patent/CZ297692A3/en unknown
- 1992-09-29 SK SK2976-92A patent/SK297692A3/en unknown
- 1992-09-29 FI FI924355A patent/FI924355A7/en not_active Application Discontinuation
- 1992-09-30 KR KR1019920017892A patent/KR930007937A/en not_active Withdrawn
- 1992-09-30 ZA ZA927500A patent/ZA927500B/en unknown
- 1992-10-01 HU HU9203123A patent/HUT62576A/en unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8043691A (en) *	1990-08-09	1992-02-13	Zeneca Limited	Process for the manufacture of biphenylcarbonitriles

Also Published As

Publication number	Publication date
MX9205435A (en)	1993-04-01
JPH05213939A (en)	1993-08-24
CA2079268A1 (en)	1993-04-02
HU9203123D0 (en)	1992-12-28
AU2602492A (en)	1993-04-08
CZ297692A3 (en)	1993-04-14
EP0539713A1 (en)	1993-05-05
IL103293A0 (en)	1993-02-21
DE4132632A1 (en)	1993-04-08
NO923580L (en)	1993-04-02
HUT62576A (en)	1993-05-28
ZA927500B (en)	1993-05-03
NO923580D0 (en)	1992-09-15
FI924355A0 (en)	1992-09-29
KR930007937A (en)	1993-05-20
FI924355L (en)	1993-04-02
SK297692A3 (en)	1995-09-13
TW206223B (en)	1993-05-21
FI924355A7 (en)	1993-04-02

Publication	Publication Date	Title
AU1803092A (en)	1993-01-07	7-azaisoindolinyl-quinolone- and-naphthyridonecarboxylic acid derivatives
AU1739192A (en)	1992-12-24	7-isoindolinyl-quinolone- and -naphthyridonecarboxylic acid derivatives
AU3105493A (en)	1993-07-15	Quinolone- and naphthyridone-carboxylic acid derivatives
AU1025792A (en)	1992-08-06	Amino acid derivatives
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AU667757B2 (en)	1996-04-04	Quinolone- and naphthyridonecarboxylic acid derivatives
IL103538A0 (en)	1993-03-15	Quinoxaline-carboxylic and-phosphonic acid derivatives
AU1600392A (en)	1992-11-12	Substituted carboxylic acid derivatives
AU646596B2 (en)	1994-02-24	Substituted imidazolyl-propenoic acid derivatives
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AU646762B2 (en)	1994-03-03	Cyclic-substituted imidazolyl-propenoic acid derivatives
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HU9302728D0 (en)	1993-12-28	Pyridazinone-acetic acid derivatives
AU3376993A (en)	1993-09-02	Sulphonylbenzyl-substituted imidazolylpropenoic acid derivatives
AU1153892A (en)	1992-09-07	Pyrimidinyl- and triazinylsalicyl- and -picolinylaldehyde derivatives
AU7072794A (en)	1995-02-06	2-oximino-2-thienyl-acetic acid derivatives
AU3242193A (en)	1993-07-19	Antithrombotic diaminoalkanoic acid derivatives
AU1509492A (en)	1992-10-29	Novel thienyl-nonatetraenoic acid derivatives
AU2399292A (en)	1993-03-16	Substituted acrylamido-penicillanic acid derivatives