AU655248B2 - Organic supplement containing selenium and vitamins A and E for animals - Google Patents
Organic supplement containing selenium and vitamins A and E for animals Download PDFInfo
- Publication number
- AU655248B2 AU655248B2 AU14900/92A AU1490092A AU655248B2 AU 655248 B2 AU655248 B2 AU 655248B2 AU 14900/92 A AU14900/92 A AU 14900/92A AU 1490092 A AU1490092 A AU 1490092A AU 655248 B2 AU655248 B2 AU 655248B2
- Authority
- AU
- Australia
- Prior art keywords
- supplement
- organic
- selenium
- animals
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000013589 supplement Substances 0.000 title claims description 30
- 239000011669 selenium Substances 0.000 title claims description 29
- 229910052711 selenium Inorganic materials 0.000 title claims description 29
- 235000011649 selenium Nutrition 0.000 title claims description 29
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 title claims description 25
- 241001465754 Metazoa Species 0.000 title claims description 20
- 235000019165 vitamin E Nutrition 0.000 title claims description 9
- 239000011709 vitamin E Substances 0.000 title claims description 9
- 235000019155 vitamin A Nutrition 0.000 title claims description 5
- 239000011719 vitamin A Substances 0.000 title claims description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 14
- 244000068988 Glycine max Species 0.000 claims description 9
- 235000010469 Glycine max Nutrition 0.000 claims description 9
- 239000011651 chromium Substances 0.000 claims description 9
- 239000013522 chelant Substances 0.000 claims description 8
- 229910052804 chromium Inorganic materials 0.000 claims description 8
- 235000012721 chromium Nutrition 0.000 claims description 8
- 229930003427 Vitamin E Natural products 0.000 claims description 7
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 7
- -1 selenium amino acid Chemical class 0.000 claims description 7
- 229940046009 vitamin E Drugs 0.000 claims description 7
- 241000283086 Equidae Species 0.000 claims description 6
- 102000004169 proteins and genes Human genes 0.000 claims description 6
- 108090000623 proteins and genes Proteins 0.000 claims description 6
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 5
- 229930003316 Vitamin D Natural products 0.000 claims description 5
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 5
- 229910052732 germanium Inorganic materials 0.000 claims description 5
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 claims description 5
- 235000019166 vitamin D Nutrition 0.000 claims description 5
- 239000011710 vitamin D Substances 0.000 claims description 5
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 5
- 229940046008 vitamin d Drugs 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 4
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 3
- 235000007164 Oryza sativa Nutrition 0.000 claims description 3
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 3
- 239000000835 fiber Substances 0.000 claims description 3
- 239000000945 filler Substances 0.000 claims description 3
- 235000009566 rice Nutrition 0.000 claims description 3
- 229940045997 vitamin a Drugs 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- 229920002774 Maltodextrin Polymers 0.000 claims description 2
- RJFAYQIBOAGBLC-BYPYZUCNSA-N Selenium-L-methionine Chemical compound C[Se]CC[C@H](N)C(O)=O RJFAYQIBOAGBLC-BYPYZUCNSA-N 0.000 claims description 2
- RJFAYQIBOAGBLC-UHFFFAOYSA-N Selenomethionine Natural products C[Se]CCC(N)C(O)=O RJFAYQIBOAGBLC-UHFFFAOYSA-N 0.000 claims description 2
- 150000001413 amino acids Chemical class 0.000 claims description 2
- 229960002718 selenomethionine Drugs 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- 239000003643 water by type Substances 0.000 claims description 2
- 240000007594 Oryza sativa Species 0.000 claims 2
- 241000030538 Thecla Species 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 229940107218 chromium Drugs 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
- 229940091258 selenium supplement Drugs 0.000 description 22
- 235000013734 beta-carotene Nutrition 0.000 description 4
- 239000011648 beta-carotene Substances 0.000 description 4
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 description 2
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 2
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 2
- 229960002747 betacarotene Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229960002061 ergocalciferol Drugs 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 235000001892 vitamin D2 Nutrition 0.000 description 2
- 239000011653 vitamin D2 Substances 0.000 description 2
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 101001073212 Arabidopsis thaliana Peroxidase 33 Proteins 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- 102000006587 Glutathione peroxidase Human genes 0.000 description 1
- 108700016172 Glutathione peroxidases Proteins 0.000 description 1
- 101001123325 Homo sapiens Peroxisome proliferator-activated receptor gamma coactivator 1-beta Proteins 0.000 description 1
- 241000209094 Oryza Species 0.000 description 1
- 102100028961 Peroxisome proliferator-activated receptor gamma coactivator 1-beta Human genes 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- GNBVPFITFYNRCN-UHFFFAOYSA-M sodium thioglycolate Chemical compound [Na+].[O-]C(=O)CS GNBVPFITFYNRCN-UHFFFAOYSA-M 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
k~a 655248 1-
AUSTRAL!I
PATENTS ACT 1990 CO0M P LET E S PERC IFI C A TI 0N FOR A STANDARD PATENT O R I G I NA L *,00 Name of Applicant: Actual Inventor: Address for Service: KftT-U~IE BRID)GET &Atf-IS Kathrine Bridget Davis SHELSTON WATERS Clarence Street SYDNEY NSW 2000 S~:4j4 OttO ottt Invention Title: "ORGANIC SUPPLEMENT I'Fl AHIMA COUT&I&JAJQJ .SELENIUMV #fpNt VT4MWe~S A I Jb E Fo- AAJIMAI1-S The following statement is a full description of this invention, including the best method of performing it known to me:-
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C C I' e la- The present invention relates to an organic supplement for animals, said supplement containing selenium. The supplement is more specifically for use by horses. The selenium is in a form suitable for biochemical use by the animal.
The presence of selenium in, for example, racing horses can assist oxygenation of the tissues. This in turn assists in the optimal performance of a horse at key times. The presence of selenium can also enhance other biochemical characteristics, for example increasing the efficiency of the immune system.
Selenium is known to be an element required in trace amounts by animals. However, in selenium deficient countries such as New Zealand, most known 15 methods of providing a selenium supplement in either ethical or non-ethical concentrations (as hereinafter defined) are either inefficient in their means of administration to the animal salt licks) poorly bioavailable or expensive (injection).
20 An object of the present invention is the provision of an organic supplement containing selenium for animals which is simple to administer to the animal, and also efficient in terms of the uptake of selenium by the animal. A further object of the invention is the provision of an organic supplement which can help enhance the performance of an animal under working conditions.
As used herein, the term "ethical" refers to a compound or mixture in which selenium is prit-,Oatt in a concentration of three or more parts per million (3 ppm) The term "non-ethical" refers to a compound or mixture in which selenium is present in a concentration of less than three parts per million (3ppm) This definition for the concentration of selenium in a compound may 4 t i,
A_
b~l~' Cr icr. I SC C Cii 't.
CCt Cc 2 differ from that used in any Licensed Animals Remedy Act. It is also different from that used for horses.
The present invention provides an organic supplement for animals, said supplement including: selenium in a concentration in the range 0.001 to 130 ppm, said selenium being contained in an organic form suitable for administration to animals; Vitamin E in a form suitable for administration to animals; germanium in a concentration in the range 1 milligram to 1 gram in a 15 gram dose, Vitamin A in a concentration in the range 1,000 to 3,000 i.u. in a 15 gram dose; and a base which includes bulk fillers and a flavouring.
The supplement may also include one or more of the following: chromium in a concentration in the range 0.5 milligrams to 1.5 milligrams; Vitamin D in a concentration of approximately 1,000 i.u. and Vitamin E in a concentration of approximately 500 i.u. in said dose; these concentrations being those of each component in a dose of 15 grams.
Preferably the selenium is in the form of either selenomethionine or another selenium amino acid chelate. However other organic forms of selenium could also be used.
Preferably the germanium is in the form germanium amino acid chelate, and the chromium is in the form chromium amino acid chelate. Preferably said base includes maltodextrins or a natural sugar (such as lactose or fructose), rice bran, soya fibre or a soya protein isolate and apple flavouring. Sorbitol may also be present. Soya protein isolate is preferred over soya fibre as it includes amino acids which are either essential or desirable to bodily functions.
By way of example only two examples are given of formulae for a supplement suitable for oral administration to horses.
j ":k -3 Example 1. NON-ETHICAL Selenium Amino Acid Chelate d a Tocopherol (vitamin E) Beta Carotene (provitamin A) Calciferol (vitamin D) Germanium Amino Acid Chelate Chromium Amino Acid Chelate Base: Soya Protein Isolate Rice Bran Lactose Apple Flavour o 9,,
'S
.4 t Total salt gms/100gms 0.147 3.333 0.067 0.067 0.067 0.333 19.144 38.288 38.288 0.300 Total Salt gms/100 gms 3.333 3.333 0.067 0.067 0.067 0.333 18.500 37.000 37.000 0.300 ppm 2.9 16,666 66 666 66 66 15 Example 2. ETHICAL Selenium Amino Acid Chelate d a Tocopherol (vitamin E) 20 Beta Carotene (provitamin A) Calciferol (vitamin D) Germanium Amino Acid Chelate Chromium Amino Acid Chelate Base: Soya Protein Isolate Rice Bran Lactose Apple Flavour ppm 66 16,666 66 666 66 66 rt t S S d It will be appreciated that the weight of the dose and the proportion of the components (or the relative concentrations thereof) of the supplement may be varied to suit each individual animal species. Given the above concentrations, an appropriate dose per day for a horse is 15 gms of the supplement.
Trial runs of these examples have been conducted. With the supplement of the present invention, improvements in the horses on the trial runs have been found to include: improved freedom
F-
S4 of movement; improvement in temperament; improvement in coat appearance; increased whole blood selenium and glutathione peroxidase levels. It is not known how the supplement has all of these effects, nor the manner of operation, bio-chemically, of the supplement. It is believed that the combined presence of selenium, germanium, chromium and Vitamins E and A has a synergistic effect on the individual effect of each separately.
However, this is not known to be certain. It is possible, but not certain, that the synergistic effect is caused by the combined presence of selenium in an organic form and Vitamin E.
4 t
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Claims (4)
- 4. 44 .4 C. *1 C I C 4 t1 ''CS 4 C 4, C, 54CC. ~44 THE CLA~IMS DEFINING THE INVENTION ARE AS FOLLOWS:- 1. An organic supplement for animals, said supplement including: selenium in a concentration in the range 0.001 to 130 ppm, said selenium being contained in an organic form suitable for administration to animals; Vitamin E in a form suitable for administration to animals; germanium in a concentration in the range 1 milligram to 1 gram in a 15 gram dose; Vitamin A in a concentration in the range 1,000 to 3,000 i.u. in a 10 gram dose; and a base which includes bulk fillers and a flavouring. 2. An organic supplement as claimed in claim 1 wherein the selenium is in the form of either selenomethionine or other selenium amino acid chelate. 15 3. An organic supplempult as claimed in either claim 1 or claim 2 wherein said selenium is present in an ethical concentration (as hereinbefore defined). 4. An organic supplement as claimed in any one of the preceding claims wherein said supplement includes Vitamin, E in a concentration of approximately 500 i.u. in a 15 gram dose. An organic supplement as claimed in any one of the preceding claims wherein said supplement includes chromium in a concentration in the range 0.5 milligrams to 1.5 milligrams in a 15 gram .dose.
- 6. An organic supplement as claimed in any one of the preceding claims wherein said supplement includes Vitamin D in a concentration of approximately 1,000 i.u. C. *1 I *i 1 c 6 in a 15 gram dose.
- 7. An organic supplement as claimed in any one of the preceding claims wherein said base includes soya protein isolate, rice bran, a natural sugar and apple flavouring.
- 8. An organic supplement as claimed in any one of claims 1 to 6 wherein said base includes maltodextrins, sorbitol, rice bran, soya fibre and apple flavouring. e 9. An organic supplement substantially as 10 hereinbefore described and as claimed in claim 1 and with reference to either of the Examples. DATED this 8th day of AUGUST, 1994 a KATHRINE BRIDGET DAVIS Attorney: IAN T. ERNST 15 Fellow Institute of Patent Attorneys of Australia of SHELSTON WATERS B t 'CCC t; In j; S.4 9E 7 Abstract The invention provides an organic supplement for animals, which is particularly suitable for horses, which includes selenium in a form suitable for administration to animals, vitamin E in a form suitable for administration to animals and a base which includes bulk fillers and a flavouring. The selenium is preferably in the form of an acid chelate. The bulk flavouring is preferably a soya protein isolate so that it includes amino acids that are either essential or desirable to good bodily function. Additional compounds included in the supplement are germanium, chromium, vitamin A and vitamin D. ,o 0# I 4.4 I@P 4 4 I i i :r .rr i- ,I i
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ238825 | 1991-07-03 | ||
| NZ238825A NZ238825A (en) | 1991-07-03 | 1991-07-03 | Food supplement containing selenium, germanium, and at least vitamins a and e |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1490092A AU1490092A (en) | 1993-01-07 |
| AU655248B2 true AU655248B2 (en) | 1994-12-08 |
Family
ID=19923638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU14900/92A Ceased AU655248B2 (en) | 1991-07-03 | 1992-04-14 | Organic supplement containing selenium and vitamins A and E for animals |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU655248B2 (en) |
| NZ (1) | NZ238825A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0114080A (en) * | 2000-09-22 | 2003-07-29 | Mars Uk Ltd | Dietary supplement, use thereof, method to assist in the prevention or treatment of oxidative damage, food, and methods for manufacturing the same, and to improve or increase the work output of an animal. |
| GB2385254B (en) * | 2000-09-22 | 2004-05-05 | Mars Uk Ltd | Food supplement |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0167840A1 (en) * | 1984-06-09 | 1986-01-15 | Richard Hau | Dietary composition |
| AU625600B2 (en) * | 1986-04-30 | 1992-07-16 | Union Oil Company Of California | Selenium-sulfur compositions and uses therefor |
| AU642237B2 (en) * | 1990-04-26 | 1993-10-14 | Van Epenhuysen Chemische Fabrieken B.V. | A method for preparing an aqueous food supplement for cattle and thus prepared food supplement |
-
1991
- 1991-07-03 NZ NZ238825A patent/NZ238825A/en unknown
-
1992
- 1992-04-14 AU AU14900/92A patent/AU655248B2/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0167840A1 (en) * | 1984-06-09 | 1986-01-15 | Richard Hau | Dietary composition |
| AU625600B2 (en) * | 1986-04-30 | 1992-07-16 | Union Oil Company Of California | Selenium-sulfur compositions and uses therefor |
| AU642237B2 (en) * | 1990-04-26 | 1993-10-14 | Van Epenhuysen Chemische Fabrieken B.V. | A method for preparing an aqueous food supplement for cattle and thus prepared food supplement |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ238825A (en) | 1994-03-25 |
| AU1490092A (en) | 1993-01-07 |
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