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AU669482B2 - Novel 2-amino naphthyridine derivative, its preparation and use - Google Patents
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AU669482B2 - Novel 2-amino naphthyridine derivative, its preparation and use - Google Patents

Novel 2-amino naphthyridine derivative, its preparation and use

Info

Publication number
AU669482B2
AU669482B2 AU23609/92A AU2360992A AU669482B2 AU 669482 B2 AU669482 B2 AU 669482B2 AU 23609/92 A AU23609/92 A AU 23609/92A AU 2360992 A AU2360992 A AU 2360992A AU 669482 B2 AU669482 B2 AU 669482B2
Authority
AU
Australia
Prior art keywords
preparation
novel
naphthyridine derivative
formula
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU23609/92A
Other versions
AU2360992A (en
Inventor
Marie-Therese David-Comte
Gerard Roussel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of AU2360992A publication Critical patent/AU2360992A/en
Application granted granted Critical
Publication of AU669482B2 publication Critical patent/AU669482B2/en
Assigned to AVENTIS PHARMA S.A. reassignment AVENTIS PHARMA S.A. Request to Amend Deed and Register Assignors: RHONE-POULENC RORER S.A.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

New 2-aminonaphthyridine derivative of formula: <IMAGE> its optical isomers, its salts and its preparation. The product of formula (I) is particularly useful for preparing the automer of the product of formula: <IMAGE> which exhibits notable therapeutic properties.
AU23609/92A 1991-07-12 1992-07-10 Novel 2-amino naphthyridine derivative, its preparation and use Expired AU669482B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9108827A FR2678931B1 (en) 1991-07-12 1991-07-12 NEW DERIVATIVE OF AMINO-2 NAPHTYRIDINE, ITS PREPARATION AND ITS USE.
FR9108827 1991-07-12
PCT/FR1992/000669 WO1993001190A1 (en) 1991-07-12 1992-07-10 Novel 2-amino naphthyridine derivative, its preparation and use

Publications (2)

Publication Number Publication Date
AU2360992A AU2360992A (en) 1993-02-11
AU669482B2 true AU669482B2 (en) 1996-06-13

Family

ID=9415045

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23609/92A Expired AU669482B2 (en) 1991-07-12 1992-07-10 Novel 2-amino naphthyridine derivative, its preparation and use

Country Status (18)

Country Link
EP (2) EP0598765B1 (en)
JP (1) JP2712114B2 (en)
KR (1) KR100235376B1 (en)
AT (1) ATE129499T1 (en)
AU (1) AU669482B2 (en)
CA (1) CA2112979C (en)
DE (1) DE69205685T2 (en)
DK (1) DK0598765T3 (en)
ES (1) ES2079200T3 (en)
FR (1) FR2678931B1 (en)
GR (1) GR3017889T3 (en)
IE (1) IE69386B1 (en)
IL (1) IL102443A0 (en)
MA (1) MA22586A1 (en)
MX (1) MX9204056A (en)
NZ (1) NZ243495A (en)
WO (1) WO1993001190A1 (en)
ZA (1) ZA925100B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678933B1 (en) * 1991-07-12 1993-09-24 Rhone Poulenc Rorer Sa PROCESS FOR THE PREPARATION OF OPTICAL ISOMERS OF A DERIVATIVE OF AMINO-2 NAPHTYRIDINE.
FR2678932B1 (en) * 1991-07-12 1993-09-24 Rhone Poulenc Rorer Sa PROCESS FOR THE PREPARATION OF OPTICAL ISOMERS OF A DERIVATIVE OF AMINO-2 NAPHTYRIDINE.
FR2678934B1 (en) * 1991-07-12 1995-01-13 Rhone Poulenc Rorer Sa PROCESS FOR THE PREPARATION OF THE DEXTROGYRE ISOMER OF AN ISOINDOLINONE DERIVATIVE.
IL164377A0 (en) * 2002-03-29 2005-12-18 Indevus Pharmaceuticals Inc Methods of preparation of the 2-(7-chloro-1,8-naphthyridine-2yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinone

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960779A (en) * 1986-12-02 1990-10-02 Rhone-Poulenc Sante Pyrrole derivatives, and pharmaceutical compositions which contain them and pharmacological methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313060A1 (en) * 1974-11-07 1976-12-31 Rhone Poulenc Ind Pyrrolidinone deriirrivs as tranquillizers - 1-Heterocyclyl-5(1-piperazinyl-carbonyloxy)-2(5H)-pyrrolidinone derivs prepd. from 5-aryloxycarbonyloxy cpds. and piperazine (OE060576)
FR2321290A1 (en) * 1975-04-07 1977-03-18 Rhone Poulenc Ind 1,8-naphthyridine tranquillisers, e hypnotics, anti-epileptics etc. - 2-substd. by isoindoline, pyrrolo-(3,4-b)-pyrazines, pyrrolo-(3,4-b)-pyridine or oxathino-(1,4)(2,3-c)-pyrrole

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960779A (en) * 1986-12-02 1990-10-02 Rhone-Poulenc Sante Pyrrole derivatives, and pharmaceutical compositions which contain them and pharmacological methods of use

Also Published As

Publication number Publication date
ATE129499T1 (en) 1995-11-15
IE69386B1 (en) 1996-09-18
EP0598765B1 (en) 1995-10-25
ZA925100B (en) 1993-04-28
JP2712114B2 (en) 1998-02-10
EP0522969A1 (en) 1993-01-13
DE69205685D1 (en) 1995-11-30
GR3017889T3 (en) 1996-01-31
ES2079200T3 (en) 1996-01-01
FR2678931B1 (en) 1993-09-24
WO1993001190A1 (en) 1993-01-21
CA2112979A1 (en) 1993-01-21
NZ243495A (en) 1994-11-25
MA22586A1 (en) 1993-04-01
IL102443A0 (en) 1993-01-14
JPH06509086A (en) 1994-10-13
AU2360992A (en) 1993-02-11
KR100235376B1 (en) 1999-12-15
DE69205685T2 (en) 1996-03-21
EP0598765A1 (en) 1994-06-01
FR2678931A1 (en) 1993-01-15
MX9204056A (en) 1993-01-01
DK0598765T3 (en) 1995-12-04
CA2112979C (en) 2003-09-30
IE922235A1 (en) 1993-01-13

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Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: AVENTIS PHARMA S.A.

Free format text: FORMER NAME WAS: RHONE-POULENC RORER S.A.