BE888566A - 6-(pyridinyl)-3(2h)-pyridazinones 4-substituee leur preparation, leur utilisation comme agents cardiotoniques, et composes intermediaires, - Google Patents

6-(pyridinyl)-3(2h)-pyridazinones 4-substituee leur preparation, leur utilisation comme agents cardiotoniques, et composes intermediaires,

Info

Publication number: BE888566A
Authority: BE; Belgium
Prior art keywords: pyridazinones; pyridinyl; substituted; preparation; intermediate compounds
Prior art date: 1980-04-28

Application number

BE1/10209A

Other languages

English (en)

Inventor

G Y Lesher

W B Dickinson

B Singh

Original Assignee

Sterling Drug Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-04-28

Filing date

1981-04-27

Publication date

1981-10-27

1981-04-27 Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc

1981-10-27 Publication of BE888566A publication Critical patent/BE888566A/fr

Links

FIULGFJIHJJXMT-UHFFFAOYSA-N [C]1[N]C=CC=C1 Chemical class [C]1[N]C=CC=C1 FIULGFJIHJJXMT-UHFFFAOYSA-N 0.000 title 1
239000000496 cardiotonic agent Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Cardiology (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BE1/10209A 1980-04-28 1981-04-27 6-(pyridinyl)-3(2h)-pyridazinones 4-substituee leur preparation, leur utilisation comme agents cardiotoniques, et composes intermediaires, BE888566A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/144,563 US4305943A (en)	1980-04-28	1980-04-28	4-Amino-6-(pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics

Publications (1)

Publication Number	Publication Date
BE888566A true BE888566A (fr)	1981-10-27

Family

ID=22509142

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE1/10209A BE888566A (fr)	1980-04-28	1981-04-27	6-(pyridinyl)-3(2h)-pyridazinones 4-substituee leur preparation, leur utilisation comme agents cardiotoniques, et composes intermediaires,

Country Status (7)

Country	Link
US (1)	US4305943A (fr)
JP (1)	JPS56167684A (fr)
KR (1)	KR830005203A (fr)
BE (1)	BE888566A (fr)
CA (1)	CA1166253A (fr)
PH (1)	PH16014A (fr)
ZA (1)	ZA812652B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2013097052A1 (fr)	2011-12-30	2013-07-04	Abbott Laboratories	Inhibiteurs de bromodomaine
US10208024B2 (en)	2015-10-23	2019-02-19	Array Biopharma Inc.	2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases
PT3442972T (pt)	2016-04-15	2020-05-29	Abbvie Inc	Inibidores de bromodomínio
EP3898626A1 (fr)	2018-12-19	2021-10-27	Array Biopharma, Inc.	Composés pyrazolo[1,5-a]pyridine substitués servant d'inhibiteurs de tyrosine kinases fgfr
US12351571B2 (en)	2018-12-19	2025-07-08	Array Biopharma Inc.	Substituted quinoxaline compounds as inhibitors of FGFR tyrosine kinases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4004012A (en) *	1975-10-14	1977-01-18	Sterling Drug Inc.	3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) *	1975-10-14	1978-02-07	Sterling Drug Inc.	3-Amino-5-(pyridinyl)-2(1H)-pyridinones

1980
- 1980-04-28 US US06/144,563 patent/US4305943A/en not_active Expired - Lifetime
1981
- 1981-04-22 PH PH25529A patent/PH16014A/en unknown
- 1981-04-23 ZA ZA00812652A patent/ZA812652B/xx unknown
- 1981-04-27 BE BE1/10209A patent/BE888566A/fr not_active IP Right Cessation
- 1981-04-27 KR KR1019810001437A patent/KR830005203A/ko not_active Ceased
- 1981-04-27 CA CA000376309A patent/CA1166253A/fr not_active Expired
- 1981-04-28 JP JP6510381A patent/JPS56167684A/ja active Pending

Also Published As

Publication number	Publication date
CA1166253A (fr)	1984-04-24
US4305943A (en)	1981-12-15
ZA812652B (en)	1982-05-26
PH16014A (en)	1983-05-20
KR830005203A (ko)	1983-08-03
JPS56167684A (en)	1981-12-23

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Legal Events

Date

Code

Title

Description

1984-10-31

RE

Patent lapsed

Owner name: STERLING DRUG INC.

Effective date: 19840427