DE2203379B2 - Dentifrices - Google Patents

Description

The invention relates to dental care products.

The use of surfactants with zinc salts in dentifrices is known. One Reducing the staining on the teeth as well as the tartar can be due to poorly water-soluble Zinc salts are effected. The astringent sensation caused by poorly soluble zinc salts The effect is much weaker than that which is more easily soluble with an equivalent amount Salts is evoked.

According to the present invention, the term "sparingly water-soluble zinc salt" is used as a Zinc salt of an acid understood that a higher water solubility than zinc phosphate and no greater, preferably a lower one. Has water solubility as zinc fluoride. So it is a Salt whose solubility is between that of a salt normally referred to as "insoluble" and that of a Salt with a solubility of about 1 g zinc per 100 ml water at 20 ° C.

It has been shown that when developing a In such consumer-acceptable dentifrices, taste is the real problem represents. A dentifrice that contains a poorly soluble zinc salt is somewhat astringent Taste, although this taste is not as distinct as that of a dentifrice, which is a Easily soluble zinc salt, such as zinc fluoride, contains the same amount.

It has now been found that the astringent of a dentifrice is a sparingly soluble zinc salt contains, through the use of mixtures of certain surface-active substances as surface-active Component in which dentifrice can be degraded.

The invention thus relates to a dentifrice. a sparingly soluble zinc salt / and a mixture of contains surfactants, the mixture <>? a) about 2t) to HO percent by weight of an alkyl sulfate and about HO to about 20 percent by weight an alkatyl sulfonate, or

b) about 70 to about 30 percent by weight of an alkyl sulfate and about 30 to about 70 percent by weight of an alkyl ether sulfate, or
contains a combination of these.

In particular, the invention relates to a dentifrice, which is effective against stains and tartar on the tooth surface, which is difficult to dissolve in water Zinc salt in an amount not exceeding 10 percent by weight, calculated as zinc, is an acceptable one Contains polishing agent and a mixture of sodium dodecylbenzenesulfonate and sodium lauryl sulfate.

Comparative experiments show that by no means any surface-active substance according to the invention Has an effect, some surface-active substances even potentiate the slightly astringent Effect that is caused even by poorly soluble zinc salts.

A variety of toothpastes were made containing 1.5% by weight zinc citrate and several surfactants and combinations of surfactants. The taste of the Toothpastes were tested by a group of trained testers. The results are as follows See table:

Tabel

Taste of standard toothpastes containing various surfactants:

Surface active
material

taste

1 sodium lauryl sarcosinate 0.75%
Sodium Iauryl Sulphate 0.75%

2 sodium laup I-sarcosinate 1, .1%

3 Sodium Coconut Monoglyceride Sulphate
0.75%

Sodium Iauryl Sulphate 0.75%

4 sodium sulphocolaurate 1.5%

5 sodium dioctyl sulphosuccinate 1%

6 coconut fatty acid esters of (nd)
Isethionate

7 sodium sulphoacetate

Sodium lauryl sulphate
1.0%

Sodium dodecylbenzenesulphonate 0.5%

initially uncomfortable,
It's getting worse

dry taste
develops astringency

very soapy aftertaste
pronounced
Astringency
pronounced
Astringency,
unpleasant
initially dry with development of
Astringent
no astringent,
good aftertaste, good taste

It has been shown that the sparingly soluble zinc salt which is most suitable for incorporation into a dentifrice is zinc citrate. This salt is preferably used. Further suitable zinc salts are zinc benzoate, zinc caproate, zinc carbonate, zinc fluoride, zinc lactate or zinc valcrate. Additional examples of zinc salts which fall under the definition of "sparingly soluble" used here are zinc-C1-4 alkylbenzoylacrylate, zinc-C1-4 alkyl malate. Zinkeapryliit, Zinkhcxafluorsilikat, zinc 2-hcxyl-5-chlorsalicylanilid, zinc soaps of C _H, "- fatty acids, such as zinc

Laurate, zinc octoate, zinc oleate or zinc stearate, zinc applies. This patent describes and includes

stannate, zinc silicate, zinc tannate or zinc tetrafluorine toothpastes that are a porous silica xerogel

borate. Of course, those used must have an average particle diameter of about

Zinc salts are physiologically tolerable, have 2 to about 20 μ. These substances have im

The aforementioned alkyl sulfate is preferably a 5 general surface area of at least

Alkali-C, Q_ _{! Fl} -alkyIsulfat, in particular sodium lukewarm 30OmVg, preferably from about 600 to about

ryl sulfate, 800 mVg, Contain the toothpastes described

The alkylarylsulfonate is preferably an alkali, generally 5 to 50 percent by weight of _{silicon, C, 16} -alkylbenzene or naphthalenesulfonate, in particular dioxide xerogels and can also contain 0.5 to 13% sodium dodecylbenzenesulfonate. iu weight percent of a fumed silica or

The aforementioned synthetic surface-active 0.5 to 20 percent of a silicon dioxide airgel is used Substances are made from vegetable oils and / or mixtures. The toothpastes described can be like that see made from mineral oils. In this way, the toothpastes of the invention are made transparent or traced "-Lauryl-e" or "-dodecylbenzene-" can be produced for shining.

Substances are used which are essentially mixtures. An aluminum oxide polishing agent is preferred

represent, which predominantly from C, ₂ -alkyl compounds finely divided alpha-aluminum oxide trihydrate

exist. turns. A preferred trihydrate is

The alkyl ether sulfate has a preferred grain size distribution such that at least 20 parts to an alkali-Q ^ Kj-alkyl ether sulfate with a weight percent of the particles a size of over 20 μ Average content of 1 to 3 molecules of ethylene oxide. 20 have. This polishing agent and its application

Although the niche of sodium lauryl sulfate and in dentifrices is in GB-PS 1188353 sodium lauryl ether sulfate in the same way as written. The dentifrice mixtures of sodium lauryl sulfate and sodium dodecyl agent of the invention preferably contain at least 40 percent by weight of benzene sulfonate to reduce the astringency of a polishing agent, with at least 30 percent by weight of dentifrice causing the first 25 percent of the dentifrice from the aforementioned mixtures to have poorer foaming agents. trihydrate consist,
properties. For this reason, mixtures of sodium Although some zinc salts, which come under the term of the sparingly soluble zinc salt called pre-lauryl sulfate and sodium dodecylbenzenesulfonate, are preferred. proposed as a polishing agent in dentifrice products

In the dentifrices of the invention, those 30 have been shown to have poor polishing effect.

sparingly soluble zinc compounds, preferably in large quantities of these poorly cleaning polishing agents

Quantities of 0.1 to about 10 percent by weight of the tel are not within the scope of the present invention

Dentifrice. calculated ah zinc, used. manure.

When using zinc chloride as a zinc compound in addition to a sparingly soluble zinc salt and a

quantities of about 0.25 to about 0 percent are suitable.

net. The dentifrice invention preferably also contains the usual additives. Toothpastes

about 0.5 to 5 percent by weight of a poorly soluble hold moisture-retaining substances, such as glycerin,

Zinc salt. Sorbitol or polyethylene glycols, binders, such as syn-

For the aforementioned, preferred dental care, cellulose binding agents, vegetable gums For the purposes of the invention, it is important to use one with the agent 40 or one of the aforementioned silica aerogels use a compatible polishing agent. Made of fumed or fumed silicon dioxide. Like one Druck "compatible polishing agent" denotes polishing dental care agent according to the invention in the additives, In which the zinc ions are shown in the dental care play, other additional items can also be used can remain in solution, d. i.e., it is substances such as flavorings, colorings, germicides, a polishing agent that does not contain any buffers, sweeteners or water with zinc ions in the toothpaste complex. or chelate. Polishing agents should be included. In addition, the success Phosphate-based, which contain a water-soluble phosphate, dentifrice according to the invention, enzymes. z. B. the soluble form of sodium metaphosphate, some of which have beneficial effects in the mouth are therefore included for the preferred embodiment, in particular with regard to the reduction Approximation form of the invention is not suitable. Under this 511 the tooth stain. Preferably one is used From the point of view, the dentifrice is preferably a protease, a carbohydrase or a lipase, such as completely phosphorous free. The polishing agent is pre- trypsin, chymotrypsin, papain, dextranase, anylase preferably essentially insoluble in water. Preferential or Lipase 448 (trade name), an enzyme produced from the stomach way, the aforementioned requirements for the salivary gland of the pig, the Polish also apply to the non-preferred designs available from Nutritional Biochemical Corporation application of the invention. gen can be. In particular, these enzymes

Another requirement that is preferred in the special dextranase of the invention,

polishing agents contained according to dental care products The examples illustrate the invention,
consists in the fact that it is the mechanical cleaning of the

Toothbrush supports, although of course also substances m) Example 1
with low polishing effect together with fabrics
higher polishing effect can be used.
For use in the dental care products of the
Invention particularly suitable are silicon dioxide
and aluminum oxide polishing agents. as well as mixtures
of which with plastic particles.

The polishing agent is preferably one of the Siü'-inmdinxidc described in US Pat. No. 3,53,230.

Weight percent alpha alumina trihydrate 53.00 Glycerin 27.00 Sodium dodecylbenzenesulfonate 0.90 Sodium lauryl sulfate 1.00 Carboxymethyl cellulose 0.80 Titanium dioxide 0.50 Zinc citrate 1.00

Saccharin

Formalin

Colorants and flavorings

Water, supplements too

Example 2

alpha alurainium oxide trihydrate
Glycerin

Sodium lauryl ether sulfate
Sodium lauryl sulfate

0.20

0.04

1.00

100.00

Weight percent

53.00

27.00

0.50

1.00 carboxymethyl cellulose

Titanium dioxide

Zinc fat

Saccharin

Formalin

Coloring and flavoring substances added to water

0.80 0.50 1.00 0.20 0.04 1.00 1 (KJ ₁ OO

The dentifrices of the aforementioned examples have a less astringent taste κι as similar dentifrices that contain sodium lauryl sulfate as the only surface-active ingredient.

Claims (3)

Claims; 1. Dentifrices that contain a sparingly water-soluble zinc salt and a surfactant contain, characterized in that the dentifrice against stains and tartar is effective on the tooth surface and the surfactant a) 20 to 80 percent by weight of an alkyl sulfate in and 80 to 20 percent of an alkaryl sulfonate, or b) 70 to 30 percent by weight of an alkyl sulfate and 30 to 70 percent of an alkyl ether sulfate, or contains a combination of these. 2. Dentifrice according to claim 1, characterized in that the alkyl sulfate is sodium auryl sulfate is. 3. Dental care product according to claim 1 or 2, 2 » characterized in that the alkaryl sulfonate is sodium dodecylbenzenesulfonate.