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DE3582905D1 - Stabile liposome mit wasserloeslichen arzneimitteln. - Google Patents
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DE3582905D1 - Stabile liposome mit wasserloeslichen arzneimitteln. - Google Patents

Stabile liposome mit wasserloeslichen arzneimitteln.

Info

Publication number
DE3582905D1
DE3582905D1 DE8585305672T DE3582905T DE3582905D1 DE 3582905 D1 DE3582905 D1 DE 3582905D1 DE 8585305672 T DE8585305672 T DE 8585305672T DE 3582905 T DE3582905 T DE 3582905T DE 3582905 D1 DE3582905 D1 DE 3582905D1
Authority
DE
Germany
Prior art keywords
water
medicinal products
soluble medicinal
stable liposome
liposome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585305672T
Other languages
English (en)
Inventor
Philip L Felgner
Deborah A Eppstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Application granted granted Critical
Publication of DE3582905D1 publication Critical patent/DE3582905D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8585305672T 1984-08-10 1985-08-09 Stabile liposome mit wasserloeslichen arzneimitteln. Expired - Lifetime DE3582905D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63963884A 1984-08-10 1984-08-10
US73972985A 1985-05-31 1985-05-31

Publications (1)

Publication Number Publication Date
DE3582905D1 true DE3582905D1 (de) 1991-06-27

Family

ID=27093370

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585305672T Expired - Lifetime DE3582905D1 (de) 1984-08-10 1985-08-09 Stabile liposome mit wasserloeslichen arzneimitteln.

Country Status (2)

Country Link
EP (1) EP0172007B1 (de)
DE (1) DE3582905D1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090406A (en) * 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
US5916588A (en) * 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
FR2597367B1 (fr) * 1986-04-22 1988-07-15 Oreal Procede pour faciliter la formation de spherules lipidiques en dispersion dans une phase aqueuse et pour ameliorer leur stabilite et leur taux d'encapsulation, et dispersions correspondantes.
IE63869B1 (en) * 1986-11-06 1995-06-14 Res Dev Foundation Aerosols containing liposomes and method for their preparation
ATE118348T1 (de) * 1987-12-04 1995-03-15 Liposome Co Inc Liposome hoher stabilität und verfahren zur herstellung und verwendung.
KR900700079A (ko) * 1988-01-12 1990-08-11 후지하라 도미오 누출방지 리포좀 제제
ATE147633T1 (de) * 1988-10-27 1997-02-15 Univ Minnesota Immunhilfsmittel aus liposome enthaltend lymphokin il -2
DE3916595A1 (de) * 1989-05-22 1990-11-29 Boehringer Mannheim Gmbh Verfahren zur nichtradioaktiven messung der nucleinsaeuresynthese in eukaryontischen zellen
CA2063273C (en) * 1989-07-11 2002-09-24 Bradley J. Benson Surfactant compositions and methods
CA2038945A1 (en) * 1989-08-01 1991-02-02 Norman D. Weiner Topical delivery of peptides/proteins entrapped in dehydration/rehydration liposomes
DE4121388A1 (de) * 1991-02-07 1992-08-13 Nattermann A & Cie Pharmazeutisches produkt zur behandlung von viruserkrankungen
DE4121389A1 (de) * 1991-02-07 1992-08-13 Nattermann A & Cie Pharmazeutisches produkt zur behandlung von viruserkrankungen
CA2127107C (en) * 1991-12-31 2007-06-19 Bruce L. A. Carter Methods and compositions for reducing blood loss
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
GB9320668D0 (en) 1993-10-07 1993-11-24 Secr Defence Liposomes containing particulare materials
ATE164515T1 (de) 1993-11-05 1998-04-15 Amgen Inc Herstellung von liposomen und verfahren zur substanzverkapselung
CN1049576C (zh) * 1994-01-27 2000-02-23 武汉中科康益生物制药厂 硬质多孔松泡体栓及其制造工艺
CN1138533C (zh) 1996-09-13 2004-02-18 利普森有限公司 脂质体
US7384923B2 (en) 1999-05-14 2008-06-10 Lipoxen Technologies Limited Liposomes
AU2002311617A1 (en) * 2001-06-25 2003-01-08 The Regents Of The University Of California Method for preparation of vesicles loaded with immunostimulatory oligodeoxynucleotides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
US4186183A (en) * 1978-03-29 1980-01-29 The United States Of America As Represented By The Secretary Of The Army Liposome carriers in chemotherapy of leishmaniasis

Also Published As

Publication number Publication date
EP0172007A2 (de) 1986-02-19
EP0172007B1 (de) 1991-05-22
EP0172007A3 (en) 1987-08-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee