ES453787A1 - Un procedimiento para la preparacion de compuestos de nido- lina. - Google Patents
Un procedimiento para la preparacion de compuestos de nido- lina.Info
- Publication number
- ES453787A1 ES453787A1 ES453787A ES453787A ES453787A1 ES 453787 A1 ES453787 A1 ES 453787A1 ES 453787 A ES453787 A ES 453787A ES 453787 A ES453787 A ES 453787A ES 453787 A1 ES453787 A1 ES 453787A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- compounds
- nido
- lina
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Un procedimiento para la preparación de compuestos de indolina, de fórmula: **(Fórmula)** y de sus sales ácidas de adición farmacéuticamente aceptables, en la cual: X es flúor, cloro, bromo, metilo o hidrógeno; Z es flúor, cloro, metoxi o hidrógeno; n es 1 o 2 y R es un alquilo que contiene de 1 a 6 átomos de carbono, bencilo o un alquileno substituido.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45664074A | 1974-04-01 | 1974-04-01 | |
| US456641A US3925409A (en) | 1974-04-01 | 1974-04-01 | 4-Aryl-1,2,3,4-tetrahydropyrrolo{8 3,4-b{9 indoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES453787A1 true ES453787A1 (es) | 1978-01-01 |
Family
ID=27038317
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES436157A Expired ES436157A1 (es) | 1974-04-01 | 1975-03-31 | Un procedimiento para la preparacion de compuestos de indo- lina. |
| ES453787A Expired ES453787A1 (es) | 1974-04-01 | 1976-11-30 | Un procedimiento para la preparacion de compuestos de nido- lina. |
| ES453788A Expired ES453788A1 (es) | 1974-04-01 | 1976-11-30 | Un procedimiento para la preparacion de compuestos de nido- lina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES436157A Expired ES436157A1 (es) | 1974-04-01 | 1975-03-31 | Un procedimiento para la preparacion de compuestos de indo- lina. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES453788A Expired ES453788A1 (es) | 1974-04-01 | 1976-11-30 | Un procedimiento para la preparacion de compuestos de nido- lina. |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS587635B2 (es) |
| AR (2) | AR207799A1 (es) |
| AU (1) | AU7955975A (es) |
| DD (1) | DD118879A5 (es) |
| DE (1) | DE2514084A1 (es) |
| DK (2) | DK130575A (es) |
| ES (3) | ES436157A1 (es) |
| FI (1) | FI750940A7 (es) |
| FR (1) | FR2265368A1 (es) |
| IL (1) | IL46925A0 (es) |
| LU (1) | LU72182A1 (es) |
| NL (1) | NL7503700A (es) |
| NO (1) | NO751055L (es) |
| RO (1) | RO72884A (es) |
| SE (2) | SE423630B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224329A (en) * | 1979-01-23 | 1980-09-23 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| US4451655A (en) * | 1982-05-17 | 1984-05-29 | Pfizer Inc. | Process for preparing carboline derivatives and compounds used in their preparation |
| AU765751B2 (en) * | 1998-12-21 | 2003-09-25 | Janssen Pharmaceutica N.V. | Benzisoxazoles and phenones as alpha2-antagonists |
| RU2320662C1 (ru) * | 2006-08-24 | 2008-03-27 | Андрей Александрович Иващенко | ЗАМЕЩЕННЫЕ ПИРРОЛО[4,3-b]ИНДОЛЫ, КОМБИНАТОРНАЯ И ФОКУСИРОВАННАЯ БИБЛИОТЕКИ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ |
| CA2796756A1 (en) * | 2010-04-22 | 2011-10-27 | Intra-Cellular Therapies, Inc. | Substituted pyrido(3',4':4,5)pyrrolo(1,2,3-de)quinoxalines for the treatment of central nervous system disorders |
-
1975
- 1975-01-01 AR AR261449A patent/AR207799A1/es active
- 1975-01-01 AR AR258188A patent/AR206812A1/es active
- 1975-03-14 SE SE7502927A patent/SE423630B/xx unknown
- 1975-03-25 IL IL46925A patent/IL46925A0/xx unknown
- 1975-03-25 NO NO751055A patent/NO751055L/no unknown
- 1975-03-26 DK DK130575A patent/DK130575A/da not_active Application Discontinuation
- 1975-03-26 AU AU79559/75A patent/AU7955975A/en not_active Expired
- 1975-03-27 NL NL7503700A patent/NL7503700A/xx not_active Application Discontinuation
- 1975-03-27 FI FI750940A patent/FI750940A7/fi not_active Application Discontinuation
- 1975-03-29 DE DE19752514084 patent/DE2514084A1/de not_active Ceased
- 1975-03-31 ES ES436157A patent/ES436157A1/es not_active Expired
- 1975-04-01 JP JP50040224A patent/JPS587635B2/ja not_active Expired
- 1975-04-01 FR FR7510139A patent/FR2265368A1/fr active Granted
- 1975-04-01 LU LU72182A patent/LU72182A1/xx unknown
- 1975-04-01 DD DD185114A patent/DD118879A5/xx unknown
- 1975-04-01 RO RO7581868A patent/RO72884A/ro unknown
-
1976
- 1976-11-30 ES ES453787A patent/ES453787A1/es not_active Expired
- 1976-11-30 ES ES453788A patent/ES453788A1/es not_active Expired
-
1978
- 1978-05-01 DK DK187878A patent/DK187878A/da not_active Application Discontinuation
-
1982
- 1982-01-07 SE SE8200047A patent/SE8200047L/sv not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES436157A1 (es) | 1977-04-16 |
| AU7955975A (en) | 1976-09-30 |
| AR206812A1 (es) | 1976-08-23 |
| SE8200047L (sv) | 1982-01-07 |
| IL46925A0 (en) | 1975-05-22 |
| AR207799A1 (es) | 1976-10-29 |
| FI750940A7 (es) | 1975-10-02 |
| DD118879A5 (es) | 1976-03-20 |
| SE7502927L (es) | 1975-10-02 |
| FR2265368A1 (en) | 1975-10-24 |
| DE2514084A1 (de) | 1975-11-20 |
| NL7503700A (nl) | 1975-10-03 |
| JPS587635B2 (ja) | 1983-02-10 |
| JPS50140494A (es) | 1975-11-11 |
| DK130575A (es) | 1975-10-02 |
| DK187878A (da) | 1978-05-01 |
| ES453788A1 (es) | 1978-01-01 |
| RO72884A (ro) | 1983-08-03 |
| RO72884B (ro) | 1983-07-30 |
| LU72182A1 (es) | 1976-03-02 |
| FR2265368B1 (es) | 1978-07-28 |
| SE423630B (sv) | 1982-05-17 |
| NO751055L (es) | 1975-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19981103 |