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ES8405619A1 - Procedimiento de preparacion de nuevas n-(5-aminometil 2-oxazolin 2-il)-n'-fenilureas - Google Patents
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ES8405619A1 - Procedimiento de preparacion de nuevas n-(5-aminometil 2-oxazolin 2-il)-n'-fenilureas - Google Patents

Procedimiento de preparacion de nuevas n-(5-aminometil 2-oxazolin 2-il)-n'-fenilureas

Info

Publication number
ES8405619A1
ES8405619A1 ES526276A ES526276A ES8405619A1 ES 8405619 A1 ES8405619 A1 ES 8405619A1 ES 526276 A ES526276 A ES 526276A ES 526276 A ES526276 A ES 526276A ES 8405619 A1 ES8405619 A1 ES 8405619A1
Authority
ES
Spain
Prior art keywords
alkyl radical
aminomethyl
carbocyclic
radical
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526276A
Other languages
English (en)
Other versions
ES526276A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortial SA
Original Assignee
Cortial SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8216783A external-priority patent/FR2533923A1/fr
Priority claimed from FR8313013A external-priority patent/FR2550198B2/fr
Application filed by Cortial SA filed Critical Cortial SA
Publication of ES8405619A1 publication Critical patent/ES8405619A1/es
Publication of ES526276A0 publication Critical patent/ES526276A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE N-(5-AMINOMETIL 2-OXAZOLIN 2-IL)-N-FENILUREAS, DE FORMULA GENERAL (I), EN LA QUE R1 Y R2 REPRESENTAN UN RADICAL ALQUILO, ARILALQUIL O ARIL, O TAMBIEN R1 Y R2 PUEDEN FORMAR CON EL ATOMO AL CUAL ESTAN UNIDOS, UN HETEROCICLO TAL COMO PIPERIDINA, PIRROLIDINA, MORFOLINA O PIPERIDINA.CONSISTE EN HACER REACCIONAR EN UN SOLVENTE, A LA TEMPERATURA DE EBULLICION DE DICHO SOLVENTE, UN ISOCIANATO DE FENILO CON UN DERIVADO DE FORMULA GENERAL (II), EN LA QUE R1 Y R2 SIGNIFICAN UN RADICAL ALQUIL.DE APLICACION EN TERAPEUTICA HUMANAY ANIMAL.
ES526276A 1982-10-05 1983-10-05 Procedimiento de preparacion de nuevas n-(5-aminometil 2-oxazolin 2-il)-n'-fenilureas Granted ES526276A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8216783A FR2533923A1 (fr) 1982-10-05 1982-10-05 Nouvelles n-(aminomethyl-5 oxazolin-2 yl-2) n'-phenylurees, leur methode de preparation ainsi que leur application therapeutique
FR8313013A FR2550198B2 (fr) 1983-08-04 1983-08-04 Nouvelles n-(aminomethyl-5 oxazolin-2yl-2)n'-phenylurees, leur methode de preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
ES8405619A1 true ES8405619A1 (es) 1984-06-16
ES526276A0 ES526276A0 (es) 1984-06-16

Family

ID=26223094

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526276A Granted ES526276A0 (es) 1982-10-05 1983-10-05 Procedimiento de preparacion de nuevas n-(5-aminometil 2-oxazolin 2-il)-n'-fenilureas

Country Status (6)

Country Link
US (1) US4499090A (es)
EP (1) EP0105821B1 (es)
DE (1) DE3362332D1 (es)
ES (1) ES526276A0 (es)
OA (1) OA08298A (es)
PT (1) PT77429B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912120A (en) * 1986-03-14 1990-03-27 Syntex (U.S.A.) Inc. 3,5-substituted 4,5-dihydroisoxazoles as transglutaminase inhibitors
US4929630A (en) * 1986-03-14 1990-05-29 Syntex (U.S.A.) Inc. Transglutaminase inhibitors
FR2615190B1 (fr) * 1987-05-14 1989-07-21 Cortial Nouvelles arylcarbamoyl-3 aminomethyl-5 oxazolidines ainsi que leurs sels avec des acides pharmaceutiquement compatibles, leur methode de preparation et leur application pharmaceutique
FR2631029B2 (fr) * 1987-05-14 1991-04-05 Cortial Nouvelles arylcarbamoyl-3 aminomethyl-5 oxazolidines ainsi que leurs sels avec des acides pharmacologiquement compatibles
GB9720052D0 (en) * 1997-09-19 1997-11-19 Smithkline Beecham Plc Novel compounds
EP1288841A1 (en) 2001-08-30 2003-03-05 Motorola, Inc. Passive response communication system
US6846838B2 (en) * 2002-06-19 2005-01-25 Bristol-Myers Squibb Company Ureido-substituted aniline compounds useful as serine protease inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1302662B (es) * 1971-02-04
DE1445583A1 (de) * 1960-10-13 1969-06-04 Albert Ag Chem Werke Verfahren zur Herstellung von Derivaten des 5-Chlormethyl-oxazolidins
DE1445581A1 (de) * 1960-10-13 1969-06-04 Albert Ag Chem Werke N-[5-Methyloxazolinyl-(2)]-N'-aryl-Harnstoffderivate und Verfahren zu deren Herstellung
US3481950A (en) * 1967-06-28 1969-12-02 Abbott Lab Substituted (4 - oxo-2-oxazolidinylidene) urea derivatives

Also Published As

Publication number Publication date
DE3362332D1 (de) 1986-04-03
OA08298A (fr) 1987-10-31
US4499090A (en) 1985-02-12
EP0105821B1 (fr) 1986-02-26
PT77429B (fr) 1986-02-27
EP0105821A1 (fr) 1984-04-18
PT77429A (fr) 1983-10-01
ES526276A0 (es) 1984-06-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203