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FR2571383B2 - IMPROVEMENT IN THE FACTOR IX PREPARATION PROCESS FROM CULTIVATIONS OF MAMMALIAN CELLS - Google Patents
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FR2571383B2 - IMPROVEMENT IN THE FACTOR IX PREPARATION PROCESS FROM CULTIVATIONS OF MAMMALIAN CELLS - Google Patents

IMPROVEMENT IN THE FACTOR IX PREPARATION PROCESS FROM CULTIVATIONS OF MAMMALIAN CELLS

Info

Publication number
FR2571383B2
FR2571383B2 FR8415294A FR8415294A FR2571383B2 FR 2571383 B2 FR2571383 B2 FR 2571383B2 FR 8415294 A FR8415294 A FR 8415294A FR 8415294 A FR8415294 A FR 8415294A FR 2571383 B2 FR2571383 B2 FR 2571383B2
Authority
FR
France
Prior art keywords
cultivations
factor
improvement
preparation process
mammalian cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8415294A
Other languages
French (fr)
Other versions
FR2571383A2 (en
Inventor
Henri De La Salle
Robert Drillien
Werner Altenburger
Paul Toltoshev
Jean-Pierre Lecocq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA filed Critical Transgene SA
Priority to FR8415294A priority Critical patent/FR2571383B2/en
Priority to EP85400999A priority patent/EP0162782B1/en
Priority to JP60502263A priority patent/JPH082307B2/en
Priority to DE8585400999T priority patent/DE3576360D1/en
Priority to AT85400999T priority patent/ATE50793T1/en
Priority to PCT/FR1985/000124 priority patent/WO1985005376A1/en
Priority to CA000482034A priority patent/CA1262877A/en
Publication of FR2571383A2 publication Critical patent/FR2571383A2/en
Application granted granted Critical
Publication of FR2571383B2 publication Critical patent/FR2571383B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR8415294A 1984-05-22 1984-10-05 IMPROVEMENT IN THE FACTOR IX PREPARATION PROCESS FROM CULTIVATIONS OF MAMMALIAN CELLS Expired FR2571383B2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR8415294A FR2571383B2 (en) 1984-10-05 1984-10-05 IMPROVEMENT IN THE FACTOR IX PREPARATION PROCESS FROM CULTIVATIONS OF MAMMALIAN CELLS
EP85400999A EP0162782B1 (en) 1984-05-22 1985-05-21 Expression vectors for factor ix, and cell lines producing the active factor ix
JP60502263A JPH082307B2 (en) 1984-05-22 1985-05-21 Method for producing factor IX
DE8585400999T DE3576360D1 (en) 1984-05-22 1985-05-21 EXPRESSION VECTORS FOR FACTOR IX AND ACTION FACTOR IX PRODUCING CELL LINES.
AT85400999T ATE50793T1 (en) 1984-05-22 1985-05-21 EXPRESSION VECTORS FOR FACTOR IX AND ACTION FACTOR IX PRODUCING CELL LINES.
PCT/FR1985/000124 WO1985005376A1 (en) 1984-05-22 1985-05-21 Vectors for the expression of factor ix and cell lineages producing the active factor ix
CA000482034A CA1262877A (en) 1984-05-22 1985-05-22 Expression vector of factor ix and cell line producing the active factor ix

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8415294A FR2571383B2 (en) 1984-10-05 1984-10-05 IMPROVEMENT IN THE FACTOR IX PREPARATION PROCESS FROM CULTIVATIONS OF MAMMALIAN CELLS

Publications (2)

Publication Number Publication Date
FR2571383A2 FR2571383A2 (en) 1986-04-11
FR2571383B2 true FR2571383B2 (en) 1989-10-06

Family

ID=9308365

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8415294A Expired FR2571383B2 (en) 1984-05-22 1984-10-05 IMPROVEMENT IN THE FACTOR IX PREPARATION PROCESS FROM CULTIVATIONS OF MAMMALIAN CELLS

Country Status (1)

Country Link
FR (1) FR2571383B2 (en)

Also Published As

Publication number Publication date
FR2571383A2 (en) 1986-04-11

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