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GB2155477B - Tricyclic aliphatic diones for use in preparing 19-norandrostenedione - Google Patents
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GB2155477B - Tricyclic aliphatic diones for use in preparing 19-norandrostenedione - Google Patents

Tricyclic aliphatic diones for use in preparing 19-norandrostenedione

Info

Publication number
GB2155477B
GB2155477B GB08508480A GB8508480A GB2155477B GB 2155477 B GB2155477 B GB 2155477B GB 08508480 A GB08508480 A GB 08508480A GB 8508480 A GB8508480 A GB 8508480A GB 2155477 B GB2155477 B GB 2155477B
Authority
GB
United Kingdom
Prior art keywords
norandrostenedione
diones
preparing
tricyclic aliphatic
tricyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08508480A
Other versions
GB2155477A (en
GB8508480D0 (en
Inventor
Joel Edward Huber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/302,004 external-priority patent/US4400524A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to GB08508480A priority Critical patent/GB2155477B/en
Publication of GB8508480D0 publication Critical patent/GB8508480D0/en
Publication of GB2155477A publication Critical patent/GB2155477A/en
Application granted granted Critical
Publication of GB2155477B publication Critical patent/GB2155477B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126Acids containing more than four carbon atoms
    • C07C53/128Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/80Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings
    • C07C59/82Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings the keto group being part of a ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Steroid Compounds (AREA)
GB08508480A 1981-07-28 1985-04-01 Tricyclic aliphatic diones for use in preparing 19-norandrostenedione Expired GB2155477B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08508480A GB2155477B (en) 1981-07-28 1985-04-01 Tricyclic aliphatic diones for use in preparing 19-norandrostenedione

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US28795581A 1981-07-28 1981-07-28
US06/302,004 US4400524A (en) 1981-07-28 1981-09-15 Grignard reagents prepared from 5-halopentan-2-one propylene ketals
GB08205712A GB2116165B (en) 1981-07-28 1982-02-26 Preparing 19-norandrostenedione and novel intermediates therefor
NL8201083A NL8201083A (en) 1981-07-28 1982-03-16 PROCESS FOR PREPARING 19-NORANDROSTEENDION.
FR8204894A FR2523977A1 (en) 1981-07-28 1982-03-23 METHOD AND KEY INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF 19-NORANDROSTENEDIONE
GB08508480A GB2155477B (en) 1981-07-28 1985-04-01 Tricyclic aliphatic diones for use in preparing 19-norandrostenedione

Publications (3)

Publication Number Publication Date
GB8508480D0 GB8508480D0 (en) 1985-05-09
GB2155477A GB2155477A (en) 1985-09-25
GB2155477B true GB2155477B (en) 1986-05-08

Family

ID=27546344

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08508480A Expired GB2155477B (en) 1981-07-28 1985-04-01 Tricyclic aliphatic diones for use in preparing 19-norandrostenedione

Country Status (1)

Country Link
GB (1) GB2155477B (en)

Also Published As

Publication number Publication date
GB2155477A (en) 1985-09-25
GB8508480D0 (en) 1985-05-09

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee