GB2201676B - Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it - Google Patents

Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it

Info

Publication number: GB2201676B
Authority: GB; United Kingdom
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; piperazinecarboxylic acid; piperazinecarboxylic
Prior art date: 1987-02-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

GB8803438A

Other versions

GB2201676A (en

GB8803438D0 (en

Inventor

Bernhard Aebischer

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-18

Filing date

1988-02-15

Publication date

1991-01-02

1988-02-15 Application filed by Sandoz AG filed Critical Sandoz AG

1988-03-16 Publication of GB8803438D0 publication Critical patent/GB8803438D0/en

1988-09-07 Publication of GB2201676A publication Critical patent/GB2201676A/en

1991-01-02 Application granted granted Critical

1991-01-02 Publication of GB2201676B publication Critical patent/GB2201676B/en

2008-02-15 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
RFIOZSIHFNEKFF-UHFFFAOYSA-N piperazine-1-carboxylic acid Chemical compound OC(=O)N1CCNCC1 RFIOZSIHFNEKFF-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

GB8803438A 1987-02-18 1988-02-15 Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it Expired - Lifetime GB2201676B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB878703749A GB8703749D0 (en)	1987-02-18	1987-02-18	Piperazinecarboxylic acid

Publications (3)

Publication Number	Publication Date
GB8803438D0 GB8803438D0 (en)	1988-03-16
GB2201676A GB2201676A (en)	1988-09-07
GB2201676B true GB2201676B (en)	1991-01-02

Family

ID=10612501

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
GB878703749A Pending GB8703749D0 (en)	1987-02-18	1987-02-18	Piperazinecarboxylic acid
GB8803438A Expired - Lifetime GB2201676B (en)	1987-02-18	1988-02-15	Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
GB878703749A Pending GB8703749D0 (en)	1987-02-18	1987-02-18	Piperazinecarboxylic acid

Country Status (28)

Country	Link
JP (1)	JPH0723387B2 (en)
KR (1)	KR960015190B1 (en)
AT (1)	AT391320B (en)
AU (1)	AU613009B2 (en)
BE (1)	BE1002427A3 (en)
CA (1)	CA1327799C (en)
CH (1)	CH675125A5 (en)
CY (1)	CY1739A (en)
DE (1)	DE3804936C2 (en)
DK (1)	DK168441B1 (en)
ES (2)	ES2011319A6 (en)
FI (1)	FI86733C (en)
FR (1)	FR2610932B1 (en)
GB (2)	GB8703749D0 (en)
GR (1)	GR1002471B (en)
HK (1)	HK142093A (en)
HU (2)	HU199858B (en)
IE (1)	IE59098B1 (en)
IL (1)	IL85436A0 (en)
IT (1)	IT1219447B (en)
LU (1)	LU87129A1 (en)
MY (1)	MY103206A (en)
NL (1)	NL8800412A (en)
NZ (1)	NZ223529A (en)
PH (1)	PH25512A (en)
PT (1)	PT86776B (en)
SE (1)	SE467256B (en)
ZA (1)	ZA881146B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US12318358B2 (en)	2017-07-13	2025-06-03	Paris Sciences Et Lettres	Probenecid for use in treating epileptic diseases, disorders or conditions

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU202111B (en) *	1988-03-11	1991-02-28	Sandoz Ag	Process for producing pharmaceutical compositions containing (r)-(e)-4--(3-phosphono-2-propenyl)-2-piperazine-carboxylic acid as active component
US5086072A (en) *	1990-06-18	1992-02-04	The United States Of America As Represented By The Department Of Health And Human Services	Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
EP0488959A3 (en) *	1990-11-28	1992-08-05	Sandoz Ltd.	New uses of competitive nmda receptor antagonists
US5260286A (en) *	1992-10-16	1993-11-09	Japan Tobacco, Inc.	2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists
AU5693996A (en) *	1995-05-08	1996-11-29	Lonza A.G.	Biotechnical production process of piperazine r-alpha-carbox ylic acids and piperazine s-alpha-carboxylic acid amide
JP4189867B2 (en)	1997-05-12	2008-12-03	オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド	Aryl-substituted piperazines useful in the treatment of benign prostatic hyperplasia
GB9821179D0 (en) *	1998-09-30	1998-11-25	Merck Sharp & Dohme	Therapeutic use
JP2008124531A (en)	2006-11-08	2008-05-29	Nec Electronics Corp	Semiconductor device and audio processor chip

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2157685A (en) *	1984-04-17	1985-10-30	Nat Res Dev	Piperazine derivatives

1987
- 1987-02-18 GB GB878703749A patent/GB8703749D0/en active Pending
1988
- 1988-02-11 LU LU87129A patent/LU87129A1/en unknown
- 1988-02-12 BE BE8800177A patent/BE1002427A3/en active
- 1988-02-12 FR FR888801782A patent/FR2610932B1/en not_active Expired - Lifetime
- 1988-02-12 IT IT47631/88A patent/IT1219447B/en active
- 1988-02-15 MY MYPI88000155A patent/MY103206A/en unknown
- 1988-02-15 GB GB8803438A patent/GB2201676B/en not_active Expired - Lifetime
- 1988-02-16 HU HU88746A patent/HU199858B/en not_active IP Right Cessation
- 1988-02-16 IL IL85436A patent/IL85436A0/en not_active IP Right Cessation
- 1988-02-16 IE IE41388A patent/IE59098B1/en not_active IP Right Cessation
- 1988-02-16 PH PH36514A patent/PH25512A/en unknown
- 1988-02-16 DK DK079688A patent/DK168441B1/en not_active IP Right Cessation
- 1988-02-16 NZ NZ223529A patent/NZ223529A/en unknown
- 1988-02-16 GR GR880100084A patent/GR1002471B/en not_active IP Right Cessation
- 1988-02-16 CH CH549/88A patent/CH675125A5/de not_active IP Right Cessation
- 1988-02-16 AU AU11758/88A patent/AU613009B2/en not_active Ceased
- 1988-02-16 CA CA000559170A patent/CA1327799C/en not_active Expired - Fee Related
- 1988-02-17 PT PT86776A patent/PT86776B/en not_active IP Right Cessation
- 1988-02-17 JP JP63036458A patent/JPH0723387B2/en not_active Expired - Lifetime
- 1988-02-17 AT AT0036788A patent/AT391320B/en not_active IP Right Cessation
- 1988-02-17 FI FI880744A patent/FI86733C/en not_active IP Right Cessation
- 1988-02-17 SE SE8800541A patent/SE467256B/en not_active IP Right Cessation
- 1988-02-17 KR KR1019880001680A patent/KR960015190B1/en not_active Expired - Fee Related
- 1988-02-17 DE DE3804936A patent/DE3804936C2/en not_active Expired - Fee Related
- 1988-02-18 ZA ZA881146A patent/ZA881146B/en unknown
- 1988-02-18 NL NL8800412A patent/NL8800412A/en not_active Application Discontinuation
- 1988-02-18 ES ES888800466A patent/ES2011319A6/en not_active Expired - Lifetime
1989
- 1989-10-16 ES ES8903482A patent/ES2021904A6/en not_active Expired - Lifetime
1993
- 1993-12-30 HK HK1420/93A patent/HK142093A/en not_active IP Right Cessation
1995
- 1995-06-09 HU HU95P/P00176P patent/HU211269A9/en unknown
- 1995-10-20 CY CY173995A patent/CY1739A/en unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2157685A (en) *	1984-04-17	1985-10-30	Nat Res Dev	Piperazine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US12318358B2 (en)	2017-07-13	2025-06-03	Paris Sciences Et Lettres	Probenecid for use in treating epileptic diseases, disorders or conditions

Also Published As

Publication number	Publication date
BE1002427A3 (en)	1991-02-05
IE880413L (en)	1988-08-18
ES2011319A6 (en)	1990-01-01
DK79688A (en)	1988-08-19
SE467256B (en)	1992-06-22
AU613009B2 (en)	1991-07-25
NZ223529A (en)	1991-02-26
HU211269A9 (en)	1995-11-28
IE59098B1 (en)	1994-01-12
FI86733B (en)	1992-06-30
ES2021904A6 (en)	1991-11-16
KR960015190B1 (en)	1996-11-01
FI880744A0 (en)	1988-02-17
LU87129A1 (en)	1988-09-20
HK142093A (en)	1994-01-07
PH25512A (en)	1991-07-24
IL85436A (en)	1992-12-01
JPH0723387B2 (en)	1995-03-15
NL8800412A (en)	1988-09-16
PT86776B (en)	1992-05-29
FI86733C (en)	1992-10-12
PT86776A (en)	1988-03-01
AT391320B (en)	1990-09-25
GB2201676A (en)	1988-09-07
DE3804936C2 (en)	1997-02-13
SE8800541D0 (en)	1988-02-17
KR880009944A (en)	1988-10-06
CH675125A5 (en)	1990-08-31
CY1739A (en)	1995-10-20
ATA36788A (en)	1990-03-15
DE3804936A1 (en)	1988-09-01
GB8803438D0 (en)	1988-03-16
FI880744L (en)	1988-08-19
GR1002471B (en)	1996-11-15
IT1219447B (en)	1990-05-18
IL85436A0 (en)	1988-07-31
FR2610932A1 (en)	1988-08-19
HUT49361A (en)	1989-09-28
GB8703749D0 (en)	1987-03-25
HU199858B (en)	1990-03-28
MY103206A (en)	1993-05-29
FR2610932B1 (en)	1990-11-16
DK168441B1 (en)	1994-03-28
JPS63203691A (en)	1988-08-23
DK79688D0 (en)	1988-02-16
GR880100084A (en)	1988-12-16
ZA881146B (en)	1989-10-25
AU1175888A (en)	1988-08-25
IT8847631A0 (en)	1988-02-12
CA1327799C (en)	1994-03-15

Legal Events

Date	Code	Title	Description
1997-06-25	732E	Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
2003-10-08	PCNP	Patent ceased through non-payment of renewal fee

Publication	Publication Date	Title
IL76453A (en)	1989-01-31	Isoxazolecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL84723A0 (en)	1988-05-31	Substituted basic 2-amino-tetralins,their preparation and pharmaceutical compositions containing them
IL81322A0 (en)	1987-08-31	Thieno-1,4-diazepines,their preparation and pharmaceutical compositions containing them
IL84302A (en)	1993-06-10	Substituted :-aminoacids, their preparation and pharmaceutical compositions containing them
IL84060A0 (en)	1988-03-31	Imidazobenzoxazinones,their preparation and pharmaceutical compositions containing them
IL78942A0 (en)	1986-09-30	Thiazolidinecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL87644A0 (en)	1989-02-28	Oxadiazolyl-azabicycloheptanes,their preparation and pharmaceutical compositions containing them
IL85969A0 (en)	1988-09-30	Ribofuranuronic acid derivatives and pharmaceutical compositions containing them
IL83049A (en)	1991-12-12	4-quinolinone-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
IL84808A (en)	1991-07-18	Furanuronic acid derivatives,their preparation and pharmaceutical compositions containing them
GB2201676B (en)	1991-01-02	Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it
IL81165A0 (en)	1987-08-31	Aminoglycoside nor-cholanic acid lactams,their preparation and pharmaceutical compositions containing them
IL88237A0 (en)	1989-06-30	Fluoromethoxyphenyl dihydropyridines,their preparation and pharmaceutical compositions containing them
IL86478A0 (en)	1988-11-15	Substituted vinylcephalosporins,their preparation and pharmaceutical compositions containing them
IL86926A0 (en)	1988-11-30	1h-pyrazole-1-alkanamides,their preparation and pharmaceutical compositions containing them
IL87130A0 (en)	1988-12-30	Hydrocinnamic acid derivatives,their manufacture and pharmaceutical compositions containing them
IL75913A (en)	1989-06-30	Phenyl-nonatetraenoic acid derivatives,their preparation and pharmaceutical compositions containing them
IL85612A0 (en)	1988-08-31	4-phenylpiperidine compounds,their preparation and pharmaceutical compositions containing them
IL75775A0 (en)	1985-11-29	Aminoeburnanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL88743A0 (en)	1989-07-31	Soluble recombinant fcepsilon-receptor,its preparation and pharmaceutical compositions containing it
IL85824A0 (en)	1988-09-30	Pyrrolealdehydes,their preparation and pharmaceutical compositions containing them
GB2206115B (en)	1991-04-03	8a-acylaminoergoline, its preparation and pharmaceutical compositions containing it
IL88673A0 (en)	1989-07-31	N-hydroxy-5-phenyl-2-furancarboxi-midamides,and pharmaceutical compositions containing them
IL84633A0 (en)	1988-04-29	1-aryloxy-3-amino-2-propanols,their preparation and pharmaceutical compositions containing them
IL75776A (en)	1989-07-31	Nitroapovincaminic acid derivatives,their preparation and pharmaceutical compositions containing them

GB2201676B - Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it - Google Patents

Info

Links

Classifications

Landscapes

Applications Claiming Priority (1)

Publications (3)

Family

ID=10612501

Family Applications (2)

Family Applications Before (1)

Country Status (28)

Cited By (1)

Families Citing this family (8)

Citations (1)

Patent Citations (1)

Cited By (1)

Also Published As

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Legal Events