GB2249172A - Multichannel pipette - Google Patents
Multichannel pipette Download PDFInfo
- Publication number
- GB2249172A GB2249172A GB9023405A GB9023405A GB2249172A GB 2249172 A GB2249172 A GB 2249172A GB 9023405 A GB9023405 A GB 9023405A GB 9023405 A GB9023405 A GB 9023405A GB 2249172 A GB2249172 A GB 2249172A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tips
- separable
- members
- tip
- strip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000004891 communication Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 description 6
- 238000012423 maintenance Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 241001504505 Troglodytes troglodytes Species 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000000881 depressing effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000005497 microtitration Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Abstract
The pipette comprises a casing with end cylindrical members (2) whose lower portions (3) have tapered external surfaces. The pipette includes separable tips (4) lifted in the lower portions (3) of the members (2). The external surface of the members (2) accommodates a strip (5) to remove the tips and which is moveable along the members (2). The lower surface of the strip (5) is adapted to remove the tips and has variable-height projections (7). each of which is disposed opposite each tip (4). <IMAGE>
Description
MULTI CHANNEL PIPETTE
The present invention relates to facilities for chemical and physical laboratories, more particularly, to multichannel pipettes.
The invention may find applications for dosing liquids in biological, chemical and biochemical research and in medicine.
There is widely known a pipette (cf. Flow laboratories, GB, Titerec Multi-channel Pipettes for Microtitra- tion, No. 77-859-00, 1977) comprising a vertical casing and cylindrical members secured to the lower surface of the casing, the lower portion of the cylindrical members having a tapered external surface. A separable tip is hermetically fitted over the tapered external surface of each cylindrical member. A strip designed for removing separable tips is installed on the external surface of the cylindrical members in a manner allowing its movement along said cylindrical members. The known pipette also comprises a strip motion drive made as a rod having its lower end secured to the strip, while its upper end accommodates a button.The strip motion drive rod is spring-loaded and fitted through a hole in a projection provided in the lower portion of the casing.
To remove the separable tips on completion of the dosing operation when the liquid has been drained from the separable tips, it is necessary to depress the button which compresses the sprint and sets in motion the strip through the rod during its downward movement. At the same time, the lower surface of the strip bears against all the tips, thus causing them to move from the tapered surface of the cylindrical members to a vessel for receiving used separable tips.
The button is released after the separable tips have been removed. Thus, the button moving upwards under the action of the opposing spring sets the strip to the initial position. So, the used separable tips are thrown off without being touched by the operator. However, in the known pipette all the separable tips are thrown off simultaneously and the operator has to apply considerable force to depress the button since each separable tip is hermetically fitted over the tapered external surface of the cylindrical member, the total number of said separable tips being up to twelve.
Furthermore great force applied to throw off the separable tips causes them to leave the tapered surface of the cylindrical members at a high speed whereby drops of the dosed-out liquids remaining in the separable tips will be splashed as said tips strike the bottom of the vessel for receiving used separable tips, a disadvantage causing difficulties in maintenance of the known pipette when corrosive or toxic liquids are dosed out.
According to the present invention there is provided a multi channel pipette comprising a plurality of pipette members, each having means for carrying a separable tip, tip removing means mounted for movement relative to the members for engaging and displacing the tips to remove the tips from said members, the tip removing means being arranged to engage and remove tips successively from respective members upon operation of said tip removing means.
Mbre samfically there is provided a multich m el pipette cornprising a casing, cylindrical members secured to cne lower end of the casing and having their internal cavity communicating with the internal catty of the casing, their lower portion having a tapered external surface, separable tips fitted hermetically in the lower portion of the cylindrical members, and a strip adapted for removing the separable tips and installed on the external surface of the cylindrical members in a manner allowing its movement along said cylindrical members, in which, according to tne invention, the locker surface of the strip adapted for removing the separable tips has variable eight prozections, each of which is disposed opposite each separable tip.
It is advantageous that, with a view to increasing further convenience in maintenance of the proposed multichannel pipette with the cylindrical members arranged in one row, the height of the projections of the strip adapted for removing the separable tips sriould chance linearly in the direction from the first to the last separable tip.
The present invention provides for smooth removal of used separable tips due to a novel structural embodiment of the strip adapted for removing the separable tips, a feature maKing more convenient maintenance of the multichannel pipette according to the invention.
The invention will now be described further with reference to a specific embodiment thereof, taken in conjunction with the accompanying drawings wherein: Figure 1 is a general front view (partial longi tudinal section) of a multichannel pipette according to the invention; and
Figure 2 shows on an enlarged scale the lower portion of the multichannel pipette (side view, longitudinal section) according to the invention
The proposed multichannel pipette comprises a casing 1 (Figure 1), its lower end mounting cylindrical members 2 wnose internal cavity is in communication with t.e internal cavity of the casing 1. A lower portion 3 (Figure 1, 2) of each cylinorical member has a tapered external surface. Separable tips 4 are fitted in the tapered lower portion 3 of the cylindrical members 2.
The multichannel pipette forming the subject of the present invention also comprises a strip 5 adapted for removing separable tips and installed on the external surface of the cylindrical members 2 in a manner allowing sliding movement thereof along the cylindrical members 2.
The strip 5 has holes 6 (Figure 2) accommodating the cylindrical members 2.
The lower surface of the strip 5 is provided with variable-beight projections 7. Each projection 7 is disposed opposite each separable tip 4. In the preferred embodiment of the invention with the cylindrical members 2 arranged in one row, tne height of the projections 7 of the strip 5 changes linearly in the direction from the first to tne last separable tip 4.
The multichannel pipette according to the invention further includes a strip motion drive comprising rods 8 (Figure 1) whose lower ends are secured to the strip 5, a rod 9 loaded vertically with a spring 10 and mounting on its upper end a button 11, and a sleeve 12, tne upper ends of the rods 8 being fixed in the lower portion of said sleeve, while the lower end of the rod 9 is fixed in its upper portion.
The rods 8 are fitted in holes 13 in a rectangular projection 14 provided in a lover portion 15 of the casing 1. The rod 9 encompassed by tr.e srin 10 is fitted in a hole 16 in an upper portion 17 of tne casing 1.
The multi channel pipette according to the invention functIons as follows.
On completion of the dosing operation, wren the liquid is fully drained from the separable tips 4 (Figure 1) there occurs removal of the separable tips 4. This is done by depressing the button 11 which moves downwards, thereby compressing the spring 10 and setting in motion via the rods 8, 9 the strip 5 adapted for removing the separable tips.
The highest projection 7 (Figure 2) of the strip 5 bears against the separable tip 4 disposed opposite the projection 7, thus causing the tip 4 to move from the tapered surface of the cylindrical members 2 to the vessel for receiving used separable tips (not snown in
Figure 1). Thereafter the strip 5 continues to move downwards bearing against the separable tips 4 with its second highest projections 7 whereby the separable tips 4 will be successively thrown off.
The operator releases the button 11 after the last separable tip 4 has been removed. The button 11 moves upwards unuer the action of the opposing spring 10, thus returning the strip 5 to the initial posi tlon.
While the separable tips 4 are successively thrown off, the strip 5 is in contact 'with one of the separable tips 4 and, in effect, a maximum force applied to the button 11 does not exceed the force required to throw off one separable tip 4. So, maintenance of t.le proposed multichannel pipette is made easier without introducing unwanted structural complexities.
The present invention permits enhancing efficiency of laboratorg work by decreasing fatiguability of operators engaged in repeating many times the procedures of removing used separable tips of multichannel pipettes, another advantage tnereof being easier maintenance of the aforesaid pipettes in dosing out corrosive and toxic liquids.
Claims (4)
1. A multichannel pipette comprising a plurality of pipette members, each having means for carrying a separable tip, tip removing means mounted for movement relative to the members for engaging and displacing the tips to remove the tips from said members, the tip removing means being arranged to engage and remove tips successively from respective members upon operation of said tip removing means.
2. A multichannel pipette comprising a casing; cylindrical members secured to a lower end of the casing, their internal cavity being in communication with the internal cavity of the casing, while their lower portion has a tapered external surface; separable tips fitted hermetically over the tapered external surfaces of the cylindrical members; and a strip adapted for removing the separable tips and installed on the external surface of the cylindrical members in a manner allowing its movement along the cylindrical members, the lower surface of the strip having variable-height projections, each of which is disposed opposite each separable tip.
3. A multichannel pipette as claimed in claim 2 wherein with the cylindrical members arranged in one row the height of the projections of the strip adapted for removing the separable tips linearly changes in the direction from the first to the last separable tip.
4. A multichannel pipette substantially as hereinabove described with reference to, and as shown in the accompanying drawings.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9023405A GB2249172A (en) | 1990-10-26 | 1990-10-26 | Multichannel pipette |
| FR9013467A FR2668390A1 (en) | 1990-10-26 | 1990-10-30 | Multichannel pipette |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9023405A GB2249172A (en) | 1990-10-26 | 1990-10-26 | Multichannel pipette |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB9023405D0 GB9023405D0 (en) | 1990-12-05 |
| GB2249172A true GB2249172A (en) | 1992-04-29 |
Family
ID=10684454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB9023405A Withdrawn GB2249172A (en) | 1990-10-26 | 1990-10-26 | Multichannel pipette |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR2668390A1 (en) |
| GB (1) | GB2249172A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000069562A1 (en) * | 1999-05-18 | 2000-11-23 | Socorex Isba S.A. | Pipette with tip ejector |
| WO2001012330A1 (en) * | 1999-08-17 | 2001-02-22 | The Technology Partnership Plc | Flexible pipette strip and method of its use |
| CN103163310A (en) * | 2013-03-15 | 2013-06-19 | 东南大学 | Multi-channel micro-volume sampling device |
| CN107619002A (en) * | 2016-08-22 | 2018-01-23 | 徐勤凤 | A kind of quantitative lifting device of extracting liq |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2115719A (en) * | 1982-02-16 | 1983-09-14 | Data Packaging Corp | Multi-channel pipetter |
| US4779467A (en) * | 1987-01-28 | 1988-10-25 | Rainin Instrument Co., Inc. | Liquid-end assembly for multichannel air-displacement pipette |
| US4824642A (en) * | 1986-10-21 | 1989-04-25 | Costar Corporation | Multi-channel pipetter |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2161398A (en) * | 1984-07-11 | 1986-01-15 | Scient Supplies M B | Pipette |
| US5061449A (en) * | 1989-07-25 | 1991-10-29 | Matrix Technologies, Corp. | Expandable multi-channel pipetter |
-
1990
- 1990-10-26 GB GB9023405A patent/GB2249172A/en not_active Withdrawn
- 1990-10-30 FR FR9013467A patent/FR2668390A1/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2115719A (en) * | 1982-02-16 | 1983-09-14 | Data Packaging Corp | Multi-channel pipetter |
| US4824642A (en) * | 1986-10-21 | 1989-04-25 | Costar Corporation | Multi-channel pipetter |
| US4779467A (en) * | 1987-01-28 | 1988-10-25 | Rainin Instrument Co., Inc. | Liquid-end assembly for multichannel air-displacement pipette |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000069562A1 (en) * | 1999-05-18 | 2000-11-23 | Socorex Isba S.A. | Pipette with tip ejector |
| EP1185368A1 (en) * | 1999-05-18 | 2002-03-13 | Socorex Isba S.A. | Pipette with tip ejector |
| US6833114B1 (en) | 1999-05-18 | 2004-12-21 | Socorex Isba S.A. | Pipette with tip ejector |
| WO2001012330A1 (en) * | 1999-08-17 | 2001-02-22 | The Technology Partnership Plc | Flexible pipette strip and method of its use |
| CN103163310A (en) * | 2013-03-15 | 2013-06-19 | 东南大学 | Multi-channel micro-volume sampling device |
| CN107619002A (en) * | 2016-08-22 | 2018-01-23 | 徐勤凤 | A kind of quantitative lifting device of extracting liq |
| CN107619002B (en) * | 2016-08-22 | 2019-07-26 | 汉高乐泰(宁夏)新材料有限公司 | A quantitative lifting device for extracting liquid |
Also Published As
| Publication number | Publication date |
|---|---|
| GB9023405D0 (en) | 1990-12-05 |
| FR2668390A1 (en) | 1992-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |