IT1302530B1 - PREPARATION PROCESS FOR GANGLIOSIDE GM3 AND ITS LYSODERIVATES TO START FROM GANGLIOSIDE GM1. - Google Patents

PREPARATION PROCESS FOR GANGLIOSIDE GM3 AND ITS LYSODERIVATES TO START FROM GANGLIOSIDE GM1.

Info

Publication number: IT1302530B1
Authority: IT; Italy
Prior art keywords: ganglioside; lysoderivates; preparation process; preparation
Prior art date: 1998-12-16

Application number

Other languages

Italian (it)

Inventor

Gunter Kirschner

Sandro Sonnino

Original Assignee

Fidia Spa In Amministrazione S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-16

Filing date

1998-12-16

Publication date

2000-09-05

1998-12-16 Application filed by Fidia Spa In Amministrazione S filed Critical Fidia Spa In Amministrazione S

1998-12-16 Priority to IT000293 priority Critical patent/IT1302530B1/en

1999-12-15 Priority to PCT/EP1999/009958 priority patent/WO2000035932A1/en

1999-12-15 Priority to EP99963541A priority patent/EP1140961A1/en

1999-12-15 Priority to AU19798/00A priority patent/AU1979800A/en

1999-12-15 Priority to CA002355106A priority patent/CA2355106A1/en

2000-06-16 Publication of ITPD980293A1 publication Critical patent/ITPD980293A1/en

2000-09-05 Application granted granted Critical

2000-09-05 Publication of IT1302530B1 publication Critical patent/IT1302530B1/en

Links

QPJBWNIQKHGLAU-IQZHVAEDSA-N ganglioside GM1 Chemical compound O[C@@H]1[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)[C@@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](CO)O1 QPJBWNIQKHGLAU-IQZHVAEDSA-N 0.000 title 1
PFJKOHUKELZMLE-VEUXDRLPSA-N ganglioside GM3 Chemical compound O[C@@H]1[C@@H](O)[C@H](OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O)[C@@H](CO)O1 PFJKOHUKELZMLE-VEUXDRLPSA-N 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Crystallography & Structural Chemistry (AREA)
Saccharide Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT000293 1998-12-16 1998-12-16 PREPARATION PROCESS FOR GANGLIOSIDE GM3 AND ITS LYSODERIVATES TO START FROM GANGLIOSIDE GM1. IT1302530B1 (en)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
IT000293 IT1302530B1 (en)	1998-12-16	1998-12-16	PREPARATION PROCESS FOR GANGLIOSIDE GM3 AND ITS LYSODERIVATES TO START FROM GANGLIOSIDE GM1.
PCT/EP1999/009958 WO2000035932A1 (en)	1998-12-16	1999-12-15	Process for the preparation of ganglioside gm3 by acid hydrolysis of ganglioside inner esters and its use in the pharmaceutical field
EP99963541A EP1140961A1 (en)	1998-12-16	1999-12-15	Process for the preparation of ganglioside gm3 by acid hydrolysis of ganglioside inner esters and its use in the pharmaceutical field
AU19798/00A AU1979800A (en)	1998-12-16	1999-12-15	Process for the preparation of ganglioside gm3 by acid hydrolysis of gangliosideinner esters and its use in the pharmaceutical field
CA002355106A CA2355106A1 (en)	1998-12-16	1999-12-15	Process for the preparation of ganglioside gm3 by acid hydrolysis of ganglioside inner esters and its use in the pharmaceutical field

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT000293 IT1302530B1 (en)	1998-12-16	1998-12-16	PREPARATION PROCESS FOR GANGLIOSIDE GM3 AND ITS LYSODERIVATES TO START FROM GANGLIOSIDE GM1.

Publications (2)

Publication Number	Publication Date
ITPD980293A1 ITPD980293A1 (en)	2000-06-16
IT1302530B1 true IT1302530B1 (en)	2000-09-05

Family

ID=11392394

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT000293 IT1302530B1 (en)	1998-12-16	1998-12-16	PREPARATION PROCESS FOR GANGLIOSIDE GM3 AND ITS LYSODERIVATES TO START FROM GANGLIOSIDE GM1.

Country Status (5)

Country	Link
EP (1)	EP1140961A1 (en)
AU (1)	AU1979800A (en)
CA (1)	CA2355106A1 (en)
IT (1)	IT1302530B1 (en)
WO (1)	WO2000035932A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT201800007093A1 (en) *	2018-07-11	2020-01-11		Oligosaccharides for use in the treatment of Parkinson's disease
CN110507663A (en) *	2019-08-07	2019-11-29	南昌大学	Application of ganglioside GM3 in the preparation of drugs for the treatment of atherosclerosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4476119A (en) *	1981-08-04	1984-10-09	Fidia S.P.A.	Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
IT1199116B (en) *	1984-07-03	1988-12-30	Fidia Farmaceutici	GANGLIOSIDE DERIVATIVES
JP3845121B2 (en) *	1994-09-30	2006-11-15	雪印乳業株式会社	Production method of ganglioside
US5977329A (en) *	1996-02-16	1999-11-02	Ludwig Institute For Cancer Research	Methods of synthesizing GM3

1998
- 1998-12-16 IT IT000293 patent/IT1302530B1/en active IP Right Grant
1999
- 1999-12-15 CA CA002355106A patent/CA2355106A1/en not_active Abandoned
- 1999-12-15 WO PCT/EP1999/009958 patent/WO2000035932A1/en not_active Ceased
- 1999-12-15 EP EP99963541A patent/EP1140961A1/en not_active Withdrawn
- 1999-12-15 AU AU19798/00A patent/AU1979800A/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2000035932A1 (en)	2000-06-22
EP1140961A1 (en)	2001-10-10
ITPD980293A1 (en)	2000-06-16
CA2355106A1 (en)	2000-06-22
AU1979800A (en)	2000-07-03

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Legal Events

Date	Code	Title	Description
2000-09-05	0001	Granted