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IL266388B2 - Respiratory early warning scoring systems and methods - Google Patents
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IL266388B2 - Respiratory early warning scoring systems and methods - Google Patents

Respiratory early warning scoring systems and methods

Info

Publication number
IL266388B2
IL266388B2 IL266388A IL26638819A IL266388B2 IL 266388 B2 IL266388 B2 IL 266388B2 IL 266388 A IL266388 A IL 266388A IL 26638819 A IL26638819 A IL 26638819A IL 266388 B2 IL266388 B2 IL 266388B2
Authority
IL
Israel
Prior art keywords
patient
early warning
bioelectrical impedance
ews
scoring system
Prior art date
Application number
IL266388A
Other languages
Hebrew (he)
Other versions
IL266388A (en
IL266388B1 (en
Inventor
E Freemanjenny
Jordan Brayanov
Original Assignee
Respiratory Motion Inc
E Freemanjenny
Jordan Brayanov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respiratory Motion Inc, E Freemanjenny, Jordan Brayanov filed Critical Respiratory Motion Inc
Publication of IL266388A publication Critical patent/IL266388A/en
Publication of IL266388B1 publication Critical patent/IL266388B1/en
Publication of IL266388B2 publication Critical patent/IL266388B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022Monitoring a patient using a global network, e.g. telephone networks, internet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0024Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system for multiple sensor units attached to the patient, e.g. using a body or personal area network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7275Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Primary Health Care (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)

Description

266388/ are sheared and can be expectorated or removed with suction. After the exhale, the system pauses and maintains a resting positive pressure flow to the patient. A facemask or mouthpiece can be used on endotracheal and tracheostomy (i.e. for patients with an appropriate adapter).
Preferably, the cough assist device automatically adjusts characteristic therapy levels (frequency, intensity, length of therapy, inhalation pressure, exhalation pressure) based on the levels of tidal volume, minute ventilation, and respiratory rate during therapy. In addition, the general within session and the session-to-session lung performance can be tracked to demonstrate effectiveness of the therapy (before, during, and after and across many sessions). Graphs could be provided to document breathing characteristics of the patient and to demonstrate improvement to the patient over time.
In addition, the characteristic shape of the bioimpedance expansion curve is an indicator of the success of each individual cough. Appropriate curves for maximizing exudate removal can be identified and the adjustment levels of the Cough assist System (frequency, intensity, length of therapy, inhalation pressure, and exhalation pressure) can be adjusted to get the desired cough expulsion curve. Characteristics of the cough assist can be adjusted to ensure the optimal results are provided for each individual patient.
Other embodiments and technical advantages of the invention are set forth below and may be apparent from the drawings and the description of the invention which follow, or may be learned from the practice of the invention.
Other embodiments and uses of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. The term comprising, where ever used, is intended to include the terms consisting and consisting essentially of. Furthermore, the terms comprising, including, and containing are not intended to be limiting. It is intended that the specification and examples be considered exemplary only with the true scope and spirit of the invention indicated by the following claims .

Claims (26)

1./ Claims 1. An early warning scoring system, the system comprising: a computing device having acquisition circuitry; a plurality of sensors for acquiring bioelectrical impedance signals from a patient, wherein the sensors are functionally connected to the acquisition circuitry and are adapted to be placed in one or more tetrapolar configurations on the chest of the patient; and at least one alarm adapted to output an alert upon an early warning score (EWS) exceeding a predetermined level; wherein the computing device: receives the bioelectrical impedance signals from the sensors; determines a calibration coefficient based on the bioelectrical impedance signals and demographic information of the patient; calibrates the bioelectrical impedance signals; analyzes the calibrated bioelectrical impedance signals; based on the analyzed signals, calculates the early warning score; and compares the early warning score to predetermined limits and, if the score is outside the limits, triggers the at least one alarm or actuates or modifies a treatment or medical intervention.
2. The early warning scoring system of claim 1, wherein the computing device provides an assessment of minute ventilation, tidal volume, and/or respiratory rate of the patient based on the bioelectrical impedance signal.
3. The early warning scoring system of claim 2, wherein the EWS calculation includes at least one of the minute ventilation, tidal volume, and/or respiratory rate of the patient.
4. The early warning scoring system of claim 2, wherein the EWS calculation includes minute ventilation and does not include respiratory rate.
5. The early warning scoring system of claim 1, wherein the EWS is indicative of at least one of respiratory failure, sepsis, cardiac failure, congestive heart failure, renal failure, 266388/ over-hydration, pulmonary edema, hyper metabolic state, overexertion, traumatic brain injury, pulmonary embolus, opioid induced respiratory depression, over sedation.
6. The early warning scoring system of claim 1, wherein the sensors obtain patient data relating to at least one of minute ventilation, tidal volume, respiratory rate, oxygen saturation, temperature, blood pressure, pulse or heart rate, blood oxygen levels, and brain activity.
7. The early warning scoring of claim 1, wherein the at least one alarm is at least one of audible or visual.
8. The early warning scoring system of claim 1, wherein at least two sensors are placed on the torso of the patient and a physiological bioelectrical impedance signal is measured transthoracically.
9. The early warning scoring system of claim 1, wherein the computing device further: obtains patient data comprising alertness, voice, pain, and unresponsiveness (AVPU) of the patient; and the EWS calculation includes the patient’s AVPU data.
10. The early warning scoring system of claim 1, wherein the system is non-invasive.
11. The early warning scoring system of claim 1, wherein the EWS calculation includes the patient’s disease state and/or circumstance.
12. The early warning scoring system of claim 1, wherein the EWS calculation includes the patient’s age, demographics, condition, and/or data from the patient’s electronic health records.
13. The early warning scoring system of claim 1, wherein the system is a triage system, a mobilization protocol system, a training protocol system, or an activity and/or nutrition regimen system. 266388/
14. A method of calculating an early warning score (EWS), the method comprising the steps of: coupling a plurality of sensors for acquiring bioelectrical impedance signals to a patient in one or more tetrapolar configurations on the chest of the patient; receiving the bioelectrical impedance signals from the sensors; determining a calibration coefficient based on the bioelectrical impedance signals and demographic information of the patient; calibrating the bioelectrical impedance signals; analyzing the calibrated bioelectrical impedance signals; based on the analyzed signals, calculating the EWS; and comparing the early warning score to predetermined limits and, if the score is outside the limits, triggering at least one alarm or actuating or modifying a treatment or medical intervention.
15. The method of claim 14, wherein the method further provides an assessment of minute ventilation, tidal volume, and/or respiratory rate of the patient based on the bioelectrical impedance signal.
16. The method of claim 15, wherein the EWS calculation includes at least one of the minute ventilation, tidal volume, and/or respiratory rate of the patient.
17. The method of claim 15, wherein the EWS calculation includes minute ventilation and does not include respiratory rate.
18. The method of claim 14, wherein the EWS is indicative of at least one of respiratory failure, sepsis, cardiac failure, congestive heart failure, renal failure, over-hydration, pulmonary edema, hyper metabolic state, overexertion, traumatic brain injury, pulmonary embolus, opioid induced respiratory depression, over sedation.
19. The method of claim 14, wherein the sensors obtain patient data relating to at least one of minute ventilation, tidal volume, respiratory rate, oxygen saturation, temperature, blood pressure, pulse or heart rate, blood oxygen levels, and brain activity. 266388/
20. The method of claim 14, wherein the at least one alarm is at least one of audible or visual.
21. The method of claim 14, wherein at least two sensors are placed on the torso of the patient and a physiological bioelectrical impedance signal is measured transthorasically.
22. The method of claim 14, further comprising: obtaining patient data comprising alertness, voice, pain, and unresponsiveness (AVPU) of the patient, wherein the EWS calculation includes the patient’s AVPU data.
23. The method of claim 14, wherein the method is non-invasive.
24. The method of claim 14, wherein the EWS calculation includes the patient’s disease state and/or circumstance.
25. The method of claim 14, wherein the EWS calculation includes the patient’s age, demographics, condition, and/or data from the patient’s electronic health records.
26. The method of claim 14, wherein the method is a triage method, a mobilization protocol method, a training protocol method, or an activity and/or nutrition regimen method. Webb+Co. Patent Attorneys
IL266388A 2016-11-02 2019-05-01 Respiratory early warning scoring systems and methods IL266388B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662416416P 2016-11-02 2016-11-02
PCT/US2017/059754 WO2018085563A1 (en) 2016-11-02 2017-11-02 Respiratory early warning scoring systems and methods

Publications (3)

Publication Number Publication Date
IL266388A IL266388A (en) 2019-06-30
IL266388B1 IL266388B1 (en) 2023-04-01
IL266388B2 true IL266388B2 (en) 2023-08-01

Family

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Family Applications (1)

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IL266388A IL266388B2 (en) 2016-11-02 2019-05-01 Respiratory early warning scoring systems and methods

Country Status (10)

Country Link
EP (1) EP3528694A4 (en)
JP (1) JP2020503085A (en)
KR (1) KR20190071808A (en)
CN (1) CN109996488B (en)
AU (1) AU2017354162A1 (en)
BR (1) BR112019010552A2 (en)
CA (1) CA3042686A1 (en)
IL (1) IL266388B2 (en)
MX (1) MX2019005195A (en)
WO (1) WO2018085563A1 (en)

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Also Published As

Publication number Publication date
CN109996488B (en) 2022-11-01
EP3528694A4 (en) 2020-10-14
AU2017354162A1 (en) 2019-06-06
EP3528694A1 (en) 2019-08-28
BR112019010552A2 (en) 2019-09-17
CN109996488A (en) 2019-07-09
MX2019005195A (en) 2019-09-19
KR20190071808A (en) 2019-06-24
IL266388A (en) 2019-06-30
IL266388B1 (en) 2023-04-01
WO2018085563A1 (en) 2018-05-11
JP2020503085A (en) 2020-01-30
CA3042686A1 (en) 2018-05-11

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