JP2696458B2 - Emollient cosmetic - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a soft skin emollient which is weakly acidic at the pH of the skin, is excellent in moisturizing properties and softness of the stratum corneum, and continuously and safely protects the skin from drying and roughness.

[0002]

2. Description of the Related Art In addition to weather conditions such as low-temperature conditions and low-humidity conditions, skin becomes dry or rough due to excessive use of detergents and solvents. Such skin changes are due to NMF (Natural Moisturizer; Natural) in its outermost layer, the stratum corneum.
It is thought that this occurs because a water-absorbing water-soluble component called a moisturizing factor is lost, moisture in the stratum corneum decreases, and the stratum corneum loses its flexibility. Therefore, conventional moisturizing cosmetics have been compounded with various humectants for the purpose of imparting a large amount of water to the stratum corneum and maintaining it for a long time.

Conventionally, as moisturizers incorporated in emollient cosmetics, organic acids and amino acids, which are one of natural moisturizing components, are exemplified. Among the organic acids, α-oxy acids have been proposed to be blended in cosmetics because they have an excellent softening effect on the stratum corneum (Japanese Patent Publication No. 55-19291). However, α-oxyacids have many drawbacks such that their effects are exhibited only in a low pH range (pH 2 to 4) that inhibits normal skin physiology. To compensate for this drawback, some cosmetics have been added to a neutral pH range by adding a strong alkali such as sodium hydroxide or potassium hydroxide or an amine such as triethanolamine. However, this strong alkali has a drawback that when it is mixed in a large amount, the stability is deteriorated and it is difficult to adjust the pH to the skin pH range, so that the quality of the cosmetic obtained is not constant. On the other hand, amines may cause an allergic reaction,
It is not preferable from the viewpoint of safety. From such a viewpoint, a combination of an α-oxy acid and a basic amino acid has also been studied (Japanese Patent Publication No. 3-30566), but its skin softening effect was not sufficiently satisfactory.

On the other hand, amino acid humectants include degradation products of proteins such as yoquinin (Japanese Patent Publication No. 58-8007) and various peptides (Japanese Patent Publication Nos. 48-23944 and 62-99315). Fairness 2-17820
No. 7) is used. However, the skin softening effects of these amino acids and peptides have not been sufficiently satisfactory.

[0005]

SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide a cosmetic having a sustained and excellent softening effect on the stratum corneum without impairing normal skin physiology.

[0006]

Under these circumstances, the present inventors have made intensive studies to solve the above-mentioned problems, and as a result, have found that a specific amount of a basic amino acid, a dicarboxylic acid having no hydroxyl group and a phosphate are blended. With this, it is possible to obtain a highly acidic cosmetic that is weakly acidic, which is the normal pH of the skin, has excellent moisturizing properties and softness of the stratum corneum, has a long-lasting action, and is highly safe compared to conventional cosmetics. As a result, the present invention has been completed.

That is, the present invention provides a dicarboxylic acid having no hydroxyl group or a salt thereof and a basic amino acid or a salt thereof in a total amount of 0.01 to 30% by weight, and a phosphoric acid or a salt thereof in a concentration of 0.1 to 15%. The present invention provides an emollient cosmetic having a pH of 4 to 6 and containing a weight percent.

The dicarboxylic acid having no hydroxyl group used in the present invention includes, for example, succinic acid, glutaric acid, adipic acid and the like. Examples of the salts of these dicarboxylic acids include alkali metal salts such as sodium salts and potassium salts, and alkanolamine salts such as triethanolamine salts.

[0009] Examples of the basic amino acid include lysine, arginine, histidine, ornithine, canavanine and the like. Salts of these basic amino acids include mineral salts such as hydrochlorides.

These hydroxyl-free dicarboxylic acids or salts thereof and basic amino acids or salts thereof can be used singly or in combination of two or more, respectively. To 30% by weight (hereinafter simply referred to as%), more preferably 0.01 to
20% is blended. If the total amount is less than 0.01%, the skin softening effect is not sufficient, and if it exceeds 30%, salt is precipitated in the system, which is not preferable. The mixing ratio of the dicarboxylic acid and the basic amino acid is 1: 1:
It is preferably from 0.1 to 0.1: 1, particularly preferably from 1: 0.3 to 0.3: 1.

The phosphoric acid or a salt thereof used in the present invention includes phosphoric acid, monosodium phosphate, disodium phosphate and the like. These can be used alone or in combination of two or more kinds.
15% is blended.

The emollient cosmetic of the present invention is produced by blending the above-mentioned components and adjusting the pH to 4-6.
Outside this pH range, the normal physiological function of the skin may be impaired, which is not preferred.

The cosmetic of the present invention may contain, if necessary, various optional components commonly used in cosmetics, quasi-drugs, pharmaceuticals, etc. as long as the effects of the present invention are not impaired. Such optional components include, for example, purified water,
Ethanol, oily ingredients, other humectants, thickeners, preservatives,
Surfactants, antioxidants, chelating agents, ultraviolet absorbers,
Powders, pigments, medicinal ingredients, fragrances and the like, specifically, as the oily component, liquid paraffin, petrolatum, paraffin wax, squalane, beeswax, carnauba wax, olive oil, lanolin, higher alcohols, fatty acids,
Synthetic ester oils of higher alcohols and fatty acids, silicone oils, and the like. Other humectants include sorbitol, xylitol, glycerin, maltitol, propylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, and pyrrolidone carboxylic acid. Sodium acid, polyoxypropylene fatty acid ester, polyethylene glycol and the like, as a thickener carboxyvinyl polymer, carboxymethylcellulose, polyvinyl alcohol, carrageenan, water-soluble polymers such as gelatin,
Examples include electrolytes such as sodium chloride and potassium chloride, and as preservatives, methyl paraben, ethyl paraben,
Propylparaben, butylparaben, sodium benzoate and the like.Examples of the surfactant include polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, and polyoxyethylene. Non-ionic surfactants such as glycerin fatty acid ester, polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitol fatty acid ester, and the like, and as powders, talc, sericite, mica, kaolin, silica, bentonite, vermiculite, zinc flower, Mica, titanium mica, titanium oxide, magnesium oxide, zirconium oxide, barium sulfate, red iron oxide, iron oxide, ultramarine and the like.

The dosage form of the emollient cosmetic of the present invention is not particularly limited, and examples thereof include lotions, emulsions, creams, packs,
Various solubilized or emulsified dosage forms such as foundations can be used.

[0015]

EFFECTS OF THE INVENTION The emollient cosmetic composition of the present invention has a sustained and excellent softening effect on the stratum corneum and is safe without impairing the physiological function of normal skin. It can prevent or improve skin dryness and roughness due to excessive use of water, detergents and solvents.

[0016]

EXAMPLES The present invention will be further described with reference to examples, but the present invention is not limited to these examples.

Example 1 A lotion having the composition shown in Table 1 was prepared, and its softening effect on the stratum corneum was examined. (1) Manufacturing method of lotion Arginine and carboxylic acids are dissolved in water, phosphates are added thereto, and water is further added. (2) Method for examining softening effect A 30 mm x 5 mm stratum corneum piece was immersed in lotion for 3 hours, dried and allowed to stand in a constant humidity, and then tan δ was measured using a dynamic viscoelastic device (manufactured by Rheology). Measure. The softening effect was determined by measuring the tan δ of the stratum corneum treated with a mixture of acetone: ether = 1: 1 determined as a blank for 30 minutes and with water for 30 minutes.
(A), tan δ of stratum corneum treated with test lotion
The ratio of (B) was represented by tan δ rate (B / A). (3) Results The obtained results are shown in Table 1. In the table, tanδ rate
The larger the value, the higher the flexibility of the stratum corneum. The results show that the lotion of the present invention is more excellent in skin softening effect than the combination of a basic amino acid and an oxycarboxylic acid or the combination of a basic amino acid and a monocarboxylic acid.

[0018]

[Table 1]

Embodiment 2

[0020]

Example 2 Comparative Example 3 1) Lysine hydrochloride 0.40 (%)-2) Histidine 0.40-3) Arginine 0.40-4) Succinic acid 0.68-5) Disodium phosphate 0 0.86 (%) 6) Glycerin 6.00 6.00 7) Dipropylene glycol 3.00 3.00 8) Polyethylene glycol (1500) 3.00 3.00 9) Polyoxyethylene isocetyl ether ( 20EO) 0.30 0.30 10) Ethyl alcohol 10.00 10.00 11) Fragrance trace trace 12) Preservative trace trace trace 13) Purified water Balance Balance

(Production method) 1) to 5) are added to purified water,
Dissolve at room temperature (water). To 10), 6), 7) 8), 9), 11) and 12) which were dissolved by heating are added, and dissolved at room temperature (alcohol part). Add alcohol part to water part,
Obtain a soft lotion. The above lotion was subjected to a sensory test by a specialized panelist, and as a result, the soft lotion of Example 2 was
Compared to the lotion of Comparative Example 3, the skin had an excellent moisturizing effect and a softening effect on the stratum corneum.

Embodiment 3

[0023]

Table 3 Example 3 Comparative Example 4 1) Vaseline 8.0 (%) 8.0 (%) 2) Lanolin 2.0 2.0 3) Squalene 20.0 20.0 4) Cetanol 5.0 5 0.0 5) Glycerin monostearate 2.0 2.0 6) Polyoxyethylene sorbitan monolaurate (20EO) 2.0 2.0 7) Ethyl paraben 0.2 0.2 8) Lysine hydrochloride 0.40-9 4.) Histidine 0.40-10) Arginine 0.40-11) Succinic acid 0.68-12) Disodium phosphate 0.86-13) Glycerin 5.0 5.0 14) 1,3-butylene glycol 0 5.0 15) Fragrance trace amount trace amount 16) Purified water balance balance

(Manufacturing method) 1) to 7) and 15) are dissolved by heating and kept at 80 ° C. (oil phase). 8) to 14) are dissolved in purified water, and the oil phase is added with stirring. After the homomixer treatment, the mixture was quenched to obtain a cream. As a result of a sensory test performed on the cream by a specialized panelist, the cream of the example showed an excellent moisturizing effect and a softening effect on the stratum corneum as compared with the cream of Comparative Example 4.

 ──────────────────────────────────────────────────続 き Continuation of front page (72) Inventor Seiji Yamazaki 252-7 Minami Hanajima Nakamachi, Matsudo-shi, Chiba No. 8 Izumi Mansion 405 (56) References JP-A-56-125313 (JP, A) JP-A-52 −102437 (JP, A)

Claims (1)

(57) [Claims] 1. A total of 0.01 to 3 of a dicarboxylic acid having no hydroxyl group or a salt thereof and a basic amino acid or a salt thereof.
0% by weight, and 0.1 to 15% by weight of phosphoric acid or a salt thereof
An emollient cosmetic having a pH of 4-6.