JP2775082B2 - Sample weighing method using automatic analyzer - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention uses an automatic analyzer .
The present invention relates to a method for weighing a sample . More specifically, an automatic analyzer that automated a series of continuous and parallel processes related to analysis by controlling with a computer was used.
The present invention relates to a method for weighing a sample .

[0002]

2. Description of the Related Art In the field of chemical analysis and the like, there is a strong demand for automating operations related to analysis, and many automatic analyzers have been proposed for various analyses. Representative examples of these automatic analyzers that automatically analyze a plurality of samples unattended include an automatic titrator, an automatic spectrometer, and other multifunctional automatic analyzers. Automatic titrators that are currently in practical use include a method of detecting and controlling the volume when collecting a sample and a method of detecting and controlling the weight.

[0003] In the former, by simply placing a beaker or a test tube containing a sample on a turntable of a sample changer, the sample can be automatically measured by volume detection, pretreatment such as drug injection and dilution, and titration can be performed automatically. In addition, devices that automate electrode cleaning and drainage are commercially available. However, higher requirements such as collection of a sealed sample, weighing, heating reaction, cooling, and the like are not performed. Also, contamination by the previous sample can be problematic.

[0004] In the latter, a human collects and weighs a sample using a system combining a balance, a titrator and a sample changer (the weighed value is taken into the titrator online), and the sample is placed on a turntable of the sample changer. When a beaker containing the beaker is placed, an apparatus is commercially available that performs from sample addition to titration through drainage treatment. However, a large space is required (usually a 200 ml beaker is used), the number of samples that can be set at one time is small (usually 12), weighing operation must be performed by humans, heating reaction and cooling cannot be performed. There is a problem.

On the other hand, in the automatic analysis system having more functions including preprocessing, there are many reports of a system in which a robot is arranged at the center. The use of a robot requires less study for automation, but on the other hand, it requires a large space and has problems such as the inability to move the system, a slow processing speed, and a high cost.

[0006]

As described above, the automatic analyzers currently on the market still have problems to be improved. One of the reasons, in these devices, which utilizes the rotation of the turntable as a method for transporting the sample container, simplify the apparatus, it has become a mainstream for reasons such as lower cost (JP 60-87
52 JP, Sho 59-87350 Patent Publication), and that the movement path of the sample container is limited on the outer periphery of a single turntable. In other words, since the size of the apparatus is limited, it is not possible to increase the number of individual operations when the sample container is enlarged, and conversely, when the sample container is reduced and the number of operations is increased, the individual When trying to increase the number of sample containers, the number of operations, the sample volume, and the like, such as the inability of the apparatus to be arranged around, various problems occur.
There are also attempts to solve this problem without using a turntable, but in many cases, other problems arise, as in the case of using the robot described above. The present invention provides a method of weighing a sample using a turntable type automatic analyzer that automatically analyzes a plurality of samples by an unmanned person in order to solve the above-mentioned problems. An object of the present invention is to provide a method for weighing a sample using an automatic analyzer that is compact, has a high processing speed , and can perform continuous processing and parallel processing while making the best use of the features.

[0007]

Means for Solving the Problems The present inventors have made intensive studies to solve the above-mentioned problems, and as a result, have completed the present invention. That is, the present invention provides an automatic analyzer for automatically analyzing a plurality sample while moving the measuring container, table arranged measuring container to be used for movement of the measuring container is a plurality of stages stacked disposed at a predetermined distance An elevator unit mounted so that a handling arm for grasping the measurement container to transfer the measurement container between the tables is moved in the vertical direction, and each device provided to the driving means and the analysis means is provided with an elevator. a weighing method is connected coupled to a control and Konpyuta performing arithmetic that is configured as capable of performing automatically continuous processing and parallel processing of multiple samples using automated analyzers sample, said plurality of stages stacked
Weighing turn arranged on the upper stage of the arranged table
The tip of the sampling arm located around the table
Dispense the sampling dispenser into the disposer insertion nozzle provided at the end.
Attach the tip and attach the tip of the disposable tip to the sample volume.
Insert the sample, aspirate the sample, and remove the sample in the disposable tip.
The sample is discharged into the measuring container on the electronic balance, weighed and
The density was determined, and the second suction amount was determined from the density.
Aspirate the sample into the disposable chip again, then measure
Weigh out the amount of sample discharged into the container and collected in the measuring container
Weighing of samples using an automatic analyzer characterized by performing
About the method.

[0008] The automatic analyzer of the present invention automatically analyzes a plurality of samples while moving the measurement container on the table. As a means for moving the measurement container, a belt conveyor system, a robot system, and an analyzer are frequently used. There is a turntable method and the like. The number of tables provided is not particularly limited as long as it is two or more, and can be appropriately set in consideration of the height of the apparatus, the size of the measurement container, and the like. Hereinafter, a description will be given by taking a turntable method having two stages, for example, as an example. However, other methods are the same as the turntable method except that the analysis means and the like are not installed in a circular shape. In the present invention, the upper turntable includes, for example, a unit that supplies a sample to a measurement container held on the outer periphery, a unit that weighs the supply amount of the sample, and a rotator that supplies the measurement container that stores the weighed sample. And a weighing unit comprising means for supplying a funnel to the measuring container. Specifically, for example, the holding parts of the measurement container are arranged on the outer periphery of the turntable, and as the place for holding the sample container, for example, the holding parts of the sample container may be arranged concentrically on its inner periphery. . The turntable is rotated by control of a computer or the like to move each container to a predetermined position. At this time, various devices such as a sample container opening / closing device, a sample collecting device, a sample discharging device, an automatic rotator feeding device, an automatic funnel feeding device, a weighing device, and the like are provided in a portion close to the turntable, and these are provided by a computer or the like. , A series of operations and processes such as sample collection, weighing, sample discharge, rotor automatic supply, funnel automatic supply, and the like can be automated and efficiently performed.

In the lower turntable, for example, a required amount of a reagent and / or a solvent is added to a measuring container equipped with a funnel for accommodating the sample transferred from the weighing unit, and a reaction, a cooling, and the like are performed. Means for removing the funnel from the measurement container after the treatment, means for titrating the reaction solution in the measurement container from which the funnel has been removed, and means for draining the reaction solution in the measurement container after completion of the titration. A reaction titrator is provided. Specifically, similarly to the upper stage, the holding portions of the measurement containers are arranged on the outer periphery of the turntable.
The turntable is rotated by control of a computer or the like to move each container to a predetermined position. At this time, various devices such as a reagent adding device, a reaction tank, a cooling device, a funnel washing-removing device,
A series of operations such as reagent addition, reaction, cooling, funnel washing-removal, titration, drainage, etc. are automated and efficiently performed by controlling these with a computer by providing a titrator, a drainage device, etc. be able to.

[0010] At the bottom of the apparatus below the lower turntable, for example, a storage section is provided. Specifically, it is a storage section for storing the measurement container and the like after the drainage transferred from the reaction titration section. When the above series of operations and processes are completed, the measurement container is transported and stored in the container storage tray of the storage unit by the elevator unit. In addition, tanks for reagents and the like may be provided in the storage section. This saves space and is effective in reducing the size of the apparatus.

[0011] As described above, the turntables are usually stacked and arranged at required intervals so that the weighing unit is at the top, the reaction titration unit is at the bottom, and the storage unit is at the bottom. Is not limited to the embodiment of
Furthermore, an automatic analyzer can be configured by laminating a large number. In addition, each operation or process to be used for analysis or the like is not limited to the above, and the order is not particularly limited.

In the automatic analyzer according to the present invention, the transfer of the measuring container between the units is performed by an elevator unit connecting the units. That is, the automatic analyzer of the present invention has an elevator section provided between these turntables, and by controlling the computer, can carry and transfer the measurement container held on the turntable. Each operation from to the bottom through the lower stage can be continued. Specific examples of such an elevator unit include, but are not limited to, a handling arm that grips a measuring container and a moving unit that can move the same vertically and horizontally. Not something. In this way, by successively performing the operations from the upper stage to the lower stage through to the storage of the container at the bottom, it is possible to further utilize the features of the turntable system and the like that enable continuous and parallel processing. In addition, all operations and processes can be automated, and control by a computer becomes more effective.

In the automatic analyzer according to the present invention, the apparatus used for each of the above means is connected to and connected to a computer for controlling and computing each other, so that it can automatically and continuously process a plurality of samples. I have.
As described above, the automatic analyzer of the present invention can be controlled by a computer or the like. However, the computer or the like may be provided outside the automatic analyzer and controlled online, or may be provided inside. When installing inside the device,
It is preferable to use a miniaturized device such as a microcomputer for saving space. Further, a dedicated sequence controller may be used for controlling the driving means and the like, and in this case, the driving means and the like may be controlled by a computer via the sequence controller. At this time, the system of the program for determining a series of operation procedures and the like may be either a rewritable system or a non-rewritable system.

When a computer is provided outside the automatic analyzer, it is connected to a dedicated or commercially available computer or the like via a dedicated interface. At this time, an input unit such as a keyboard, a display unit such as a display, an output unit such as a printer unit, and the like are also connected to the computer, and are subjected to a series of operations and processes. The computer to be used is not particularly limited as long as a series of processes and operations can be automatically performed by controlling operations and processes, performing calculations on data, and the like. When the computer is provided inside the automatic analyzer, for example, some or all of an input unit such as a keyboard, a display unit such as a display, and an output unit such as a printer unit may be provided integrally with the automatic analyzer. In this case, these functions and the like are the same as those provided externally.

[0015]

The automatic analyzer according to the present invention comprises a table on which a plurality of measurement containers stacked one above the other are installed. By arranging each table vertically and arranging various devices close to each other in this manner, the floor area occupied by the devices can be reduced and the entire device can be made compact. Another advantage is that many operations can be performed while the floor area occupied by the apparatus is kept small by stacking tables in multiple stages. In the case of the turntable method, all of the measurement containers and the like held by one operation of rotating the turntable can be simultaneously moved to the respective processing positions.
Individual operations and processes can be performed continuously and in parallel.

[0016]

EXAMPLES The present invention will now be described specifically with reference to examples, but the present invention is not limited to these examples. Embodiment 1 FIGS. 1 to 5 show an example of the automatic analyzer according to the present invention in the case where a turntable system is adopted as a means for moving a measuring container and a control computer is provided outside the automatic analyzer. 1 shows the system configuration, and the others show the whole or a part of the main body of the automatic analyzer.

The system configuration shown in FIG.
3, a computer unit including the display 102, the printer 104, and the computer main unit 101, a main unit of an automatic analyzer described later, and a connecting unit for connecting these. In the computer section, a keyboard 103 is used for inputting various data and the like, and a display 102 or a printer 104 is used for displaying or printing measurement results and the like. In the computer main body 101, various calculations, control of various operations and processes, and the like are performed by dedicated programs. Here, the control of the driving means and the like is directly performed by a dedicated sequence controller, and this is controlled by a computer. The connection unit includes a plurality of dedicated interfaces and connection cables, and various types of calculation data, control signals, and the like are transmitted and received through these.

FIG. 2 is an overall view of the main body of the automatic analyzer. A weighing section for sampling, weighing, discharging a sample, automatically supplying a rotor and a funnel is automatically provided on the upper part, and the reagent is added on the lower part. A reaction titrator for reaction, cooling, funnel washing-removal, titration and drainage, a storage unit provided with a container storage tray 91 and tanks 92 at the bottom of the apparatus, and an elevator unit installed on them. It is configured. FIGS. 3 and 4 are plan views of the upper weighing unit and the lower reaction titration unit of the apparatus main body, respectively. FIG. 5 is a developed view of the lower reaction titration unit.

In the present apparatus, a series of operations and processes are performed in parallel on the measuring container 7 held on the outer periphery of the turntable, shifting one step at a time. Therefore, while one measuring container 7 is moved to the next operation position, the other measuring containers 7 are operated and processed. However, for convenience of explanation, a series of operations and operations for only one measuring container 7 is performed. Processing and the like will be described.

The weighing section provided in the upper stage includes a weighing turntable 8, a sampling arm 1, a disposable turntable 9, a suction burette 6, an electronic balance 10, a rotor feeder 11, a funnel feeder 13, and a rotary chuck 15.
(See FIGS. 2 and 3). The weighing turntable 8 has a plurality of holding portions for the sample container 4 and the measurement container 7 arranged concentrically. For example, the sample container 4 is held on the inner side and the measurement container 7 is held on the outer side. This turntable is a computer (upper sequence controller 108a)
(Hereinafter, the same applies to various driving operations in the upper stage) to rotate and move each container to a predetermined position.

The sampling arm 1 is disposed around the weighing turntable 8 and has a handling chuck 2 and a disposable insertion nozzle 3 at its tip. This sampling arm 1 can expand, contract, rotate, and move up and down.
The movement of the sample container 4 and the attachment / detachment and movement of the disposable chip 5 are performed under the control of a computer. Here, the operation of the weighing unit will be described step by step.
To the rotor feeder 11, the funnel 14 to the funnel feeder 13,
The measuring container 7 and the sample container 4 are weighed on a turntable 8
And the disposable chip 5 are set on the disposable turntable 9, respectively.

When the sample container 4 and the measurement container 7 are moved to predetermined positions by rotation of the weighing turntable 8, the sampling arm 1 is lowered and the handling chuck 2 grips the cap portion of the sample container 4. After the sampling arm 1 moves up and moves on the rotary chuck 15, it moves down and the sample container 4 is moved to the rotary chuck 1.
5 holds the container body. At this time, the handling chuck 2 holds the sample container 4 and the lid of the sample container 4 is opened by the rotation of the rotary chuck 15.

The weighing turntable 8 is lowered, the measuring container 7 is set on the electronic balance 10, and the container weight is measured. After the sampling arm 1 moves up and moves onto the disposable turntable 9, it moves down and attaches the disposable sample tip 5 set on the disposable turntable 9 to the disposable insertion nozzle 3. After installation,
The disposable turntable 9 rotates one step for the next supply. Rotary chuck 15 with disposable tip 5
Is moved to the sample container 4 with the lid held by
The tip of the disposable chip 5 is inserted into the sample container 4, and the suction burette 6 is operated by control of a sequence controller (hereinafter, the same applies to various burettes) to aspirate a part of the sample into the disposable chip 5 and collect it. The sampling arm 1 is raised and moved onto the weighing turntable 8, and then lowered to insert the tip of the disposable chip 5 into the measuring container 7, and to operate the suction burette 6 to transfer the sample in the disposable chip 5 to the electronic balance 10. And weigh it.

The density of the sample is determined from the initial collection volume calculated from the expected value and the weighed value, the next sample collection amount is calculated by the computer from the density, and the second suction amount is determined. The suction burette 6 is again operated in the same manner to aspirate the sample into the disposable chip 5, and then the measurement container 7 is similarly operated.
And the amount of the sample collected in the measurement container 7 is weighed. Thus, the target weight can be accurately weighed by sampling twice. The sampling arm 1 is moved onto the chip tray 17, and the disposable chip 5 is discarded there. Further, the lid is closed in the reverse procedure of opening the lid of the sample container 4, and the sample container 4 is returned to the original position.

The weighing turntable 8 is raised again, and the measuring container 7 is removed from the electronic balance 10. The weighing turntable 8 rotates, and the measuring container 7 is moved to a position where the rotor feeder 11 is installed. The rotor feeder 11 is a device that feeds the rotors 12 one by one into the measurement container 7 by making good use of the repulsive force of the magnetic force of the rotor 12.

The weighing turntable 8 rotates again, and the measuring container 7 is moved to the position where the funnel feeder 13 is installed. The funnel feeder 13 sets the funnels 14 one by one on the measuring container 7 under the control of the computer. By setting the funnel 14 in this manner, evaporation of the reagent and the like during the reaction can be prevented. The weighing turntable 8 rotates again, and the measuring container 7 is moved to the position where the elevator 31 is installed.

The elevator section comprises a handling arm 32 having a chuck 33 at the tip and an elevator 31 for moving the same vertically. The chuck 33 can hold the measurement container 7 transferred to the position of the elevator unit, and the handling arm 32 is configured to be extendable. These are also controlled by the computer. The chuck 33 grips the transported measurement container 7 and transports and transfers the measurement container 7 to the lower reaction titration turntable 51 by expansion and contraction of the handling arm 32 and vertical movement of the elevator 31.

The reaction titration section provided in the lower stage includes a reaction titration turntable 51, a reagent addition arm 53, a magnetic stirrer 56, a reaction tank 68, a water addition arm 69, a funnel removal arm 58, a titration electrode arm 60, a titration burette. 64 and a drain arm 67 (see FIGS. 2 and 4). As a preparatory work, a reaction reagent, a solvent, and a titrant are supplied to a tank, and a waste liquid tank and a waste water tank are set.

The reaction titration turntable 51 has holding portions for the measurement containers 7 arranged on the outer periphery, and has a circular funnel collection tray 52 inside thereof. This turntable can be rotated to move each container to a predetermined position under the control of a drive unit by a computer (lower sequence controller 108b) (hereinafter, the same applies to various lower drive operations). Reaction titration turntable 5
1 is provided with a circular hole larger than the measurement container 7 so that the measurement container 7 moves up and down by the operation of the lift 74. At the time of movement, the lift 74 is controlled so as to move up and down to match the height of the lift 74 and the like in the next step. The reagent addition arm 53, the water addition arm 69, the titration electrode arm 60, and the drainage arm 67 are lowered only when a reagent or the like is added, and are raised when the measurement container 7 is moved.

In the reaction titration unit, the measurement container 7 transported from the elevator unit is moved to the position of the reagent addition arm 53. The reagent addition arm 53 includes a reagent addition nozzle 54 and a solvent addition nozzle 55 at the tip of the arm. This moves vertically and horizontally, and reagents and the like are added to the measurement container 7 from both nozzles. At this time, the rotor 12 inside is rotated by the magnetic stirrer 56 installed at the lower part of the turntable to make the sample solution in the measurement container 7 uniform.

The reaction titration turntable 51 rotates, and the measuring container 7 is moved to a position where the reaction tank 68 is installed. The reaction tank 68 is provided below the holding section of the measurement container 7 and has an arc-shaped overflow tank and a spare tank, a circulation pump 73, a plurality of vertically controllable lifts 74, a plurality of magnetic stirrers. 56 (see FIG. 5). The measurement container 7 is immersed in the temperature-controlled reaction tank 68 containing the heat medium by the lowering of the lift 74 to start the reaction. The reaction is carried out while the reaction solution is stirred by a plurality of magnetic stirrers 56 as necessary, and the reaction is stopped by the lift of the lift 74. Here lift 7
The reaction time can be set for each sample by making 4 independently controllable.

The measuring container 7 moved to the position of the water adding arm 69 adds water for hydrolysis to the measuring container 7 from a water adding nozzle 57 provided at the tip. Thereafter, it is immersed again in the reaction tank 68, and the reaction is carried out while being stirred by the magnetic stirrer 56 if necessary. The reaction titration turntable 51 rotates again, and the measurement container 7 is moved to a position where the cooling tank 75 is installed, and is immersed in the cooling tank 75. The reaction titration turntable 51 rotates again, the measuring container 7 is moved to the position of the funnel removing arm 58, and the solvent is added from the solution addition nozzle 59 provided at the tip. The funnel is removed by the funnel removing arm 58 and stirred by the magnetic stirrer 56.

The reaction titration turntable 51 rotates again, and the measuring container 7 is moved to a position where the titration electrode arm 60 is installed. The titration electrode arm 60 is connected to the titration nozzle 6
1. A stirring blade 62 and a titration electrode 63 are provided. This moves up and down, horizontally, and inserts each part into the measuring container 7,
Titration is performed from a titration buret 64 while stirring with a stirring blade 62 and a magnetic stirrer 56. The data at this time is sent to an external computer and output to the display 102 and the printer 104. After completion of the titration, the titration electrode arm 60 is returned to its original position (electrode cleaning tank 76).
Then, the stirring blade 62 and the washing water pump are operated to wash the titration nozzle 61, the stirring blade 62 and the titration electrode 63.

The reaction titration turntable 51 rotates again, and the measuring container 7 is moved to a position where the drainage arm 67 is installed. The drainage arm 67 has a suction nozzle 66 at the tip. This moves up and down, and operates the drain pump 78 to drain the reaction solution in the measurement container 7 into the waste tank in the storage section. The reaction titration turntable 51 rotates again, and the measurement container 7 is moved to the position where the elevator 31 is installed.

The chuck 33 grips the moved measuring container 7 and transports the measuring container 7 to the storage section at the bottom of the apparatus by expanding and contracting the handling arm 32 and moving the elevator 31 up and down. Stored in 91. A plurality of tanks 92 containing reagents, solvents, water, waste liquid, and the like are provided in the storage section.

As described above, by successively performing each operation and process from the upper stage to the lower stage through to the storage of the container at the bottom, all the operations and processes can be automated and the control by the computer is more effective. Has become. In addition, by performing each operation and processing at the bottom in parallel from the upper stage to the lower stage, the analysis of all samples can be speeded up.

[0037]

According to the present invention, in an automatic analyzer for automatically analyzing a plurality of samples unattended, all the operations and processes from the uppermost stage to the lowermost stage and the storage of the containers can be continuously performed, so that all of them can be automated. Since the apparatus has a multi-stage configuration, the apparatus is compact, and the operation and processing of each table are performed in parallel, so that an automatic analyzer having a high processing speed and a large number of processed samples can be provided.

[Brief description of the drawings]

FIG. 1 shows a system configuration diagram of an example of an automatic analyzer according to the present invention.

FIG. 2 is a perspective view specifically illustrating a main body of an example of the automatic analyzer according to the present invention.

FIG. 3 is a plan view showing an upper weighing section of the apparatus main body shown in FIG. 2;

FIG. 4 is a plan view showing a lower reaction titration section of the apparatus main body section shown in FIG. 2;

FIG. 5 is a developed view of a lower reaction titration section of the apparatus main body shown in FIG. 2;

[Explanation of symbols]

 Reference Signs List 1 sampling arm 2 handling chuck 3 dispos insertion nozzle 4 sample container 5 disposable tip 6 suction buret 7 measuring container 8 weighing turntable 9 disposable turntable 10 electronic balance 11 rotor feeder 12 rotor 13 funnel feeder 14 funnel 15 rotary chuck 17 Chip Tray 31 Elevator 32 Handling Arm 33 Chuck 51 Reaction Titration Turntable 52 Funnel Collection Tray 53 Reagent Addition Arm 54 Reagent Addition Nozzle 55 Solvent Addition Nozzle 56 Magnetic Stirrer 57 Water Addition Nozzle 58 Funnel Removal Arm 59 Solvent Addition Nozzle 60 Titration Electrode Arm 61 Titration nozzle 62 Stirrer blade 63 Titration electrode 64 Titration buret 65 Reagent addition nozzle immersion tank 66 Suction nozzle 67 Drainage arm 68 Reaction tank 69 Water addition arm 73 Circulation pump 74 Lift 75 Cooling tank 76 Electrode cleaning tank 78 Drainage pump 91 Container storage tray 92 Tanks 101 Computer body 102 Display 103 Keyboard 104 Printer 105 Interface 106 RS-232C board 107a Upper drive 107b Lower drive Unit 108a Upper sequence controller 108b Lower sequence controller 109a Upper operation panel 109b Lower operation panel 110a Upper power switch 110b Lower power switch 111 Potentiometer 112 Various bullets

────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Yuji Suzuki 3-4-24 Sakaecho, Soka-shi, Saitama Prefecture Lions Plaza Matsubara Housing Complex Room 304 (56) References JP-A-60-252268 (JP, A) JP-A-60 JP-A-49241 (JP, A) JP-A-61-247972 (JP, A) JP-A-55-1551 (JP, A) JP-A-49-48391 (JP, A) JP-A-3-59461 (JP, A) ) Actually open 63-150375 (JP, U) Actually open 56-97740 (JP, U) (58) Fields investigated (Int. Cl. ⁶ , DB name) G01N 35/00-35/10

Claims (1)

(57) [Claims] 1. A automatic analyzer for automatically analyzing a plurality sample while moving the measuring container, table arranged measuring container to be used for movement of the measuring container is a plurality of stages stacked disposed at a predetermined interval, An elevator unit mounted so that a handling arm for grasping the measurement container to move the measurement container between the tables can be moved in the vertical direction, and each device provided to the driving unit and the analysis unit controls the elevator unit. and it is connected coupled to Konpyuta to perform an operation that is configured as capable of performing automatically continuous processing and parallel processing of multiple samples using automated analyzers trial
A method of weighing material, comprising:
Around the weighing turntable placed at the top of the bull
Provided at the tip of the sampling arm
Remove the disposable tip for sampling to the disposable insertion nozzle.
Attach, insert the tip of the disposable chip into the sample container,
The sample in the disposable chip is aspirated and the sample in the disposable chip is
Discharge into the upper measuring container, weigh and determine the density of the sample.
After determining the second suction volume from the density, the sample is again
Aspirate into the disposable tip, then discharge into the measuring vessel,
It is characterized by weighing the amount of sample collected in the measurement container
Of weighing a sample using an automatic analyzer.