JP2920643B2 - Ginkgo biloba extract containing drop - Google Patents
Ginkgo biloba extract containing dropInfo
- Publication number
- JP2920643B2 JP2920643B2 JP1175689A JP17568989A JP2920643B2 JP 2920643 B2 JP2920643 B2 JP 2920643B2 JP 1175689 A JP1175689 A JP 1175689A JP 17568989 A JP17568989 A JP 17568989A JP 2920643 B2 JP2920643 B2 JP 2920643B2
- Authority
- JP
- Japan
- Prior art keywords
- extract
- ginkgo biloba
- drop
- bitterness
- biloba extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000009429 Ginkgo biloba extract Substances 0.000 title claims description 21
- 229940068052 ginkgo biloba extract Drugs 0.000 title claims description 13
- 235000020686 ginkgo biloba extract Nutrition 0.000 title claims description 13
- 235000019658 bitter taste Nutrition 0.000 claims description 22
- 235000013305 food Nutrition 0.000 claims description 12
- 235000016213 coffee Nutrition 0.000 claims description 9
- 235000013353 coffee beverage Nutrition 0.000 claims description 9
- 239000000284 extract Substances 0.000 claims description 9
- 239000000796 flavoring agent Substances 0.000 claims description 7
- 235000013355 food flavoring agent Nutrition 0.000 claims description 7
- 235000003599 food sweetener Nutrition 0.000 claims description 4
- 239000003765 sweetening agent Substances 0.000 claims description 4
- 239000004615 ingredient Substances 0.000 claims description 3
- 235000008100 Ginkgo biloba Nutrition 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 244000194101 Ginkgo biloba Species 0.000 description 6
- 229940106580 ginkgo biloba leaf extract Drugs 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 235000013311 vegetables Nutrition 0.000 description 6
- 229920002472 Starch Polymers 0.000 description 5
- 235000006468 Thea sinensis Nutrition 0.000 description 5
- 235000021552 granulated sugar Nutrition 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- 239000006188 syrup Substances 0.000 description 5
- 235000020357 syrup Nutrition 0.000 description 5
- 244000269722 Thea sinensis Species 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 235000020333 oolong tea Nutrition 0.000 description 3
- 240000000560 Citrus x paradisi Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 235000020279 black tea Nutrition 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 235000020710 ginseng extract Nutrition 0.000 description 2
- 235000009569 green tea Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 108010011485 Aspartame Proteins 0.000 description 1
- 206010065559 Cerebral arteriosclerosis Diseases 0.000 description 1
- 241000218631 Coniferophyta Species 0.000 description 1
- 241000218628 Ginkgo Species 0.000 description 1
- 235000011201 Ginkgo Nutrition 0.000 description 1
- 241000218791 Ginkgoaceae Species 0.000 description 1
- 102220547770 Inducible T-cell costimulator_A23L_mutation Human genes 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000000605 aspartame Substances 0.000 description 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
- 229960003438 aspartame Drugs 0.000 description 1
- 235000010357 aspartame Nutrition 0.000 description 1
- 230000003727 cerebral blood flow Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- -1 flavone glycosides Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 235000015201 grapefruit juice Nutrition 0.000 description 1
- 229940094952 green tea extract Drugs 0.000 description 1
- 235000020688 green tea extract Nutrition 0.000 description 1
- 201000005851 intracranial arteriosclerosis Diseases 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 102200004779 rs2232775 Human genes 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Confectionery (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Tea And Coffee (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Description
【発明の詳細な説明】 ［産業上の利用分野］ 本発明は例えば血流改善作用のあるイチョウ葉エキス
を含有するドロップに関するものであり、特にイチョウ
葉エキスが有する苦味を減じたドロップに関する。Description: TECHNICAL FIELD The present invention relates to, for example, a drop containing a ginkgo biloba extract having a blood flow improving action, and more particularly to a drop having reduced bitterness of the ginkgo biloba extract.
［従来の技術］ イチョウは、イチョウ科（Ginkgoaceae）に属する一
科一属一種の植物で、雌雄異株の裸子植物である。古生
代末期の二畳紀から中性代の三畳紀に発祥し、中生代ジ
ェラ紀に全盛を極め、今日まで植物学的に変化していな
い「生きた化石」と言われる植物である。[Background Art] Ginkgo is a plant belonging to the genus Ginkgoaceae and is a dioecious gymnosperm. It is a "living fossil" plant that originated in the Late Paleozoic from the Permian to the Triassic in the Mesozoic, flourished in the Mesozoic Jerassic, and has not changed botanically until today.
その葉から抽出されるイチョウ葉エキスは、特にドイ
ツで臨床研究が盛んに行われ、末梢血流改善作用が有る
ことが判明し、特に大脳の血流障害や脳動脈硬化に効果
があり、西ドイツ、フランス、韓国では、ボケ等の老人
病に対し有効な医薬品と認められるに至った。Ginkgo biloba extract extracted from the leaves has been actively studied in Germany in particular, and has been found to have a peripheral blood flow improving effect.It is particularly effective for cerebral blood flow disturbance and cerebral arteriosclerosis, In France and Korea, it has been recognized as an effective medicine for geriatric diseases such as blurring.
我国では、薬効の本体であるフラボン配糖体に対する
データの蓄積が充分でなく、医薬品の認可には未だ至っ
ていない。In Japan, the accumulation of data on flavone glycosides, which are the main components of medicinal effects, is not sufficient, and the approval of pharmaceuticals has not yet been achieved.
一方、医薬品として認可されている場合の投与方法が
経口投与であることから、イチョウ葉エキスを機能的食
品として摂取しようとする試みが生されている。On the other hand, since the administration method when approved as a pharmaceutical is oral administration, attempts have been made to take ginkgo biloba extract as a functional food.
［発明が解決しようとする課題］ しかしながら、イチョウ葉エキスは独特の苦味があ
り、錠剤化，カプセル化して摂取する方法以外は行われ
ていなかった。[Problems to be Solved by the Invention] However, Ginkgo biloba leaf extract has a unique bitter taste, and no method other than tableting and encapsulating has been used.
本発明は、イチョウ葉エキスを含有する食品として、
より摂取し易い食品を得ることを目的とする。The present invention, as a food containing ginkgo leaf extract,
The aim is to obtain foods that are easier to consume.
［課題を解決するための手段］ 本発明に係るイチョウ葉エキス含有ドロップでは、イ
チョウ葉エキスを機能性成分とした食品において、前記
食品が甘味料を含んだドロップであり、該ドロップ中に
苦味を有する矯味剤としてコーヒーを含有するものであ
る。[Means for Solving the Problems] In the ginkgo leaf extract-containing drop according to the present invention, in a food containing the ginkgo leaf extract as a functional ingredient, the food is a drop containing a sweetener, and the bitterness is reduced in the drop. It contains coffee as a flavoring agent.
［作用］ 本発明においては、イチョウ葉エキスを機能性成分と
した食品において、前記食品が甘味料を含んだドロップ
であり、該ドロップ中に苦味を有する矯味剤を含有する
ものであるため、イチョウ葉エキスを含有する食品とし
て、より摂取し易い形状となっており、しかもイチョウ
葉エキスの苦味が他の苦味と置かわることにより、口中
で溶かしても、イチョウ葉エキスの苦味が緩和される。[Action] In the present invention, in a food containing ginkgo biloba extract as a functional component, the food is a drop containing a sweetener, and the drop contains a flavoring agent having a bitter taste. As a food containing the leaf extract, it has a shape that is easier to ingest, and the bitterness of the ginkgo leaf extract is alleviated even if it is dissolved in the mouth by placing the bitterness of the ginkgo leaf extract with other bitterness.
添加されるイチョウ葉エキスの好ましい含有量は、一
粒につき0.001g〜0.04gであり、これ以上では、苦味を
有する矯味剤を加えてもイチョウ葉エキスの苦味が隠せ
ないものであることが確認され、これは、西ドイツで医
薬品として認められている一日摂取量の最大1/30程度の
量である。The preferred content of the ginkgo biloba leaf extract to be added is 0.001 g to 0.04 g per grain, and it is confirmed that the ginkgo biloba leaf extract cannot hide the bitterness of a ginkgo biloba leaf extract even if a flavoring agent having a bitterness is added. This is about 1/30 of the daily intake approved as a medicine in West Germany.
また、苦味を有する矯味剤とは、具体的にグレープフ
ルーツ、ウーロン茶、紅茶、人参エキス、緑茶、コーヒ
ー等の自然の苦味風味を有するものでよく、特にコーヒ
ーの有する苦味が最も好ましい結果が確認された。In addition, the flavoring agent having a bitter taste may specifically be one having a natural bitter taste such as grapefruit, oolong tea, black tea, ginseng extract, green tea, coffee, etc. .
また、コーヒーの添加量は、コーヒー抽出乾燥エキス
を添加する場合には、全体の重量の0.5〜６％が良いこ
とが確認された。In addition, it was confirmed that 0.5 to 6% of the total weight of the coffee was good when the dry extract of coffee was added.
［実施例］ 実施例１ 下記の組成により、イチョウ葉エキスを含有するドロ
ップを作成した。[Example] Example 1 A drop containing a ginkgo biloba extract was prepared according to the following composition.
イチョウ葉エキス−24 0.01 g （常磐植物化学製） （実質 0.24mg） マルトース 1.405g （東和化成製） アスパルテーム 0.002g （味の素製） コーヒー抽出乾燥エキス 0.033g （ネッスル日本製） 実施例２ 下記の組成により、イチョウ葉エキスを含有するドロ
ップを作成した。Ginkgo biloba extract-24 0.01 g (manufactured by Tokiwa Vegetable Chemicals) (real 0.24 mg) Maltose 1.405 g (manufactured by Towa Kasei) Aspartame 0.002 g (manufactured by Ajinomoto) Coffee extract dried extract 0.033 g (manufactured by Nestle Japan) Example 2 The following composition As a result, a drop containing a ginkgo biloba extract was prepared.
イチョウ葉エキス−24 0.01 g （常磐植物化学製） （実質 0.24mg） グラニュー糖 0.57 g 水飴 0.93 g コーヒー抽出乾燥エキス 0.025g （ネッスル日本製） 実施例３ 下記の組成により、イチョウ葉エキスを含有するドロ
ップを作成した。Ginkgo biloba extract-24 0.01 g (manufactured by Tokiwa Vegetable Chemicals) (substantially 0.24 mg) Granulated sugar 0.57 g starch syrup 0.93 g dried coffee extract 0.025 g (manufactured by Nestle Japan) Example 3 The following composition contains ginkgo biloba extract Created a drop.
イチョウ葉エキス−24 0.01g （常磐植物化学製） （実質 0.24mg） グラニュー糖 0.57g 水飴 0.93g グレープフルーツ果汁エキス 0.08g 実施例４ 下記の組成により、イチョウ葉エキスを含有するドロ
ップを作成した。Ginkgo biloba extract-24 0.01 g (manufactured by Tokiwa Vegetable Chemicals) (substantially 0.24 mg) Granulated sugar 0.57 g starch syrup 0.93 g grapefruit juice extract 0.08 g Example 4 A drop containing a ginkgo biloba extract was prepared according to the following composition.
イチョウ葉エキス−24 0.01g （常磐植物化学製） （実質 0.24mg） グラニュー糖 0.57g 水飴 0.93g ウーロン茶乾燥エキス 0.05g 実施例５ 下記の組成により、イチョウ葉エキスを含有するドロ
ップを作成した。Ginkgo biloba extract-24 0.01 g (manufactured by Tokiwa Vegetable Chemicals) (substantially 0.24 mg) Granulated sugar 0.57 g starch syrup 0.93 g oolong tea dried extract 0.05 g Example 5 A drop containing a ginkgo biloba leaf extract was prepared according to the following composition.
イチョウ葉エキス−24 0.01g （常磐植物化学製） （実質 0.24mg） グラニュー糖 0.57g 水飴 0.93g 朝鮮人参乾燥エキス 0.10g 実施例６ 下記の組成により、イチョウ葉エキスを含有するドロ
ップを作成した。Ginkgo biloba leaf extract-24 0.01 g (manufactured by Tokiwa Vegetable Chemicals) (substantially 0.24 mg) Granulated sugar 0.57 g starch syrup 0.93 g ginseng dried extract 0.10 g Example 6 A drop containing a ginkgo biloba extract was prepared according to the following composition.
イチョウ葉エキス−24 0.01g （常磐植物化学製） （実質 0.24mg） グラニュー糖 0.57g 水飴 0.93g 緑茶抽出エキス 0.05g 前記実施例１〜実施例６に示した組成によるドロップ
の味覚試験を６名の被験者により行った。Ginkgo biloba extract-24 0.01 g (manufactured by Tokiwa Vegetable Chemicals) (substantially 0.24 mg) Granulated sugar 0.57 g starch syrup 0.93 g green tea extract 0.05 g Six taste tests of drops with the compositions shown in Examples 1 to 6 above. Of subjects.
詳しくは、被験者をブラインドの状態で、ドロップを
含んでもらい、その苦みを４段階に分けてもらった。結
果を次の第１表に示す。Specifically, the subject was asked to include the drop in a blind state, and the bitterness was divided into four stages. The results are shown in Table 1 below.
尚、表中◎は大変良い苦味、○は良い苦味、△は単に
苦い、×は非常に苦いを示す。In the table, ◎ indicates very good bitterness, は indicates good bitterness, Δ indicates simply bitter, and X indicates very bitter.
第１表に示す通り、グレープフルーツ、ウーロン茶、
紅茶、人参エキス、緑茶、コーヒー等の自然の苦味を有
する矯味剤により、イチョウ葉エキスの苦味が緩和され
る。As shown in Table 1, grapefruit, oolong tea,
Bitterness of ginkgo biloba leaf extract is reduced by a flavoring agent having a natural bitterness, such as black tea, ginseng extract, green tea, and coffee.
また、特にコーヒーの有する苦味が最も好ましい結果
が確認された。In addition, it was confirmed that the bitterness of coffee is most preferable.
［発明の効果］ 本発明は以上説明したとおり、イチョウ葉エキスを機
能性成分とした食品において、前記食品が甘味料を含ん
だドロップであり、該ドロップ中に苦味を有する矯味剤
を含有するものであるため、イチョウ葉エキスを含有す
る食品として、より摂取し易い形状となっており、しか
もイチョウ葉エキスの苦味が他の苦味と置かわることに
より、口中で溶かしても、イチョウ葉エキスの苦味が緩
和される等の効果がある。 [Effect of the Invention] As described above, the present invention relates to a food containing ginkgo biloba extract as a functional ingredient, wherein the food is a drop containing a sweetener, and the drop contains a flavoring agent having a bitter taste. Therefore, as a food containing ginkgo leaf extract, it has a shape that is easier to ingest, and because the bitterness of ginkgo leaf extract is placed with other bitterness, even if it is dissolved in the mouth, the bitterness of ginkgo leaf extract Has the effect of alleviating.
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.6 識別記号 ＦＩ Ａ６１Ｋ 35/78 Ａ６１Ｋ 35/78 Ｂ 47/46 47/46 Ｌ (58)調査した分野(Int.Cl.6，ＤＢ名) A23L 1/30 A23G 3/00 101 A23F 5/24 A61K 9/20 A61K 47/46 A61K 35/78 ＪＩＣＳＴファイル（ＪＯＩＳ) ＪＡＦＩＣファイル（ＪＯＩＳ)──────────────────────────────────────────────────の Continued on the front page (51) Int.Cl. 6 identification code FI A61K 35/78 A61K 35/78 B 47/46 47/46 L (58) Investigated field (Int.Cl. 6 , DB name) A23L 1/30 A23G 3/00 101 A23F 5/24 A61K 9/20 A61K 47/46 A61K 35/78 JICST file (JOIS) JAFIC file (JOIS)
Claims (1)
において、 前記食品が甘味料を含んだドロップであり、 該ドロップ中に苦味を有する矯味剤としてコーヒーを含
有することを特徴とするイチョウ葉エキス含有ドロッ
プ。1. A food containing a ginkgo biloba extract as a functional ingredient, wherein the food is a drop containing a sweetener, and the drop contains coffee as a flavoring agent having a bitter taste. Extract containing drop.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1175689A JP2920643B2 (en) | 1989-07-10 | 1989-07-10 | Ginkgo biloba extract containing drop |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1175689A JP2920643B2 (en) | 1989-07-10 | 1989-07-10 | Ginkgo biloba extract containing drop |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0343060A JPH0343060A (en) | 1991-02-25 |
| JP2920643B2 true JP2920643B2 (en) | 1999-07-19 |
Family
ID=16000521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1175689A Expired - Fee Related JP2920643B2 (en) | 1989-07-10 | 1989-07-10 | Ginkgo biloba extract containing drop |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2920643B2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2748331B2 (en) * | 1993-08-04 | 1998-05-06 | アサヒ飲料株式会社 | Ginkgo biloba extract and Omebai extract-containing crude drug extract and health drink containing the crude drug extract |
-
1989
- 1989-07-10 JP JP1175689A patent/JP2920643B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0343060A (en) | 1991-02-25 |
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