JP2945852B2 - Propolis composition - Google Patents
Propolis compositionInfo
- Publication number
- JP2945852B2 JP2945852B2 JP7177954A JP17795495A JP2945852B2 JP 2945852 B2 JP2945852 B2 JP 2945852B2 JP 7177954 A JP7177954 A JP 7177954A JP 17795495 A JP17795495 A JP 17795495A JP 2945852 B2 JP2945852 B2 JP 2945852B2
- Authority
- JP
- Japan
- Prior art keywords
- propolis
- extract
- water
- composition
- lysolecithin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Jellies, Jams, And Syrups (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Description
【０００１】[0001]
【産業上の利用分野】本発明はプロポリス組成物に関す
る。さらに詳しくは水に対する溶解性が優れたプロポリ
ス組成物に関する。The present invention relates to a propolis composition. More particularly, the present invention relates to a propolis composition having excellent solubility in water.
【０００２】[0002]
【従来の技術】プロポリスは蜜蜂の巣等から採取される
樹脂状物質で、その主成分は、フラボノイド類、各種有
機酸やそのエステル類、ミネラル類、ビタミン類等であ
る。プロポリスは抗菌作用、抗酸化作用、制癌作用等が
あることが知られており、健康食品として有用である。
プロポリスはそのまま食するにはあまりにも硬いので、
食用とするには溶液あるいは分散液等の液状とする必要
がある。2. Description of the Related Art Propolis is a resinous substance collected from a honeycomb or the like, and its main components are flavonoids, various organic acids and their esters, minerals, vitamins and the like. Propolis is known to have an antibacterial action, an antioxidant action, an anticancer action and the like, and is useful as a health food.
Propolis is too hard to eat as it is,
In order to make it edible, it is necessary to make it a liquid such as a solution or a dispersion.
【０００３】プロポリスの主成分は上記のようにフラボ
ノイド等大部分が水不溶性の物質であるため、通常は食
品に使用できる溶剤、主としてエタノールの抽出液とし
て用いられる。しかし、高濃度エタノールの抽出液をそ
のまま飲用に供することはできない。そのため、水や果
汁等で希釈して飲用する必要がある。ところが、プロポ
リスのエタノール抽出液を水で希釈した場合は溶解力が
低下しプロポリスの水不溶性成分が析出するという問題
がある。この水不溶性成分はヤニ状でコップ等の容器や
歯に付着し、除去するのが極めて困難である。また、こ
のようなヤニが生じると商品としてのイメージが著しく
損なわれる。[0003] As described above, most of the main components of propolis are water-insoluble substances such as flavonoids. Therefore, propolis is usually used as a solvent that can be used in foods, mainly as an extract of ethanol. However, the extract of high-concentration ethanol cannot be used for drinking as it is. Therefore, it is necessary to dilute with water or fruit juice and drink. However, when the ethanol extract of propolis is diluted with water, there is a problem that the dissolving power is reduced and a water-insoluble component of propolis is precipitated. The water-insoluble component adheres to containers such as cups and teeth and is extremely difficult to remove. Further, when such a tarnish occurs, the image as a product is significantly impaired.
【０００４】プロポリスの水に対する分散性を向上させ
る技術として、例えば特開平２−２４５１５９号公報に
一価アルコールまたは複数個のＯＨ基を有する溶媒に可
溶のプロポリス成分、水素結合し得る複数個のＯＨ基を
含有する媒体およびポリオール・脂肪酸エステル系界面
活性剤からなるプロポリス食品組成物が開示されてい
る。複数個のＯＨ基を含有する媒体としてはグリセリ
ン、エチレングリコール等大部分が合成化学品であり、
健康食品用の添加物としては必ずしも適さない。ポリオ
ール・脂肪酸エステル系界面活性剤も具体的に挙げられ
ているのはグリセリンやエチレングリコール等のエステ
ル類であり、大部分が合成化学品である。天然物由来の
ものでは、複数個のＯＨ基を含有する媒体として水、ソ
ルビット、ショ糖水溶液が、ポリオール・脂肪酸エステ
ル系界面活性剤として大豆レシチンが例示されている。
しかし、これらはプロポリスの分散性を実用的な程度に
向上させることはできず、実施例においてもこれら天然
物のみを用いている例はない。さらに、この技術では、
複数個のＯＨ基含有媒体に予め脂肪酸エステルを混合し
ておいてから、プロポリス抽出液を加える必要があり、
操作が煩雑である。As a technique for improving the dispersibility of propolis in water, for example, JP-A-2-245159 discloses a propolis component soluble in a monohydric alcohol or a solvent having a plurality of OH groups, a plurality of propolis components capable of hydrogen bonding. A propolis food composition comprising a medium containing an OH group and a polyol / fatty acid ester-based surfactant is disclosed. Most of the media containing a plurality of OH groups are synthetic chemicals such as glycerin and ethylene glycol.
It is not always suitable as an additive for health foods. Specific examples of polyol / fatty acid ester surfactants include esters such as glycerin and ethylene glycol, and most are synthetic chemicals. In the case of those derived from natural products, water, sorbitol, and sucrose aqueous solutions are exemplified as a medium containing a plurality of OH groups, and soybean lecithin is exemplified as a polyol / fatty acid ester-based surfactant.
However, they cannot improve the dispersibility of propolis to a practical degree, and there is no example in which only these natural products are used in Examples. Furthermore, with this technology,
It is necessary to mix a fatty acid ester in advance with a plurality of OH group-containing media before adding a propolis extract,
The operation is complicated.
【０００５】また、特開平６−１９７７３４号公報には
プロポリス抽出物とサポニンを含有するプロポリス組成
物が開示されている。しかしながら、この技術はプロポ
リスの分散に関しては必ずしも充分ではない。プロポリ
スのエタノール抽出液を濾過したものにサポニンを加え
ると不溶成分が析出するため、再濾過が必要となり、結
果的に製品の歩留まり率が悪くなる。プロポリスは前述
のように蜜蜂の巣を原料ソースとしており、量的に必ず
しも充分に存在するものではないため、少しの歩留まり
低下も大きな問題である。[0005] Japanese Patent Application Laid-Open No. Hei 6-197834 discloses a propolis composition containing a propolis extract and saponin. However, this technique is not always sufficient with regard to the dispersion of propolis. When saponin is added to the filtered ethanol extract of propolis, insoluble components are precipitated, so that re-filtration is required, and as a result, the yield rate of the product is deteriorated. As described above, since propolis uses a honeycomb as a raw material source and does not necessarily exist in sufficient quantity, a slight decrease in yield is also a major problem.
【０００６】[0006]
【発明が解決しようとする課題】本発明の目的は水に対
する分散性が優れたプロポリス組成物を提供することで
ある。本発明の他の目的は健康食品として適したプロポ
リス組成物を提供することである。SUMMARY OF THE INVENTION An object of the present invention is to provide a propolis composition having excellent water dispersibility. Another object of the present invention is to provide a propolis composition suitable as a health food.
【０００７】[0007]
【課題を解決するための手段】本発明者は上記の問題に
関して鋭意検討の結果、特定の組成のリゾレシチンが、
プロポリスの水に対する分散性を著しく向上させるとい
う事実を見出し、本発明を完成した。すなわち、本発明
はプロポリス抽出物およびリゾリン脂質が９０重量％以
上のリゾレシチンを含有することを特徴とするプロポリ
ス組成物である。以下に本発明を詳細に説明する。Means for Solving the Problems The present inventors have conducted intensive studies on the above problems, and as a result, it has been found that lysolecithin having a specific composition is
The inventors have found that the dispersibility of propolis in water is remarkably improved, and completed the present invention. That is, the present invention is a propolis composition characterized in that the propolis extract and the lysophospholipid contain 90% by weight or more of lysolecithin. Hereinafter, the present invention will be described in detail.
【０００８】本発明のプロポリス抽出物は、原料となる
粗プロポリスの塊、粒、粉末等から溶媒で抽出した成分
である。溶媒としてはプロポリスを溶解するものであれ
ば全て用いることができる。通常は有機溶媒であり、メ
チルアルコール、エチルアルコール、イソプロピルアル
コール、ブチルアルコール等の一価アルコール類、エチ
ルエーテル、メチルエーテル、ジオキサン、テトラヒド
ロフラン等のエーテル類、ギ酸エチル、酢酸エチル等の
エステル類、アセトン、メチルエチルケトン、シクロヘ
キサノン等のケトン類、ベンゼン、トルエン、キシレン
等の芳香族炭化水素、グリセリン、エチレングリコー
ル、ジエチレングリコール、プロピレングリコール、ジ
プロピレングリコール等の多価アルコール類、これら多
価アルコールのエチレンオキサイド、プロピレンオキサ
イド等のアルキレンオキサイド付加物等が挙げられる。
これらの溶媒を最終製品から除かないで用いる場合は食
品添加物として許容されているものであることが必要で
あり、この点でエチルアルコールが好ましい。食品添加
物として認められないものであるときは、最終製品を得
るまでの工程で蒸留等の手段によりこれらの溶媒を除去
する必要がある。The propolis extract of the present invention is a component extracted from a crude propolis lump, granule, powder or the like as a raw material with a solvent. Any solvent can be used as long as it can dissolve propolis. Usually an organic solvent, such as monohydric alcohols such as methyl alcohol, ethyl alcohol, isopropyl alcohol, and butyl alcohol; ethers such as ethyl ether, methyl ether, dioxane and tetrahydrofuran; esters such as ethyl formate and ethyl acetate; and acetone. Ketones such as methyl ethyl ketone and cyclohexanone; aromatic hydrocarbons such as benzene, toluene and xylene; polyhydric alcohols such as glycerin, ethylene glycol, diethylene glycol, propylene glycol and dipropylene glycol; ethylene oxide of these polyhydric alcohols and propylene And alkylene oxide adducts such as oxides.
If these solvents are used without being removed from the final product, they must be acceptable as food additives, and in this regard, ethyl alcohol is preferred. If it is not recognized as a food additive, it is necessary to remove these solvents by means such as distillation in the process until the final product is obtained.
【０００９】本発明で用いるリゾレシチンとはリン脂質
であるレシチンの脂肪酸の１個を加水分解したものの総
称である。通常は酵素により加水分解を行う。酵素とし
てはホスフォリパーゼＡ1が用いられる。このときのレ
シチンからリゾレシチンへの反応率がリゾ化率であり、
リゾリン脂質の含有率として表され、種々の含有率のも
のが製品として販売されている。本発明においてはリゾ
リン脂質の含有率が９０重量％以上のものを用いること
が必要である。リゾリン脂質の含有率が９０重量％未満
では水に対する溶解性が劣り、製品中に不溶性成分が発
生する。[0009] Lysolecithin used in the present invention is a general term for one of the fatty acids of lecithin, which is a phospholipid, hydrolyzed. Usually, hydrolysis is carried out by an enzyme. Enzymes Phospholipase A 1 is used. The reaction rate from lecithin to lysolecithin at this time is the lysification rate,
It is expressed as the content of lysophospholipid, and various contents are sold as products. In the present invention, it is necessary to use a lysophospholipid having a content of 90% by weight or more. When the content of the lysophospholipid is less than 90% by weight, the solubility in water is poor, and an insoluble component is generated in the product.
【００１０】レシチンは卵黄、大豆、酵母等各種のもの
に含まれる。本発明においてリゾレシチンの原料として
用いるものはいずれでもよいが、原料としての入手のし
やすさや食したときの風味等の点から通常は大豆レシチ
ンが用いられる。[0010] Lecithin is contained in various substances such as egg yolk, soybean, yeast and the like. In the present invention, any material may be used as a raw material of lysolecithin, but soybean lecithin is usually used from the viewpoint of easy availability as a raw material and flavor when eaten.
【００１１】リゾレシチン中のリン脂質にはリゾホスフ
ァジルコリン、リゾホスファジルエタノールアミン、リ
ゾホスファジルイノシトール、リゾホスファジン酸等が
含まれる。この中で、リゾホスファジルコリンの含量が
少ないときはリゾレシチンがエタノールに溶けにくくな
り、その結果プロポリス組成物を水で希釈したときに不
溶成分が発生する。従って、製品中にエタノールが含ま
れるときはリゾホスファジルコリンの含量が多いリゾレ
シチンを用いるのがよい。このときの好ましいリゾホス
ファジルコリン含量は５５重量％以上であり、さらに好
ましくは６５重量％以上である。Phospholipids in lysolecithin include lysophosphadylcholine, lysophosphadylethanolamine, lysophosphazilinositol, lysophosphadic acid and the like. Among them, when the content of lysophosphadylcholine is small, lysolecithin is hardly soluble in ethanol, and as a result, an insoluble component is generated when the propolis composition is diluted with water. Therefore, when ethanol is contained in the product, lysolecithin having a high content of lysophosphadylcholine is preferably used. The preferred lysophosphadylcholine content at this time is 55% by weight or more, and more preferably 65% by weight or more.
【００１２】リゾレシチンの量は本発明の目的を達成で
きる範囲であれば特に制限はないが、通常はプロポリス
抽出物の乾燥重量１００部当たり４０〜８０重量部であ
る。４０重量部未満では溶解力が小さく不溶物が析出し
易くなる。８０重量部を越えると効果に頭打ちが見られ
る。The amount of lysolecithin is not particularly limited as long as the object of the present invention can be achieved, but is usually 40 to 80 parts by weight per 100 parts by dry weight of the propolis extract. If the amount is less than 40 parts by weight, the dissolving power is small, and insolubles tend to precipitate. When the amount exceeds 80 parts by weight, the effect reaches a peak.
【００１３】本発明のプロポリス組成物を製造する方法
は代表的には以下のとおりである。まず、原料である粗
プロポリスの塊、粒、粉末等から溶媒で可溶成分を抽出
する。抽出の効率を上げるために粗プロポリスはできる
だけ細かく粉砕したものがよい。抽出温度は特に制限は
ないが、通常は室温から約１００℃である。抽出は溶媒
の沸点以上で行ってもよく、この場合は加圧抽出とな
る。抽出液は濾過等により不溶物と分離する。The method for producing the propolis composition of the present invention is typically as follows. First, a soluble component is extracted with a solvent from lumps, granules, powders, and the like of crude propolis as a raw material. In order to increase the efficiency of extraction, the crude propolis should be ground as finely as possible. The extraction temperature is not particularly limited, but is usually from room temperature to about 100 ° C. The extraction may be performed at a temperature higher than the boiling point of the solvent, and in this case, pressure extraction is performed. The extract is separated from insolubles by filtration or the like.
【００１４】このようにして得たプロポリス抽出液に所
定量のリゾレシチンを添加し混合する。リゾレシチンは
製品形態としてペースト状のもの、粉末状のもの等があ
るが、いずれの形態でも用いることができる。好ましく
は、エチルアルコールに予め溶解して添加するのがよ
い。A predetermined amount of lysolecithin is added to the propolis extract thus obtained and mixed. Lysolecithin may be in the form of a paste, a powder, or the like as a product form, but any form may be used. Preferably, it is better to dissolve in ethyl alcohol in advance and add it.
【００１５】プロポリスの抽出溶媒としてエタノールを
用いた場合は、この段階で最終製品のプロポリス組成物
とすることができる。プロポリス組成物中のプロポリス
成分の濃度に特に制限はないが、粘性等の点から通常は
１〜７０重量％であり、好ましくは１０〜２０重量％で
ある。When ethanol is used as a propolis extraction solvent, a final propolis composition can be obtained at this stage. The concentration of the propolis component in the propolis composition is not particularly limited, but is usually 1 to 70% by weight, preferably 10 to 20% by weight from the viewpoint of viscosity and the like.
【００１６】このプロポリス組成物は透明な液体であ
り、通常他のドリンク原料を含む水溶液に加えてドリン
ク剤としたり、水で希釈して飲用に供するが、希釈して
も不溶成分が発生することがなく、透明性を維持したま
まである。従って容器を汚染したり歯にくっつくような
ことがない。This propolis composition is a transparent liquid and is usually made into a drink in addition to an aqueous solution containing other drink ingredients, or diluted with water for drinking. However, even if diluted, insoluble components are generated. And maintain transparency. Therefore, there is no contamination of the container or sticking to the teeth.
【００１７】なお、必要に応じて溶媒を除去した水溶液
とすることもできる。この場合はプロポリス抽出液とリ
ゾレシチンの組成物にさらに必要量の水を添加した後、
蒸留等の公知の方法で溶媒を除去する。溶媒が除去され
ても液は透明であり、不溶物が析出することはほとんど
ない。It is to be noted that an aqueous solution from which a solvent has been removed may be used if necessary. In this case, after adding the required amount of water to the composition of propolis extract and lysolecithin,
The solvent is removed by a known method such as distillation. Even if the solvent is removed, the liquid is transparent and almost no insoluble matter is deposited.
【００１８】本発明のプロポリス組成物は以上のように
プロポリス抽出物とリゾリン脂質含量が９０重量％のリ
ゾレシチンよりなり、必要に応じてエタノール、水を含
むが、さらに目的に応じて本発明の目的を損なわない限
り他の添加物を含有して差し支えない。これらの物とし
て、例えば天然香料や健康食品素材等が挙げられる。As described above, the propolis composition of the present invention comprises a propolis extract and lysolecithin having a lysophospholipid content of 90% by weight, and contains ethanol and water as required. May be contained as long as the other additives are not impaired. These include, for example, natural flavors and health food materials.
【００１９】[0019]
【作用】本発明においてはプロポリス抽出物にリゾリン
脂質含量が９０重量％のリゾレシチンを加えることによ
り、プロポリス抽出物の水に対する分散性を著しく向上
させるという顕著な効果を奏する。この理由は必ずしも
明らかではない。リゾレシチンは油溶性の部分と親水性
の部分を同一分子内に有しており、界面活性剤としての
作用が大きいと考えられる。従ってリゾレシチンは水中
でミセルを作って会合し、水不溶性のプロポリスはミセ
ル中に取り込まれて安定に存在しているのではないかと
思われる。ただし、リゾレシチンは他の界面活性剤的作
用を有するものに比較してもプロポリスの分散効果は大
きく、必ずしも上記のように一義的に説明がつくもので
はないが、いずれにしろそのプロポリス分散効果は驚く
べきものである。In the present invention, the addition of lysolecithin having a lysophospholipid content of 90% by weight to the propolis extract has a remarkable effect of remarkably improving the dispersibility of the propolis extract in water. The reason for this is not always clear. Lysolecithin has an oil-soluble portion and a hydrophilic portion in the same molecule, and is considered to have a large effect as a surfactant. Therefore, it seems that lysolecithin forms micelles in water and associates with each other, and that water-insoluble propolis is stably incorporated by being incorporated into micelles. However, lysolecithin has a greater propolis dispersing effect than other surfactant-active agents, and is not necessarily uniquely described as described above. That's amazing.
【００２０】[0020]
【実施例】以下、本発明を実施例で説明するが、本発明
はこれらの実施例によって限定される物ではない。EXAMPLES The present invention will be described below with reference to examples, but the present invention is not limited to these examples.
【００２１】実施例１ ブラジル産プロポリス原塊１ｋｇを粉砕し、これに食品
用エタノール（９５％）３ｌを添加し、室温で時々攪拌
を行いながら３カ月間放置した後、Ｎｏ．５Ｃ濾紙で濾
過してプロポリス抽出液２．７ｌを得た。この抽出液中
のプロポリス成分は０．４ｋｇであった。このプロポリ
ス抽出液５０ｍｌに大豆リゾレシチンＳＬＰ−ＬＰＣ７
０（リゾホスファジルコリン７０％、リゾ化率９０％、
ツル−レシチン工業株式会社製）を５ｇ添加し、マグネ
チックスターラーで攪拌し、プロポリス組成液を得た。
このプロポリス組成液は褐色の透明液で、プロポリス抽
出液と外観は変わらなかった。このプロポリス組成液を
水に滴下して攪拌しても不溶物は発生せず、液は透明で
あった。Example 1 1 kg of an original Brazilian propolis mass was pulverized, 3 l of ethanol for food (95%) was added thereto, and the mixture was allowed to stand at room temperature for 3 months with occasional stirring. Filtration through a 5C filter paper provided 2.7 l of propolis extract. The propolis component in this extract was 0.4 kg. Soybean lysolecithin SLP-LPC7 was added to 50 ml of this propolis extract.
0 (lysophosphadylcholine 70%, lysoification ratio 90%,
5g (Tul-Lecithin Industry Co., Ltd.) was added and stirred with a magnetic stirrer to obtain a propolis composition liquid.
This propolis composition liquid was a brown transparent liquid, and the appearance was not different from that of the propolis extract. Even when the propolis composition liquid was dropped into water and stirred, no insolubles were generated, and the liquid was transparent.
【００２２】実施例２ 中国産プロポリス原塊１ｋｇを粉砕し、これに食品用エ
タノール（９５％）３ｌを添加し、室温で時々攪拌を行
いながら３カ月間放置した後、Ｎｏ．５Ｃ濾紙で濾過し
てプロポリス抽出液３．０ｌを得た。この抽出液中のプ
ロポリス成分は０．６ｋｇであった。このプロポリス抽
出液５０ｍｌに大豆リゾレシチンＳＬＰ−ＬＰＣ７０を
５ｇ添加し、マグネチックスターラーで攪拌し、プロポ
リス組成液を得た。このプロポリス組成液は褐色の透明
液で、プロポリス抽出液と外観は変わらなかった。この
プロポリス組成液を水に滴下して攪拌しても不溶物は発
生せず、液は透明であった。Example 2 1 kg of raw Chinese propolis mass was pulverized, 3 l of ethanol for food (95%) was added thereto, and the mixture was allowed to stand at room temperature for 3 months with occasional stirring. Filtration through 5C filter paper gave 3.0 liters of propolis extract. The propolis component in this extract was 0.6 kg. 5 g of soybean lysolecithin SLP-LPC70 was added to 50 ml of this propolis extract and stirred with a magnetic stirrer to obtain a propolis composition solution. This propolis composition liquid was a brown transparent liquid, and the appearance was not different from that of the propolis extract. Even when the propolis composition liquid was dropped into water and stirred, no insolubles were generated, and the liquid was transparent.
【００２３】比較例１ 実施例１と同様にしてプロポリス抽出液を得た。このプ
ロポリス抽出液５０ｍｌに大豆レシチンＳＬＰ−ＰＣ７
０（ホスファジルコリン７０％、ツル−レシチン工業株
式会社製）を５ｇ添加し、マグネチックスターラーで攪
拌し、プロポリス組成液を得た。このプロポリス組成液
はプロポリス抽出液と外観は変わらなかったが、水に滴
下するとヤニ状の不溶成分が発生した。この不溶成分は
ポリ容器の壁に付着し洗浄が困難であった。Comparative Example 1 A propolis extract was obtained in the same manner as in Example 1. Soy lecithin SLP-PC7 was added to 50 ml of this propolis extract.
0 (70% phosphadylcholine, manufactured by Tsuru-Lecithin Industry Co., Ltd.) was added, and the mixture was stirred with a magnetic stirrer to obtain a propolis composition liquid. The appearance of this propolis composition was not different from that of the propolis extract, but when dropped into water, a tar-like insoluble component was generated. This insoluble component adhered to the wall of the plastic container and was difficult to clean.
【００２４】比較例２ 実施例１と同様にしてプロポリス抽出液を得た。このプ
ロポリス抽出液５０ｍｌに大豆レシチンＳＬＰ−ＰＣ７
０を５ｇおよび蒸留水２０ｍｌを添加し、マグネチック
スターラーで攪拌したところ、液が白濁した。これをＮ
ｏ．５Ｃ濾紙で濾過してプロポリス組成液を得た。この
プロポリス組成液はプロポリス抽出液と外観は変わらな
かったが、水に滴下するとヤニ状の不溶成分が発生し
た。この不溶成分はポリ容器の壁に付着し洗浄が困難で
あった。Comparative Example 2 A propolis extract was obtained in the same manner as in Example 1. Soy lecithin SLP-PC7 was added to 50 ml of this propolis extract.
0 g and 20 ml of distilled water were added, and the mixture was stirred with a magnetic stirrer. This is N
o. The mixture was filtered through a 5C filter paper to obtain a propolis composition liquid. The appearance of this propolis composition was not different from that of the propolis extract, but when dropped into water, a tar-like insoluble component was generated. This insoluble component adhered to the wall of the plastic container and was difficult to clean.
【００２５】参考例１ 実施例１と同様にしてプロポリス抽出液を得た。このプ
ロポリス抽出液５０ｍｌに大豆リゾレシチンＳＬＰ−ホ
ワイトリゾ（リゾホスファジルコリン２０％、ツル−レ
シチン工業株式会社製）を５ｇ添加し、マグネチックス
ターラーで攪拌したところ、不溶成分が液中に認められ
た。これをＮｏ．５Ｃ濾紙で濾過してプロポリス組成液
を得た。このプロポリス組成液はプロポリス抽出液と外
観は変わらなかったが、水に滴下するとヤニ状の不溶成
分が発生した。この不溶成分はポリ容器の壁に付着し洗
浄が困難であった。Reference Example 1 A propolis extract was obtained in the same manner as in Example 1. To 50 ml of this propolis extract was added 5 g of soybean lysolecithin SLP-white lyso (lysophosphadylcholine 20%, manufactured by Tsuru-Lecithin Industry Co., Ltd.), and the mixture was stirred with a magnetic stirrer. As a result, insoluble components were found in the liquid. . This is No. The mixture was filtered through a 5C filter paper to obtain a propolis composition liquid. The appearance of this propolis composition was not different from that of the propolis extract, but when dropped into water, a tar-like insoluble component was generated. This insoluble component adhered to the wall of the plastic container and was difficult to clean.
【００２６】参考例２ 実施例１と同様にしてプロポリス抽出液を得た。このプ
ロポリス抽出液５０ｍｌに卵黄リゾレシチンＬＰＬ−２
０（リゾホスファジルコリン２０％、リゾ化率９０％以
上、キューピー株式会社製）を５ｇ添加し、マグネチッ
クスターラーで攪拌したところ、不溶成分が液中に認め
られた。これをＮｏ．５Ｃ濾紙で濾過してプロポリス組
成液を得た。このプロポリス組成液はプロポリス抽出液
と外観は変わらなかったが、風味が悪く、また水に滴下
するとヤニ状の不溶成分が発生した。この不溶成分はポ
リ容器の壁に付着し洗浄が困難であった。Reference Example 2 A propolis extract was obtained in the same manner as in Example 1. Egg yolk lysolecithin LPL-2 was added to 50 ml of this propolis extract.
When 5 g of 0 (lysophosphadylcholine, 20% lyso conversion, 90% or more, manufactured by Kewpie Co., Ltd.) was added and stirred with a magnetic stirrer, an insoluble component was found in the liquid. This is No. The mixture was filtered through a 5C filter paper to obtain a propolis composition liquid. Although the appearance of this propolis composition solution was not different from that of the propolis extract solution, it had a poor flavor, and when dropped into water, a tar-like insoluble component was generated. This insoluble component adhered to the wall of the plastic container and was difficult to clean.
【００２７】比較例３ 実施例１と同様にしてプロポリス抽出液を得た。このプ
ロポリス抽出液５０ｍｌにキラヤサポニン キラヤニン
Ｃ−１００（キラヤ抽出物２５％、丸善化成株式会社
製）を５ｍｌ添加し、マグネチックスターラーで攪拌し
たところ、液が白濁した。これをＮｏ．５Ｃ濾紙で濾過
してプロポリス組成液を得た。このプロポリス組成液は
プロポリス抽出液と外観は変わらなかったが、水に滴下
するとヤニ状の不溶成分が発生した。この不溶成分はポ
リ容器の壁に付着し洗浄が困難であった。Comparative Example 3 A propolis extract was obtained in the same manner as in Example 1. To 50 ml of this propolis extract, 5 ml of Kiraya Saponin Kirayanin C-100 (Kiraya extract 25%, manufactured by Maruzen Kasei Co., Ltd.) was added, and the mixture was stirred with a magnetic stirrer. This is No. The mixture was filtered through a 5C filter paper to obtain a propolis composition liquid. The appearance of this propolis composition was not different from that of the propolis extract, but when dropped into water, a tar-like insoluble component was generated. This insoluble component adhered to the wall of the plastic container and was difficult to clean.
【００２８】[0028]
【発明の効果】以上の実施例、比較例、参考例より本発
明の効果は明らかである。即ち、リゾ化していないレシ
チンを用いた比較例１、２、キラヤサポニンを用いた比
較例３では水に滴下するとヤニ状の不溶成分が発生す
る。また、リゾホスファジルコリン含量が少ないと、エ
タノールが溶媒である場合やはり水で希釈すると不溶成
分が発生する。これに対して、リゾ化率が９０％以上
（即ちリゾリン脂質が９０％以上）でそのうちリゾホス
ファジルコリン含量が５５％以上の実施例１、２におい
てはプロポリス組成液は透明で、水に滴下しても不溶成
分は発生しない。The effects of the present invention are evident from the above Examples, Comparative Examples and Reference Examples. That is, in Comparative Examples 1 and 2 using lecithin that has not been lysed, and Comparative Example 3 using Kirayasaponin, a tar-like insoluble component is generated when dropped into water. When the content of lysophosphadylcholine is low, when ethanol is used as a solvent, an insoluble component is generated when the solvent is diluted with water. On the other hand, in Examples 1 and 2 in which the lysolysis rate was 90% or more (that is, the lysophospholipid was 90% or more) and the lysophosphadylcholine content was 55% or more, the propolis composition solution was transparent and dropped into water No insoluble components are generated.
───────────────────────────────────────────────────── フロントページの続き (58)調査した分野(Int.Cl.6，ＤＢ名) A23L 1/076 A23L 1/30 ＪＩＣＳＴファイル（ＪＯＩＳ)──────────────────────────────────────────────────続 き Continued on the front page (58) Field surveyed (Int.Cl. 6 , DB name) A23L 1/076 A23L 1/30 JICST file (JOIS)
Claims (2)
９０重量％以上のリゾレシチンを含有することを特徴と
するプロポリス組成物。1. A propolis composition characterized in that the propolis extract and the lysophospholipid contain 90% by weight or more of lysolecithin.
ン含量が５５重量％以上のリゾレシチンを含有すること
を特徴とするプロポリス組成物。2. A propolis composition comprising lysolecithin having a lysophosphidylcholine content of 55% by weight or more in lysophospholipids.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7177954A JP2945852B2 (en) | 1995-06-22 | 1995-06-22 | Propolis composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7177954A JP2945852B2 (en) | 1995-06-22 | 1995-06-22 | Propolis composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH09180A JPH09180A (en) | 1997-01-07 |
| JP2945852B2 true JP2945852B2 (en) | 1999-09-06 |
Family
ID=16039994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7177954A Expired - Lifetime JP2945852B2 (en) | 1995-06-22 | 1995-06-22 | Propolis composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2945852B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017089842A1 (en) * | 2015-11-23 | 2017-06-01 | Apivita S.A. | Method for preparing a stable controlled-release propolis colloidal dispersion system for various uses |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5352961B2 (en) * | 2006-03-28 | 2013-11-27 | Ｊｎｃ株式会社 | Life-style related diseases prevention / treatment agents |
| JP5528786B2 (en) | 2009-12-09 | 2014-06-25 | 矢崎総業株式会社 | Crimp terminal with electric wire and curing method of coating agent |
| JP6101854B1 (en) * | 2016-10-14 | 2017-03-22 | アピ株式会社 | Propolis extract-containing composition for capsule and capsule |
-
1995
- 1995-06-22 JP JP7177954A patent/JP2945852B2/en not_active Expired - Lifetime
Non-Patent Citations (1)
| Title |
|---|
| 日本農芸化学会誌 第６４巻 第８号（１９９０）ｐ．１３５５−１３６０ |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017089842A1 (en) * | 2015-11-23 | 2017-06-01 | Apivita S.A. | Method for preparing a stable controlled-release propolis colloidal dispersion system for various uses |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH09180A (en) | 1997-01-07 |
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