JP3029266B2 - Osteosynthesis material - Google Patents
Osteosynthesis materialInfo
- Publication number
- JP3029266B2 JP3029266B2 JP1315560A JP31556089A JP3029266B2 JP 3029266 B2 JP3029266 B2 JP 3029266B2 JP 1315560 A JP1315560 A JP 1315560A JP 31556089 A JP31556089 A JP 31556089A JP 3029266 B2 JP3029266 B2 JP 3029266B2
- Authority
- JP
- Japan
- Prior art keywords
- present
- bone
- treatment
- fitted
- fracture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
- A61F2002/30235—Three-dimensional shapes cylindrical tubular, e.g. sleeves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
Description
【発明の詳細な説明】 （産業上の利用分野） 本発明は、骨折の治療、特に事故等によって生じた複
雑な骨折に対し、好適に適用できる骨接合材の提供に関
する。Description: TECHNICAL FIELD The present invention relates to the treatment of fractures, and more particularly to the provision of an osteosynthesis material that can be suitably applied to complicated fractures caused by accidents and the like.
（従来技術） 従来、骨折治療に対しては、当該部をピン、プレー
ト、ネジ、ビス、スクリュー等でつなぎ合せて固定する
方法が用いられている。(Prior Art) Conventionally, for the treatment of fractures, a method of connecting and fixing the relevant portions with pins, plates, screws, screws, screws, or the like has been used.
（発明が解決しようとする問題点） しかしながら、かかる従来法によると、骨折断面が複
雑な、例えば事故等によって生じた骨折に対しては接
合、修復に時間がかかり、また、高度な技術を要する等
の問題を生じた。(Problems to be Solved by the Invention) However, according to such a conventional method, it takes a long time to join and repair a fracture having a complicated fracture section, for example, a fracture caused by an accident or the like, and requires a high level of technology. And other problems.
また、かかる治療用具には相当の強度が要求されるこ
とから金属、アルミナセラミック等の素材が使用され、
治癒後には再手術によって体内から取り出したり、或は
体内に留め置いても弾性不足のため骨に馴染みにくい等
の欠点も有した。In addition, since such treatment tools require considerable strength, materials such as metals and alumina ceramics are used.
Even after healing, it has a drawback that it is difficult to adjust to bone due to lack of elasticity even if it is removed from the body by reoperation or kept inside the body.
また、生体吸収性材料をその素材とする用具の提案も
なされているが、低強度の欠点が解消されず実用化に至
っていない。In addition, although a tool using a bioabsorbable material as the material has been proposed, the drawback of low strength has not been solved and practical use has not been achieved.
（発明が解決しようとする問題点） 本発明は、かかる点、治療の容易性と治療効果を高
め、また、強度的にもその適用に耐え得る新規な生体吸
収性骨接合材を提供したものである。(Problems to be Solved by the Invention) The present invention provides a novel bioabsorbable osteosynthesis material which enhances such points, ease of treatment and therapeutic effect, and can withstand its application in strength. It is.
（問題を解決するための手段） しかるに、本発明はその構成において、生体内分解吸
収性の医用材料を以って筒状に構成され、且つ、その長
さ方向にこれを開口させるための切欠部を設けたことに
特徴を有する骨接合材の提供に関する。(Means for Solving the Problems) However, in the present invention, the present invention is configured to have a tubular shape made of a biodegradable and absorbable medical material, and to have a cutout for opening the same in the longitudinal direction thereof. The present invention relates to the provision of an osteosynthesis material characterized by providing a portion.
（作用） 本発明は、その素材として生体内分解吸収性の医用材
料を以って構成したので、術後において体内から取り出
す必要が全くなく、また、治療に当ってはこれを当該部
に被嵌させ、固定させるという極めて簡単な操作である
ため高度な技術も熟練も要しない利点がある。(Action) Since the present invention is made of a biodegradable and absorbable medical material as its material, there is no need to remove it from the body after surgery, and it is applied to the part during treatment. Since it is a very simple operation of fitting and fixing, there is an advantage that advanced technology and skill are not required.
更に、円筒状という形状により、これを被嵌、適用し
たとき形状の特殊性により強度が格段に向上するという
特徴も有する。Furthermore, the cylindrical shape has a feature that the strength is remarkably improved due to the specialness of the shape when fitted and applied.
以下、その構成について例を挙げて説明する。 Hereinafter, the configuration will be described with an example.
（構成例） 第１図〜第３図は本発明の構成を例示したもので、第
１図に示すものは筒状体（１）の長さ方向に平行に切欠
部（２）を設けた例を、また、第２図には同様の筒状体
（１）の長さ方向に斜めに切欠部（２）を設けた例を、
更に第３図には上縁と重なり合った切欠部（２）を設け
た例を示した。かかる筒状体は生体内において分解、吸
収される、ポリラクチド、ポリグリコリド、ポリラクチ
ドとポリグリコリドの共重合体、パラジオキサノン、カ
プロラクタム、コラーゲン等の医療用素材を以って構成
され、これの筒状化に際しては0.5ミリ〜数ミリの厚さ
のシートを丸めて円筒状に成型したり、棒状のものの中
心をくりぬいたり、押出し成型等によって構成される。(Structure Example) FIGS. 1 to 3 exemplify the structure of the present invention. The structure shown in FIG. 1 is provided with a cutout (2) parallel to the length direction of the tubular body (1). FIG. 2 shows an example in which a notch (2) is provided diagonally in the length direction of a similar cylindrical body (1).
Further, FIG. 3 shows an example in which a notch (2) overlapping the upper edge is provided. Such a tubular body is composed of a medical material such as polylactide, polyglycolide, a copolymer of polylactide and polyglycolide, paradioxanone, caprolactam, and collagen, which are decomposed and absorbed in a living body. When shaping, a sheet having a thickness of 0.5 mm to several mm is rolled and formed into a cylindrical shape, the center of a rod-shaped material is cut out, or extrusion molding is performed.
切欠部（２）はこれを径方向に押し広げて開口させ、
骨に嵌合させるために設けたもので、その長さ方向全長
にわたって図例のように様々な形態で設ける。The notch (2) pushes this radially open to open it,
It is provided for fitting into a bone, and is provided in various forms as shown in the figure over the entire length in the length direction.
かかる切欠部は、例えば骨に被嵌させたときに血流を
妨げないために全周に対し約1/3の空隙となるよう成型
し、或は骨に対して適用するのが望ましい。For example, it is desirable to form the cutout so as to have a space of about 1/3 of the entire circumference so as not to impede blood flow when fitted to the bone, or to apply the cutout to the bone.
尚、第１図における（３）は貫通孔を示し、骨と固定
させるための糸（７）を挿通させるために設けたもので
ある。In addition, (3) in FIG. 1 indicates a through hole, which is provided for inserting a thread (7) for fixing to a bone.
本発明はかかる構成において、第４図にその適用例を
示すように、複雑骨折した骨（４）（５）をその骨折部
（６）で接合した後、当該部に本発明に係わる筒状体
（１）被嵌させ、貫通孔（３）に対応する骨（４）
（５）に孔をあけ、ここより前記したのと同様の生体吸
収性材料にて構成された糸（７）を挿通し、これを縛っ
て固定するものである。尚、骨折部（６）への筒状体
（１）の被嵌は切欠部（２）を径方向に押し広げて当該
部に被せるもので、被嵌後は素材の持つ弾性によって骨
が被覆された外観を呈する。In the present invention, as shown in an application example in FIG. 4, a complicated fractured bone (4) (5) is joined at its fracture part (6), and then the cylindrical part according to the present invention is attached to the fractured part (6). Body (1) Fitted and bone (4) corresponding to through hole (3)
A hole is made in (5), and a thread (7) made of the same bioabsorbable material as described above is inserted therethrough, tied and fixed. The tubular body (1) is fitted to the fractured part (6) by pushing the notch (2) in the radial direction to cover the part. After the fitted, the bone is covered by the elasticity of the material. It has a given appearance.
このような操作によって治療は完了し、その後は当該
部が治癒するまで放置すれば、即ち、治癒とともに適用
した用具は消滅するのでその後の処置は一切不要とな
る。The treatment is completed by such an operation, and after that, if the part is left to heal, that is, the tool applied with the healing disappears, so that no further treatment is required.
本発明における筒状体の素材、サイズ、厚さ等は適用
箇所によって任意であるが、特に、予後の経過から数ヵ
月にわたってその強力の維持が可能なd,d1,1等各種タイ
プのポリラクチド及びこれの共重合体、ポリグリコール
酸等との共重合体が最適である。また、かかる素材は延
伸等の手段によって、また、異素材との複合化によって
強度アップされたものが好適である。The material, size, thickness, etc., of the cylindrical body in the present invention are arbitrary depending on the application site. Optimum is a copolymer thereof, a copolymer with polyglycolic acid or the like. It is preferable that the strength of the material is increased by stretching or the like, or by compounding with a different material.
尚、筒状体の被嵌後は前記したように、貫通孔より骨
にあけた孔に生体吸収性の糸、或は金属線を挿通して縛
るなり、単に筒状体の全周を同様の素材で縛るなり、生
体吸収性材料にて構成されたネジ、ボルト、ナット等で
固定するなりその固定法は任意である。After the cylindrical body is fitted, as described above, a bioabsorbable thread or a metal wire is inserted into the hole formed in the bone from the through hole and tied. And fixed with screws, bolts, nuts, etc. made of a bioabsorbable material. The fixing method is arbitrary.
（発明の効果） 本発明は以上のように、極めて簡単にその処置が行な
え、また、格別高度な技術を要することなく、しかも短
時間の内にかかる治療が行なえるため患者に苦痛を与え
ることがなく、予後の経過も極めて良好である。(Effects of the Invention) As described above, the present invention can perform the treatment extremely easily, and does not require specially advanced technology, and can perform the treatment in a short time, thereby causing pain to the patient. And the prognosis is very good.
また、円筒状という特殊な形状であるので、これを被
嵌、固定したときプレート状、ピン状のものと比較にな
らないほど強度が向上し、また、外力に対しても極めて
安定で、ズレたり、外れたりすることがない等治療上必
要な特徴も備える。In addition, since it has a special shape called a cylindrical shape, when it is fitted and fixed, its strength is improved so that it cannot be compared with a plate-shaped or pin-shaped one, and it is extremely stable against external forces, It also has features necessary for treatment, such as no detachment.
よって、本発明は特にその骨折の状態が複雑な事故等
による骨折部位への適用はもとより、他の外科手術等に
よって切断された骨どうしの接合、修復等にも好適に適
用できるものである。Therefore, the present invention can be suitably applied not only to a fracture site caused by an accident or the like having a complicated fracture state, but also to joining or repairing bones cut by another surgical operation or the like.
第１図〜第３図は本発明の構成を例示した斜視図。第４
図は本発明接合材を骨折部へ適用した例を示す斜視図。 （１）……筒状体、（２）……切欠部 （４）（５）……骨1 to 3 are perspective views illustrating the configuration of the present invention. 4th
The figure is a perspective view which shows the example which applied the joining material of this invention to a fracture part. (1) ... cylindrical body, (2) ... notch (4) (5) ... bone
───────────────────────────────────────────────────── フロントページの続き 審査官 石川 太郎 (56)参考文献 特開 昭60−88543（ＪＰ，Ａ) 特開 昭64−32855（ＪＰ，Ａ) 特開 昭48−19087（ＪＰ，Ａ) 特開 昭59−203550（ＪＰ，Ａ) 特開 昭62−227351（ＪＰ，Ａ) 実開 昭59−119835（ＪＰ，Ｕ) 特表 平３−505537（ＪＰ，Ａ) 国際公開87／6843（ＷＯ，Ａ１) 国際公開88／6872（ＷＯ，Ａ１) 西独国特許出願公開255408（ＤＥ，Ａ １) 西独国特許出願公開3042003（ＤＥ, Ａ１) (58)調査した分野(Int.Cl.7，ＤＢ名) A61B 17/56 - 17/92 A61F 2/28 A61L 27/00 ────────────────────────────────────────────────── ─── Continuation of the front page Examiner Taro Ishikawa (56) References JP-A-60-88543 (JP, A) JP-A 64-32855 (JP, A) JP-A 48-19087 (JP, A) JP-A-59-203550 (JP, A) JP-A-62-227351 (JP, A) JP-A-59-119835 (JP, U) Japanese Translation of PCT International Publication No. 3-505537 (JP, A) , A1) WO 88/6872 (WO, A1) West German Patent Application 255,408 (DE, A1) West German Patent Application 3042003 (DE, A1) (58) Fields investigated (Int. Cl. 7 , DB A61B 17/56-17/92 A61F 2/28 A61L 27/00
Claims (1)
用具であって、厚さ0.5ミリ〜数ミリの生体内分解吸収
性高分子のシート状体を以って筒状に構成され、その長
さ方向にこれを開口させるための切欠部を設けたことを
特徴とする骨接合材。1. A tool for fixing a fractured portion by fitting it from the outside, comprising a sheet of a biodegradable and absorbable polymer having a thickness of 0.5 to several millimeters. An osteosynthesis material, which is constituted and provided with a cutout for opening the same in the longitudinal direction.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1315560A JP3029266B2 (en) | 1989-12-04 | 1989-12-04 | Osteosynthesis material |
| DE4118201A DE4118201C2 (en) | 1989-12-04 | 1991-06-03 | Device for joining bones |
| US07/961,193 US5275602A (en) | 1989-12-04 | 1992-10-14 | Bone-joining articles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1315560A JP3029266B2 (en) | 1989-12-04 | 1989-12-04 | Osteosynthesis material |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH03176066A JPH03176066A (en) | 1991-07-31 |
| JP3029266B2 true JP3029266B2 (en) | 2000-04-04 |
Family
ID=18066816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1315560A Expired - Lifetime JP3029266B2 (en) | 1989-12-04 | 1989-12-04 | Osteosynthesis material |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP3029266B2 (en) |
| DE (1) | DE4118201C2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3406272A1 (en) | 2015-01-26 | 2018-11-28 | Ube Industries, Ltd. | Cell culture method using bone marrow-like structure, and porous polymide film for healing bone injury site |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4313192C1 (en) * | 1993-04-22 | 1994-09-15 | Kirsch Axel | Cuff for accelerating healing of bone defects |
| ATE169809T1 (en) * | 1993-05-21 | 1998-09-15 | Biovision Gmbh | ANASTOMOTIS DEVICE |
| IT1279721B1 (en) * | 1995-12-22 | 1997-12-16 | Istituti Ortopedici Rizzoli | ORTHOPEDIC PROSTHETIC DEVICE |
| EP2737875B1 (en) | 2010-11-15 | 2015-09-23 | Synthes GmbH | Graft collection and containment system for bone defects |
| JP5807885B1 (en) * | 2014-09-24 | 2015-11-10 | 圓井繊維機械株式会社 | Bone fixing device and manufacturing method thereof |
| US10258472B2 (en) * | 2015-03-31 | 2019-04-16 | DePuy Synthes Products, Inc. | Bone graft cage |
| US10695181B2 (en) | 2016-02-16 | 2020-06-30 | DePuy Synthes Products, Inc. | Bone graft cage |
| AU2017286289B2 (en) | 2016-06-13 | 2021-06-24 | DePuy Synthes Products, Inc. | Bone graft cage |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3042003A1 (en) | 1980-10-10 | 1982-07-15 | Hans Dr. 5609 Hückeswagen Reimer | Bone cement reinforcing component - comprises thread structure compatible with body tissue forming soft sponge |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI81010C (en) * | 1986-09-05 | 1990-09-10 | Biocon Oy | Benomplaceringsimplants |
| JPS6368155A (en) * | 1986-09-11 | 1988-03-28 | グンゼ株式会社 | Bone bonding pin |
| DE8804423U1 (en) * | 1988-04-02 | 1989-08-03 | Beiersdorf Ag, 20253 Hamburg | Tubular implant |
-
1989
- 1989-12-04 JP JP1315560A patent/JP3029266B2/en not_active Expired - Lifetime
-
1991
- 1991-06-03 DE DE4118201A patent/DE4118201C2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3042003A1 (en) | 1980-10-10 | 1982-07-15 | Hans Dr. 5609 Hückeswagen Reimer | Bone cement reinforcing component - comprises thread structure compatible with body tissue forming soft sponge |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3406272A1 (en) | 2015-01-26 | 2018-11-28 | Ube Industries, Ltd. | Cell culture method using bone marrow-like structure, and porous polymide film for healing bone injury site |
| US10508264B2 (en) | 2015-01-26 | 2019-12-17 | Ube Industries, Ltd. | Cell culture method using bone marrow-like structure, and porous polyimide film for healing bone injury site |
| US10590388B2 (en) | 2015-01-26 | 2020-03-17 | Ube Industries, Ltd. | Cell culture method using bone marrow-like structure, and porous polyimide film for healing bone injury site |
Also Published As
| Publication number | Publication date |
|---|---|
| DE4118201C2 (en) | 2003-03-13 |
| DE4118201A1 (en) | 1992-12-10 |
| JPH03176066A (en) | 1991-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Bessho et al. | A bioabsorbable poly-L-lactide miniplate and screw system for osteosynthesis in oral and maxillofacial surgery | |
| US6203545B1 (en) | Implant for fixing bone fragments after an osteotomy | |
| US5569250A (en) | Method and apparatus for securing adjacent bone portions | |
| ES2264254T3 (en) | BIOABSORBIBLE DEFORMABLE FIXING PLATE. | |
| JP3321182B2 (en) | Surgical fasteners for tissue treatment | |
| US6423062B2 (en) | Bioabsorbable pin for external bone fixation | |
| Hope et al. | Biodegradable pin fixation of elbow fractures in children. A randomised trial | |
| US6503278B1 (en) | Under tissue conditions degradable material and a method for its manufacturing | |
| EP0566255B1 (en) | Perforated metallic panels and strips for internal fixation of bone fractures and for reconstructive surgery | |
| JP3323244B2 (en) | Self-fixating disassembled absorbable screws and plates for internal fixation of fractures and attachment of tendons to bone | |
| Suuronen et al. | Update on bioresorbable plates in maxillofacial surgery | |
| Eppley et al. | Nonmetallic fixation in traumatic midfacial fractures | |
| JP2005507681A (en) | Form-compatible bioabsorbable mesh implant | |
| JP3503045B2 (en) | Shape memory biodegradable absorbent material | |
| JPH09617A (en) | Pin for surgery | |
| JP2004512090A (en) | Non-metallic implant device and method of assembling and securing intraoperatively | |
| JP2007516787A (en) | Surgical absorbable fixation device | |
| EP0815878A3 (en) | High strength internal bone fixation devices and process for forming same | |
| JP5562831B2 (en) | Fixed device | |
| JP3029266B2 (en) | Osteosynthesis material | |
| WO2008085235A2 (en) | Bioabsorbable occlusion device | |
| US5275602A (en) | Bone-joining articles | |
| CN212066847U (en) | Absorbable binding device | |
| CN106880396A (en) | A kind of Fracture internal fixaiion screw of degradable absorption | |
| JP3177848B2 (en) | Osteosynthesis material |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20080204 Year of fee payment: 8 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090204 Year of fee payment: 9 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090204 Year of fee payment: 9 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100204 Year of fee payment: 10 |
|
| EXPY | Cancellation because of completion of term |