JP3191964B2 - Internal fixation type artificial blood vessel and transplantation set including the same - Google Patents
Internal fixation type artificial blood vessel and transplantation set including the sameInfo
- Publication number
- JP3191964B2 JP3191964B2 JP35099591A JP35099591A JP3191964B2 JP 3191964 B2 JP3191964 B2 JP 3191964B2 JP 35099591 A JP35099591 A JP 35099591A JP 35099591 A JP35099591 A JP 35099591A JP 3191964 B2 JP3191964 B2 JP 3191964B2
- Authority
- JP
- Japan
- Prior art keywords
- blood vessel
- artificial blood
- balloon
- cylindrical member
- internally fixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000004204 blood vessel Anatomy 0.000 title claims description 59
- 239000002473 artificial blood Substances 0.000 title claims description 40
- 238000002054 transplantation Methods 0.000 title description 2
- 239000000945 filler Substances 0.000 claims description 10
- 239000007788 liquid Substances 0.000 description 10
- 206010002329 Aneurysm Diseases 0.000 description 6
- 238000002347 injection Methods 0.000 description 6
- 239000007924 injection Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 208000007474 aortic aneurysm Diseases 0.000 description 3
- 239000000178 monomer Substances 0.000 description 3
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 2
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 2
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000004568 cement Substances 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 150000001993 dienes Chemical class 0.000 description 2
- 235000019353 potassium silicate Nutrition 0.000 description 2
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 229920003051 synthetic elastomer Polymers 0.000 description 2
- 239000005061 synthetic rubber Substances 0.000 description 2
- 229920004934 Dacron® Polymers 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 229920000544 Gore-Tex Polymers 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 208000002223 abdominal aortic aneurysm Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000004299 exfoliation Methods 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 description 1
- 210000003090 iliac artery Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Landscapes
- Prostheses (AREA)
Description
【０００１】[0001]
【産業上の利用分野】本発明は、血管の内側に人工血管
を挿入して、前記人工血管を血管に完全に結着するため
の内固定型人工血管およびそれを使用するための移植用
セットに関するものである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an internally fixed artificial blood vessel for inserting an artificial blood vessel inside a blood vessel and completely bonding the artificial blood vessel to the blood vessel, and a transplantation set for using the same. It is about.
【０００２】[0002]
【従来技術】従来、血管と人工血管を結着する手段とし
ては、第一に血管と人工血管を縫合する方法（図１参
照）、第二に端部に硬質円筒部材を有する人工血管を血
管内に挿入し、その上から糸または針金で結束する方法
（図２参照）である。しかし、いずれの方法も人工血管
と縫合あるいは結束しようとする血管周囲を剥離しなけ
ればならない。血管が脆弱であったり、あるいは炎症・
感染を生じている場合には血管壁の剥離がうまく行え
ず、縫合、結束が困難となる場合が多い。2. Description of the Related Art Conventionally, as means for connecting a blood vessel and an artificial blood vessel, first, a method of suturing the blood vessel and the artificial blood vessel (see FIG. 1), and And tying it with a thread or wire from above (see FIG. 2). However, in either method, it is necessary to peel around the blood vessel to be sutured or tied to the artificial blood vessel. Vessels are fragile or inflamed
In the case of infection, the blood vessel wall cannot be successfully detached, and suturing and bundling often become difficult.
【０００３】[0003]
【目的】本発明の目的は、人工血管と結着すべき血管が
多少損傷していても、あるいは多少炎症・感染していて
も簡単に結着することのできる内固定型人工血管および
それを使用した移植用セットを提供する点にある。[Object] An object of the present invention is to provide an internally fixed artificial blood vessel which can be easily attached even if the blood vessel to be connected to the artificial blood vessel is somewhat damaged, or is slightly inflamed or infected, and an object thereof. The point is to provide the transplant set used.
【０００４】[0004]
【構成】本発明の第１は、人工血管本体、その端部に設
けられた硬質円筒部材および前記円筒部材上に設けられ
たバルーンよりなることを特徴とする内固定型人工血管
に関する。本発明の第２は、人工血管本体、その端部お
よび任意個所に設けられた複数の硬質円筒部材および前
記円筒部材上に設けられたバルーンよりなることを特徴
とする内固定型人工血管に関する。本発明の第３は、前
記内固定型人工血管、前記バルーンに充填剤を注入する
ための注入器および前記充填剤よりなる内固定型人工血
管移植用セットに関する。A first aspect of the present invention relates to an internally fixed type artificial blood vessel comprising an artificial blood vessel main body, a rigid cylindrical member provided at an end thereof, and a balloon provided on the cylindrical member. A second aspect of the present invention relates to an internally-fixed artificial blood vessel, which comprises an artificial blood vessel main body, a plurality of hard cylindrical members provided at an end thereof and an arbitrary position, and a balloon provided on the cylindrical member. A third aspect of the present invention relates to the internally fixed type artificial blood vessel, an injector for injecting a filler into the balloon, and a set for implanting an internally fixed type artificial blood vessel including the filler.
【０００５】本発明で使用する人工血管には格別の制限
はなく、テフロン、ダクロン（商品名）、ゴアテックス
（商品名）など現在使用されているいずれの人工血管で
も使用できる。その端部に結合している硬質円筒部材に
ついても格別の制限はなく、現在使用されているいずれ
の円筒部材も使用できる。前記バルーンは、本発明の重
要部材であり、このバルーン内に注入器によって充填剤
が注入されたとき、バルーンが充填剤によって膨張し、
血液が漏れない程度であってかつ血管を破損しない程度
に血管の内壁に圧着する作用をするものである。バルー
ンの前記硬質円筒部材側は任意の手段で固定されている
ことが好ましい。例えば適当な接着剤により接着するこ
とができる。バルーンの構成材料としては、バルーンが
前記膨張に充分耐えるものであればよく、例えば、天然
あるいは合成ゴムなどを使用することができる。合成ゴ
ムとしては、ブタジエン、イソプレンなどのジエン系モ
ノマーの重合または共重合体、ＳＢＲのような前記ジエ
ン系モノマーとスチレンなどのオレフィン系モノマーと
の共重合体、シリコーン系ゴム、ポリウレタンおよびこ
れらのふっ素原子含有ゴムなどを挙げることができる。
とくにこれらの材料と血液が接触したとき、血液の凝固
を発生する恐れのないものがこのましい。前記充填剤と
しては、注入時に液状であり、万が一血液と接触しても
毒性を示さないものであれば、とくに制限はない。たと
えば注入時も使用時も液状のものでもよいし、注入時は
液状であっても使用時はゲル状あるいは固体状のもので
もよい。この場合は液状のときよりゲル状や固体状のと
きの方が体積が減少しないものを選択することが大切で
ある。注入時に液状であるが反応により固体化するもの
としては、Ａ液とＢ液よりなる二液型のものがある。具
体例を挙げると、フィブリングルー（商品名、ベリプラ
スト、ティシールなど）、水ガラス系の溶液型注入剤
（商品名、アデロック１号、サンコーポールＵＳ、セキ
スイＬＧ−３、ＭＧロック１号など）、セメント、水ガ
ラス系の半懸濁型注入剤（商品名、ＳＧＲ−７号、岩水
３号、サンコーポールＬ、ＭＳ−１など）、セメント系
の懸濁型注入剤（商品名、ＭＣ−１号、ストップクリー
ト、デンカＥＳなど）、硬化性合成樹脂とその硬化剤
（エポキシ樹脂とその硬化剤）等を挙げることができ
る。上記の各二液型充填剤に関し、固型化剤を少量にし
て注入すれば、バルーン内の注入剤は固体化せず、長期
間液状またはゲル状でとどまっている。There is no particular limitation on the artificial blood vessel used in the present invention, and any artificial blood vessel currently used such as Teflon, Dacron (trade name), Gore-Tex (trade name) can be used. There is no particular limitation on the rigid cylindrical member connected to the end, and any cylindrical member currently used can be used. The balloon is an important member of the present invention, when the filler is injected by an injector into the balloon, the balloon is inflated by the filler,
It acts to press the inner wall of the blood vessel so that the blood does not leak and the blood vessel is not damaged. It is preferable that the rigid cylindrical member side of the balloon is fixed by any means. For example, they can be bonded with a suitable adhesive. As a constituent material of the balloon, any material can be used as long as the balloon can sufficiently withstand the above-mentioned expansion. For example, natural or synthetic rubber can be used. Examples of the synthetic rubber include a polymer or copolymer of a diene monomer such as butadiene and isoprene, a copolymer of the diene monomer such as SBR and an olefin monomer such as styrene, silicone rubber, polyurethane, and fluorine of these. Atomic rubbers and the like can be mentioned.
Particularly, those materials which do not cause blood coagulation when they come into contact with these materials are preferred. The filler is not particularly limited as long as it is liquid at the time of injection and does not exhibit toxicity even in the event of contact with blood. For example, it may be liquid at the time of injection or use, or may be liquid at the time of injection or gel or solid at the time of use. In this case, it is important to select one that does not decrease in volume when it is in a gel or solid state than when it is in a liquid state. As a liquid which is liquid at the time of injection but solidified by a reaction, there is a two-liquid type composed of liquid A and liquid B. Specific examples include fibrin glue (trade name, Beriplast, Tiseal, etc.), water-glass-based solution-type injectables (trade name, Adeloc 1, Sankopol US, Sekisui LG-3, MG Rock 1, etc.), Cement, water glass type semi-suspension type injection agent (trade name, SGR-7, Iwamizu 3, Suncorpor L, MS-1, etc.), cement type suspension type injection agent (trade name, MC-1) , Stop cleats, Denka ES, etc.), curable synthetic resins and their curing agents (epoxy resins and their curing agents), and the like. With respect to each of the above two-pack fillers, if the solidifying agent is injected in a small amount, the filler in the balloon does not solidify and remains in a liquid or gel state for a long time.
【０００６】本発明を図面を参照して説明する。図３
は、本発明の１例を示す内固定型人工血管を動脈瘤部分
をもつ血管内に固定した状態を表わしている。１は人工
血管本体、２は硬質円筒部材、３はバルーンであり、４
は血管壁、５は血管の動脈瘤部分である。バルーン内に
充填剤を充填する態様としては、図４のようなものがあ
る。血管壁４の端部に本発明の内固定型人工血管の端部
を挿入し、ついで硬質円筒部材２の周面に設けられたバ
ルーン３と血管壁４の間には圧力計７の計測部を挿入
し、２つの注入器６を用いて２液型充填剤を圧力計の目
盛に注意しつつバルーン３内に注入する。図５は、枝分
かれしている人工血管１の各端部にそれぞれ硬質円筒部
材２およびバルーン３よりなる本発明のもう１つのタイ
プを示す。腹部大動脈瘤が左右の総腸骨動脈におよんで
いる場合、このようなＹ字型の人工血管が有効となる。
図６は、第２の本発明の一具体例を示すものであり、人
工血管本体両端部の他に多数のバルーン３付き硬質円筒
部材２をもつ内固定型人工血管である。上行大動脈瘤、
下行大動脈瘤など、太くて短い範囲の動脈瘤の際、手術
後人工血管が移動しにくいように、両端部のバルーンを
血管外から補足固定するとより安全な手術が可能とな
る。図７は、本発明の他の使用態様を示すものであり、
血管４と内固定型人工血管のバルーン３付き硬質円筒部
材２部分を糸または針金で軽くしばり、両者の結着を一
層強固なものとすることができる。The present invention will be described with reference to the drawings. FIG.
Shows a state in which an internally fixed artificial blood vessel showing one example of the present invention is fixed in a blood vessel having an aneurysm portion. 1 is an artificial blood vessel main body, 2 is a rigid cylindrical member, 3 is a balloon, 4
Is a blood vessel wall, and 5 is an aneurysm portion of a blood vessel. FIG. 4 shows an embodiment of filling the filler in the balloon. The end of the internally fixed type artificial blood vessel of the present invention is inserted into the end of the blood vessel wall 4, and the measuring section of the pressure gauge 7 is provided between the balloon 3 provided on the peripheral surface of the rigid cylindrical member 2 and the blood vessel wall 4. Is inserted into the balloon 3 using two injectors 6 while paying attention to the scale of the pressure gauge. FIG. 5 shows another type of the invention comprising a rigid cylindrical member 2 and a balloon 3 at each end of a branched artificial blood vessel 1, respectively. When the abdominal aortic aneurysm extends to the left and right common iliac arteries, such a Y-shaped artificial blood vessel is effective.
FIG. 6 shows a specific example of the second present invention, which is an internally fixed artificial blood vessel having a number of rigid cylindrical members 2 with balloons 3 in addition to both ends of the artificial blood vessel main body. Ascending aortic aneurysm,
In the case of an aneurysm of a large and short range such as a descending aortic aneurysm, safer surgery is possible by supplementing and fixing balloons at both ends from outside the blood vessel so that the artificial blood vessel is difficult to move after the operation. FIG. 7 shows another use mode of the present invention.
The blood vessel 4 and the portion of the rigid cylindrical member 2 with the balloon 3 of the internally fixed artificial blood vessel can be lightly tightened with a thread or a wire, so that the binding between the two can be further strengthened.
【０００７】[0007]
【効果】本発明の内固定型人工血管を使用すれば、動脈
瘤周辺に癒着が強く、剥離が困難な時でも、血管の切除
部分ができるかぎり少ない手術が可能であり、また、手
術を短時間で終わらせることができる。[Effect] By using the internally fixed type artificial blood vessel of the present invention, even when the adhesion around the aneurysm is strong and the exfoliation is difficult, it is possible to perform an operation with as little resection of the blood vessel as possible and to shorten the operation. It can be done in time.
【図１】従来の人工血管を用いた従来型処置方法を示す
概略図である。FIG. 1 is a schematic view showing a conventional treatment method using a conventional artificial blood vessel.
【図２】従来の人工血管を用いた他の従来型処置方法を
示す概略図である。FIG. 2 is a schematic view showing another conventional treatment method using a conventional artificial blood vessel.
【図３】動脈瘤部分に本発明の１具体的な内固定型人工
血管を挿入した手術結果の概略図である。FIG. 3 is a schematic view of the result of an operation in which one specific internal fixation type artificial blood vessel of the present invention is inserted into an aneurysm portion.
【図４】本発明の内固定型人工血管を用いた手術方法の
概略図である。FIG. 4 is a schematic view of a surgical method using the internally fixed type artificial blood vessel of the present invention.
【図５】本発明の他の具体的な内固定型人工血管の概略
図を示す。FIG. 5 shows a schematic diagram of another specific internally fixed type artificial blood vessel of the present invention.
【図６】本発明のもう１つの他の具体的な内固定型人工
血管の概略図を示す。FIG. 6 shows a schematic view of another another specific internal fixation vascular prosthesis of the present invention.
【図７】本発明の内固定型人工血管を用いたもう１つの
手術方法の概略図である。FIG. 7 is a schematic view of another surgical method using the internally fixed type artificial blood vessel of the present invention.
１ 人工血管本体 ２ 硬質円筒部材 ３ バルーン ４ 血管壁 ５ 血管の動脈瘤部分 ６ 注入器 ７ 圧力計 ８ 糸または針金 DESCRIPTION OF SYMBOLS 1 Artificial blood vessel main body 2 Hard cylindrical member 3 Balloon 4 Blood vessel wall 5 Aneurysm part of blood vessel 6 Injector 7 Pressure gauge 8 Thread or wire
Claims (3)
質円筒部材および前記円筒部材上に設けられたバルーン
よりなることを特徴とする内固定型人工血管。1. An internally fixed artificial blood vessel comprising an artificial blood vessel main body, a rigid cylindrical member provided at an end thereof, and a balloon provided on the cylindrical member.
に設けられた硬質円筒部材および前記円筒部材上に設け
られたバルーンよりなることを特徴とする内固定型人工
血管。2. An internally fixed artificial blood vessel comprising an artificial blood vessel main body, a rigid cylindrical member provided at an end thereof and an arbitrary position, and a balloon provided on the cylindrical member.
型人工血管、前記バルーンに充填剤を注入するための注
入器および前記充填剤よりなる内固定型人工血管移植用
セット。3. An internally fixed artificial blood vessel transplant set comprising the internally fixed artificial blood vessel according to claim 1 and / or 2, an injector for injecting a filler into the balloon, and the filler.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35099591A JP3191964B2 (en) | 1991-12-11 | 1991-12-11 | Internal fixation type artificial blood vessel and transplantation set including the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35099591A JP3191964B2 (en) | 1991-12-11 | 1991-12-11 | Internal fixation type artificial blood vessel and transplantation set including the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05161665A JPH05161665A (en) | 1993-06-29 |
| JP3191964B2 true JP3191964B2 (en) | 2001-07-23 |
Family
ID=18414325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP35099591A Expired - Fee Related JP3191964B2 (en) | 1991-12-11 | 1991-12-11 | Internal fixation type artificial blood vessel and transplantation set including the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3191964B2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6395019B2 (en) | 1998-02-09 | 2002-05-28 | Trivascular, Inc. | Endovascular graft |
| EP1982658A1 (en) * | 2007-04-16 | 2008-10-22 | Corlife GbR | Vessel connector and kit with applicator for surgery |
| AU2008308474B2 (en) | 2007-10-04 | 2014-07-24 | Trivascular, Inc. | Modular vascular graft for low profile percutaneous delivery |
-
1991
- 1991-12-11 JP JP35099591A patent/JP3191964B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05161665A (en) | 1993-06-29 |
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