JP3538255B2 - Package of prefilled syringe and piston rod - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a prefilled syringe package which is pre-filled with a chemical solution.

[0002]

2. Description of the Related Art Conventionally, the following packages are generally known as prefilled syringe packages. (1) A shrink package in which a prefilled syringe and a piston rod are wrapped together with a shrink film, and the prefilled syringe and the piston rod are fixed by heat shrinkage of the shrink. (2) The prefilled syringe and the piston rod are housed together in one small resin pouch.
Pouch packaging. (3) A blister package in which a prefilled syringe and a piston rod are housed together in one recess formed in a plastic sheet, and a film is attached to an opening of the recess.

[0003]

For example, when a prefilled syringe filled with a contrast medium is used in a hospital, the contrast medium is heated to about body temperature by a microwave oven before use. However, in each of the packages (1) to (3), since the prefilled syringe and the piston rod are housed together, when heating the contrast agent, even the piston rod that does not require heating is heated together. You.
This causes a problem that the piston rod is deformed by being heated. Further, wasteful energy is wasted for heating the piston rod. And the above (1)-
The package of (3) has a large volume because both the prefilled syringe and the piston rod are housed together,
Many packages do not fit in the microwave. Therefore, the packages (1) to (3) cannot heat many prefilled syringes at one time.

On the other hand, in order to heat many pre-filled syringes at once, if the package is opened and only the pre-filled syringe is put in a microwave oven, another problem such as impairing the sterility of the pre-filled syringe is lost. Occurs.

It is an object of the present invention to provide a package in which a prefilled syringe and a piston rod are individually stored.

[0006]

In order to solve the above-mentioned problems, in the present invention, a chemical is filled in an outer cylinder, and a gasket is inserted into an opening formed at a rear end of the outer cylinder. A prefilled syringe with a cap attached to a nozzle formed at the tip of the outer cylinder is housed in a concave portion formed in a plastic sheet, and a film is attached to an opening of the concave portion. Body, a piston rod attached to the gasket of the prefilled syringe is housed in a recess formed in the plastic sheet, and a film is applied to the opening of the recess, the piston rod packaging body,
A prefilled syringe and piston rod wrapper is provided that is releasably connected via a plastic sheet and / or a film of each other.

[0007] In this package, preferably, the above-flops
Refilled syringe package and piston rod
A perforation is provided in the part connecting the package
I have. In addition, the prefilled syringe package and
At the part connecting the piston rod package and
The thickness of the plastic sheet to be cut is thinner than other parts
Has been established.

[0008]

The package of the present invention can separate the package of the prefilled syringe and the package of the piston rod from each other when the contrast medium is heated in a hospital. Therefore, the package of the present invention can be heated by placing only the package of the prefilled syringe in a microwave oven.

[0009]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Embodiments of the present invention will be described below with reference to the drawings. FIG. 1 is a sectional view of a prefilled syringe 1, and FIG. 2 is a side view of a piston rod 2. As shown in FIG. 1, a gasket 5 made of an elastic material such as rubber is inserted into an opening 4 formed at a rear end of a cylindrical outer cylinder 3. Further, a cap 7 made of an elastic material such as rubber is attached to a nozzle 6 formed at the tip of the outer cylinder 3. The outer cylinder 3 is made of, for example, a transparent material such as glass or plastic. Inside the outer cylinder 3,
The liquid medicine 8 has already been filled. The peripheral surface of the gasket 5 that is in contact with the inner surface of the outer cylinder 3 is coated with a lubricant such as silicon. A screw hole 10 is provided in the center of the rear surface of the gasket 5. Such a prefilled syringe 1 is
According to the “container / syringe” of Japanese Utility Model Laid-Open No. 2-116457 and the “container / syringe” of Japanese Utility Model Application No. 3-9753,
It is known.

[0010] As shown in FIG.
Is a rod 11 having a thickness that can be inserted into the outer cylinder 3.
Is provided. At the tip of the rod 11, a screw portion 12 that can be screwed into a screw hole 10 provided on the rear surface of the gasket 5 is formed. A flange 13 is formed at the rear end of the rod 11. The piston rod 2 is made of, for example, vinyl chloride,
It is made of a material such as plastic.

FIG. 3 is a plan view of the package 20 according to the embodiment of the present invention, and FIG. 4 is a sectional view taken along the line AA in FIG.
The package 20 includes a package 22 of the prefilled syringe 1 and a package 23 of the piston rod 2. The package 22 of the prefilled syringe 1 and the package 23 of the piston rod 2 are connected at a connection portion 25.

The package 22 of the prefilled syringe 1 and the package 23 of the piston rod 2 are both blister packages. In the package 22 of the prefilled syringe 1, the prefilled syringe 1 is housed in the recess 27 formed in the plastic sheet 26, and the film 28 is attached to the opening of the recess 27. In the package 23 of the piston rod 2, the piston rod 2 is housed in the recess 31 formed in the plastic sheet 30, and the recess 31 is formed.
The film 32 is adhered to the opening of. The films 28 and 32 are bonded or welded to the upper surfaces of the plastic sheets 26 and 30.

In this embodiment, the plastic sheet 26
The plastic sheet 30 is formed of a single plastic sheet including the connecting portion 25, and has a configuration in which the concave portions 27 and the concave portions 31 are formed on both sides of the connecting portion 25 by heat molding. Further, the film 28 and the film 32 are also formed of a single film including the connecting portion 25, and the concave portions 27 and 31 are integrally covered with the single film. Film 28 and film 32
It consists of paper, paperboard, plastic film, aluminum foil, etc. In addition, the package 2 of the prefilled syringe 1
2 and the package 23 of the piston rod 2 are connected separately to each other (packages 2 manufactured separately from each other).
2 and the package 23) may be joined at the connection portion 25 by, for example, bonding, welding, or the like.

FIG. 5 is an enlarged view of the connecting portion 25 connecting the plastic sheets 26 and 30 and the films 28 and 32. The connecting portion 25 is provided with, for example, a perforation. The perforations allow the plastic sheet 26 and the plastic sheet 30 to be separated from the film 28 and the film 32 at the connecting portion 25. Instead of perforations, for example, a configuration in which the thickness of the plastic sheet in the connecting portion 25 is formed thinner than other portions is also employed. By providing the perforations and the like, the plastic sheet 26 and the plastic sheet 30 and the film 28 and the film 32
At 5 it is possible to bend.

As shown in FIG. 6, the package 2 of this embodiment
Reference numeral 0 denotes a package 22 of the prefilled syringe 1 and a package 23 of the piston rod 2 which are bent at the connecting portion 25.
Can be superimposed. FIG. 7 shows a package 22 of the prefilled syringe 1 and a package 23 of the piston rod 2.
2 shows a state in which a plurality of packages 20 are stacked without overlapping. On the other hand, FIG. 8 shows a state in which a plurality of packages 20 in which the package 22 of the prefilled syringe 1 and the package 23 of the piston rod 2 are bent at the connecting portion 25 are stacked. As shown in FIG. 8, by stacking the packages 20 bent at the connecting portions 25, there is an advantage that a large number of packages 20 can be stored densely with a small volume.

The package 20 of this embodiment has a connecting portion 25
In the above, the package 22 of the prefilled syringe 1 and the package 23 of the piston rod 2 can be separated from each other. Therefore, when heating the contrast agent, for example, the package 20 of this embodiment is cut into two at the connecting portion 25,
Only the package 22 of the prefilled syringe 1 can be placed in a microwave oven and heated. As a result, a larger number of prefilled syringes 1 enter the microwave oven, and a large number of prefilled syringes 1 can be heat-treated at one time.

[0017]

According to the present invention, since a large number of prefilled syringes are housed in the microwave oven at a time, the processing time required for heating is shortened as compared with the prior art. In addition, the prefilled syringe package and the piston rod package are packaged until immediately before use, so that cleanliness is maintained.

[Brief description of the drawings]

FIG. 1 is a cross-sectional view of a prefilled syringe.

FIG. 2 is a side view of a piston rod.

FIG. 3 is a plan view of a package according to an embodiment of the present invention.

FIG. 4 is a sectional view taken along the line AA in FIG. 3;

FIG. 5 is an enlarged view of a connecting portion.

FIG. 6 is a view showing a state in which a package of a prefilled syringe and a package of a piston rod are overlapped by being bent at a connecting portion.

FIG. 7 is a view showing a state where a plurality of packages are stacked.

FIG. 8 is a view showing a state in which a plurality of packages folded at the connecting portion are stacked;

[Explanation of symbols]

1 prefilled syringe 2 Piston rod 20 Package of prefilled syringe and piston rod 22 Package of prefilled syringe 23 Package of piston rod 25 Connecting part

──────────────────────────────────────────────────続 き Continuation of front page (56) References JP-A-51-32307 (JP, A) JP-A 1-279031 (JP, A) JP-A 5-178385 (JP, A) JP-A 3- 240664 (JP, A) Hikaru 4-11038 (JP, U) (58) Fields investigated (Int. Cl. ⁷ , DB name) A61M 5/178 A61J 1/14

Claims (3)

(57) [Claims] 1. A prefilled structure in which a chemical solution is filled in an outer cylinder, a gasket is inserted into an opening formed at a rear end of the outer cylinder, and a cap is attached to a nozzle formed at a tip of the outer cylinder. A syringe is housed in a recess formed in a plastic sheet, and a film is attached to an opening of the recess.A package of a prefilled syringe, and a piston rod attached to a gasket of the prefilled syringe are made of plastic. housed in a recess formed in a sheet, a film in the opening of the concave portion is adhered, packaging of the piston rod and is rotatably connected disconnected via the plastic sheet and / or another of the film of each other , Prefilled syringe and piston rod packaging. 2. A package of the prefilled syringe,
At the part connecting the piston rod package and
The prefill according to claim 1, wherein a perforation is provided.
A package of a syringe and a piston rod. 3. A package of the prefilled syringe,
At the part connecting the piston rod package and
The thickness of the plastic sheet to be cut is thinner than other parts
The pre-filled syringe according to claim 1, which is formed.
And piston rod packaging.