JP3565320B2 - Oil-in-water emulsion composition containing inorganic salt - Google Patents
Oil-in-water emulsion composition containing inorganic salt Download PDFInfo
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- JP3565320B2 JP3565320B2 JP21116299A JP21116299A JP3565320B2 JP 3565320 B2 JP3565320 B2 JP 3565320B2 JP 21116299 A JP21116299 A JP 21116299A JP 21116299 A JP21116299 A JP 21116299A JP 3565320 B2 JP3565320 B2 JP 3565320B2
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- Prior art keywords
- oil
- water emulsion
- emulsion composition
- inorganic salt
- composition containing
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- 239000000203 mixture Substances 0.000 title claims description 20
- 239000007764 o/w emulsion Substances 0.000 title claims description 17
- 229910017053 inorganic salt Inorganic materials 0.000 title description 12
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 10
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 6
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 6
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 5
- 241001131796 Botaurus stellaris Species 0.000 claims description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 3
- 239000001110 calcium chloride Substances 0.000 claims description 3
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 3
- 229910001629 magnesium chloride Inorganic materials 0.000 claims description 3
- 235000011147 magnesium chloride Nutrition 0.000 claims description 3
- 239000001103 potassium chloride Substances 0.000 claims description 3
- 235000011164 potassium chloride Nutrition 0.000 claims description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 3
- 235000011152 sodium sulphate Nutrition 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000008346 aqueous phase Substances 0.000 description 7
- 239000002537 cosmetic Substances 0.000 description 7
- 239000003921 oil Substances 0.000 description 7
- 238000000926 separation method Methods 0.000 description 7
- 235000002639 sodium chloride Nutrition 0.000 description 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 239000012071 phase Substances 0.000 description 6
- 150000005846 sugar alcohols Polymers 0.000 description 5
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 238000004220 aggregation Methods 0.000 description 4
- 230000002776 aggregation Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 229920002683 Glycosaminoglycan Polymers 0.000 description 3
- 238000004945 emulsification Methods 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 239000013535 sea water Substances 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- 229940058015 1,3-butylene glycol Drugs 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- 239000006096 absorbing agent Substances 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 235000019437 butane-1,3-diol Nutrition 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 239000003906 humectant Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- -1 fatty acid ester Chemical class 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- OTCKOJUMXQWKQG-UHFFFAOYSA-L magnesium bromide Chemical compound [Mg+2].[Br-].[Br-] OTCKOJUMXQWKQG-UHFFFAOYSA-L 0.000 description 1
- 229910001623 magnesium bromide Inorganic materials 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 239000000845 maltitol Substances 0.000 description 1
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
- 235000010449 maltitol Nutrition 0.000 description 1
- 229940035436 maltitol Drugs 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- WBHHMMIMDMUBKC-QJWNTBNXSA-M ricinoleate Chemical compound CCCCCC[C@@H](O)C\C=C/CCCCCCCC([O-])=O WBHHMMIMDMUBKC-QJWNTBNXSA-M 0.000 description 1
- 229940066675 ricinoleate Drugs 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Colloid Chemistry (AREA)
Description
【０００１】
【発明の属する技術分野】
この発明は、無機塩を含有しているにもかかわらず、安定性の良好な水中油型乳化組成物に関する。
【０００２】
【従来の技術】
無機塩は人体の代謝を活性化する作用を有することから、無機塩を化粧料に配合することが古くから提案されている。例えば、ムコ多糖類，ビタミンＥ類と併用した化粧料（特開昭６２−２０９００９）、ムコ多糖類，リン脂質と併用した化粧料（特開昭６２−２０９０１０）等が開示されている。
【０００３】
しかしながら、無機塩を含有する水中油型乳化組成物は、乳化安定性が悪く、経時での離水など安定性の悪化が認められた。そこで、無機塩を含有する水中油型エマルションにおいて、その安定性を高めるために、ポリグリセリン縮合リシノレイン酸エステルにクエン酸モノグリセライドやコハク酸モノグリセライドを併用した乳化剤を配合する（特開平１−２１００２９），ポリグリセリン脂肪酸エステル組成物を乳化剤として配合する（特開平８−２１７７２４），ノニオン界面活性剤と常温で液状の多価アルコール多価脂肪酸エステルを配合する（特開平１１−３５４４７）等の技術が開示されているが、化粧料として長期保存に耐えうる乳化安定性の良好な無機塩含有水中油型乳化組成物は得られていない。
【０００４】
【発明が解決しようとする課題】
本発明の目的は、乳化安定性の良好な無機塩含有水中油型乳化組成物を提供することである。
【０００５】
【課題を解決するための手段】
本発明者は、上記課題を解決するために研究を重ねた結果、無機塩を含有する水中油型乳化組成物において、１，２−ペンタンジオールを配合することにより、乳化安定性が飛躍的に向上することを見いだし、本発明を完成するに至った。
【０００６】
【発明の実施の形態】
本発明の実施の形態を説明する。
【０００７】
本発明において使用する１，２−ペンタンジオールは、下記の式（１）で表される構造をとる。
ＣＨ３（ＣＨ２）２ＣＨ（ＯＨ）ＣＨ２ＯＨ …式（１）
この１，２−ペンタンジオールについては、通常は保湿成分として配合される他、防腐成分としての応用（熱測定，２６（１），２−８，（１９９９））、マイクロエマルションにおける共溶媒としての応用（Ｌａｎｇｍｕｉｒ，１１（１１），４１８５−４１８７，（１９９５））等が検討されている。
【０００８】
１，２−ペンタンジオールは、通常公知の方法を用いて製造したものを本発明の水中油型乳化組成物に配合することができる。また、ドラゴコ，デグッサ，ストラトマンズなどより製品化されている市販品を使用することもできる。
【０００９】
１，２−ペンタンジオールの本発明の水中油型乳化組成物への配合量は、特に制限されるものではないが、乳化安定性を向上させるためには、乳化組成物全量に対して、０．１重量％〜２０．０重量％の割合で配合することが好ましい。
【００１０】
本発明で用いられる無機塩は特に限定されないが、塩化ナトリウム，塩化マグネシウム，硫酸ナトリウム，塩化カリウム，臭化カリウム，塩化カルシウム等が例示される。これらの無機塩は、合成品を単品で若しくは組み合わせて配合するほか、海水由来のニガリ，海水乾燥末などの天然物を単独若しくは組み合わせて用いてもかまわない。なおニガリは、海水を濃縮し塩化ナトリウムを析出させた後に残る残塩で、塩化ナトリウムの他、塩化カリウム，硫酸マグネシウム，臭化マグネシウム，塩化マグネシウム，硫酸ナトリウム，臭化カリウム，塩化カルシウムなどの混合物である。
【００１１】
これら無機塩の水中油型乳化組成物への配合量は、０．０１〜１０．０重量％が好ましい。また無機塩は水相成分に溶解した状態で，或いは粒状等結晶状態の何れで配合してもよい。
【００１２】
本発明の水中油型乳化組成物には上記成分以外にも、乳化剤、グリセリン，１，３−ブチレングリコール等の多価アルコール、アミノ酸，ムコ多糖類といった保湿剤、紫外線吸収剤、酸化防止剤、殺菌剤、抗炎症剤、防腐剤、香料など一般的に化粧料に用いられる添加成分を配合することができる。
【００１３】
本発明においては、上記した無機塩と１，２−ペンタンジオールを併用することにより、安定性の良好な水中油型乳化組成物を提供する。本発明における水中油型乳化組成物は、乳液状若しくはクリーム状の膏剤若しくは化粧料の形で用いられる。さらに、本発明に係る水中油型乳化組成物においては、本発明の特徴を損なわない範囲で、各種油分，界面活性剤，低級一価アルコール，保湿剤，多価アルコール，細胞賦活剤，抗酸化剤，美白剤，紫外線吸収剤，防菌防黴剤，顔料，色素類，香料等、一般的な化粧料，医薬品配合成分を加えることができる。
【００１４】
【実施例】
さらに実施例により、本発明の特徴について詳細に説明する。
【００１５】
【００１６】
【００１７】
【００１８】
【００１９】
本発明の実施例について、安定性の検討を行った。安定性は、４０℃恒温槽にて１ヶ月保存後の状態を観察し、「○：離水や凝集が認められない」，「△：離水或いは凝集が僅かに認められる」，「×：離水或いは凝集が明確に認められる」の３段階で評価した。同時に、１，２−ペンタンジオールを実施例１ではグリセリンに、実施例２では精製水に、実施例３では１，３−ブチレングリコールに、実施例４ではマルチトールに代替して水中油型乳化組成物を調製し，それぞれ比較例１〜比較例４とし、安定性評価を行った。安定性評価結果を表１に示す。
【００２０】
【表１】
表１より明らかなように、本発明の実施例は乳化安定性が良好で、離水や分離は全く認められなかった。しかしながら、１，２−ペンタンジオールを他の多価アルコールや精製水に代替した比較例においては、すべて明確な離水が認められた。
【００２２】
【発明の効果】
以上詳述したように、本発明により無機塩を含有しているにもかかわらず、安定性の良好な水中油型乳化組成物を得ることができた。[0001]
TECHNICAL FIELD OF THE INVENTION
TECHNICAL FIELD The present invention relates to an oil-in-water emulsion composition having good stability despite containing an inorganic salt.
[0002]
[Prior art]
Since inorganic salts have the effect of activating the metabolism of the human body, it has long been proposed to add inorganic salts to cosmetics. For example, cosmetics used in combination with mucopolysaccharide and vitamin E (Japanese Patent Application Laid-Open No. 62-20909), cosmetics used in combination with mucopolysaccharide and phospholipid (Japanese Patent Application Laid-Open No. 62-209010) and the like are disclosed.
[0003]
However, the oil-in-water emulsion composition containing an inorganic salt had poor emulsification stability, and deterioration in stability such as water separation over time was observed. Therefore, in an oil-in-water emulsion containing an inorganic salt, an emulsifier in which polyglycerin condensed ricinoleate is used in combination with citric acid monoglyceride or succinic acid monoglyceride is incorporated in order to enhance the stability (Japanese Patent Laid-Open No. 1-20029). Techniques such as compounding a polyglycerin fatty acid ester composition as an emulsifier (JP-A-8-217724) and compounding a nonionic surfactant with a polyhydric alcohol ester of a polyhydric alcohol liquid at ordinary temperature (JP-A-11-35447) are disclosed. However, no inorganic salt-containing oil-in-water emulsion composition having good emulsification stability that can withstand long-term storage as a cosmetic has not been obtained.
[0004]
[Problems to be solved by the invention]
An object of the present invention is to provide an inorganic salt-containing oil-in-water emulsion composition having good emulsion stability.
[0005]
[Means for Solving the Problems]
The present inventor has conducted repeated studies to solve the above-mentioned problems, and as a result, by blending 1,2-pentanediol in an oil-in-water emulsion composition containing an inorganic salt, the emulsion stability is dramatically improved. The inventors have found that the present invention is improved, and have completed the present invention.
[0006]
BEST MODE FOR CARRYING OUT THE INVENTION
An embodiment of the present invention will be described.
[0007]
The 1,2-pentanediol used in the present invention has a structure represented by the following formula (1).
CH 3 (CH 2 ) 2 CH (OH) CH 2 OH Formula (1)
This 1,2-pentanediol is usually blended as a moisturizing component, applied as a preservative component (thermal measurement, 26 (1), 2-8, (1999)), and used as a co-solvent in a microemulsion. Applications (Langmuir, 11 (11), 4185-4187, (1995)) and the like are being studied.
[0008]
As the 1,2-pentanediol, one produced by a generally known method can be blended with the oil-in-water emulsion composition of the present invention. Further, commercially available products manufactured by Dragoco, Degussa, Stratmandu and the like can also be used.
[0009]
The amount of 1,2-pentanediol added to the oil-in-water emulsified composition of the present invention is not particularly limited, but in order to improve the emulsification stability, 0 to the total amount of the emulsified composition. It is preferable to mix at a ratio of 0.1 to 20.0% by weight.
[0010]
The inorganic salt used in the present invention is not particularly limited, and examples thereof include sodium chloride, magnesium chloride, sodium sulfate, potassium chloride, potassium bromide, calcium chloride and the like. These inorganic salts may be used alone or in combination with a synthetic product alone or in combination with natural products such as seawater-derived bittern and dried seawater. Bittern is a residual salt remaining after concentrating seawater and precipitating sodium chloride. In addition to sodium chloride, a mixture of potassium chloride, magnesium sulfate, magnesium bromide, magnesium chloride, sodium sulfate, potassium bromide, calcium chloride, etc. It is.
[0011]
The amount of the inorganic salt to be added to the oil-in-water emulsion composition is preferably 0.01 to 10.0% by weight. Further, the inorganic salt may be blended in a state of being dissolved in the aqueous phase component or in a state such as a granular state.
[0012]
In addition to the above components, the oil-in-water emulsion composition of the present invention may further contain emulsifiers, polyhydric alcohols such as glycerin and 1,3-butylene glycol, humectants such as amino acids and mucopolysaccharides, ultraviolet absorbers, antioxidants, Additives generally used in cosmetics, such as bactericides, anti-inflammatory agents, preservatives, and fragrances, can be blended.
[0013]
In the present invention, an oil-in-water emulsion composition having good stability is provided by using the above-mentioned inorganic salt and 1,2-pentanediol in combination. The oil-in-water emulsion composition of the present invention is used in the form of a milky or creamy plaster or a cosmetic. Furthermore, in the oil-in-water emulsion composition according to the present invention, various oils, surfactants, lower monohydric alcohols, humectants, polyhydric alcohols, cell activators, antioxidants, as long as the characteristics of the present invention are not impaired. Common cosmetics and pharmaceutical ingredients such as agents, whitening agents, ultraviolet absorbers, antibacterial and fungicides, pigments, pigments, and fragrances can be added.
[0014]
【Example】
Further, the features of the present invention will be described in detail with reference to examples.
[0015]
[0016]
[0017]
[0018]
[0019]
The stability of the examples of the present invention was examined. The stability was determined by observing the condition after storage in a constant temperature bath at 40 ° C. for one month, and “「: no water separation or aggregation was observed ”,“ △: slight water separation or aggregation was observed ”,“ ×: water separation or aggregation ” Aggregation is clearly observed ". At the same time, 1,2-pentanediol was replaced with glycerin in Example 1, purified water in Example 2, 1,3-butylene glycol in Example 3, and oil-in-water emulsion instead of maltitol in Example 4. Compositions were prepared and Comparative Examples 1 to 4 were evaluated for stability. Table 1 shows the results of the stability evaluation.
[0020]
[Table 1]
As is clear from Table 1, the examples of the present invention had good emulsion stability, and did not show any water separation or separation. However, in Comparative Examples in which 1,2-pentanediol was replaced with another polyhydric alcohol or purified water, clear water separation was all observed.
[0022]
【The invention's effect】
As described in detail above, an oil-in-water emulsion composition having good stability was obtained according to the present invention despite containing an inorganic salt.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21116299A JP3565320B2 (en) | 1999-07-26 | 1999-07-26 | Oil-in-water emulsion composition containing inorganic salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21116299A JP3565320B2 (en) | 1999-07-26 | 1999-07-26 | Oil-in-water emulsion composition containing inorganic salt |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001039826A JP2001039826A (en) | 2001-02-13 |
| JP3565320B2 true JP3565320B2 (en) | 2004-09-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP21116299A Expired - Fee Related JP3565320B2 (en) | 1999-07-26 | 1999-07-26 | Oil-in-water emulsion composition containing inorganic salt |
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| Country | Link |
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| JP (1) | JP3565320B2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001039814A (en) * | 1999-07-27 | 2001-02-13 | Pola Chem Ind Inc | Powder-containing cosmetic |
| JP2003081761A (en) * | 2001-06-27 | 2003-03-19 | Mandom Corp | Emulsified composition |
| JP6008686B2 (en) * | 2012-10-16 | 2016-10-19 | 伯東株式会社 | Antifoaming agent and method for producing the same |
| JP2020128345A (en) * | 2019-02-07 | 2020-08-27 | 株式会社マンダム | Oil-in-water emulsion composition |
| JP7339391B1 (en) | 2022-04-22 | 2023-09-05 | 株式会社コスモビューティー | Oily particle dispersion composition and method for producing the same |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3657395B2 (en) * | 1996-05-27 | 2005-06-08 | 株式会社資生堂 | Composition for external use |
| JP3230579B2 (en) * | 1999-06-01 | 2001-11-19 | 株式会社ファンケル | Cosmetics |
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