JP3732243B2 - Pouch - Google Patents

Description

[0001]
[Industrial application fields]
The present invention relates to a pouch for packaging a semi-solid or gel medicine.
[0002]
[Prior art]
Currently, medicines are taken and drunk in the form of tablets, liquids, powders, solids and the like. Each of them is individually packaged for a single dose or stored in a container for several times before being administered to a patient.
As shown in FIG. 3, there are four-side seals, three-side seals, stick wraps, PTPs, etc. as the packaging of the medicines to be taken. B) Three-way seals, (C) stick packaging, etc. are mainly packaged with powder and granules, and (D) PTP is a tablet packaging method.
These packagings have also been improved for easy opening, but even as healthy people become older, the strength of their fingers weakens, so that the ease of taking out the drugs in these packaging methods is also satisfactory. The situation is not.
Drugs are generally difficult to swallow, and for the drugs themselves, consideration is given to easy use of bitter drugs in sugar-coated tablets or capsules. However, in an aging society, a form of a medicine that is easier to take is desired, and various ideas have been made. The elderly have a problem that it is difficult to take powder and solid medicine, and the dosage form that is easy to take is gel. If it is a gel-like agent, it is easy to take with the suction force of suction from the opening.
In the case of a gel-like medicine, it is necessary to take measures against bacterial contamination and spoilage due to the presence of water contained therein. That is, it is possible to use boil sterilization or retort sterilization techniques frequently used in aseptic packaging or food packaging, and to make individual packaging for each unit of dosage.
On the other hand, as packaging materials and packaging forms suitable for these conditions, cans, bottles, plastic molded products, etc. are conceivable, but from the standpoint of elderly patients, all of them are packages that are difficult to open. The price is expensive for individual packaging.
The most promising possibility is a flexible package, i.e. a pouch, and the selection of the material and pasting (composite filming) and sealing technology will provide a package that is resistant to retort sterilization. As can be imagined from the above, in the pouch in the conventional packaging form as shown in FIGS. 3 (A), (B), (C), the gel body is cut halfway when the patient takes it, and the inside of the packaging bag May remain.
[0003]
[Problems to be solved by the invention]
A conventional medicine dosage form is provided in a semi-solid or gel form to provide fluidity, and a packaging form that is easy to take for general patients and especially elderly patients who will increase in the future is provided. In the gel medicine, the medicine itself is easy to drink (easy to take), but its packaging is a problem. If it is in gel form, the package will be opened and if you try to take it, if it remains in the bag without coming out in its entirety, the medicinal effect will not be fully demonstrated as initially intended, and even if you take it, it seems that the disease will recover There is a risk of not.
Therefore, it is desirable to have a package that can be easily opened and that the whole amount can be easily put into the mouth when inhaled.
[0004]
[Means for Solving the Problems]
So, as a solution to this problem, it was conventionally opened and taken from that side, but the other side of the bag was opened to the extent that the contents would not spill out, and vents were provided so that the patient could take it. It was found that the entire contents were smoothly discharged with the help of the atmospheric pressure by sucking in, and the packaging of the object of the present invention was obtained by providing the packaging, particularly the seal shape and another opening. The pouch looks like this: That is, in the packaging arrangement of deformation sealing of the four-way seal packaging contents as a "final gel, by heat sealing pattern toward the one inside the pouch on the other, the filling portion of the contents of large area, small In order to communicate with the non-sealed portion of the area through a narrow width communicating portion therebetween, and to provide a partition with a porous film in the communicating portion, and to take the contents at the end of the filling portion The first opening is provided, and a second opening for opening the non-seal part is provided at a site opposite to the first opening.
[0005]
Hereinafter, the present invention will be described in detail with reference to the drawings. FIG. 1 is a front view and a cross-sectional view of a filling seal of a pouch according to the present invention and a finish cut.
Since gelled medicine contains moisture, it is necessary to take measures to prevent corruption, for example, retort sterilization or aseptic packaging.
The retort sterilization step (hereinafter referred to as retort treatment) is contained in the contents of the packaging material by holding at a temperature of 100 to 130 ° C. for 5 to 30 minutes in a pressurized and heated container, or Kill attached bacteria.
However, in retort processing, if there is a risk that the medicinal components may decompose or react with other components as a result of exposure to a considerably high temperature as described above, aseptic packaging may be used as another method. You can also
Aseptic packaging can be referred to as <a method of packaging aseptic contents on an aseptic packaging material in an aseptic environment>.
The sterilization of the packaging material such as the pouch of the present invention can be performed by dipping in a hydrogen peroxide solution and drying in a closed system.
[0006]
Therefore, the packaging material for aseptic packaging does not require much heat resistance, but the packaging material for retort treatment requires heat resistance, and various configurations are possible as packaging materials for that purpose. Such a laminate configuration is given as an example.
PET / PE
PET / CPP
ON / AL / PE
PET / AL / CPP
Here, the abbreviations are as follows. PET: polyethylene terephthalate film, ON: stretched nylon film, PE: heat-resistant polyethylene resin layer, CPP: polypropylene resin layer, AL: aluminum foil.
[0007]
In order to form the pouch of the present invention using the packaging material as described above (hereinafter referred to as a film), the two films are preliminarily overlapped with the sealing surface inside, and the filling portion and the injecting portion of the contents are provided. Remove and seal. The shape of the seal is preferably a deformed seal that will be the final gel shape. Next, the contents are filled and the filling port is sealed.
When the above process is performed by an aseptic packaging method, the processing related to bacteria is completed by using a dedicated packaging system.
On the other hand, in the case of the retort treatment, the pouch that has been filled and sealed at the filling port is sterilized by heating at a high temperature as described above in the autoclave for the retort treatment.
[0008]
As described above, when the two films are overlapped, sealed, filled, and hermetically sealed, the first cut 2 is provided as shown in FIG. A cut 3 is provided. The first cut 2 is opened by the patient from the first cut and serves as a sucking mouth for taking the gel-like medicine, but the second cut 3 is opened before opening the first cut. In addition, since air is supplied from the back of the pouch when the medicine is sucked, the gel is not exhausted and the function of smoothly sucking into the patient's mouth is achieved.
FIG. 1 (B), in the sealing, a method of interposing the porous film between the housing portion and the unsealed portion of the content provided unsealed portion communicating with the accommodating portion of the contents, the PP ₀ A sectional view is shown in FIG. 2 (A), and an enlarged view of the communicating portion is shown in FIG. 2 (B).
If the gel-like medicine in the contents is easy to release water, if a vent hole is provided on the side opposite to taking it, it will ooze out or spill out when the taking off water is taken. Among them, there is a high possibility of containing medicinal ingredients, and not only the whole amount of medicinal ingredients can not be taken, but also around the mouth and clothes, etc., and it cannot be said that it is a preferred medicine. In the case of such a medicine, the folded porous film is sandwiched between the communicating portions so that the water separated from the air vent on the opposite side does not bleed out or spill out, and as shown in FIG. The porous film adheres by partial sealing, but the porous film allows air to permeate but does not allow liquid to permeate. The porous films do not have heat-sealing properties, and the sealing resin layer on the inner surface of the pouch has no heat. Select one with sealing properties. The function of the porous resin film at the time of taking, as shown in FIG. 3 (C), is to open air through the porous film from the opening part of the non-sealing part by opening the second opening part, It makes it possible to inhale medicine smoothly. As the porous film, a fluorine porous film or a nonwoven fabric laminated with perforated PET or CPP can be used.
[0009]
In taking the medicine packaged by the pouch of the present invention, the pouch is opened from the first and second cut ends. A material film, for example, a method of weakening a tear line portion such as PET or ON is preferable. As a weakening method, a known method such as a half cut with a cutter or weakening with a carbon dioxide laser can be used.
[0010]
When a patient takes a gel-like medicine, the shape is preferably a rocket-like shape as shown in FIG. 1 for inhaling from the first opening. What is necessary is just to design the type to do in the form of a medicine.
The slipperiness between the innermost surface material constituting the packaging material and the gel material of the contents, in other words, the releasability of the innermost surface material may also be related. There is also a solution to the shape considered in the mold.
[0011]
[Action]
According to the pouch according to the present invention, since the entire amount of the gel-like medicine is taken at the time of taking, there is no problem that the medicinal effect becomes insufficient.
The dosage form and packaging form are easy to take for the elderly.
[0012]
【Example】
A gelatinous drug (in this example, sugar-containing gelatin is used, and the following expression is a drug) is put in the bag of the present invention, retorted, and after a predetermined inspection, a predetermined quantity is put in a carton and is commercially available. The condition was evaluated after storage for 6 months and 1 year.
The outline is as follows. First, the specifications of the packaging film used are
PET12μm / Dry Lami / CPP30μm
(The film abbreviations are as described above.)
The contents are 20g of gel medicine. The sealing shape of the pouch used in this example is tapered so that the gel-like medicine is easy to come out, as in FIG. 1B described above, and is the opening side that is opened for taking. Easy cut to make a vent on the opposite side. A non-seal part is provided in communication with the filling part, and as a countermeasure against water separation, the fluorine film is folded in two into a tape shape, drawn out for a predetermined length, sandwiched and heated with the packaging material of the above specifications. Sealed.
A cut for easy cutting was made at a depth of about 5 μm by a carbon dioxide laser on the surface of PET 12 μm as a base film of the packaging film.
The conditions for the retort treatment were sterilization at 120 ° C. for 10 minutes.
As mentioned above, after 6 months and 1 year, taking a 70-80-year-old elderly as a panel and taking a dose test, there was no panel that showed resistance in the first and second opening and taking. .
[0013]
【The invention's effect】
Since the medicine packaged by the pouch according to the present invention can be taken with certainty without leaving the entire amount of medicine to be taken, more reliable medicinal effects can be expected.
The fact that it can be taken even by elderly people by simply taking the gel-like medicine and the easy action of opening the pouch has a great effect on future medical care.
[Brief description of the drawings]
FIG. 1 is a front view of a packaging example of a pouch according to the present invention.
FIG. 2 is a cross-sectional view and a partially enlarged view for explaining a packaging example according to the present invention.
FIG. 3 shows a packaging example according to the prior art.
[Explanation of symbols]
1. Drug.
2. First cut.
3. Second cut.
4). Non-seal part.
5. Porous resin film.
S. Seal part.
3G. Cut line of the second opening.

Claims (1)

In the packaging form of the deformed seal of the four-sided seal that wraps the content that will eventually become a gel, the heat filling pattern from one side to the other inside the pouch, and the small area non-filling part A seal portion is provided so as to communicate with each other through a communication portion having a narrow width therebetween, a partition made of a porous film is provided at the communication portion, and a first portion for taking contents at an end portion of the filling portion And a second opening for opening the non-seal portion at a portion opposite to the first opening.

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