JP4054698B2 - Cosmetics containing an extract from squid follicular gland and method for collecting extract from squid follicular gland - Google Patents
Cosmetics containing an extract from squid follicular gland and method for collecting extract from squid follicular gland Download PDFInfo
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- JP4054698B2 JP4054698B2 JP2003064617A JP2003064617A JP4054698B2 JP 4054698 B2 JP4054698 B2 JP 4054698B2 JP 2003064617 A JP2003064617 A JP 2003064617A JP 2003064617 A JP2003064617 A JP 2003064617A JP 4054698 B2 JP4054698 B2 JP 4054698B2
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- Prior art keywords
- squid
- extract
- gland
- solution
- viscous substance
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Description
【０００１】
【発明の属する技術分野】
本発明は従来利用されることの無かった、イカの内臓由来の新規原料を含有する化粧料に関するもので、更に詳細にはイカの包卵腺より可溶化処理の後に、抽出された粘性物質を含有した化粧料及び前記粘性物質の採取方法に関する。
【０００２】
【従来の技術】
イカは産卵の際、卵は無色透明なゼリー状の材料に包まれている。このゼリー状の物質は産卵の前に包卵腺の中に原料として蓄積され、それが産卵の際に使われている。従来、イカの包卵腺を含む内蔵類は、ほとんど利用されることなく廃棄されていて、わずかに練り物類、中華料理の食材として利用されているのみであった。この包卵腺に蓄積されたゼリー状物質の利用については全く検討されたことが無く、更には抽出、精製方法についても知られていなかった。
【０００３】
【発明が解決すべき問題点】
本発明は、従来利用されることの無かったこのイカの包卵腺の新規利用を開拓することを目的としたもので、利用可能な原料の抽出、精製法を開発し、これを新規な化粧品原料として開発することを目指したものである。
【０００４】
【問題点を解決するための手段】
上記目的を達成するために鋭意検討の結果、包卵腺をアルカリによって処理することで抽出が可能となり、その抽出物は無色透明な粘性な物質であって、この粘性物質は化粧料原料として優れた特性を持つことを明らかにし、本発明を完成した。
即ち、本願の第１の発明の要旨はイカ包卵腺よりアルカリにより可溶化処理し、抽出した粘性物質を原料の一つとして含有することを特徴とした化粧料である。また、第２の発明の要旨はイカ包卵腺をアルカリにより可溶化処理し、得られた粘稠な溶液にアルコール及び中性塩を添加して沈殿物を生成させ、この沈殿物を濾別、回収することを特徴とするイカ包卵腺抽出物の採取方法である。
包卵腺は雌イカの腹を開いた際に中心部に位置する、比較的大きな内臓器官でこの内臓器官は産卵時期になると肥大化し、マイカでは５０ｇ程度、スルメイカでは２０ｇ程度の重量となる。
【０００５】
【発明の実施の形態】
本発明に用いることが出来るイカの種類に特に制限はないが、アカイカ科、ヤリイカ科、コウイカ科のスルメイカ、アカイカ、トビイカ、ヤリイカ、ケンサキイカ、アオリイカ、ジンドウイカ、スミイカ、モンゴイカ（別名マイカ、アカイカ、コウイカ、ゴウドウイカ、ムラサキイカ、バカイカ、ツメイカ、ニュウドウイカ、タコイカ、ドスイカ、シリヤケイカ、ハリイカ、ヒメイカ、コウイカ、ホタルイカ、ソデイカ、ダイオウイカ等）が望ましい。
集めた包卵腺をそのまま、あるいは乾燥させ、これをアルカリ性の溶液に入れ包卵線に含まれている粘性物質を可溶化して抽出を行う。用いるアルカリ性の溶液としては、NaOH、KOH等水酸イオンを持つ無機塩で、溶液としてのｐＨは１２以上が望ましい。これよりｐＨが低い場合には、可溶化を十分に行うことが出来ない。具体的には0.1〜1Ｎ程度の溶液を用いることが出来る。なお通常生体内に粘質物として存在するムチン（粘素）はアルカリで抽出する場合、β―位脱離を起こし分解を生じるが、本発明で使用するこの粘性物質の場合にはβ―位脱離を起こすことが無いために、従来β―位脱離を抑えるために行われるNaBH４等を用いる還元処理は不用であることを見いだした。
アルカリ処理時の温度は０℃〜室温付近が望ましい。０℃以下では可溶化が進行しにくく抽出の効率が悪く、室温を超える場合には粘性物質の分解が起こり、化粧料原料としての特性を損なうことになる。また処理時間はアルカリ溶液の濃度、温度に依存するが、１時間から１０時間の処理により可溶化、抽出は終了する。
【０００６】
この可溶化、抽出の終了した溶液にアルコール溶液、並びに中性塩を加えることによって、抽出した粘性物質を沈殿させることが出来る。用いるアルコール溶液はメタノール、エタノール、プロパノール、イソプロパノール等通常の糖タンパク質を沈殿させる有機溶媒を用いることが出来、例えば５０〜６０％のエタノール溶液等が使用出来る。さらにこのアルコール溶液にNaCl等の中性塩を含有させることによって、抽出物の沈殿を得ることが出来る。沈殿させた粘性物質は遠心分離、濾別等によって集めることが出来る。
使用できる中性塩に特に制限はなく、NaClの他にKCl、Na2SO４等水溶性の中性塩を用いることが出来る。
【０００７】
得られた沈殿は水に容易に溶解することが出来、その溶液の固有粘度を測定したところ30dl/g以上の範囲の固有粘度を持つ溶液であった。また得られた粘性物質はおおよそタンパク質35〜38％、糖質62〜65％、その他成分から構成された糖タンパク質で、約１００万〜２００万の分子量を持つと予想される。
【０００８】
本発明で得られた粘性物質は、無色透明、無臭で高い粘度を持ち、保湿、湿潤、増粘、乳化安定、乳化助剤、整肌、肌保護、潤滑、感触改善等の効果を得ることが出来る。具体的には基礎化粧品、化粧水（ローション）、乳液、クリーム、美容液、パック剤、下地クリーム、ファンデーション、口紅等の皮膚化粧料、シャンプー、リンス、ヘアーリキッド、ヘアークリーム等の頭髪化粧料等に用いることが出来、更に具体的には冬季の肌荒れ、乾燥による肌荒れ、髭剃り後の肌手入れ、洗髪、染毛・パーマ後の手入れ用化粧品に配合して使用することが出来る。
【０００９】
【実施例】
以下の実施例により本発明を具体的に説明するが、これによって本発明が限定されるものではない。
実施例１
スルメイカより取り出した包卵腺（湿重量約３ｇ）を水（１５０ｍＬ）に入れ、ホモジナイズした後に、NaOHを加えNaOH濃度として0.4Nの溶液とする。この溶液を４℃にし４時間ゆっくりと攪拌する。処理後の粘調な溶液に５０％エタノールとNaClを加え沈殿を生成させる。得られた沈殿を遠心分離によって回収し、イカ粘性物質（乾燥重量０．２ｇ）を得る。本粘性物質（０．２ｇ）を水１００ｍＬに溶解し、イカ粘性物質溶液を得た。
【００１０】
実施例２
実施例１で得られたイカ粘性物質溶液を使用し、以下の組成からなる栄養乳液を調製した。
組成 重量％
オリーブ油 10.0
スクワラン 1.0
ジブチルヒドロキシトルエン 0.1
香料 0.1
モノイソステアリン酸ジグリセリン 0.3
実施例１のイカ粘性物質溶液 1.0
ポリエチレングリコール400 12.0
ポリエチレングリコール1500 3.0
エタノール 5.0
パラオキシ安息香酸エステル 0.2
精製水 67.3
得られた栄養乳液は、保湿性を有し、べとつきがなく、良好な乳液であった。
【００１１】
実施例３
実施例１で得られたイカ粘性物質溶液を使用し、以下の組成からなる栄養クリームを調製した。
組成 重量％
プロピレングリコール 4.0
精製水 31.7
ミツロウ 5.0
マイクロクリスタリンワックス 7.0
固形パラフィン 4.0
実施例１のイカ粘性物質溶液 3.0
流動パラフィン 38.0
ラノリン 7.0
香料 0.2
パラオキシ安息香酸エステル 0.1
得られた栄養クリームはであった。
【００１２】
実施例４
実施例１で得られたイカ粘性物質を使用し、以下の組成からなる化粧水を調製した。
組成 重量％
実施例１のイカ粘性物質 0.2
精製水 99.8
得られた化粧水は、保湿性、べとつき、臭いが無く使用感に優れた化粧水であった。
【００１３】
【発明の効果】
以上述べたように、本発明は従来使用されていなかったイカの包卵腺より可溶化処理、抽出した粘性物質を化粧料原料に使用することができ、これを含有した化粧料は保湿性が良好でべとつきがない等の効果を奏する。[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a cosmetic containing a novel raw material derived from the internal organs of squid, which has not been used in the past, and more specifically, the extracted viscous substance after solubilization from the squid follicle gland. The present invention relates to a cosmetic and a method for collecting the viscous substance.
[0002]
[Prior art]
When squid lays eggs, the eggs are wrapped in a clear, transparent jelly-like material. This jelly-like substance is accumulated as a raw material in the ovulation gland before egg laying, and it is used for egg laying. Conventionally, the built-in type including the squid follicle gland is discarded with little use, and is only slightly used as a food for kneaded foods and Chinese dishes. The use of the jelly-like substance accumulated in the follicular gland has never been studied, and furthermore, the extraction and purification methods have not been known.
[0003]
[Problems to be solved by the invention]
The present invention aims to pioneer the new use of this squid follicular gland that has not been used in the past, and has developed a method for extracting and purifying available raw materials, which can be used as a novel cosmetic product. It aims to be developed as a raw material.
[0004]
[Means for solving problems]
As a result of intensive studies to achieve the above object, extraction is possible by treating the oviposition gland with alkali, and the extract is a colorless and transparent viscous substance, which is an excellent cosmetic raw material. As a result, the present invention was completed.
That is, the gist of the first invention of the present application is a cosmetic characterized by containing, as one of raw materials, a viscous substance that has been solubilized with an alkali from the cuttlefish gland and extracted. Further, the gist of the second invention is Rika solubilizing treatment by the alkali squid wrapped egg glands, to produce a precipitate by the addition of alcohol and neutral salts obtained viscous solution and the precipitate A method for collecting a cuttlefish ovarian gland extract characterized by filtering and collecting.
The follicular gland is a relatively large internal organ located in the center when the female squid's belly is opened. This internal organ enlarges at the time of spawning and weighs about 50 g for mica and about 20 g for squid.
[0005]
DETAILED DESCRIPTION OF THE INVENTION
There are no particular restrictions on the type of squid that can be used in the present invention, but the squid, squid, squid, squid, flying squid, squid, squid, squid, squid, squid, mongo squid (aka mica, squid, cuttlefish) , Gold squid, purple squid, squid, squid, new squid, octopus, squid, siliyakei, squid, Japanese squid, Japanese squid, firefly squid, green squid, squid squid, etc.).
The collected ovarian gland is left as it is or dried, and this is placed in an alkaline solution to solubilize and extract the viscous substance contained in the emboli. The alkaline solution used is an inorganic salt having hydroxide ions such as NaOH and KOH, and the pH of the solution is preferably 12 or more. If the pH is lower than this, solubilization cannot be performed sufficiently. Specifically, a solution of about 0.1 to 1N can be used. It should be noted that mucin (mucin) that normally exists as a mucilage in the living body, when extracted with alkali, causes β-position elimination and decomposition, but in the case of this viscous substance used in the present invention, β-position elimination. It has been found that the reduction treatment using NaBH 4 or the like conventionally performed to suppress the elimination of the β-position is unnecessary because no separation occurs.
The temperature during the alkali treatment is preferably 0 ° C. to around room temperature. Below 0 ° C., solubilization is difficult to proceed and the extraction efficiency is poor. When the temperature exceeds room temperature, the viscous material is decomposed and the properties as a cosmetic raw material are impaired. The treatment time depends on the concentration and temperature of the alkaline solution, but solubilization and extraction are completed by treatment for 1 to 10 hours.
[0006]
By adding an alcohol solution and a neutral salt to the solubilized and extracted solution, the extracted viscous substance can be precipitated. As the alcohol solution to be used, an organic solvent for precipitating normal glycoproteins such as methanol, ethanol, propanol and isopropanol can be used. For example, a 50 to 60% ethanol solution can be used. Furthermore, the precipitation of an extract can be obtained by making this alcohol solution contain neutral salts, such as NaCl. The precipitated viscous material can be collected by centrifugation, filtration or the like.
The neutral salt that can be used is not particularly limited, and water-soluble neutral salts such as KCl and Na 2 SO 4 can be used in addition to NaCl.
[0007]
The obtained precipitate could be easily dissolved in water, and when the intrinsic viscosity of the solution was measured, it was a solution having an intrinsic viscosity in the range of 30 dl / g or more. The obtained viscous substance is a glycoprotein composed of approximately 35 to 38% protein, 62 to 65% carbohydrate, and other components, and is expected to have a molecular weight of about 1 to 2 million.
[0008]
The viscous material obtained in the present invention is colorless and transparent, has no odor, has a high viscosity, and obtains effects such as moisturizing, wetting, thickening, emulsification stability, emulsification aid, skin conditioning, skin protection, lubrication, and touch improvement. I can do it. Specifically, skin care cosmetics such as basic cosmetics, lotions, milk lotions, creams, cosmetics, packs, base creams, foundations, lipsticks, hair cosmetics such as shampoos, rinses, hair liquids, hair creams, etc. More specifically, it can be used by blending it into cosmetics for rough skin in winter, rough skin due to drying, skin care after shaving, hair washing, hair dyeing / perm care.
[0009]
【Example】
The present invention is specifically described by the following examples, but the present invention is not limited thereby.
Example 1
Putting the oval gland (wet weight of about 3 g) removed from the common squid in water (150 mL) and homogenizing it, adding NaOH to make a 0.4N solution as NaOH concentration. The solution is brought to 4 ° C. and stirred slowly for 4 hours. 50% ethanol and NaCl are added to the viscous solution after the treatment to form a precipitate. The resulting precipitate is collected by centrifugation to obtain a squid viscous substance (dry weight 0.2 g). This viscous substance (0.2 g) was dissolved in 100 mL of water to obtain a squid viscous substance solution.
[0010]
Example 2
Using the squid viscous substance solution obtained in Example 1, a nutritional emulsion having the following composition was prepared.
Composition Weight%
Olive oil 10.0
Squalane 1.0
Dibutylhydroxytoluene 0.1
Fragrance 0.1
Diglycerol monoisostearate 0.3
Squid Viscous Substance Solution of Example 1 1.0
Polyethylene glycol 400 12.0
Polyethylene glycol 1500 3.0
Ethanol 5.0
P-Hydroxybenzoate ester 0.2
Purified water 67.3
The obtained nutritional emulsion was moisturizing, non-sticky, and was a good emulsion.
[0011]
Example 3
Using the squid viscous substance solution obtained in Example 1, a nutritional cream having the following composition was prepared.
Composition Weight%
Propylene glycol 4.0
Purified water 31.7
Beeslow 5.0
Microcrystalline wax 7.0
Solid paraffin 4.0
Squid Viscous Substance Solution of Example 1 3.0
Liquid paraffin 38.0
Lanolin 7.0
Fragrance 0.2
Paraoxybenzoic acid ester 0.1
The resulting nutritional cream was.
[0012]
Example 4
Using the squid viscous material obtained in Example 1, a lotion having the following composition was prepared.
Composition Weight%
Squid Viscous Material of Example 1 0.2
Purified water 99.8
The obtained lotion was a lotion with excellent moisturizing properties, stickiness, no odor and excellent usability.
[0013]
【The invention's effect】
As described above, the present invention can use a viscous material extracted from a squid follicle gland that has not been conventionally used as a cosmetic raw material. Good and non-sticky effects.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003064617A JP4054698B2 (en) | 2003-03-11 | 2003-03-11 | Cosmetics containing an extract from squid follicular gland and method for collecting extract from squid follicular gland |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003064617A JP4054698B2 (en) | 2003-03-11 | 2003-03-11 | Cosmetics containing an extract from squid follicular gland and method for collecting extract from squid follicular gland |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004269452A JP2004269452A (en) | 2004-09-30 |
| JP4054698B2 true JP4054698B2 (en) | 2008-02-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003064617A Expired - Fee Related JP4054698B2 (en) | 2003-03-11 | 2003-03-11 | Cosmetics containing an extract from squid follicular gland and method for collecting extract from squid follicular gland |
Country Status (1)
| Country | Link |
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| JP (1) | JP4054698B2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006263524A (en) * | 2005-03-22 | 2006-10-05 | Koken Co Ltd | Emulsifier and preparation using the same |
| KR101144773B1 (en) * | 2009-12-31 | 2012-05-11 | 김보라 | A processing method of liquid for anti-bacterial and anti-aging and whitening care |
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| Publication number | Publication date |
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| JP2004269452A (en) | 2004-09-30 |
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