JP4451690B2 - Food and beverage composition - Google Patents

Description

The present invention relates to a food / beverage product composition, and more particularly, to a food / beverage product composition suitable for improving the function of a circulatory system , such as green juice powder.

  In recent years, various lifestyle-related diseases have become a major social problem due to drastic changes in eating habits. Major lifestyle-related diseases include cardiovascular diseases such as hyperlipidemia, arteriosclerosis, hypertension, or syndrome X, which is a combination of these, resulting from a rapid increase in fat intake or calorie intake. There may be digestive problems such as vitamin deficiency and constipation due to a decrease in the amount of crude fiber consumed and vitamins. Moreover, the reduction | decrease of the amount of coarse fiber and vitamins to ingest also contributes to the said circulatory system disease. In addition to these, stress overload in modern society exacerbates these diseases. That is, it can be said that a means for improving the function of the circulatory system is demanded in the eating habits of modern people.

Based on this situation, various foods have been developed for the purpose of preventing these lifestyle-related diseases. Wherein the prevention of cardiovascular disease, for example, flavonoids such as rutin that are known to be useful (for example, see Patent Document 1). Further, crude fiber content and vitamins, as a useful means of replenishing the polyphenols, kale, the wheat young leaves or the like are ground finely, art "green juice" is that known for drinking are dispersed in water ( For example, see Patent Document 2, Patent Document 3, and Patent Document 4). In the formulation of view, a combination of rutin and galactooligosaccharides, techniques for processing health nutrition Solid that already known (e.g., see Patent Document 5). It raffinose is useful for constipation that already known (e.g., see Patent Document 6). However, there is no known food or beverage composition characterized in that it contains 1) rutin and 2) raffinose, and it is also possible to process this into a green juice dosage form. The treatment of rutin alone by treatment with rutin while improving gastrointestinal disorders such as constipation by administration of raffinose, rather than prevention of cardiovascular diseases with ingredients such as rutin alone It is not known at all that it is possible to prevent circulatory diseases better.

  Special table 2002-524522 gazette   Japanese Patent Laid-Open No. 2003-159036   JP 2002-186441 A   JP 2002-51753 A   Japanese Patent Laid-Open No. 9-238615   Japanese Patent Laid-Open No. 2001-97868   Tatsushi Kimura et al., Journal of Japanese Society of Hemorheology, Volume 5 (1), 2002, 13-16

  The present invention has been made under such circumstances, and it provides a new means for correcting the distortion of the modern diet and improving the function of the circulatory system more easily and accurately in the diet of modern people. The issue is to provide.

In view of such circumstances, the present inventors have sought a new means for correcting the distortion of the modern diet and improving the function of the circulatory system more simply and accurately in the modern diet. As a result of intensive research efforts, 1) rutin, 2) raffinose, etc. are contained, and this kind of improvement can be achieved by ingesting the food and beverage composition in the form of green juice. The present invention has been completed. That is, this invention relates to the technique shown below.
(1) A food and beverage composition comprising 1) 1 to 5% by mass of rutin and 2) 10 to 30% by mass of raffinose and / or melibiose .
(2) The food or beverage composition according to (1), wherein the rutin is contained as a processed product of buckwheat young leaves.
(3), which further contains a catechin 0.5-2 wt%, food or beverage composition according to (1) or (2).
(4) The food / beverage product composition according to (3), wherein the catechin is contained as a processed product of tea.
(5) The food or beverage composition according to any one of (1) to (4), which is a dry syrup preparation .
(6) The food / beverage composition according to ( 5) , wherein the food / beverage composition is dispersed in water and ingested in the form of green juice.

(1) Rutin which is an essential component of the food / beverage product composition of the present invention The food / beverage product composition of the present invention contains rutin as an essential component. Rutin is a flavonoid that is abundant in plants of the genus buckwheat, and is a component that has actions such as blood flow improving action and blood lipid improving action. In the food / beverage composition of the present invention, the form containing rutin can be, for example, dried, shredded, pulverized, and processed as a processed product of a plant belonging to the genus buckwheat, Extract from the body or its processed product using an organic solvent such as ethanol, remove the hydrophilic fraction by liquid-liquid extraction with butanol and water, and optionally purify using column chromatography with an ion exchange resin. However, it can also be separated into pure components. In addition, the plant belonging to the genus Poaceae that can be used is not particularly limited, but buckwheat (Fagopyrum esculentum), tartary buckwheat (Fagopyrum tataricum), flocked buckwheat (Fagopyrum dibotrys) and the like, and particularly preferable buckwheat can be exemplified. As the part to be used, young leaves and young stems are preferable, and as the young leaf young stems, green buckwheat leaves before and after flowering or green buckwheat stems are preferable, and these are 5 to 15 cm from the ground surface. After cutting and washing with water, it is cut to about 10 mm, and then is dried to a moisture content of 7% or less, preferably 4% or less by freeze-drying or preferably hot-air drying within 24 hours after plucking or cutting, and this is rolled. 90 to 1 using a high-speed mill or high-speed mill Was ground to about 0 mesh screen were created are particularly preferred. This is because such powder contains more rutin than ordinary buckwheat berries. In addition, by taking such a powder form, it is possible to take in ingredients that are preferable for improving lifestyle-related diseases such as crude fibers, vitamins, and chlorophyll. In food and beverage compositions of the present invention, including Yuryou such rutin it is 1 to 5 mass%, more preferably from 1.1 to 3 wt%. This is because if the amount is too small, the cardiovascular function improvement effect may not be achieved, and if the amount is too large, the content of other co-working components may be reduced and the bioavailability may be decreased.

<Production Example 1>
Buckwheat young leaves and young stems were cut at 10 cm to obtain 487 g. This was washed with water, and then air-dried at 40 ° C. for 72 hours. After chopping with a mixer, the mixture was pulverized with a high-speed pulverizer, sieved, and the fractions of 80 mesh pass and 100 mesh on were collected. Buckwheat young leaf powder 1 (yield 5.2 g) was obtained. The rutin content of this product was extracted with acetonitrile and quantified by HPLC (ODS 150 mm × 4.6 mm, 40% acetonitrile aqueous solution, ultraviolet part 220 nm, flow rate 1 ml / min.), And it was 2.6% by mass.

(2) Raffinose and / or melibiose, which are essential components of the food / beverage composition of the present invention, contain raffinose and / or melibiose as an essential component. Raffinose and / or melibiose is a moth Rakutoorigo sugar derived from 甜 vegetables sugar, La Finosu is not particularly preferred. Such a component has an action of inducing in the intestinal flora to a preferable one, and thus adjusting the flora to produce a substance useful for improving lifestyle-related diseases. Such an action works synergistically with the rutin, and has effects such as improvement of lifestyle-related diseases, prevention of deterioration, and prevention of onset. Such raffinose and / or melibiose already exists on the market, and such a commercial product can be purchased and used. In order to exhibit such an effect, the content of raffinose and / or melibiose is 10 to 30% by mass , and particularly preferably 13 to 20% by mass. If there is too little, there may be cases where the effect of improving and preventing lifestyle-related diseases such as cardiovascular function improvement effects may not be achieved. If too much, the content of other co-working components will be reduced and the bioavailability will be reduced. Because there exists. Furthermore, by improving the intestinal microflora, bowel movements are improved, thereby having a secondary effect of preventing a temporary increase in blood pressure during defecation from causing serious injury.

(3) Food / beverage product composition of this invention The food / beverage product composition of this invention contains the said essential component, and is ingested as a foodstuff or a drink, It is characterized by the above-mentioned. Examples of the form of the food and drink composition of the present invention include solubilization in an aqueous carrier such as a solid preparation for eating or swallowing solid substances such as granules, pills, tablets, capsules and powders as they are, or water. A dry syrup is preferably used by solubilizing or dispersing the dispersed liquid, powder or granule in an aqueous carrier at the time of use, and solubilized or dispersed in an aqueous carrier at the time of use to give a blue to green dispersion state. The dry syrup agent used in the so-called “green juice” form is particularly preferred. This is because by taking such a form, it is possible to ingest an amount of a food or beverage composition that is difficult to ingest in the solid form. In addition, as described above, when the rutin is contained as a buckwheat young leaf powder, the taste at this time can be ingested without feeling the bitterness of rutin. In the food-drinks composition of this invention, the arbitrary component normally used with a drink, a foodstuff, etc. can be contained besides this essential component. Examples of such optional components include colorants, flavoring agents, binders, excipients, disintegrants, dispersants, emulsifiers, solubilizers, coating agents, plasticizers, dragees, thickeners, and stabilizers. An agent etc. can be illustrated suitably. Furthermore, it can contain components suitable for improving and preventing lifestyle-related diseases such as cardiovascular diseases. As such components, for example, polyphenols that do not belong to rutin can be suitably exemplified, and as the polyphenols, catechin, resveratrol, proanthocyanidins, isoflavonoids and the like can be preferably exemplified, and among them, catechin is particularly preferable Preferred examples can be given. As catechins, tea-derived catechins are preferable, and the tea-derived catechins are preferably contained as green tea leaves dried, ground, chopped and powdered. Here, “cha” is a general term for plants belonging to the genus Camellia sinensis, and for example, “Camellia sinensis var. Siensis” which is a tea for green tea and “Asamika” which is a tea for tea. (Camellia sinensis var. Assamica) can be suitably exemplified, and green leaves of sinensis are preferably used. In order to produce gyokuro and the like, the green leaves include those grown with a limited amount of sunlight and those exposed to sunlight as much as possible to produce bancha. It is particularly preferable to use green leaves that have been exposed to sunlight as much as possible to produce bancha. This is because the content of catechin is high. In addition, by using dry green leaf pulverized product, components such as theanine can also be contained, and by such components, enhanced sympathetic nerve function can be sedated, thereby indirectly contributing to improvement of cardiovascular function. You can also In the food-drinks composition of this invention, it is preferable to contain 0.5-2 mass% of this catechin, More preferably, it is 0.8-1.5 mass%.

<Production Example 2>
Young leaves of tea grown in Hyuga were picked to obtain 265 g. This was washed with water, and then air-dried at 40 ° C. for 72 hours. After chopping with a mixer, the mixture was pulverized with a high-speed pulverizer, sieved, and the fractions of 80 mesh pass and 100 mesh on were collected. Tea powder 1 (yield 31 g) was obtained. The content of catechin in this product was extracted with acetonitrile and quantified by HPLC (ODS 150 mm × 4.6 mm, 40% acetonitrile aqueous solution, ultraviolet part 220 nm, flow rate 1 ml / min.), And it was 3.5% by mass.

  The food / beverage composition of the present invention preferably takes 1 to 5 g per day in one or several divided doses, and the content in a preferred form of the above components is 1 to 5% by mass of rutin, Catechin is 0.5 to 2% by mass and raffinose is 10 to 30% by mass, and it is preferable to ingest 2 to 5 g of the composition having such a configuration per day. The preferable daily intake of such components is 0.03 to 0.15 g of rutin, 0.015 to 0.06 g of catechin, and 0.3 to 0.9 g of raffinose. 2 to 5 g per day, preferably once or several times. By ingesting the food / beverage product composition of the present invention at such a dose every day for 4 weeks or more, the blood cell deformability is improved, the blood fluidity is improved, and the blood pressure is lowered. Have. Of particular note is the significant improvement in blood fluidity. Such blood fluidity can be measured as the whole blood passage time by the method using MC-FAN described in Non-Patent Document 1. That is, 200 μl of heparinized blood was applied to a microchannel array (Blood 6-7: manufactured by Hitachi Haramachi Electronics Co., Ltd.) having a width of 7 μm, a length of 30 μm, a depth of 4.5 μm, and 8736 lines, MC-FAN (Hitachi Haramachi Electronics) Kogyo Kogyo Co., Ltd.) was used to flow with a 20 cm water column difference, and the time for 100 μl to pass through was measured, and this could be used as the whole blood passage time.

  Hereinafter, the present invention will be described in more detail with reference to examples, but it is needless to say that the present invention is not limited to such examples.

<Example 1>
In accordance with the formulation shown below, “green juice”, which is a dry syrup preparation, which is a food and beverage composition of the present invention, was prepared. That is, the prescription ingredients were mixed well with a Henschel mixer to obtain the food / beverage composition 1 of the present invention.
(Prescription)
50 parts by weight of buckwheat young leaf powder of Production Example 1 (content of 1.25% by mass of rutin with respect to the entire food and beverage composition 1)
33.3 parts by mass of tea powder of Production Example 2 (content 1.19% by mass of catechin with respect to the entire food and beverage composition 1)
16.7 parts by mass of raffinose

<Example 2>
The food / beverage composition 2 of this invention was created according to the following prescription similarly to Example 1. FIG.
(Prescription)
50 parts by weight of buckwheat young leaf powder of Production Example 1 (content of 1.25% by mass of rutin based on the entire food and beverage composition 2)
50 parts by mass of raffinose

<Example 3>
The food / beverage composition 3 of this invention was created according to the following prescription similarly to Example 1. FIG.
(Prescription)
50 mass parts of buckwheat young leaf powder of Production Example 1 (content of 1.25% by mass of rutin with respect to the entire food and beverage composition 3)
33.3 parts by mass of tea powder of Production Example 2 (content 1.19% by mass of catechin based on the entire food and beverage composition 3)
Melibiose 16.7 parts by mass

<Comparative Example 1>
Comparative Example 1 was prepared according to the following prescription in the same manner as Example 1.
(Prescription)
83.3 parts by mass of tea powder of Production Example 2 (content 2.98% by mass of catechin relative to the whole of Comparative Example 1)
16.7 parts by mass of raffinose

<Comparative example 2>
As in Example 1, Comparative Example 2 was prepared according to the following formulation.
(Prescription)
50 parts by weight of buckwheat young leaf powder of Production Example 1 (content of 1.25% by mass of rutin relative to Comparative Example 2 as a whole)
33.3 parts by mass of tea powder of Production Example 2 (content 1.19% by mass of catechin with respect to the entire food and beverage composition 1)
16.7 parts by mass of sucrose

<Test Example 1>
About the said Examples 1-3, the comparative example 1, and the comparative example 2, the paneler 1 group 10 people were used and the continuous drinking test was done. That is, these preparations were dispersed in 180 g of 3 g water per day and were taken for 30 consecutive days. Blood was collected before and after the drinking test, heparinized, and then the whole blood passage time (seconds) was determined using MC-FAN. Separately, blood pressure was also measured before and after the test. These results are shown in Table 1 as average values. From this, it can be seen that in the food and beverage composition administration group of the present invention, the whole blood passage time is shortened and the blood fluidity is improved.

<Test Example 2>
A person who has a blood cholesterol level of 276 mg / dl and who has a tendency to hyperlipidemia continuously drinks 3 g of food / drink composition 1 of the present invention for 3 days a day for 30 days. I entered the normal range.

<Test Example 3>
When an anemic person with a red blood cell count of 2.9 million / legislative meter continuously drinks 3 g of food / beverage composition 1 of the present invention for 3 days a day for 30 days, it becomes 4.25 million / legitimate meter after the end of drinking. And anemia improved.

<Test Example 4>
A person with coldness at a body temperature of the sole of the foot of 34.2 ° C. continuously drinks 3 g of the food / beverage composition 1 of the present invention for 3 days a day for 30 days. It was done.

  The present invention can be applied to health foods useful for the prevention and improvement of lifestyle-related diseases.

Claims (6)

1) Rutin 1-5 mass% and 2) Raffinose and / or melibiose 10-30 mass% , The food-drinks composition characterized by the above-mentioned.   The said rutin is contained as a processed product of the young leaf of buckwheat, The food-drinks composition of Claim 1 characterized by the above-mentioned. Furthermore, catechin 0.5-2 mass% is contained, The food-drinks composition of Claim 1 or 2 characterized by the above-mentioned.   The food / beverage product composition according to claim 3, wherein the catechin is contained as a processed product of tea. It is a dry syrup agent, The food-drinks composition in any one of Claims 1-4 characterized by the above-mentioned. Wherein the dispersed in water in the form to be ingested in the form of a green juice, food and beverage composition according to claim 5.