JP4489694B2 - Adhesive sheet - Google Patents

Description

  The present invention relates to a pressure-sensitive adhesive sheet, and particularly relates to a pressure-sensitive adhesive sheet suitable as a medical pressure-sensitive adhesive tape or sheet to be affixed to the skin, such as a bandage, a pressure-sensitive adhesive bandage, and a haptic agent.

  A medical pressure-sensitive adhesive sheet is directly affixed to a person's skin and continues to affix for several minutes to several days depending on the purpose of use. In this pasted state, if the pressure-sensitive adhesive sheet is poor in air permeability and moisture permeability, the natural sweating from the skin is inhibited, and the skin surface on which the pressure-sensitive adhesive sheet is pasted may become stuffy and cause skin irritation. Therefore, in order to prevent such stuffiness, a medical pressure-sensitive adhesive sheet has been proposed in which an adhesive is provided on the entire surface of a non-permeable support and the sheet is then perforated. The air permeability is insufficient and is not always satisfactory.

  On the other hand, as another countermeasure against stuffiness, a material having air permeability and moisture permeability such as a woven fabric, a knitted fabric, a nonwoven fabric, a porous urethane film, or various organic polymer films subjected to perforation treatment is used, and There has also been proposed a medical pressure-sensitive adhesive sheet in which a pressure-sensitive adhesive is not provided on one or both surfaces of a support but is partially provided so as to ensure a gas flow path such as a stripe shape, a dot shape, or a lattice shape.

  An object of the present invention is to provide an adhesive sheet excellent in air permeability or moisture permeability, preferably an adhesive sheet excellent in waterproofness.

The present invention has the following features.
(1) on at least one side supporting region thereof, Hajojo a cohesive adhesive layer is plural rows, a pressure-sensitive adhesive sheet thus provided by the transfer,
The support is a woven fabric, a knitted fabric, a nonwoven fabric made of an organic polymer that is difficult to wet with water, or a woven fabric, a knitted fabric, a nonwoven fabric that has been subjected to a water repellent treatment, or is easily wetted with water. A woven fabric, knitted fabric, or nonwoven fabric made of an organic polymer, which has been subjected to water repellent treatment, whereby the support has breathability or moisture permeability and is waterproof.
The space between the wavy adhesive layers adjacent to each other on the support is also formed between the wavy pressure-sensitive adhesive layers.
The pressure-sensitive adhesive layer and the inter-strip space located in the center of the plurality of strips of adhesive layers and the inter-strip spaces proceed in a wavy manner without interruption from one end of the support to the other end, and the center The adhesive layer and the interstitial space located on both sides of the adhesive layer and the interstitial space located at the end of the support extend to the end part lateral to the wave-shaped traveling direction. Is interrupted, and
Defined width Article between space and by the product of the thickness of the adhesive layer, the cross-sectional area of該条between space state, and are ² × 10 ^-3 cm 2 or less,
With these configurations, air permeability or moisture permeability and waterproofness are ensured with respect to the thickness direction of the support and with respect to the lateral direction through the interstitial space.
Adhesive sheet.
(2) pressure-sensitive adhesive sheet according to (1) a medical.

The pressure-sensitive adhesive layer is not provided on the entire surface of one side or both sides of the support, but is provided in a strip shape on one or both sides, so that the space between the strips functions well as an air passage. In addition, since the support has air permeability or moisture permeability, preferably waterproof, and the space cross-sectional area between the above stripes is a small cross-sectional area of 2 × 10 ⁻³ cm ² or less, It is also possible to prevent water from entering the space from the outside.
(2) The following inventions are preferred embodiments of the invention, and their functions and effects will be clarified by the following description.

As the support, one having air permeability or moisture permeability, preferably waterproof is used. In general, a porous sheet made of a material that has a large contact angle with water and hardly wets with water, or a porous sheet made of a material that easily gets wet with water, but the water-repellent treatment of the porous sheet is exemplified as a preferable one. The
Examples of porous sheets made of materials that are difficult to wet with water include polyolefins such as polyethylene, polypropylene, polybutene, ethylene-propylene copolymer, ethylene-vinyl acetate copolymer, and ethylene-ethyl acrylate copolymer, or polyurethane and polyester. Examples thereof include perforated films made of organic polymers such as other plastics such as polyamide, foamed sheets having open cells, woven fabrics, knitted fabrics, non-woven fabrics, and papers.
Examples of the porous sheet made of a material that easily wets water include woven fabrics, knitted fabrics, nonwoven fabrics, paper, and polyvinyl alcohol perforated films made of organic polymers such as cotton, cellulose, and polyvinyl alcohol. A porous sheet made of a material that easily wets water is used after being subjected to water repellent treatment with a known water repellent.
In addition, the porous sheet of the material which does not easily get wet with water is used after being subjected to water repellent treatment as necessary.
The support may be non-stretchable, or may be stretchable in the vertical direction and / or the horizontal direction.

  As the pressure-sensitive adhesive, various types known or practically used in the field of medical pressure-sensitive adhesive sheets can be used in the present invention. In particular, acrylic adhesives and rubber adhesives with less skin irritation are preferred.

  In the present invention, the pressure-sensitive adhesive is provided in a plurality of strips on one or both sides of the above-described support, and a space functioning as an air passage is provided between the strips. Hereinafter, this space will be referred to as a streak space. The thickness of the strip-like pressure-sensitive adhesive layer may be appropriately determined depending on the properties of the pressure-sensitive adhesive used and the purpose of use of the pressure-sensitive adhesive sheet of the present invention, but is generally about 5 to 200 μm, particularly about 10 to 100 μm. Is preferred. On the other hand, the width of the pressure-sensitive adhesive layer is about 0.5 to 10 mm.

  The pressure-sensitive adhesive layer may have a linear shape, a wavy shape, or other shapes as long as the interstitial space can be secured. However, in general, a wavy line with a small change with time in the cross-sectional area of the space between lines is particularly preferable. The shape of the wavy line may be a waveform that rises and falls symmetrically with respect to the base line, such as a sine curve, pseudo sine curve, triangular wave, or arc wave, and only one side of the base line has an arc, triangle, ellipse, or other shape. It may be a waveform that surfs in the form. Regardless of the waveform, the waveform width and wave period can be appropriately set according to the purpose of use of the present invention.

The interstitial space has a space sectional area of about 2 × 10 ⁻³ cm ² or less, particularly about 1 × 10 ⁻³ cm ² or less. However, if the cross-sectional area is too small, the air permeability based on the presence of the interstitial space of the pressure-sensitive adhesive sheet is lowered, so that it is preferably about 1 × 10 ⁻⁴ cm ² or more. By using the above-mentioned waterproof support and making the interstitial space a small cross-sectional area, water can be effectively prevented from entering the interstitial space based on the surface tension of water and the high viscous flow resistance. be able to.

  As long as the above-described space cross-sectional area is within a range that can be ensured, the inter-spaces may have various cross-sectional shapes. For example, a square, a wide rectangle, a deep groove rectangle, a trapezoid and the like are exemplified. When the thickness of the pressure-sensitive adhesive is about 10 to 100 μm as described above, the width of the space between the stripes, that is, the distance between the two adjacent pressure-sensitive adhesive layers is suitably about 1 to 3 mm.

  The pressure-sensitive adhesive layer can be formed on one side or both sides of the support by various methods well known in the art. Note that the pressure-sensitive adhesive layer may be formed only at a necessary location on the support, but if the pressure-sensitive adhesive layer is not present at the end of the support, it will be formed at the end of the support during use of the pressure-sensitive adhesive sheet of the present invention. Fraying may occur and easily peel from the skin. In such a case, the fraying can be prevented and the problem of peeling from the skin can be improved by forming the pressure-sensitive adhesive layer even at the end of the support.

Regarding the production of the pressure-sensitive adhesive sheet of the present invention, the shape of the pressure-sensitive adhesive layer is pre-patterned, and the pressure-sensitive adhesive layer pattern is screen-printed on almost the entire surface on one side or both sides of the continuously running support, computer control It is preferable that the film is continuously formed by drawing by the above method, combing method described later, or other methods.
In the above combing method, the pressure-sensitive adhesive paint is applied to substantially the entire surface of the temporary base sheet continuously running at a constant line speed, and then fixed in a direction perpendicular to the traveling direction of the temporary base sheet. After removing a part of the pressure-sensitive adhesive paint layer applied with a comb having a number of scratches reciprocating at a speed and finally drying the wavy pressure-sensitive adhesive paint layer remaining on the temporary substrate sheet The pressure-sensitive adhesive layer is transferred to the support sheet. According to this method, various corrugated pressure-sensitive adhesive layers can be formed by adjusting the line speed of the temporary base sheet, the reciprocating speed of the comb, the reciprocating motion itself, the number of comb scrapes, etc. it can. When using a support sheet that allows combing of the pressure-sensitive adhesive paint layer before drying, a support sheet may be used instead of the temporary base sheet described above. In that case, the transfer step can be omitted.
The support of the pressure-sensitive adhesive sheet piece cut into a desired shape and size from the long sheet manufactured by the above method has the pressure-sensitive adhesive layer substantially spread over substantially the entire surface including its end. Therefore, there is no fraying problem as described above.

Hereinafter, the present invention will be described in more detail with reference to the drawings.
FIG. 1 is a partial plan view of an embodiment of the present invention, and FIG. 2 is a partially enlarged sectional view taken along line XX in FIG. In FIGS. 1 and 2, 1 is a support, 2 is a sine-curved pressure-sensitive adhesive layer, and 3 is a space between the pressure-sensitive adhesive layers 2 and 2. Since the interstitial space 3 also exists between the pressure-sensitive adhesive layers 2, 2, it has a sine curve shape, and its cross-sectional area, that is, the product of the width W of the inter-spaces 3 and the thickness T of the pressure-sensitive adhesive layer 2 It has the size described above.

Example 1
Using a release paper with one side treated with silicone as a temporary base sheet, 10 parts by weight of 2-hydroxyethyl acrylate and 90 parts by weight of 2-ethylhexyl acrylate on the silicone-treated side of the release paper by the combing method described above 1 is used to form a large number of sine curve-shaped strips as shown in FIG. 1, and then dried to finally form a pressure-sensitive adhesive layer on the release paper with a thickness of 25 μm. On a support made of a porous polyurethane film (manufactured by Okura Kogyo Co., Ltd.). An adhesive sheet having 5 × 10 ⁻³ cm ² , a sine curve period of 100 mm, and a sine curve amplitude of 50 mm was obtained.

Example 2
A pressure-sensitive adhesive sheet different from Example 1 was obtained only in that the width of the interstitial space was 3 mm and the cross-sectional area of the interstitial space was 1.5 × 10 ⁻³ cm ² .

Example 3
A pressure-sensitive adhesive sheet different from Example 1 was obtained only in that the thickness of the pressure-sensitive adhesive layer was 100 μm and the cross-sectional area of the interstitial space was 1.0 × 10 ⁻³ cm ² .

Comparative Example 1
Using a release paper having a silicone treatment on one side as a temporary base sheet, 10 parts by weight of 2-hydroxyethyl acrylate and 90 parts by weight of 2-ethylhexyl acrylate are copolymerized on the silicone-treated surface of the release paper The resulting acrylic acid-based pressure-sensitive adhesive solution is applied to the entire surface without providing any interstitial spaces, then dried, and finally the pressure-sensitive adhesive layer on the release paper is composed of a 25 μm thick porous polyurethane film (manufactured by Okura Kogyo Co., Ltd.). It moved on the support body and obtained the 50-micrometer-thick adhesive sheet of the adhesive layer in this way.

Comparative Example 2
A pressure-sensitive adhesive sheet different from Example 1 was obtained only in that the width of the interstitial space was 5 mm and the cross-sectional area of the interstitial space was 2.5 × 10 ⁻³ cm ² .

Comparative Example 3
A pressure-sensitive adhesive sheet different from Comparative Example 1 was obtained only in that the thickness of the pressure-sensitive adhesive layer was 100 μm.

Comparative Example 4
A pressure-sensitive adhesive sheet different from Example 2 was obtained only in that the thickness of the pressure-sensitive adhesive layer was 100 μm and the cross-sectional area of the interstitial space was 3.0 × 10 ⁻³ cm ² .

Comparative Example 5
A pressure-sensitive adhesive sheet different from Comparative Example 2 was obtained only in that the thickness of the pressure-sensitive adhesive layer was 100 μm and the cross-sectional area of the interstitial space was 5.0 × 10 ⁻³ cm ² .

  Each pressure-sensitive adhesive sheet of Examples 1 to 3 and Comparative Examples 1 to 5 was stored at 60 ° C. for 1 day, and then subjected to the following test.

Test method for moisture permeability: 10 cc of distilled water was collected in a weighing bottle with an inner diameter of 38 mm and a height of 40 mm, and a 4 × 4 cm square adhesive sheet piece was attached to the mouth of the weighing bottle with the adhesive layer facing down. It was put into a constant temperature and humidity chamber set at a temperature of 40 ° C. and a relative humidity of 30% and left for 24 hours. The moisture permeability (g / m ² , 24 hours) was calculated by the following formula from the difference in weight before and after being left for 24 hours in a constant temperature and humidity chamber of the weighing bottle with the adhesive sheet piece attached. The weight was measured with a direct balance (minimum scale: 1/1000 g).
Moisture permeability = (weight before leaving-weight after standing) x 882.192

  Test method for simmerability: A 2 × 1 cm square absorbent pad was placed at the center of a 4 × 3 cm square pressure sensitive adhesive sheet piece, which was affixed to the skin and immersed in warm water at 40 ° C. for 30 minutes. Next, peel off the adhesive sheet piece from the skin, and then check whether the skin at the application site is moistened white, and if sultry is not observed, pass from the viewpoint of breathability, if sultry is observed From the viewpoint of air permeability, it was rejected as not preferable.

  Test method for waterproofness: A 2 × 1 cm square absorbent pad was placed at the center of a 4 × 3 cm square pressure sensitive adhesive sheet piece, affixed to the skin, and immersed in warm water at 40 ° C. for 30 minutes. Subsequently, the adhesive sheet piece was peeled from the skin, and the presence or absence of water intrusion into the absorption pad was examined. When water intrusion was not recognized, it was accepted as preferable from the viewpoint of waterproofness, and when it was recognized, it was rejected as not preferable from the viewpoint of waterproofing.

  The above measurement results are shown in Table 1. As is clear from the table, each of the pressure-sensitive adhesive sheet pieces of Examples 1 to 3 showed excellent results in any test of moisture permeability, simmerability, and waterproofness. On the other hand, Comparative Example 1 and Comparative Example 3 having no interstitial space are excellent in waterproofness but have problems in moisture permeability and suffocation. On the other hand, Comparative Example 2, Comparative Example 4 and Comparative Example 5, which have interstitial spaces but have an excessive cross-sectional area, have a problem in waterproofness even though they have good moisture permeability and stuffiness.

  Since the pressure-sensitive adhesive sheet of the present invention is excellent in air permeability or moisture permeability, natural sweating is performed well even when applied for a long time, and the problem of stuffiness and skin irritation based on stuffiness is reduced. In addition, those having excellent waterproofness can be washed, showered, or bathed with the adhesive sheet attached. Further, fraying of the edge of the support and peeling phenomenon during use can be reduced or prevented. Therefore, the pressure-sensitive adhesive sheet of the present invention is suitable as a medical pressure-sensitive adhesive tape or sheet to be applied to the skin, such as a bandage, a pressure-sensitive adhesive bandage, and a haptic agent.

It is a partial top view of the Example of this invention. FIG. 2 is a partial enlarged cross-sectional view taken along line XX in FIG. 1.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Support body 2 Adhesive layer 3 Interstitial space formed between adhesive layers

Claims (2)

On at least one side supporting region thereof, Hajojo a cohesive adhesive layer is plural rows, a pressure-sensitive adhesive sheet thus provided by the transfer,
The support is a woven fabric, a knitted fabric, a non-woven fabric made of an organic polymer that is difficult to wet with water, or is a woven fabric, a knitted fabric, a non-woven fabric subjected to a water repellent treatment, or is easily wetted with water. Made of organic polymer, woven fabric, knitted fabric, non-woven fabric subjected to water repellent treatment, whereby the support has breathability or moisture permeability and is waterproof.
The inter-space between the wavy adhesive layers adjacent to each other on the support is also a wavy line by being present between the wavy adhesive layers,
The adhesive layer and the interstitial space located in the center of the plurality of adhesive layers and the interstitial space, proceed in a wavy manner without interruption from one end of the support to the other end, the center The adhesive layer and the interstitial space located on both sides across the adhesive layer and the interstitial space located at the end of the support extend to the end part present on the side with respect to the wavy traveling direction. Is interrupted, and
Defined width Article between space and by the product of the thickness of the adhesive layer, the cross-sectional area of該条between space state, and are ² × 10 ^-3 cm 2 or less,
With these configurations, air permeability or moisture permeability and waterproofness are ensured with respect to the thickness direction of the support and with respect to the lateral direction through the interstitial space.
Adhesive sheet. The pressure-sensitive adhesive sheet according to claim 1, which is for medical use.

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