JP4495979B2 - Scalp hair cosmetics - Google Patents

Description

  The present invention relates to a scalp hair cosmetic composition that is excellent in the effect of maintaining moisture in the scalp, suppressing inflammation and maintaining the scalp in a healthy state, and excellent in stability over time of the preparation.

  In general, it is well known that healthy hair can be grown by keeping the scalp healthy. Therefore, it has been conventionally performed to use scalp hair cosmetics containing a moisturizing agent and an anti-inflammatory agent in order to keep the scalp in a healthy state. However, the effects of these scalp and hair cosmetics are not sufficient, and preparations containing these components often have poor system stability, such as formation of starch over time upon storage.

  As a scalp hair cosmetic containing eucalyptus extract, in addition to a hair nourishing and hair restoring agent (Patent Documents 1 and 2, etc.) utilizing the hair growth action, a hair care product having a dandruff, itching and hair loss inhibiting effect (Patent Document 3) A hair quality improving agent (Patent Document 4) that retains moisture of hair and gives firmness and firmness is known. However, eucalyptus extract has no known anti-inflammatory action, and the water retention performance in Patent Document 4 is not sufficient.

JP-A-2-48514 JP 2000-154118 A Japanese Patent Laid-Open No. 9-104610 JP 2001-270811 A

  An object of the present invention is to provide a scalp and hair cosmetic that is excellent in the effect of maintaining moisture in the scalp and suppressing inflammation to keep the scalp in a healthy state.

  The present inventor uses the eucalyptus extract and the polyhydric alcohol together with at least one selected from a humectant and an anti-inflammatory agent to remarkably enhance the action of the humectant and the anti-inflammatory agent and to stabilize the formulation. Also found to improve.

That is, the present invention includes the following components (A) to (C):
(A) Eucalyptus extract
(B) Polyhydric alcohol
The present invention provides a scalp / hair cosmetic containing at least one selected from (C) (c1) a humectant and (c2) an anti-inflammatory agent.

  The scalp scalp hair cosmetic of the present invention is excellent in the effect of maintaining moisture in the scalp, suppressing inflammation and maintaining the scalp in a healthy state, and excellent in stability over time of the preparation.

  Eucalyptus extract component (A), Eucalyptus globulus [scientific name: Eucalyptus globulus, Eucalyptus] leaves, branches, etc., as it is or after dry pulverization, obtained by solvent extraction Commercial products can also be used.

  Solvents used for extraction are those usually used for extraction of plant components such as water, petroleum ether, n-hexane, toluene, dichloroethane, chloroform, ether, ethyl acetate, acetone, methanol, ethanol, propanol, butanol, ethylene glycol. , Propylene glycol, butylene glycol, and the like. Water, ethanol, propylene glycol, and butylene glycol are particularly preferable. You may use these in combination of 2 or more type. Moreover, normal conditions can apply the extraction conditions, for example, what is necessary is just to immerse or heat-reflux the said plant at 3-100 degreeC for several hours-several weeks. Eucalyptus extract can be used as an active ingredient of the scalp and hair cosmetic composition of the present invention as it is, but it can also be used by fractionating a highly active fraction by an appropriate separation means such as gel filtration, chromatography, precision distillation, etc. For example, macrocarpal A, B, C, D, E, F, G, H, I, J, K, am-1, etc., which are physiologically active substances contained in eucalyptus, may be used.

  The content of the eucalyptus extract of component (A) is sufficient to keep moisture in the scalp, and from the viewpoint of suppressing the inflammation and keeping the scalp in a healthy state and suppressing irritation, as a dry weight, 0.0001 to 5% by weight, more preferably 0.0005 to 1% by weight, and particularly preferably 0.0006 to 0.5% by weight.

  Examples of the polyhydric alcohol as component (B) include glycerin, propylene glycol, 1,3-butylene glycol, dipropylene glycol and the like. The content of the polyhydric alcohol of component (B) is preferably 0.001 to 10% by weight, particularly 0.01 to 5% by weight, based on the total composition, from the viewpoint of solubilizing the active ingredient and improving the stability of the composition.

  Among the components (C), the moisturizing agent of the component (c1) is blended in order to keep the moisture content of the skin and keep the scalp in good condition. Here, as the moisturizing agent, a polyhydric alcohol moisturizing agent is not included, and a plant extract having moisturizing properties is used. Examples of such plant extracts include button pi extract, achacha extract, hypericum extract, coleus extract, masaki extract, kouca extract, maikai flower extract, chorei extract, hawthorn extract, rosemary extract, duke extract, chamomile extract, odorifera extract, Ganoderma extract, Achillea millefolium extract, Aloe extract, Maronnier extract, Asunaro extract, Hibarata extract, Osmoine extract, Oat extract, Tuberose polysaccharide, Cordyceps extract, Barley extract, Orange extract, Giant extract, Salamander extract, Yakuinin Examples thereof include hypericum extract, chamomile extract, litchi extract, maronier extract, asunalo extract, and hibamata extract.

  Among the components (C), the anti-inflammatory agent of the component (c2) is blended in order to suppress inflammation and make the scalp healthy. Anti-inflammatory agents include compounds such as azulene, guaiazulene, diphenhydramine hydrochloride, hydrocortisone acetate, prednisolone, glycyrrhizic acid, glycyrrhetinic acid, mefenamic acid, phenylbutazone, indomethacin, ibuprofen, ketoprofen and their derivatives and their salts; Extracts, Kawaramugi Extract, Kyokyo Extract, Kyonin Extract, Gardenia Extract, Kumazasa Extract, Gentianana Extract, Comfrey Extract, Birch Extract, Mallow Extract, Tonin Extract, Peach Leaf Extract, Loquat Leaf Extract, etc. Compounds such as glycyrrhizic acid, glycyrrhetinic acid and derivatives thereof, and salts thereof are preferred.

  Two or more kinds of the moisturizer of component (c1) and the anti-inflammatory agent of component (c2) may be used in combination, and it is more preferable to use both components (c1) and (c2) in combination. The content of component (c1) is preferably 0.0001 to 10% by weight, particularly 0.0005 to 5% by weight, based on the total composition, from the viewpoint of sufficient moisturizing effect and promotion of penetration of component (A). The content of the component (c2) is preferably 0.0001 to 10% by weight, particularly preferably 0.001 to 5% by weight, based on the total composition, from the viewpoint of sufficient anti-inflammatory effect and stimulus suppression.

  In the scalp hair cosmetic of the present invention, a polar oil agent can be further blended as component (D) in order to solubilize active ingredients to promote penetration into the scalp and to improve feel and stability. . Examples of polar oils include higher alcohols, fatty acid alkyl esters, and fatty acid glycerides. Examples of the higher alcohol include lauryl alcohol, stearyl alcohol, oleyl alcohol, isostearyl alcohol, cetostearyl alcohol and the like. Examples of the fatty acid alkyl ester include methyl oleate, ethyl oleate, methyl isostearate, ethyl isostearate, isodecyl isononanoate, isotridecyl isononanoate, and isononyl isononanoate. Examples of fatty acid glycerides include monoglycerides, diglycerides and triglycerides of fatty acids having 8 to 18 carbon atoms. Of these, those that are liquid at 20 ° C and less than 100 mPa · s, especially less than 50 mPa · s, from the viewpoint of preventing the crystallization of active ingredients, dissolving the oil film consisting of lipids on the scalp, and promoting skin penetration Is preferred. Specifically, methyl isostearate, ethyl isostearate, isodecyl isononanoate, isotridecyl isononanoate, and isononyl isononanoate are preferred. The content of the polar oil agent is preferably 0.01 to 5% by weight, particularly 0.1 to 2% by weight, based on the total composition, from the viewpoint of promoting penetration of the active ingredient and improving touch.

  The scalp and hair cosmetic composition of the present invention may further contain an antioxidant. Examples of the antioxidant include vitamin C and its derivatives, erythorbic acid, propyl gallate, BHT (di-n-butylhydroxytoluene), BHA (butylhydroxyanisole) and the like. These are effective in preventing the occurrence of starch, which is considered to be a modification of component (A), and are particularly effective in improving the storage stability at high temperatures (for example, 50 ° C.). The content of the antioxidant is preferably 0.01 to 0.5% by weight, particularly 0.05 to 0.3% by weight, based on the total composition.

  The scalp hair cosmetic composition of the present invention may further contain a chelating agent. Examples of the chelating agent include edetic acid or a salt thereof, hydroxyethane diphosphonic acid or a salt thereof, and edetate such as disodium edetate, trisodium edetate, and tetrasodium edetate is particularly preferable. These are effective in preventing the occurrence of starch, which is considered to be a modification of component (A), and are particularly effective in improving the storage stability at high temperatures (for example, 50 ° C.). The content of the chelating agent is preferably 0.01 to 1% by weight, particularly 0.05 to 0.5% by weight, based on the total composition.

  Furthermore, it will be as follows if the content ratio of each component in the scalp scalp hair cosmetics of this invention is shown. The weight ratio of component (A): component (C) is preferably 1:10 to 1: 500 in order to maintain the scalp moisture and to suppress inflammation and keep the scalp healthy. In order to obtain better storage stability and hair growth effect, the weight ratio of component (A): component (B) in the relationship between component (A) and component (B) is 1:10 to 1: 2000, particularly It is preferable that it is 1: 40-1: 400.

  The scalp and hair cosmetic composition of the present invention preferably further contains a lower alcohol. Examples of the lower alcohol include methanol, ethanol, 2-propanol and the like, and ethanol is particularly preferable. The content of the lower alcohol is preferably 30% by weight or more, particularly 50% by weight or more based on the total composition.

  The scalp and hair cosmetic composition of the present invention may further contain a surfactant. Examples of the surfactant include a cationic surfactant, an anionic surfactant, and a nonionic surfactant. The surfactant is effective in solubilizing each component and improving the stability.

  Examples of cationic surfactants include cetyltrimethylammonium chloride, stearyltrimethylammonium chloride, aralkyltrimethylammonium chloride, and behenyltrimethylammonium chloride. From the viewpoint of smoothness during application, cetyltrimethylammonium chloride and stearyltrimethyl chloride are particularly preferred. Ammonium is preferred.

  Anionic surfactants include alkyl (or alkenyl) sulfates, polyoxyalkylene alkyl (or alkenyl) ether sulfates, alkane sulfonates, olefin sulfonates, alkyl benzene sulfonates, alkyl (or alkenyl) sulfosuccinates. Dialkyl (or dialkenyl) sulfosuccinate, polyoxyalkylene alkyl (or alkenyl) sulfosuccinate, alkyl (or alkenyl) ether carboxylate, polyoxyalkylene alkyl (or alkenyl) ether carboxylate, polyoxyalkylene alkyl ( Or alkenyl) ether phosphate, fatty acid salt, N-acyl glutamate, N-acyl taurate, N-acyl methyl taurine and the like. Of these, polyoxyalkylene alkyl (or alkenyl) ether phosphate, fatty acid salt, N-acyl glutamate, N-acyl taurate, N-acyl methyl taurine and the like are preferable.

  Nonionic surfactants include polyoxyalkylene alkyl ethers, polyoxyalkylene alkenyl ethers, higher fatty acid sucrose esters, polyglycerin fatty acid esters, higher fatty acid mono- or diethanolamides, polyoxyethylene hydrogenated castor oil, sorbitan fatty acid esters, poly Examples thereof include oxyethylene sorbitan fatty acid ester, polyoxyethylene sorbite fatty acid ester, alkyl polyglycoside, alkylamine oxide, and alkylamidoamine oxide. Of these, polyoxyalkylene alkyl ether, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbit fatty acid ester, and polyoxyethylene hydrogenated castor oil are preferable, and sorbitan fatty acid ester and polyoxyethylene alkyl ether are particularly preferable.

  Two or more surfactants can be used in combination, and the content thereof is preferably 0.01 to 1% by weight, particularly preferably 0.1 to 0.5% by weight, based on the total composition.

  In addition to the above components, the scalp and hair cosmetic composition of the present invention may contain various additive components used in normal hair cosmetics depending on the purpose. For example, a blood circulation promoter, a hair follicle activator, an antiseborrheic agent, an antibacterial agent, a refreshing agent, a preservative, salts, a pH adjuster, a propellant, a fragrance, a dye, an ultraviolet absorber, and the like can be blended.

  The scalp scalp hair cosmetic of the present invention can be in a desired form such as an aqueous solution, ethanol solution, emulsion, suspension, gel, aerosol, etc., for example, hair rinse, hair conditioner, hair treatment, hair lotion, hair pack, hair It can be in the form of cream, conditioning mousse, hair mousse, hair spray, shampoo, leave-on treatment and the like.

Examples 1-6 and Comparative Examples 1-6
The hair lotions shown in Table 1 were prepared according to a conventional method, and their storage stability was evaluated.

〔Evaluation methods〕
After each hair lotion was stored in a thermostatic bath at 5 ° C. for 1 month, the presence or absence of starch was visually observed. No occurrence of starch: “−”, slightly starch: “±”, starch was observed : “+”, A large amount of starch was observed: judged as “++”. The results are shown in Table 1.

Examples 7-8 and Comparative Examples 7-8
Hair lotions shown in Table 2 were prepared according to a conventional method, and the effect of reducing scalp tension and improving elasticity by using them was evaluated.

[Evaluation method of feeling of tension and elasticity]
80 subjects were divided into 4 groups, and 4 types of hair lotions were used continuously for 1 month. The person compared the effect of reducing the scalp feeling and improving the elasticity one month and three months later. The results are shown in Table 3.

Example 9
A hair lotion having the composition shown below was produced according to a conventional method.
(weight%)
Eucalyptus extract (0.2 wt% ethanol solution) 2.0
1,3-butylene glycol 1.0
Hypericum Extract 1.0
Glycyrrhetinic acid 0.1
Ethanol 40.0
Purified water balance

Example 10
A hair gel having the composition shown below was produced according to a conventional method.
(weight%)
Eucalyptus extract (0.2 wt% ethanol solution) 2.0
Dipropylene glycol 2.0
Asunaro extract (0.5 wt% ethanol solution) 1.5
Hibamata extract (0.5 wt% ethanol solution) 0.5
Diphenhydramine hydrochloride 0.2
Carboxyvinyl polymer (Carbopol 981; Noveon) 0.2
48 wt% potassium hydroxide 0.03
Ethanol 20.0
Purified water balance

Example 11
An aerosol having the composition shown below was produced according to a conventional method.
(Stock solution) (wt%)
Eucalyptus extract (0.2 wt% ethanol solution) 2.5
Propylene glycol 3.0
Maronnier extract (0.5 wt% ethanol solution) 1.0
Birch extract (0.5 wt% ethanol solution) 3.0
Ethanol 60.0
Purified water balance (propellant)
Carbon dioxide stock solution / carbon dioxide = 97/3

Claims (1)

Next ingredient (A) ~ (C)
(A) Eucalyptus extract: 0.0006 to 0.5 % by weight as dry weight
(B) Polyhydric alcohol selected from glycerin, propylene glycol, 1,3-butylene glycol and dipropylene glycol: 0.01 to 5 % by weight
(C) (c1) Hypericum extract, humectant selected from Maronieeki scan及 beauty bladderwrack extract 0.0005 to 5% by weight, and
(c2) grayed Richirurichin acid, glycyrrhetinic acid and anti-inflammatory agent selected salts thereof or et: 0.001 to 5 wt%
Contains scalp and hair cosmetics.