JP4523367B2 - Powder cosmetics - Google Patents

Description

  The present invention relates to a powder cosmetic, and more particularly to a powder cosmetic that stably contains a water-soluble drug such as a whitening agent or an anti-inflammatory agent.

Conventionally, whitening agents, ultraviolet absorbers, anti-inflammatory agents, vitamins, hormones, antihistamines, sebum suppressants, antiperspirants, and the like are sometimes blended in cosmetics in anticipation of their intended effects. In addition, various dosage forms such as lotion, milky lotion, cream, and powder cosmetics are used as cosmetics. Among these, powder cosmetics include, for example, foundation, white powder, body powder, whitening powder, emollient powder, and fragrance. There are powders.
In such a combination of a drug and a dosage form in cosmetics, as a conventional technique in which a water-soluble drug is blended in a powder cosmetic, for example, Patent Documents 1 to 1 are examples in which a whitening agent such as hydroquinone glycoside is blended in a foundation or the like. 3 is mentioned.

JP-A-61-207309 JP 2000-204019 A JP 2000-169339 A

However, in such a case, there is a problem that the stability is deteriorated as a result of the contact between the inorganic powder occupying multiple blends in the powder cosmetic base and a water-soluble drug component such as a whitening agent, and the drug is decomposed. It was.
In addition, when a water-soluble drug is blended in a powder base that does not substantially contain water, the water-soluble drug is blended in a powder state, but this water-soluble drug may have a large particle size unlike a normal powder. From the standpoint of usability, there are cases where it has an adverse effect such as roughness during use, and improvement has been desired from the viewpoint of usability.
The present invention has been made to solve such conventional problems, and is to provide a powder cosmetic containing a water-soluble drug, which is excellent in drug stability and usability. Objective.

The present invention is a powder cosmetic comprising the following components (1), (2) and (3).
(1) Hydrophobized powder 20 to 95% by mass
(2) Silicone spherical powder having an average particle size of 0.5 to 30 μm 1 to 30% by mass
(3) Water-soluble drug 0.01-20% by mass

  Here, the hydrophobized powder (1) is a hydrophobized powder in which the surface of the inorganic powder is surface-treated with one or more selected from a silicone compound and a tetraalkylammonium salt. Is preferred.

  Of these, the hydrophobized powder (1), in particular, treats the surface of the inorganic powder with a silicone compound having Si—H groups in the molecule, and then introduces linear or branched alkyl groups into the remaining Si—H groups. It is preferable that the powder be hydrophobized or an inorganic powder surface-treated with a tetraalkylammonium salt represented by the following general formula (1).

(In the formula, X is a chlorine atom or a bromine atom, and any one or more of R1 to R4 is a linear alkyl group having 10 to 22 carbon atoms, and the remainder is a straight chain having 1 to 10 carbon atoms. A chain alkyl group.)

  The silicone-based spherical powder (2) is one or more selected from the group consisting of an organopolysiloxane elastomer spherical powder, a methylsiloxane network polymer spherical powder, or a composite spherical powder using these as a mother powder. Is preferred.

  The water-soluble drug (3) is preferably one or more selected from the group consisting of hydroquinone glycosides and derivatives thereof, tranexamic acid and derivatives thereof, alkoxysalicylic acid and salts thereof.

  In the present invention, the powder cosmetic is a cosmetic taking a constitution of a component mainly composed of a powder part. Specifically, in the present invention, the powder cosmetic means a cosmetic in which the powder part occupies 60% by mass or more in the total amount. Therefore, the product form of the present powder cosmetic can be any form of cosmetic as long as this condition is satisfied.

  The powder cosmetic of the present invention is excellent in drug stability of a water-soluble drug compounded in the cosmetic, has no roughness and powderiness, and has excellent usability.

Next, the best mode for carrying out the present invention will be described.
(1) Hydrophobized powder The (1) hydrophobized powder used in the present invention is a powder obtained by hydrophobizing an arbitrary powder such as an inorganic powder, an organic powder, or a metal pigment. More specifically, talc, mica, kaolin, calcium carbonate, zinc white, titanium dioxide, red iron oxide, yellow iron oxide, black iron oxide, ultramarine, bismuth oxychloride, chromium hydroxide, titanium mica, aluminum oxide, cobalt, bitumen It is a powder obtained by subjecting carbon black, magnesium silicate, etc. to a hydrophobic treatment.

  As the type of the hydrophobizing treatment, a conventional method for preparing a hydrophobizing powder used for cosmetics can be used. For example, a higher fatty acid, a surfactant (anionic, cationic or nonionic) The surface of powder particles with one or more substances such as metal soaps, oils and fats, waxes, silicones, fluorine compounds, hydrocarbons, dextrin fatty acid esters, etc. Thus, a desired hydrophobized powder can be prepared.

  Among these hydrophobizing treatment methods, it is preferable to select one or more treatment methods selected from silicone treatment, tetraalkylammonium salt treatment, fluorine compound treatment and metal soap treatment. Tetraalkylammonium salt treatment (Japanese Patent Publication No. 4-45483) and silicone treatment are very suitable. By using the hydrophobized powder that has been treated with tetraalkylammonium salt (Japanese Patent Publication No. 4-45483) or silicone, the decomposition of the water-soluble drug can be further suppressed, and an excellent stability improving effect can be achieved.

  Here, the tetraalkylammonium salt treatment is a surface treatment with a tetraalkylammonium salt represented by the following general formula (1).

(In the formula, X is a chlorine atom or a bromine atom, and any one or more of R1 to R4 is a linear alkyl group having 10 to 22 carbon atoms, and the remainder is a straight chain having 1 to 10 carbon atoms. A chain alkyl group.)

  Of these, particularly preferred tetraalkylammonium salts are cetyltrimethylammonium chloride, behenyltrimethylammonium chloride, dimethyldistearylammonium chloride, dimethyldimyristylammonium chloride and dimethyldipalmitylammonium chloride.

  As a silicone treatment method, a silicone treatment having Si—H groups in the molecule is performed on the powder particle surface, and an alkyl group introduction treatment is performed on the Si—H groups remaining on the treated surface. A method is mentioned. The surface-treated powder subjected to the hydrophobization treatment is a known powder as a cosmetic powder, and its production method is not limited. For example, according to the methods disclosed in JP-A-63-113081, JP-A-11-343424, etc., first, silicone having Si—H groups is brought into contact with the powder particles to form the first layer silicone. Coating is performed, and then a linear or branched alkyl group of the second layer is introduced into the Si—H group on the surface of the powder particle coated with silicone by a hydrosilylation reaction or the like to perform a desired hydrophobizing treatment. A powder can be produced.

  As the silicone compound having a Si—H group, any compound can be used as long as it is a silicone compound having a Si—H group. For example, silicone oil, silicone resin, silicone wax and the like can be mentioned. The alkyl group to be introduced is preferably an alkyl group having 1 to 30 carbon atoms, particularly preferably 8 to 18 carbon atoms.

  In the present invention, the most preferable hydrophobized powder is obtained by treating the surface of an inorganic powder with a silicone compound having Si—H groups in the molecule, and then introducing linear or branched alkyl groups into the remaining Si—H groups. Hydrophobized powder.

  The total amount of the hydrophobized powder blended in the powder cosmetic according to the present invention is preferably 20 to 95% by mass, particularly 30 to 95% by mass from the viewpoint of drug stability and usability.

(2) Silicone spherical powder having an average particle size of 0.5 to 30 μm In the present invention, by using a silicone spherical powder, use such as roughness when a water-soluble drug is blended in a powder cosmetic base. The disadvantage of sex can be improved. Examples of the silicone-based spherical powder used in the present invention include one or more selected from the group consisting of an organopolysiloxane elastomer spherical powder, a methylsiloxane network polymer spherical powder, or a composite spherical powder using these as a mother powder. Can be mentioned.

Examples of commercially available products include organopolysiloxane elastomer spherical powders such as Trefill E-505C, Trefil E-506C, Trefill E-506S (Toray Dow Corning Silicone Co., Ltd.), and methylsiloxane network polymer spherical powder. Examples include Tospearl 145A (Toshiba Silicone Co., Ltd.), and examples of composite spherical powders using these as mother powders include Silicone Powder KSP100 (Shin-Etsu Chemical Co., Ltd.).
Usability is not improved even when spherical powders other than the silicone-based spherical powder are used.

  The average particle diameter of the silicone-based spherical powder of the present invention is 0.5 to 30 μm, and particularly preferably 1 to 20 μm from the viewpoint of usability.

The total amount of the silicone-based spherical powder blended in the powder cosmetic according to the present invention is preferably 1 to 30% by mass, particularly preferably 1 to 20% by mass. If it is less than 1% by mass, it is insufficient for improving the usability, and if it exceeds 30% by mass, the feeling of use may be deteriorated, such as reduction of fit and occurrence of skin slipping.
(3) Water-soluble drugs Water-soluble drugs used in the present invention include hydroquinone glycosides and derivatives thereof, tranexamic acid and derivatives thereof, alkoxysalicylic acid and salts thereof, L-ascorbic acid and derivatives thereof and salts thereof, glycyrrhizic acid And salts thereof. Of these, hydroquinone glycosides and derivatives thereof, tranexamic acid and derivatives thereof, alkoxysalicylic acid and salts thereof are particularly preferable.

  The total amount of the water-soluble drug blended in the powder cosmetic according to the present invention is preferably 0.01 to 20% by mass, particularly preferably 0.01 to 10% by mass.

  In the present invention, in addition to the above essential components, water, non-hydrophobic powder, oil, surfactant, lower alcohol, polyhydric alcohol, moisturizer, preservative, polymer (including coating agent) as necessary. Antioxidants, UV protection agents, fragrances, and other various agents can be contained in a qualitative and quantitative range that does not impair the intended effects of the present invention.

  Among the above optional components, non-hydrophobic powder includes talc, kaolin, mica, sericite (sericite), muscovite, biotite, phlogopite, synthetic mica, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate , Inorganic powders such as barium silicate, calcium silicate, magnesium silicate, metal tungstate, magnesium, silica, zeolite, barium sulfate, calcined calcium sulfate, calcined gypsum, calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder; polyamide Organic powders such as resin powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, styrene-acrylic acid copolymer resin powder, benzoguanamine resin powder, polytetrafluoroethylene powder, cellulose powder; titanium dioxide, zinc oxide Inorganic white pigments; inorganic red pigments such as iron oxide (Bengara) and iron titanate; inorganic brown pigments such as γ-iron oxide; inorganic yellow pigments such as yellow iron oxide and loess; black iron oxide and carbon Inorganic black pigments such as low-order titanium oxide; inorganic purple pigments such as mango violet and cobalt violet; inorganic green pigments such as chromium oxide, chromium hydroxide and cobalt titanate; inorganic blue pigments such as ultramarine and bitumen Pearl pigments such as titanium oxide-coated mica, titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, colored titanium oxide-coated mica, bismuth oxychloride, and fish scale foil; metal powder pigments such as aluminum powder and copper powder; .

The powder cosmetic of the present invention can be produced according to a conventional method for each product form.
Moreover, as a product form, as long as the essential requirement mentioned above is satisfied, it is possible to take all product forms in the category of the cosmetic powder. Specifically, the powder cosmetic of the present invention takes the form of a makeup base, foundation, white powder, body powder, whitening powder, emollient powder, fragrance powder, blusher, lipstick, mascara, eye shadow, eyeliner and the like. obtain.

  Hereinafter, preferred embodiments of the present invention will be described. The present invention is not limited to these. Further, the blending amount is mass% unless otherwise specified.

Examples 1-3, Comparative Examples 1-5
The white powder was prepared by the method described later in accordance with the formulation shown in Table 1 below, and the drug stability and usability (no powderiness and no roughness) were evaluated. The evaluation method is as described later. The results are also shown in Table 1.

1. After stirring and mixing each component of the production method 1-27, 28-33, which was uniformly heated and mixed, was added, mixed, pulverized, filled into an inner dish, and pressure-molded to obtain a white powder. .
In the table, for the hydrophobized powder, the first or second layer of a silicone compound having Si-H groups in the molecule treated on the surface of the inorganic powder is first layered, and then introduced into the remaining Si-H groups. The alkyl group was described as the second layer.

2. Evaluation Method (1) Drug Stability White powder was stored for 6 months under conditions of a temperature of 40 ° C. and a relative humidity of 75%. After the storage, the stored product was quantitatively analyzed by a conventional method using high performance liquid chromatography and evaluated according to the following criteria.
○: Residual rate of drug is 95% or more Δ: Residual rate of drug is 90% or more and less than 95% ×: Residual rate of drug is 85% or more and less than 90% XX: Residual rate of drug is less than 85%

(2) Usability A sensory test was conducted on the absence of powderiness and roughness by actually using white powder by 10 expert panelists. Evaluation results were evaluated according to the following four levels.
◎: Eight or more out of 10 judged good ○: Six to seven out of ten judged good △: Four to five out of 10 judged good ×: Three or less out of 10 were good Judgment

Example 4
A solid amphibious foundation was prepared by the method described later according to the formulation shown in Table 2 below. The obtained solid-type amphibious foundation was found to have the same effect as in Examples 1 to 3 in the same drug stability test and usability test as in Examples 1 to 3.

(Manufacturing method)
After stirring and mixing each component of 1-13, 14-20, which was uniformly heated and mixed, was added, mixed and pulverized. It was.

Example 5
A solid single-use foundation was prepared according to the formulation shown in Table 3 below. The obtained solid single-use foundation showed the same effect as in Examples 1 to 3 in the same drug stability test and usability test as in Examples 1 to 3.

(Manufacturing method)
After stirring and mixing each component of 1-12, 13-18, which is uniformly heated and mixed, is added and mixed, pulverized, filled into an inner dish and pressure-molded to form a solid single-use foundation. Obtained.

Example 6
The powdered white powder was prepared by the method described later according to the formulation shown in Table 4 below. In the same powder stability test and usability test as those performed in Examples 1 to 3, the obtained powdered white powder showed the same effect as in Examples 1 to 3.

(Manufacturing method)
After stirring and mixing the components 1 to 9, 10 and 11 were further added, mixed and pulverized to obtain powdered white powder.

Example 7
A solid amphibious foundation was prepared by the method described below according to the formulation shown in Table 5 below. The obtained solid-type amphibious foundation was found to have the same effect as in Examples 1 to 3 in the same drug stability test and usability test as in Examples 1 to 3.

(Manufacturing method)
After stirring and mixing the components 1 to 14, uniformly mixed 15 to 21 was added, mixed and pulverized, and molded into an intermediate dish to obtain a solid-type dual-use foundation.

Claims (3)

A powder cosmetic comprising the following components (1), (2) and (3):
(1) Hydrophobized powder 20 to 95% by mass
(2) Silicone spherical powder having an average particle size of 0.5 to 30 μm 1 to 30% by mass
(3) Water-soluble drug 0.01-20% by mass
Hydrophobic treatment powder (1) in which the surface of inorganic powder is treated with a silicone compound having Si—H groups in the molecule, and then linear or branched alkyl groups are introduced into the remaining Si—H groups Or an inorganic powder surface-treated with a tetraalkylammonium salt represented by the following general formula (1),
Wherein the water soluble drug (3), hydroquinone glycoside, tranexamic acid and its salts, and at one or more kinds selected from the group consisting of alkoxy salicylic acids and salts thereof, in powder content total amount of the cosmetic, 60 wt Powder cosmetics characterized by being at least% .

(In the formula, X is a chlorine atom or a bromine atom, and any one or more of R1 to R4 is a linear alkyl group having 10 to 22 carbon atoms, and the remainder is a straight chain having 1 to 10 carbon atoms. A chain alkyl group.) The powder cosmetic according to claim 1, wherein water is not substantially blended. The silicone-based spherical powder (2) is one or more selected from the group consisting of an organopolysiloxane elastomer spherical powder, a methylsiloxane network polymer spherical powder, or a composite spherical powder using these as a mother powder. The powder cosmetic according to claim 1 or 2 .